A Dancer Caught Midstep: The Structure of ATP-Bound Hsp70

Rui Sousa

Research output: Contribution to journalShort survey

4 Scopus citations

Abstract

Hsp70 ATP binding induces substrate release, but the transiency of this state has inhibited its characterization. In this issue, Kityk et al. determine the Hsp70*ATP structure utilizing engineered disulfide bonds, providing insights into the workings of this essential molecular machine.

Original languageEnglish (US)
Pages (from-to)821-823
Number of pages3
JournalMolecular Cell
Volume48
Issue number6
DOIs
StatePublished - Dec 28 2012

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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