A bipolar method for selective activation of nerve fibers using biphasic rectangular pulses

Biphasic selective stimulation is an effective electrical stimulation mode for preventing nerve fibers against electrochemical damage, and for smooth muscle contraction and decrease of muscle fatigue. Here a bipolar method was presented using biphasic rectangular pulses to achieve selective excitation of nerve fibers. The computer model simulation proved that it could selectively and effectively activation nerve fibers. And the feasibility of this method was verified by animal experiments on toad sciatic nerve trunks in vitro. It was also successfully explained in theory by use of the concept of "activating function".