A clinical and microbiologic analysis of risk factors for puerperal endometritis

E. R. Newton, T. J. Prihoda, R. S. Gibbs

Research output: Contribution to journalArticle

92 Citations (Scopus)

Abstract

Predictors of postpartum endometritis were identified in 607 asymptomatic, laboring women. One hundred (16.5%) developed postpartum endometritis. Multivariate analysis using stepwise logistic regression identified cesarean delivery (relative risk 12.8; P<.0001) as the dominant overall predictor. In patients with cesarean delivery (N = 124), prophylactic antibiotics (relative risk 0.54; P<.0002) and high-virulence bacteria or Mycoplasma hominis (relative risk 1.4; P<.01) predicted the incidence of endometritis, and in patients with vaginal delivery (N = 483), 'bacterial vaginosis organisms' (relative risk 14.2; P<.001) and aerobic gram-negative rods (relative risk 4.2; P<.01) predicted endometritis. Despite significant associations found on univariate analysis, clinical variables such as duration of labor, rupture of membranes, and internal monitoring were not predictive of endometritis in the multivariate analysis. Our findings show that cesarean delivery and certain organisms, such as bacterial vaginosis or high-virulence organisms, predict endometritis, and that clinical variables may be facilitators rather than predictors of endometritis.

Original languageEnglish (US)
Pages (from-to)402-406
Number of pages5
JournalObstetrics and Gynecology
Volume75
Issue number3 I
StatePublished - 1990

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Endometritis
Bacterial Vaginosis
Postpartum Period
Virulence
Multivariate Analysis
Mycoplasma hominis
Rupture
Logistic Models
Anti-Bacterial Agents
Bacteria
Membranes
Incidence

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Newton, E. R., Prihoda, T. J., & Gibbs, R. S. (1990). A clinical and microbiologic analysis of risk factors for puerperal endometritis. Obstetrics and Gynecology, 75(3 I), 402-406.

A clinical and microbiologic analysis of risk factors for puerperal endometritis. / Newton, E. R.; Prihoda, T. J.; Gibbs, R. S.

In: Obstetrics and Gynecology, Vol. 75, No. 3 I, 1990, p. 402-406.

Research output: Contribution to journalArticle

Newton, ER, Prihoda, TJ & Gibbs, RS 1990, 'A clinical and microbiologic analysis of risk factors for puerperal endometritis', Obstetrics and Gynecology, vol. 75, no. 3 I, pp. 402-406.
Newton, E. R. ; Prihoda, T. J. ; Gibbs, R. S. / A clinical and microbiologic analysis of risk factors for puerperal endometritis. In: Obstetrics and Gynecology. 1990 ; Vol. 75, No. 3 I. pp. 402-406.
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