@article{d82d0a9881704701b7c373dc47860a52,
title = "A detailed experimental and Monte Carlo analysis of gold nanoparticle dose enhancement using 6 MV and 18 MV external beam energies in a macroscopic scale",
abstract = "Dose enhancement due to gold nanoparticles (GNPs) has been quantified experimentally and through Monte Carlo simulations for external beam radiation therapy energies of 6 and 18 MV. The highest enhancement was observed for the 18 MV beam at the highest GNP concentration tested, amounting to a DEF of 1.02. DEF is shown to increase with increasing concentration of gold and increasing energy in the megavoltage energy range. The largest difference in measured vs. simulated DEF across all data sets was 0.3%, showing good agreement.",
keywords = "Dose enhancement factor, Gold nanoparticles, Monte Carlo simulations, Radiation therapy",
author = "Tara Gray and Nema Bassiri and Shaquan David and Patel, {Devanshi Yogeshkumar} and Sotirios Stathakis and Neil Kirby and Mayer, {Kathryn M.}",
note = "Funding Information: This work received computational support from UTSA's HPC cluster SHAMU, operated by the Office of Information Technology. The authors acknowledge the University of Texas at San Antonio Kleberg Advanced Microscopy Center for support during this work. Funding Information: This work was supported in part by the San Antonio Medical Foundation (San Antonio, TX, USA) and the San Antonio Life Sciences Institute (San Antonio, TX, USA), as well as the UTSA RISE Program under National Institutes of Health (Bethesda, MD, USA) grant GM060655. This work received computational support from UTSA's HPC cluster SHAMU, operated by the Office of Information Technology. The authors acknowledge the University of Texas at San Antonio Kleberg Advanced Microscopy Center for support during this work. Funding Information: This work was supported in part by the San Antonio Medical Foundation (San Antonio, TX, USA) and the San Antonio Life Sciences Institute (San Antonio, TX, USA) , as well as the UTSA RISE Program under National Institutes of Health (Bethesda, MD, USA) grant GM060655 . Publisher Copyright: {\textcopyright} 2021 Elsevier Ltd",
year = "2021",
month = may,
doi = "10.1016/j.apradiso.2021.109638",
language = "English (US)",
volume = "171",
journal = "Applied Radiation and Isotopes",
issn = "0969-8043",
publisher = "Elsevier Limited",
}