Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 123-129 |
| Number of pages | 7 |
| Journal | Cancer Genetics and Cytogenetics |
| Volume | 18 |
| Issue number | 2 |
| DOIs | |
| State | Published - 1985 |
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ASJC Scopus subject areas
- Cancer Research
- Genetics
- Molecular Biology
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A human c-src gene resides on the proximal long arm of chromosome 20 (cen→q131). / Sakaguchi, Alan Y; Mohandas, T.; Naylor, Susan L.
In: Cancer Genetics and Cytogenetics, Vol. 18, No. 2, 1985, p. 123-129.Research output: Contribution to journal › Article
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TY - JOUR
T1 - A human c-src gene resides on the proximal long arm of chromosome 20 (cen→q131)
AU - Sakaguchi, Alan Y
AU - Mohandas, T.
AU - Naylor, Susan L.
PY - 1985
Y1 - 1985
N2 - A molecular clone of v-src, the oncogene of Rous sarcoma virus, was used to detect and regionally localize a human c-src proto-oncogene on chromosome #20. The human c-src gene, detected as either a 28-kbp EcoRI DNA fragment or as a 15.4-kbp BglII DNA fragment, was localized to 20 cen→q131 by filter hybridization analysis of DNAs from human-rodent somatic cell hybrids. The results indicate that c-src is on the same chromosome arm as aberrations associated with myeloproliferative disease, although the possible involvement of c-src in these aberrations is unknown.
AB - A molecular clone of v-src, the oncogene of Rous sarcoma virus, was used to detect and regionally localize a human c-src proto-oncogene on chromosome #20. The human c-src gene, detected as either a 28-kbp EcoRI DNA fragment or as a 15.4-kbp BglII DNA fragment, was localized to 20 cen→q131 by filter hybridization analysis of DNAs from human-rodent somatic cell hybrids. The results indicate that c-src is on the same chromosome arm as aberrations associated with myeloproliferative disease, although the possible involvement of c-src in these aberrations is unknown.
UR - http://www.scopus.com/inward/record.url?scp=0022238246&partnerID=8YFLogxK
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U2 - 10.1016/0165-4608(85)90062-7
DO - 10.1016/0165-4608(85)90062-7
M3 - Article
C2 - 2996754
AN - SCOPUS:0022238246
VL - 18
SP - 123
EP - 129
JO - Cancer Genetics and Cytogenetics
JF - Cancer Genetics and Cytogenetics
SN - 0165-4608
IS - 2
ER -