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• 2021

  Defining and managing COVID-19-associated pulmonary aspergillosis: the 2020 ECMM/ISHAM consensus criteria for research and clinical guidance

  the Medical Mycology Society of Nigeria, the Medical Mycology Society of China Medicine Education Association, Infectious Diseases Working Party of the German Society for Haematology and Medical Oncology, Association of Medical Microbiology, Infectious Disease Canada, European Confederation of Medical Mycology, the International Society for Human Animal Mycology, the Asia Fungal Working Group, the INFOCUS LATAM/ISHAM Working Group, the ISHAM Pan Africa Mycology Working Group, the European Society for Clinical Microbiology, Infectious Diseases Fungal Infection Study Group, the ESCMID Study Group for Infections in Critically Ill Patients & the Interregional Association of Clinical Microbiology and Antimicrobial Chemotherapy, 2021, (Accepted/In press) In: The Lancet Infectious Diseases.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Pulmonary Aspergillosis
  • Azoles
  • Aspergillus
  • isavuconazole
  • Mycology
  1 Scopus citations
• 2020

  Fosmanogepix (APX001) is effective in the treatment of pulmonary murine mucormycosis due to rhizopus arrhizus

  Gebremariam, T., Alkhazraji, S., Alqarihi, A., Wiederhold, N. P., Shaw, K. J., Patterson, T. F., Filler, S. G. & Ibrahim, A. S., Jun 2020, In: Antimicrobial agents and chemotherapy. 64, 6, e00178-20.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Rhizopus
  • Mucormycosis
  • Inositol
  • Lung
  • isavuconazole
  3 Scopus citations

• Fungal Infections Potentiated by Biologics

  Davis, M. R., Thompson, G. R. & Patterson, T. F., Jun 2020, In: Infectious disease clinics of North America. 34, 2, p. 389-411 23 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Biological Therapy
  • Mycoses
  • Biological Products
  • Opportunistic Infections
  • Protein-Tyrosine Kinases
  1 Scopus citations

• Invasive aspergillosis as an under-recognized superinfection in COVID-19

  Thompson, G. R., Cornely, O. A., Pappas, P. G., Patterson, T. F., Hoenigl, M., Jenks, J. D., Clancy, C. J. & Nguyen, M. H., Jul 1 2020, In: Open Forum Infectious Diseases. 7, 7, ofaa242.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  11 Scopus citations

• Review of influenza-associated pulmonary aspergillosis in ICU patients and proposal for a case definition: an expert opinion

  Verweij, P. E., Rijnders, B. J. A., Brüggemann, R. J. M., Azoulay, E., Bassetti, M., Blot, S., Calandra, T., Clancy, C. J., Cornely, O. A., Chiller, T., Depuydt, P., Giacobbe, D. R., Janssen, N. A. F., Kullberg, B. J., Lagrou, K., Lass-Flörl, C., Lewis, R. E., Liu, P. W. L., Lortholary, O., Maertens, J. & 9 others, Martin-Loeches, I., Nguyen, M. H., Patterson, T. F., Rogers, T. R., Schouten, J. A., Spriet, I., Vanderbeke, L., Wauters, J. & van de Veerdonk, F. L., Aug 1 2020, In: Intensive care medicine. 46, 8, p. 1524-1535 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pulmonary Aspergillosis
  • Expert Testimony
  • Human Influenza
  • Intensive Care Units
  • Aspergillus
  31 Scopus citations

• Revision and update of the consensus definitions of invasive fungal disease from the european organization for research and treatment of cancer and the mycoses study group education and research consortium

  Peter Donnelly, J., Chen, S. C., Kauffman, C. A., Steinbach, W. J., Baddley, J. W., Verweij, P. E., Clancy, C. J., Wingard, J. R., Lockhart, S. R., Groll, A. H., Sorrell, T. C., Bassetti, M., Akan, H., Alexander, B. D., Andes, D., Azoulay, E., Bialek, R., Bradsher, R. W., Bretagne, S., Calandra, T. & 45 others, Caliendo, A. M., Castagnola, E., Cruciani, M., Cuenca-Estrella, M., Decker, C. F., Desai, S. R., Fisher, B., Harrison, T., Heussel, C. P., Jensen, H. E., Kibbler, C. C., Kontoyiannis, D. P., Kullberg, B. J., Lagrou, K., Lamoth, F., Lehrnbecher, T., Loeffler, J., Lortholary, O., Maertens, J., Marchetti, O., Marr, K. A., Masur, H., Meis, J. F., Orla Morrisey, C., Nucci, M., Ostrosky-Zeichner, L., Pagano, L., Patterson, T. F., Perfect, J. R., Racil, Z., Roilides, E., Ruhnke, M., Prokop, C. S., Shoham, S., Slavin, M. A., Stevens, D. A., Thompson, G. R., Vazquez, J. A., Viscoli, C., Walsh, T. J., Warris, A., Joseph Wheat, L., Lewis White, P., Zaoutis, T. E. & Pappas, P. G., Sep 15 2020, In: Clinical Infectious Diseases. 71, 6, p. 1367-1376 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mycoses
  • Organizations
  • Education
  • Manuscripts
  • Neoplasms
  150 Scopus citations

• The novel arylamidine T-2307 demonstrates in vitro and in vivo Activity against Candida auris

  Wiederhold, N. P., Najvar, L. K., Jaramillo, R., Olivo, M., Patterson, H., Connell, A., Fukuda, Y., Mitsuyama, J., Catano, G. & Patterson, T. F., 2020, In: Antimicrobial agents and chemotherapy. 64, 3, e02198.

