A counter antigonadotrophic effect of melatonin in male rats

R. J. Reiter; D. E. Blask; Mary K. Vaughan

doi:10.1159/000122427

A counter antigonadotrophic effect of melatonin in male rats

R. J. Reiter, D. E. Blask, Mary K. Vaughan

Department of Cell Systems & Anatomy

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

Blinding and anosmia in male rats is followed by retarded bodily development, reduced weights of the gonads and adnexa, and depressed levels of pituitary luteinizing hormone and prolactin. The effects of dual sensory deprivation are negated, for the most part, by either pinealectomy or the weekly subcutaneous implantation of melatonin (in beeswax). This is the first report that melatonin negates the antigonadotrophic influence of the rat pineal gland.

Original language	English (US)
Pages (from-to)	72-80
Number of pages	9
Journal	Neuroendocrinology
Volume	19
Issue number	1
DOIs	https://doi.org/10.1159/000122427
State	Published - 1975

Keywords

Anosmia
Blinding
Luteinizing hormone
Melatonin
Pineal gland
Prolactin
Rat

ASJC Scopus subject areas

Endocrine and Autonomic Systems
Endocrinology
Cellular and Molecular Neuroscience
Endocrinology, Diabetes and Metabolism

Access to Document

10.1159/000122427

Cite this

@article{258a5072f6c84375b5904a71b4aebd31,

title = "A counter antigonadotrophic effect of melatonin in male rats",

abstract = "Blinding and anosmia in male rats is followed by retarded bodily development, reduced weights of the gonads and adnexa, and depressed levels of pituitary luteinizing hormone and prolactin. The effects of dual sensory deprivation are negated, for the most part, by either pinealectomy or the weekly subcutaneous implantation of melatonin (in beeswax). This is the first report that melatonin negates the antigonadotrophic influence of the rat pineal gland.",

keywords = "Anosmia, Blinding, Luteinizing hormone, Melatonin, Pineal gland, Prolactin, Rat",

author = "Reiter, {R. J.} and Blask, {D. E.} and Vaughan, {Mary K.}",

year = "1975",

doi = "10.1159/000122427",

language = "English (US)",

volume = "19",

pages = "72--80",

journal = "Neuroendocrinology",

issn = "0028-3835",

publisher = "S. Karger AG",

number = "1",

}

TY - JOUR

T1 - A counter antigonadotrophic effect of melatonin in male rats

AU - Reiter, R. J.

AU - Blask, D. E.

AU - Vaughan, Mary K.

PY - 1975

Y1 - 1975

N2 - Blinding and anosmia in male rats is followed by retarded bodily development, reduced weights of the gonads and adnexa, and depressed levels of pituitary luteinizing hormone and prolactin. The effects of dual sensory deprivation are negated, for the most part, by either pinealectomy or the weekly subcutaneous implantation of melatonin (in beeswax). This is the first report that melatonin negates the antigonadotrophic influence of the rat pineal gland.

AB - Blinding and anosmia in male rats is followed by retarded bodily development, reduced weights of the gonads and adnexa, and depressed levels of pituitary luteinizing hormone and prolactin. The effects of dual sensory deprivation are negated, for the most part, by either pinealectomy or the weekly subcutaneous implantation of melatonin (in beeswax). This is the first report that melatonin negates the antigonadotrophic influence of the rat pineal gland.

KW - Anosmia

KW - Blinding

KW - Luteinizing hormone

KW - Melatonin

KW - Pineal gland

KW - Prolactin

KW - Rat

UR - http://www.scopus.com/inward/record.url?scp=0016653286&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0016653286&partnerID=8YFLogxK

U2 - 10.1159/000122427

DO - 10.1159/000122427

M3 - Article

C2 - 1207873

AN - SCOPUS:0016653286

SN - 0028-3835

VL - 19

SP - 72

EP - 80

JO - Neuroendocrinology

JF - Neuroendocrinology

IS - 1

ER -

A counter antigonadotrophic effect of melatonin in male rats

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this