A continuously monitored recirculating perfusion system for measuring intestinal absorption

Richard P. Spencer, Tapan K. Chaudhuri, Tuhin K. Chaudhuri, Teodoro Herskovic

Research output: Contribution to journalArticle

Abstract

A system was developed for the continuous and simultaneous measurement of water and nutrient (or electrolyte) absorption from the intestine. A recirculating loop (with a reservoir) was kept moving by means of two peristaltic pumps. Water was quantitated by means of a chromogenic nonabsorbed marker and a spectrophotometer. The nutrient (or electrolyte) was present in radiolabeled form and was quantitated by means of a gamma-ray detector. Use of the system was illustrated by the study of22NaCl and75Se-l-selenomethionine. By utilization of a suitable detector, beta-emitting radionuclides may also be used in the perfusing fluid.

Original languageEnglish (US)
Pages (from-to)61-66
Number of pages6
JournalThe American Journal of Digestive Diseases
Volume14
Issue number1
DOIs
StatePublished - Jan 1 1969
Externally publishedYes

ASJC Scopus subject areas

  • Gastroenterology

Fingerprint Dive into the research topics of 'A continuously monitored recirculating perfusion system for measuring intestinal absorption'. Together they form a unique fingerprint.

  • Cite this