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• 2021

  Comparison of rectal swab, glove tip, and participant-collected stool techniques for gut microbiome sampling

  Short, M. I., Hudson, R., Besasie, B. D., Reveles, K. R., Shah, D. P., Nicholson, S., Johnson-Pais, T. L., Weldon, K., Lai, Z., Leach, R. J., Fongang, B. & Liss, M. A., Dec 2021, In: BMC Microbiology. 21, 1, 26.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Gastrointestinal Microbiome
  • Microbiota
  • Prostatic Neoplasms
  • Discriminant Analysis
  • Gold
• 2020

  A copy number gain on 18q present in primary prostate tumors is associated with metastatic outcome

  Ashcraft, K. A., Johnson-Pais, T. L., Troyer, D. A., Hernandez, J. & Leach, R. J., Dec 2020, In: Urologic Oncology: Seminars and Original Investigations. 38, 12, p. 932.e1-932.e7

  Research output: Contribution to journal › Article › peer-review

  • Prostate
  • Neoplasms
  • Prostatectomy
  • Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein
  • Immunohistochemistry

• A genome-wide association study of prostate cancer in Latinos

  Du, Z., Hopp, H., Ingles, S. A., Huff, C., Sheng, X., Weaver, B., Stern, M., Hoffmann, T. J., John, E. M., Van Den Eeden, S. K., Strom, S., Leach, R. J., Thompson, I. M., Witte, J. S., Conti, D. V. & Haiman, C. A., Apr 1 2020, In: International Journal of Cancer. 146, 7, p. 1819-1826 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Genome-Wide Association Study
  • Hispanic Americans
  • Prostatic Neoplasms
  • Population
  • Genome
  8 Scopus citations

• A Germline Variant at 8q24 Contributes to Familial Clustering of Prostate Cancer in Men of African Ancestry

  Darst, B. F., Wan, P., Sheng, X., Bensen, J. T., Ingles, S. A., Rybicki, B. A., Nemesure, B., John, E. M., Fowke, J. H., Stevens, V. L., Berndt, S. I., Huff, C. D., Strom, S. S., Park, J. Y., Zheng, W., Ostrander, E. A., Walsh, P. C., Srivastava, S., Carpten, J., Sellers, T. A. & 52 others, Yamoah, K., Murphy, A. B., Sanderson, M., Crawford, D. C., Gapstur, S. M., Bush, W. S., Aldrich, M. C., Cussenot, O., Yeager, M., Petrovics, G., Cullen, J., Neslund-Dudas, C., Kittles, R. A., Xu, J., Stern, M. C., Kote-Jarai, Z., Govindasami, K., Chokkalingam, A. P., Multigner, L., Parent, M. E., Menegaux, F., Cancel-Tassin, G., Kibel, A. S., Klein, E. A., Goodman, P. J., Drake, B. F., Hu, J. J., Clark, P. E., Blanchet, P., Casey, G., Hennis, A. J. M., Lubwama, A., Thompson, I. M., Leach, R., Gundell, S. M., Pooler, L., Xia, L., Mohler, J. L., Fontham, E. T. H., Smith, G. J., Taylor, J. A., Eeles, R. A., Brureau, L., Chanock, S. J., Watya, S., Stanford, J. L., Mandal, D., Isaacs, W. B., Cooney, K., Blot, W. J., Conti, D. V. & Haiman, C. A., Sep 2020, In: European Urology. 78, 3, p. 316-320 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Familial Prostate cancer
  • Cluster Analysis
  • Prostatic Neoplasms
  • Heterozygote
  • Confidence Intervals
  4 Scopus citations

• Lessons Learned from the Medical University of South Carolina Transdisciplinary Collaborative Center (TCC) in Precision Medicine and Minority Men’s Health

