A Community-transmitted Case of Severe Acute Respiratory Distress Syndrome (SARS) Due to SARS-CoV-2 in the United States

Bradley Sanville, Rebecca Corbett, Wesley Pidcock, Kaitlyn Hardin, Christian Sebat, Minh Vu Nguyen, George R. Thompson, Angela Haczku, Michael Schivo, Stuart Cohen

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

This is the first known community transmission case of the novel coronavirus disease (COVID-19) in the United States, with significant public health implications. Diagnosis of COVID-19 is currently confirmed with PCR based testing of appropriate respiratory samples. Given the absence of travel or known exposure history, this patient did not meet the criteria for testing according to CDC guidelines at the time of her presentation. Since this case, any patient with severe disease (eg, ARDS or pneumonia) requiring hospitalization without an explanatory diagnosis can be tested even if no clear source of exposure is identified. While influencing national health policies for revising screening criteria, this case also highlighted significant knowledge gaps in diagnosis and treatment and a desperate need for early, widespread, fast and cheap testing for COVID-19.

Original languageEnglish (US)
Pages (from-to)2222-2226
Number of pages5
JournalClinical Infectious Diseases
Volume71
Issue number16
DOIs
StatePublished - Oct 15 2020
Externally publishedYes

Keywords

  • COVID-19
  • SARS-CoV-2
  • community transmission
  • index case
  • novel coronavirus

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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