A continuously monitored recirculating perfusion system for measuring intestinal absorption

Richard P. Spencer; Tapan K. Chaudhuri; Tuhin K. Chaudhuri; Teodoro Herskovic

doi:10.1007/BF02239513

A continuously monitored recirculating perfusion system for measuring intestinal absorption

Richard P. Spencer
, Tapan K. Chaudhuri
, Tuhin K. Chaudhuri
, Teodoro Herskovic

Research output: Contribution to journal › Article › peer-review

Abstract

A system was developed for the continuous and simultaneous measurement of water and nutrient (or electrolyte) absorption from the intestine. A recirculating loop (with a reservoir) was kept moving by means of two peristaltic pumps. Water was quantitated by means of a chromogenic nonabsorbed marker and a spectrophotometer. The nutrient (or electrolyte) was present in radiolabeled form and was quantitated by means of a gamma-ray detector. Use of the system was illustrated by the study of²²NaCl and⁷⁵Se-l-selenomethionine. By utilization of a suitable detector, beta-emitting radionuclides may also be used in the perfusing fluid.

Original language	English (US)
Pages (from-to)	61-66
Number of pages	6
Journal	The American Journal of Digestive Diseases
Volume	14
Issue number	1
DOIs	https://doi.org/10.1007/BF02239513
State	Published - Jan 1969
Externally published	Yes

ASJC Scopus subject areas

Gastroenterology

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10.1007/BF02239513

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year = "1969",

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AU - Chaudhuri, Tuhin K.

AU - Herskovic, Teodoro

PY - 1969/1

Y1 - 1969/1

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AB - A system was developed for the continuous and simultaneous measurement of water and nutrient (or electrolyte) absorption from the intestine. A recirculating loop (with a reservoir) was kept moving by means of two peristaltic pumps. Water was quantitated by means of a chromogenic nonabsorbed marker and a spectrophotometer. The nutrient (or electrolyte) was present in radiolabeled form and was quantitated by means of a gamma-ray detector. Use of the system was illustrated by the study of22NaCl and75Se-l-selenomethionine. By utilization of a suitable detector, beta-emitting radionuclides may also be used in the perfusing fluid.

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A continuously monitored recirculating perfusion system for measuring intestinal absorption

Abstract

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