  Halbert, C. H., Allen, C. G., Jefferson, M., Magwood, G. S., Melvin, C., Babatunde, O. A., Baquet, C., Delmoor, E., Johnson, J., Mathews, D., Leach, R. J. & Ricks-Santi, L., 2020, In: American Journal of Men's Health. 14, 6

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Minority Health
  • Men's Health
  • Precision Medicine
  • transdisciplinary
  • medicine

• Targeted Mass Spectrometry of a Clinically Relevant PSA Variant from Post-DRE Urines for Quantitation and Genotype Determination

  Otto, J. J., Correll, V. L., Engstroem, H. A., Hitefield, N. L., Main, B. P., Albracht, B., Johnson-Pais, T., Yang, L. F., Liss, M., Boutros, P. C., Kislinger, T., Leach, R. J., Semmes, O. J. & Nyalwidhe, J. O., Nov 2020, In: Proteomics - Clinical Applications. 14, 6, 2000012.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mass spectrometry
  • Prostate-Specific Antigen
  • Mass Spectrometry
  • Polymorphism
  • Genotype
• 2019

  Higher baseline dietary fat and fatty acid intake is associated with increased risk of incident prostate cancer in the SABOR study

  Liss, M. A., Al-Bayati, O., Gelfond, J., Goros, M., Ullevig, S., DiGiovanni, J., Hamilton-Reeves, J., O’Keefe, D., Bacich, D., Weaver, B., Leach, R. & Thompson, I. M., May 1 2019, In: Prostate Cancer and Prostatic Diseases. 22, 2, p. 244-251 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Dietary Fats
  • Fatty Acids
  • Prostatic Neoplasms
  • Biomarkers
  • Nutrients
  9 Scopus citations

• Incorporation of Urinary Prostate Cancer Antigen 3 and TMPRSS2:ERG into Prostate Cancer Prevention Trial Risk Calculator

  Ankerst, D. P., Goros, M., Tomlins, S. A., Patil, D., Feng, Z., Wei, J. T., Sanda, M. G., Gelfond, J., Thompson, I. M., Leach, R. J. & Liss, M. A., Jan 2019, In: European Urology Focus. 5, 1, p. 54-61 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Prostatic Neoplasms
  • Antigens
  • Biopsy
  • Calibration
  • Bayes Theorem
  4 Scopus citations

• Microbiome diversity in carriers of fluoroquinolone resistant escherichia coli

  Liss, M. A., Leach, R. J., Rourke, E., Sherrill, A., Johnson-Pais, T., Lai, Z., Basler, J. & White, J. R., Mar 2019, In: Investigative and Clinical Urology. 60, 2, p. 75-83 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Fluoroquinolones
  • Microbiota
  • Escherichia coli
  • Enterobacteriaceae
  • Biopsy
  2 Scopus citations

• Multi-cohort modeling strategies for scalable globally accessible prostate cancer risk tools

  Tolksdorf, J., Kattan, M. W., Boorjian, S. A., Freedland, S. J., Saba, K., Poyet, C., Guerrios, L., De Hoedt, A., Liss, M. A., Leach, R. J., Hernandez, J., Vertosick, E., Vickers, A. J. & Ankerst, D. P., 2019, In: BMC Medical Research Methodology. 19, 1, 191.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Prostatic Neoplasms
  • Biopsy
  • Prostate
  • Area Under Curve
  • Statistics

• Vortioxetine reverses medial prefrontal cortex-mediated cognitive deficits in male rats induced by castration as a model of androgen deprivation therapy for prostate cancer

  Sharp, A. M., Lertphinyowong, S., Yee, S. S., Paredes, D., Gelfond, J., Johnson-Pais, T. L., Leach, R. J., Liss, M., Risinger, A. L., Sullivan, A. C., Thompson, I. M. & Morilak, D. A., Nov 1 2019, In: Psychopharmacology. 236, 11, p. 3183-3195 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Vortioxetine
  • Castration
  • Androgens
  • Prefrontal Cortex
  • Prostatic Neoplasms
  2 Scopus citations
• 2018

