TY - JOUR
T1 - A critical and descriptive approach to interictal behavior with the Neurobehavior Inventory (NBI)
AU - de Oliveira, Guilherme Nogueira M.
AU - Kummer, Arthur
AU - Marchetti, Renato Luiz
AU - de Araújo Filho, Gerardo Maria
AU - Salgado, João Vinícius
AU - David, Anthony S.
AU - Teixeira, Antônio Lúcio
PY - 2012/11
Y1 - 2012/11
N2 - Purpose: The purpose of this study was to test the psychometric properties of the Neurobehavior Inventory (NBI) in a group of temporal lobe epilepsy (TLE) patients from a tertiary care center, correlating its scores with the presence of psychiatric symptoms. Methods: Clinical and sociodemographic data from ninety-six TLE outpatients were collected, and a neuropsychiatric evaluation was performed with the following instruments: Mini-Mental State Examination (MMSE), structured psychiatric interview (MINI-PLUS), Neurobehavior Inventory (NBI), and Hamilton Depression Rating Scale (HAM-D). Results: Some traits evaluated by the NBI showed adequate internal consistency (mean inter-item correlation between 0.2 and 0.4) and were frequent, such as religiosity (74%) and repetitiveness (60.4%). Principal component analysis showed three factors, named here as emotions (Factor 1), hyposexuality (Factor 2), and unusual ideas (Factor 3). Depressive symptoms on HAM-D showed a strong association with emotions and hyposexuality factors. When patients with left TLE and right TLE were compared, the former exhibited more sadness (p. =0.017), and the latter, a greater tendency toward sense of personal destiny (p. =0.028). Conclusion: Depression influences NBI scoring, mainly emotionality and hyposexuality traits. Neurobehavior Inventory subscales can be better interpreted with an appropriate evaluation of comorbid mood and anxiety disorders. Compromise in left temporal mesial structures is associated with increased tendency toward sad affect, whereas right temporal pathology is associated with increased beliefs in personal destiny.
AB - Purpose: The purpose of this study was to test the psychometric properties of the Neurobehavior Inventory (NBI) in a group of temporal lobe epilepsy (TLE) patients from a tertiary care center, correlating its scores with the presence of psychiatric symptoms. Methods: Clinical and sociodemographic data from ninety-six TLE outpatients were collected, and a neuropsychiatric evaluation was performed with the following instruments: Mini-Mental State Examination (MMSE), structured psychiatric interview (MINI-PLUS), Neurobehavior Inventory (NBI), and Hamilton Depression Rating Scale (HAM-D). Results: Some traits evaluated by the NBI showed adequate internal consistency (mean inter-item correlation between 0.2 and 0.4) and were frequent, such as religiosity (74%) and repetitiveness (60.4%). Principal component analysis showed three factors, named here as emotions (Factor 1), hyposexuality (Factor 2), and unusual ideas (Factor 3). Depressive symptoms on HAM-D showed a strong association with emotions and hyposexuality factors. When patients with left TLE and right TLE were compared, the former exhibited more sadness (p. =0.017), and the latter, a greater tendency toward sense of personal destiny (p. =0.028). Conclusion: Depression influences NBI scoring, mainly emotionality and hyposexuality traits. Neurobehavior Inventory subscales can be better interpreted with an appropriate evaluation of comorbid mood and anxiety disorders. Compromise in left temporal mesial structures is associated with increased tendency toward sad affect, whereas right temporal pathology is associated with increased beliefs in personal destiny.
KW - Depression
KW - Gastaut-Geschwind syndrome
KW - Interictal behavior
KW - Neurobehavior Inventory
KW - Psychiatric disorders
KW - Temporal lobe epilepsy
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U2 - 10.1016/j.yebeh.2012.08.031
DO - 10.1016/j.yebeh.2012.08.031
M3 - Article
C2 - 23103306
AN - SCOPUS:84868691454
SN - 1525-5050
VL - 25
SP - 334
EP - 340
JO - Epilepsy and Behavior
JF - Epilepsy and Behavior
IS - 3
ER -