A lipid peroxidative mechanism for posterior subcapsular cataract formation in the rabbit: A possible model for cataract formation in tapetoretinal diseases

J. D. Goosey; W. M. Tuan; C. A. Garcia

A lipid peroxidative mechanism for posterior subcapsular cataract formation in the rabbit: A possible model for cataract formation in tapetoretinal diseases

J. D. Goosey, W. M. Tuan, C. A. Garcia

Research output: Contribution to journal › Article › peer-review

Abstract

Posterior subcapsular cataracts developed in rabbits following injection of docosahexenoic acid. Autoxidation of docosahexenoic acid in rabbit vitreous was demonstrated by the formation of malondialdehyde and vitreous fluorescence. The onset of posterior subcapsular cataract formation was temporally correlated with declining levels of vitreous malondialdehyde.

Original language	English (US)
Pages (from-to)	608-612
Number of pages	5
Journal	Investigative Ophthalmology and Visual Science
Volume	25
Issue number	5
State	Published - 1984
Externally published	Yes

ASJC Scopus subject areas

Ophthalmology
Sensory Systems
Cellular and Molecular Neuroscience

Cite this

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title = "A lipid peroxidative mechanism for posterior subcapsular cataract formation in the rabbit: A possible model for cataract formation in tapetoretinal diseases",

abstract = "Posterior subcapsular cataracts developed in rabbits following injection of docosahexenoic acid. Autoxidation of docosahexenoic acid in rabbit vitreous was demonstrated by the formation of malondialdehyde and vitreous fluorescence. The onset of posterior subcapsular cataract formation was temporally correlated with declining levels of vitreous malondialdehyde.",

author = "Goosey, {J. D.} and Tuan, {W. M.} and Garcia, {C. A.}",

year = "1984",

language = "English (US)",

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pages = "608--612",

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AU - Tuan, W. M.

AU - Garcia, C. A.

PY - 1984

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AB - Posterior subcapsular cataracts developed in rabbits following injection of docosahexenoic acid. Autoxidation of docosahexenoic acid in rabbit vitreous was demonstrated by the formation of malondialdehyde and vitreous fluorescence. The onset of posterior subcapsular cataract formation was temporally correlated with declining levels of vitreous malondialdehyde.

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A lipid peroxidative mechanism for posterior subcapsular cataract formation in the rabbit: A possible model for cataract formation in tapetoretinal diseases

Abstract

ASJC Scopus subject areas

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