  A Contemporary Prostate Biopsy Risk Calculator Based on Multiple Heterogeneous Cohorts

  Ankerst, D. P., Straubinger, J., Selig, K., Guerrios, L., De Hoedt, A., Hernandez, J., Liss, M. A., Leach, R. J., Freedland, S. J., Kattan, M. W., Nam, R., Haese, A., Montorsi, F., Boorjian, S. A., Cooperberg, M. R., Poyet, C., Vertosick, E. & Vickers, A. J., Aug 2018, In: European Urology. 74, 2, p. 197-203 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Prostate
  • Biopsy
  • Prostatic Neoplasms
  21 Scopus citations

• Adipose Tissue-Secreted Factors Alter Bladder Cancer Cell Migration

  Hariharan, N., Ashcraft, K. A., Svatek, R. S., Livi, C. B., Wilson, D., Kaushik, D., Leach, R. J. & Johnson-Pais, T. L., 2018, In: Journal of Obesity. 2018, 9247864.

  Research output: Contribution to journal › Article › peer-review

  • Thromboplastin
  • Conditioned Culture Medium
  • Urinary Bladder Neoplasms
  • Stromal Cells
  • Adipose Tissue
  5 Scopus citations

• Boolean analysis identifies CD38 as a biomarker of aggressive localized prostate cancer

  Sahoo, D., Wei, W., Auman, H., Hurtado-Coll, A., Carroll, P. R., Fazli, L., Gleave, M. E., Lin, D. W., Nelson, P. S., Simko, J., Thompson, I. M., Leach, R. J., Troyer, D. A., True, L. D., McKenney, J. K., Feng, Z. & Brooks, J. D., 2018, In: Oncotarget. 9, 5, p. 6550-6561 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Prostatic Neoplasms
  • Biomarkers
  • Canaries
  • Prostate-Specific Antigen
  • Survival
  8 Scopus citations

• Circadian genes and risk of prostate cancer in the prostate cancer prevention trial

  Chu, L. W., Till, C., Yang, B., Tangen, C. M., Goodman, P. J., Yu, K., Zhu, Y., Han, S., Hoque, A. M., Ambrosone, C., Thompson, I., Leach, R. & Hsing, A. W., Mar 2018, In: Molecular Carcinogenesis. 57, 3, p. 462-466 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Prostatic Neoplasms
  • Finasteride
  • Genes
  • Placebos
  • Biopsy
  5 Scopus citations

• Metabolic Biosynthesis Pathways Identified from Fecal Microbiome Associated with Prostate Cancer

  Liss, M. A., White, J. R., Goros, M., Gelfond, J., Leach, R., Johnson-Pais, T., Lai, Z., Rourke, E., Basler, J., Ankerst, D. & Shah, D. P., Nov 2018, In: European Urology. 74, 5, p. 575-582 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Microbiota
  • Metabolic Networks and Pathways
  • Prostatic Neoplasms
  • Prostate
  • Folic Acid
  27 Scopus citations

• The effect of 3-month finasteride challenge on biomarkers for predicting cancer outcome on biopsy: Results of a randomized trial

  Hernandez, J., Gelfond, J., Goros, M., Liss, M. A., Liang, Y., Ankerst, D., Thompson, I. M. & Leach, R. J., Oct 2018, In: PloS one. 13, 10, e0204823.

