A grading system for bone marrow cytogenetics and its use as a standard for quality control

Louis Manhoff, Nanette Clare, Marsha Hunke, Lisa Gonzalez

Research output: Contribution to journalArticlepeer-review

Abstract

A grading system has been developed to assess the quality of the results of bone marrow cytogenetic procedures. The results of 3 1 2 years use of this grading system are reported. This grading system is a satisfactory internal standard for quality control and is adaptable for use as an external standard. The use of such an internal standard will improve the performance of the cytogenetics laboratory and will validate the quality of the results of cytogenetic examination. The use of an external standard will stimulate the standardization and improvement of cytogenetic laboratory techniques and may be used to develop performance standards for accreditation of both bone marrow and other cytogenetic laboratories. Internal and external quality controls have been used in general medical laboratories for many years, and their use should be instituted by cytogenetic laboratories as well.

Original languageEnglish (US)
Pages (from-to)167-171
Number of pages5
JournalCancer Genetics and Cytogenetics
Volume9
Issue number2
DOIs
StatePublished - Jun 1983

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cancer Research

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