A longitudinal molecular surveillance study of human polyomavirus viremia in heart, kidney, liver, and pancreas transplant patients

PV16000 Study Group

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

In this study of 263 heart, kidney, liver, and pancreas transplant patients, BK virus (BKV) and JC virus (JCV) DNAemia were observed most commonly in kidney and/or pancreas transplant patients (26%), although they were also observed, to a lesser extent, in heart (7%) and liver (4%) transplant patients. The majority of episodes of polyomavirus DNAemia were subclinical, although, in some cases, BKV DNAemia was associated with kidney rejection, and JCV DNAemia was accompanied by nonspecific symptoms. Hence, BKV and JCV DNAemia are not uncommon during the first year after kidney, heart, liver, and pancreas transplantation, and they could be associated with certain clinical syndromes in transplant patients.

Original languageEnglish (US)
Pages (from-to)1349-1354
Number of pages6
JournalJournal of Infectious Diseases
Volume192
Issue number8
DOIs
StatePublished - Oct 15 2005

Fingerprint

Polyomavirus
Viremia
BK Virus
JC Virus
Pancreas
Transplants
Kidney
Liver
Pancreas Transplantation
Heart Transplantation
Liver Transplantation
Kidney Transplantation

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases

Cite this

A longitudinal molecular surveillance study of human polyomavirus viremia in heart, kidney, liver, and pancreas transplant patients. / PV16000 Study Group.

In: Journal of Infectious Diseases, Vol. 192, No. 8, 15.10.2005, p. 1349-1354.

Research output: Contribution to journalArticle

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abstract = "In this study of 263 heart, kidney, liver, and pancreas transplant patients, BK virus (BKV) and JC virus (JCV) DNAemia were observed most commonly in kidney and/or pancreas transplant patients (26{\%}), although they were also observed, to a lesser extent, in heart (7{\%}) and liver (4{\%}) transplant patients. The majority of episodes of polyomavirus DNAemia were subclinical, although, in some cases, BKV DNAemia was associated with kidney rejection, and JCV DNAemia was accompanied by nonspecific symptoms. Hence, BKV and JCV DNAemia are not uncommon during the first year after kidney, heart, liver, and pancreas transplantation, and they could be associated with certain clinical syndromes in transplant patients.",
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