  Research output: Contribution to journal › Article › peer-review

  • Finasteride
  • Biopsy
  • prostatic neoplasms
  • biopsy
  • Tumor Biomarkers
  1 Scopus citations
• 2017

  Association between variants in genes involved in the immune response and prostate cancer risk in men randomized to the finasteride arm in the Prostate Cancer Prevention Trial

  Winchester, D. A., Till, C., Goodman, P. J., Tangen, C. M., Santella, R. M., Johnson-Pais, T. L., Leach, R. J., Xu, J., Zheng, S. L., Thompson, I. M., Lucia, M. S., Lippman, S. M., Parnes, H. L., Isaacs, W. B., De Marzo, A. M., Drake, C. G. & Platz, E. A., Jun 1 2017, In: Prostate. 77, 8, p. 908-919 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Finasteride
  • Prostatic Neoplasms
  • Interleukin-10
  • Odds Ratio
  • Confidence Intervals
  11 Scopus citations

• Helicobacter Pylori Infection in Texas Hispanic and Non-Hispanic White Men: Implications for Gastric Cancer Risk Disparities

  Long Parma, D., Muñoz, E., Ogden, S. M., Westin, G. F., Leach, R. J., Thompson, I. M. & Ramirez, A. G., Jul 1 2017, In: American Journal of Men's Health. 11, 4, p. 1039-1045 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Helicobacter Infections
  • Helicobacter pylori
  • Hispanic Americans
  • European Continental Ancestry Group
  • cancer
  5 Scopus citations

• Multiplexed targeted mass spectrometry assays for prostate cancer-associated urinary proteins

  Shi, T., Quek, S. I., Gao, Y., Nicora, C. D., Nie, S., Fillmore, T. L., Liu, T., Rodland, K. D., Smith, R. D., Leach, R. J., Thompson, I. M., Vitello, E. A., Ellis, W. J., Liu, A. Y. & Qian, W. J., 2017, In: Oncotarget. 8, 60, p. 101887-101898 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Mass Spectrometry
  • Prostatic Neoplasms
  • Urine
  • Proteins
  • Biomarkers
  5 Scopus citations
• 2016

  Adding genetic risk score to family history identifies twice as many high-risk men for prostate cancer: Results from the prostate cancer prevention trial

  Chen, H., Liu, X., Brendler, C. B., Ankerst, D. P., Leach, R. J., Goodman, P. J., Lucia, M. S., Tangen, C. M., Wang, L., Hsu, F. C., Sun, J., Kader, A. K., Isaacs, W. B., Helfand, B. T., Zheng, S. L., Thompson, I. M., Platz, E. A. & Xu, J., Sep 1 2016, In: Prostate. 76, 12, p. 1120-1129 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Prostatic Neoplasms
  • Single Nucleotide Polymorphism
  • Neoplasm Grading
  • Genetic Predisposition to Disease
  • Early Detection of Cancer
  31 Scopus citations

• Association of androgen metabolism gene polymorphisms with prostate cancer risk and androgen concentrations: Results from the prostate cancer prevention trial

  Price, D. K., Chau, C. H., Till, C., Goodman, P. J., Leach, R. J., Johnson-Pais, T. L., Hsing, A. W., Hoque, A., Parnes, H. L., Schenk, J. M., Tangen, C. M., Thompson, I. M., Reichardt, J. K. V. & Figg, W. D., Aug 2016, In: Cancer. 122, 15, p. 2332-2340 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Androgens
  • Prostatic Neoplasms
  • Single Nucleotide Polymorphism
  • Oxidoreductases
  • Steroids
  12 Scopus citations

• Key genes involved in the immune response are generally not associated with intraprostatic inflammation in men without a prostate cancer diagnosis: Results from the prostate cancer prevention trial

  Winchester, D. A., Gurel, B., Till, C., Goodman, P. J., Tangen, C. M., Santella, R. M., Johnson-Pais, T. L., Leach, R. J., Thompson, I. M., Xu, J., Zheng, S. L., Lucia, M. S., Lippman, S. M., Parnes, H. L., Isaacs, W. B., Drake, C. G., De Marzo, A. M. & Platz, E. A., May 1 2016, In: Prostate. 76, 6, p. 565-574 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Prostatic Neoplasms
  • Inflammation
  • Single Nucleotide Polymorphism
  • Alleles
  • Genes
  5 Scopus citations

• MBDDiff: An R package designed specifically for processing MBDcap-seq datasets

  Liu, Y., Wilson, D., Leach, R. J. & Chen, Y., Aug 18 2016, In: BMC genomics. 17, 432.

