Abstract
Vitally important aspects of dealing with the COVID-19 pandemic include the development of effective treatments for acute illness and prevention of infection. However, severe complications including mortality occur primarily in older adults, so a long-term approach of covering all aspects of infection and disease complications in older people is equally essential in preventing the alarming morbidity and mortality. Since severe pathological consequences of SARS-CoV-2 infection are age-related, a geropathology based platform of identifying age-related anatomic and molecular lesions aligned with processes of aging will be able to identify multiple targets for combinations of anti-aging drugs. A comprehensive geropathology-driven therapeutic approach of covering complications and vaccine effectiveness by enhancing resilience to aging will therefore play a critical role in preventing the alarming medical complications of disease not only with SARS-CoV-2 but also serve as a model for successfully controlling and preventing future world-wide pandemics.
Original language | English (US) |
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Pages (from-to) | 106-108 |
Number of pages | 3 |
Journal | Aging Pathobiology and Therapeutics |
Volume | 2 |
Issue number | 2 |
DOIs |
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State | Published - 2020 |
Keywords
- COVID-19 complications
- geropathology
- Resilience to aging
- SARS-CoV-2 pathology
ASJC Scopus subject areas
- Geriatrics and Gerontology
- Cellular and Molecular Neuroscience
- Pharmacology, Toxicology and Pharmaceutics (miscellaneous)
- Drug Discovery