  Research output: Contribution to journal › Article › peer-review

  • Noise
  • Datasets
  • DNA Methylation
  • Methylation
  • Biological Phenomena
  2 Scopus citations

• Roles of distal and genic methylation in the development of prostate tumorigenesis revealed by genome-wide DNA methylation analysis

  Wang, Y., Jadhav, R. R., Liu, J., Wilson, D., Chen, Y., Thompson, I. M., Troyer, D. A., Hernandez, J., Shi, H., Leach, R. J., Huang, T. H. M. & Jin, V. X., 2016, In: Scientific reports. 6, 22051.

  Research output: Contribution to journal › Article › peer-review

  • DNA Methylation
  • Methylation
  • Prostate
  • Carcinogenesis
  • Genome
  13 Scopus citations

• Serial Percent Free Prostate Specific Antigen in Combination with Prostate Specific Antigen for Population Based Early Detection of Prostate Cancer

  Ankerst, D. P., Gelfond, J., Goros, M., Herrera, J., Strobl, A., Thompson, I. M., Hernandez, J. & Leach, R. J., Aug 1 2016, In: Journal of Urology. 196, 2, p. 355-360 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Prostate-Specific Antigen
  • Early Detection of Cancer
  • Prostatic Neoplasms
  • Population
  • Biopsy
  17 Scopus citations
• 2015

  A case control study of sarcosine as an early prostate cancer detection biomarker Urological oncology

  Ankerst, D. P., Liss, M., Zapata, D., Hoefler, J., Thompson, I. M. & Leach, R. J., Oct 1 2015, In: BMC Urology. 15, 1, 99.

  Research output: Contribution to journal › Article › peer-review

  • Sarcosine
  • Tumor Biomarkers
  • Case-Control Studies
  • Prostatic Neoplasms
  • Prostate-Specific Antigen
  12 Scopus citations

• Active surveillance is an appropriate management strategy for a proportion of men diagnosed with prostate cancer by prostate specific antigen testing

  Thompson, I. M., Overholser, S., Nielsen, M., Torkko, K., Cwilka, D., Weaver, B., Shi, X., Leach, R. J., Hernandez, J., Huang, T. & Thompson, I. M., Sep 1 2015, In: Journal of Urology. 194, 3, p. 680-684 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Prostate-Specific Antigen
  • Prostatectomy
  • Prostatic Neoplasms
  • Neoplasms
  • Biopsy
  15 Scopus citations

• A simple-to-use method incorporating genomic markers into prostate cancer risk prediction tools facilitated future validation

  Grill, S., Fallah, M., Leach, R. J., Thompson, I. M., Hemminki, K. & Ankerst, D. P., May 1 2015, In: Journal of Clinical Epidemiology. 68, 5, p. 563-573 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Single Nucleotide Polymorphism
  • Prostatic Neoplasms
  • Alleles
  • Meta-Analysis
  • Linkage Disequilibrium
  5 Scopus citations

• DNA methylation screening of primary prostate tumors identifies SRD5A2 and CYP11A1 as candidate markers for assessing risk of biochemical recurrence

  Horning, A. M., Awe, J. A., Wang, C. M., Liu, J., Lai, Z., Wang, V. Y., Jadhav, R. R., Louie, A. D., Lin, C. L., Kroczak, T., Chen, Y., Jin, V. X., Abboud-Werner, S. L., Leach, R. J., Hernandez, J., Thompson, I. M., Saranchuk, J., Drachenberg, D., Chen, C. L., Mai, S. & 1 others, Huang, T. H. M., Nov 1 2015, In: Prostate. 75, 15, p. 1790-1801 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Cholesterol Side-Chain Cleavage Enzyme
  • DNA Methylation
  • Cell-Free Nucleic Acids
  • Prostate
  • Prostatectomy
  12 Scopus citations

• Enhancement of performance in porous bead-based microchip sensors: Effects of chip geometry on bio-agent capture

  Kulla, E., Chou, J., Simmons, G. W., Wong, J., McRae, M. P., Patel, R., Floriano, P. N., Christodoulides, N., Leach, R. J., Thompson, I. M. & McDevitt, J. T., 2015, In: RSC Advances. 5, 60, p. 48194-48206 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Containers
  • Biomarkers
  • Assays
  • Geometry
  • Antigens
  2 Scopus citations

• Finasteride concentrations and prostate cancer risk: Results from the prostate cancer prevention trial

  Chau, C. H., Price, D. K., Till, C., Goodman, P. J., Chen, X., Leach, R. J., Johnson-Pais, T. L., Hsing, A. W., Hoque, A., Tangen, C. M., Chu, L., Parnes, H. L., Schenk, J. M., Reichardt, J. K. V., Thompson, I. M. & Figg, W. D., May 1 2015, In: PloS one. 10, 5, e0126672.

  Research output: Contribution to journal › Article › peer-review

  • Finasteride
  • prostatic neoplasms
  • Prostatic Neoplasms
  • Metabolism
  • Genes
  21 Scopus citations

• Identification of circadian gene variants in bipolar disorder in Latino populations

  Gonzalez, R., Gonzalez, S., Villa, E., Ramirez, M., Zavala, J., Armas, R., Contreras, J., Dassori, A., Leach, R. J., Flores, D., Jerez, A., Raventós, H., Ontiveros, A., Nicolini, H. & Escamilla, M., Aug 17 2015, In: Journal of Affective Disorders. 186, p. 367-375 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Bipolar Disorder
  • Hispanic Americans
  • Single Nucleotide Polymorphism
  • Genes
  • Population
  17 Scopus citations

• Improving patient prostate cancer risk assessment: Moving from static, globally-applied to dynamic, practice-specific risk calculators

  Strobl, A. N., Vickers, A. J., Van Calster, B., Steyerberg, E., Leach, R. J., Thompson, I. M. & Ankerst, D. P., Aug 1 2015, In: Journal of Biomedical Informatics. 56, p. 87-93 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Risk assessment
  • Risk Assessment
  • Prostatic Neoplasms
  • Forests
  • Austria
  15 Scopus citations

• Incorporation of detailed family history from the Swedish family cancer database into the PCPT risk calculator

  Grill, S., Fallah, M., Leach, R. J., Thompson, I. M., Freedland, S., Hemminki, K. & Ankerst, D. P., Feb 1 2015, In: Journal of Urology. 193, 2, p. 460-465 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Databases
  • Prostatic Neoplasms
  • Neoplasms
  • Risk Assessment
  • Decision Making
  16 Scopus citations

• Intermediate-term risk of prostate cancer is directly related to baseline prostate specific antigen: Implications for reducing the burden of prostate specific antigen screening

  Gelfond, J., Choate, K., Ankerst, D. P., Hernandez, J., Leach, R. J. & Thompson, I. M., 2015, In: Journal of Urology. 194, 1, p. 46-51 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Prostate-Specific Antigen
  • Prostatic Neoplasms
  • Neoplasms
  • Costs and Cost Analysis
  • Mortality
  12 Scopus citations

• Model-based and context-specific background correction and differential methylation testing for MBDCap-seq

  Liu, Y., Wilson, D., Leach, R. J. & Chen, Y., Dec 16 2015, Proceedings - 2015 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2015. Schapranow, L. M., Zhou, J., Hu, X. T., Ma, B., Rajasekaran, S., Miyano, S., Yoo, I., Pierce, B., Shehu, A., Gombar, V. K., Chen, B., Pai, V. & Huan, J. (eds.). Institute of Electrical and Electronics Engineers Inc., p. 214-219 6 p. 7359683. (Proceedings - 2015 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2015).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • DNA Methylation
  • Methylation
  • Genetic Promoter Regions
  • Datasets
  • Genes

• Processing of voided urine for prostate cancer RNA biomarker analysis

  Quek, S. I., Wong, O. M., Chen, A., Borges, G. T., Ellis, W. J., Salvanha, D. M., Vêncio, R. Z. N., Weaver, B., Ench, Y. M., Leach, R. J., Thompson, I. M. & Liu, A. Y., Dec 1 2015, In: Prostate. 75, 16, p. 1886-1895 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Tumor Biomarkers
  • Prostatic Neoplasms
  • Urine
  • RNA
  • Prostate
  7 Scopus citations

• Variation in genes involved in the immune response and prostate cancer risk in the placebo arm of the Prostate Cancer Prevention Trial

  Winchester, D. A., Till, C., Goodman, P. J., Tangen, C. M., Santella, R. M., Johnson-Pais, T. L., Leach, R. J., Xu, J., Zheng, S. L., Thompson, I. M., Lucia, M. S., Lippmann, S. M., Parnes, H. L., Dluzniewski, P. J., Isaacs, W. B., De Marzo, A. M., Drake, C. G. & Platz, E. A., Sep 1 2015, In: Prostate. 75, 13, p. 1403-1418 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Prostatic Neoplasms
  • Placebos
  • Odds Ratio
  • Confidence Intervals
  • Genes
  23 Scopus citations
• 2014

  Androgen receptor CAG repeat length and TMPRSS2:ETS prostate cancer risk: Results from the prostate cancer prevention trial

  Figg, W. D., Chau, C. H., Price, D. K., Till, C., Goodman, P. J., Cho, Y., Varella-Garcia, M., Reichardt, J. K. V., Tangen, C. M., Leach, R. J., Van Bokhoven, A., Thompson, I. M. & Lucia, M. S., 2014, In: Urology. 84, 1, p. 127-131 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Androgen Receptors
  • Prostatic Neoplasms
  • Odds Ratio
  • Confidence Intervals
  • Gene Fusion
  6 Scopus citations

• Focusing PSA testing on detection of high-risk prostate cancers by incorporating patient preferences into decision making

  Thompson, I. M., Leach, R. J. & Ankerst, D. P., Sep 10 2014, In: JAMA - Journal of the American Medical Association. 312, 10, p. 995-996 2 p.

  Research output: Contribution to journal › Short survey › peer-review
  25 Scopus citations

• Global signaling effects of a schizophrenia-associated missense mutation in neuregulin 1: An exploratory study using whole genome and novel kinome approaches

  Marballi, K. K., McCullumsmith, R. E., Yates, S., Escamilla, M. A., Leach, R. J., Raventos, H. & Walss-Bass, C., May 2014, In: Journal of Neural Transmission. 121, 5, p. 479-490 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuregulin-1
  • Missense Mutation
  • Schizophrenia
  • Genome
  • Peptides
  2 Scopus citations

• Prostate cancer prevention trial risk calculator 2.0 for the prediction of low- vs high-grade prostate cancer

  Ankerst, D. P., Hoefler, J., Bock, S., Goodman, P. J., Vickers, A., Hernandez, J., Sokoll, L. J., Sanda, M. G., Wei, J. T., Leach, R. J. & Thompson, I. M., Jun 2014, In: Urology. 83, 6, p. 1362-1368 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Prostate-Specific Antigen
  • Prostatic Neoplasms
  • Biopsy
  • Digital Rectal Examination
  • Logistic Models
  131 Scopus citations

• The diagnostic value of adiponectin multimers in healthy men undergoing screening for prostate cancer

  Medina, E. A., Shi, X., Grayson, M. H., Ankerst, D. P., Livi, C. B., Medina, M. V., Thompson, I. M. & Leach, R. J., Feb 2014, In: Cancer Epidemiology Biomarkers and Prevention. 23, 2, p. 309-315 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Adiponectin
  • Prostatic Neoplasms
  • Body Mass Index
  • Neoplasm Grading
  • Prostatectomy
  10 Scopus citations

• Validation of copy number variants associated with prostate cancer risk and prognosis

  Blackburn, A., Wilson, D., Gelfond, J., Yao, L., Hernandez, J., Thompson, I. M., Leach, R. J. & Lehman, D. M., Jan 2014, In: Urologic Oncology: Seminars and Original Investigations. 32, 1, p. 44.e15-44.e20

  Research output: Contribution to journal › Article › peer-review

  • Prostatic Neoplasms
  • Hispanic Americans
  • Chromosomes
  • Odds Ratio
  • Confidence Intervals
• 2013

  Family-based association of an ANK3 haplotype with bipolar disorder in Latino populations

  Gonzalez, S. D., Xu, C., Ramirez, M. E., Zavala, J. M., Armas, R., Contreras, S. A., Contreras, J., Dassori, A., Leach, R. J., Flores, D., Jerez, A., Raventós, H., Ontiveros, A., Nicolini, H. & Escamilla, M., Jun 11 2013, In: Translational psychiatry. 3, e265.

  Research output: Contribution to journal › Letter › peer-review
  5 Scopus citations

• Prostate cancer and prostatic intraepithelial neoplasia: True, true, and unrelated?

  Thompson, I. M. & Leach, R., Feb 10 2013, In: Journal of Clinical Oncology. 31, 5, p. 515-516 2 p.

  Research output: Contribution to journal › Editorial › peer-review
  4 Scopus citations

• Single-cell analysis of circulating tumor cells identifies cumulative expression patterns of EMT-related genes in metastatic prostate cancer

  Chen, C. L., Mahalingam, D., Osmulski, P., Jadhav, R. R., Wang, C. M., Leach, R. J., Chang, T. C., Weitman, S. D., Kumar, A. P., Sun, L., Gaczynska, M. E., Thompson, I. M. & Huang, T. H. M., Jun 2013, In: Prostate. 73, 8, p. 813-826 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Single-Cell Analysis
  • Circulating Neoplastic Cells
  • Epithelial-Mesenchymal Transition
  • Prostatic Neoplasms
  • Genes
  147 Scopus citations

• Suggestive evidence for association between L-type voltage-gated calcium channel (CACNA1C) gene haplotypes and bipolar disorder in Latinos: A family-based association study

  Gonzalez, S., Xu, C., Ramirez, M., Zavala, J., Armas, R., Contreras, S. A., Contreras, J., Dassori, A., Leach, R. J., Flores, D., Jerez, A., Raventós, H., Ontiveros, A., Nicolini, H. & Escamilla, M., Mar 2013, In: Bipolar disorders. 15, 2, p. 206-214 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Calcium Channels
  • Bipolar Disorder
  • Hispanic Americans
  • Haplotypes
  • Single Nucleotide Polymorphism
  18 Scopus citations
• 2012

  Analysis of serum total and free PSA using immunoaffinity depletion coupled to SRM: Correlation with clinical immunoassay tests

  Liu, T., Hossain, M., Schepmoes, A. A., Fillmore, T. L., Sokoll, L. J., Kronewitter, S. R., Izmirlian, G., Shi, T., Qian, W. J., Leach, R. J., Thompson, I. M., Chan, D. W., Smith, R. D., Kagan, J., Srivastava, S., Rodland, K. D. & Camp, D. G., Aug 3 2012, In: Journal of Proteomics. 75, 15, p. 4747-4757 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Prostate-Specific Antigen
  • Immunoassay
  • Assays
  • Mass spectrometry
  • Biomarkers
  39 Scopus citations