  Research output: Contribution to journal › Article › peer-review

  • T-2307
  • Candida
  • In Vitro Techniques
  • Kidney
• 2019

  Blastomyces helicus, a New Dimorphic Fungus Causing Fatal Pulmonary and Systemic Disease in Humans and Animals in Western Canada and the United States

  Schwartz, I. S., Wiederhold, N. P., Hanson, K. E., Patterson, T. F. & Sigler, L., Jan 7 2019, In: Clinical Infectious Diseases. 68, 2, p. 188-196 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Blastomyces
  • Canada
  • Fungi
  • Lung Diseases
  • Chrysosporium
  23 Scopus citations

• Current Concepts and Future Directions in the Pharmacology and Treatment of Coccidioidomycosis

  Thompson, G. R., Lewis, J. S., Nix, D. E. & Patterson, T. F., Jan 25 2019, In: Medical mycology. 57, p. S76-S84

  Research output: Contribution to journal › Review article › peer-review

  • Coccidioidomycosis
  • Fluconazole
  • Direction compound
  • Pharmacology
  • Coccidioides
  11 Scopus citations

• Efficacy of delayed therapy with fosmanogepix (APX001) in a murine model of candida auris invasive candidiasis

  Wiederhold, N. P., Najvar, L. K., Shaw, K. J., Jaramillo, R., Patterson, H., Olivo, M., Catano, G. & Patterson, T. F., 2019, In: Antimicrobial agents and chemotherapy. 63, 11, e01120-19.

  Research output: Contribution to journal › Article › peer-review

  • Invasive Candidiasis
  • Candida
  • Fluconazole
  • Caspofungin
  • Glycosylphosphatidylinositols
  13 Scopus citations

• Extended-Interval Dosing of Rezafungin against Azole-Resistant Aspergillus fumigatus

  Wiederhold, N. P., Najvar, L. K., Jaramillo, R., Olivo, M., Wickes, B. L., Catano, G. & Patterson, T. F., 2019, In: Antimicrobial agents and chemotherapy. 63, 10, e01165-19.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Azoles
  • Aspergillus fumigatus
  • posaconazole
  • Echinocandins
  • Aspergillosis
  6 Scopus citations

• New concepts in diagnostics for invasive mycoses: Non-culture-based methodologies

  Patterson, T. F. & Donnelly, J. P., Mar 2019, In: Journal of Fungi. 5, 1, 9.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • mycoses
  • Invasive Fungal Infections
  • infection
  • Aspergillus
  • Candida
  17 Scopus citations

• The Fungal Cyp51-Specific Inhibitor VT-1598 Demonstrates In Vitro and In Vivo Activity against Candida auris

  Wiederhold, N. P., Lockhart, S. R., Najvar, L. K., Berkow, E. L., Jaramillo, R., Olivo, M., Garvey, E. P., Yates, C. M., Schotzinger, R. J., Catano, G. & Patterson, T. F., Mar 2019, In: Antimicrobial agents and chemotherapy. 63, 3, e02233-18.

  Research output: Contribution to journal › Article › peer-review

  • Candida
  • Caspofungin
  • In Vitro Techniques
  • Fluconazole
  • 14-alpha Demethylase Inhibitors
  19 Scopus citations

• Utility of CT assessment in hematology patients with invasive aspergillosis: A post-hoc analysis of phase 3 data

  Jin, J., Wu, D., Liu, Y., Pan, S., Yan, J. L., Aram, J. A., Lou, Y. J., Meng, H., Chen, X., Zhang, XA., Schwartz, I. S. & Patterson, T. F., May 28 2019, In: BMC Infectious Diseases. 19, 1, 471.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Aspergillosis
  • Hematology
  • Tomography
  • Lung
  • Hematopoietic Stem Cell Transplantation
  1 Scopus citations
• 2018

  Agents of Hyalohyphomycosis and Phaeohyphomycosis

  Patterson, T. F. & Sutton, D. A., Jan 1 2018, Principles and Practice of Pediatric Infectious Diseases. Elsevier Inc., p. 1244-1247.e1

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Agents of Mucormycosis

  Patterson, T. F. & Sutton, D. A., 2018, Principles and Practice of Pediatric Infectious Diseases. Elsevier Inc., p. 1247-1250.e1

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Classification of Fungi

  Patterson, T. F. & Sutton, D. A., Jan 1 2018, Principles and Practice of Pediatric Infectious Diseases. Elsevier Inc., p. 1229-1231.e1

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Cryptococcus Species

  Thompson, G. R. & Patterson, T. F., 2018, Principles and Practice of Pediatric Infectious Diseases. Elsevier Inc., p. 1255-1259.e1

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Emergomyces canadensis, a dimorphic fungus causing fatal systemic human disease in North America

  Schwartz, I. S., Sanche, S., Wiederhold, N. P., Patterson, T. F. & Sigler, L., Apr 2018, In: Emerging Infectious Diseases. 24, 4, p. 758-761 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Saskatchewan
  • Hematologic Diseases
  • North America
  • Cervix Uteri
  • Fungi
  18 Scopus citations

• Erratum for Mor et al., "Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids"

  Mor, V., Rella, A., Farnoud, A. M., Singh, A., Munshi, M., Bryan, A., Naseem, S., Konopka, J. B., Ojima, I., Bullesbach, E., Ashbaugh, A., Linke, M. J., Cushion, M., Collins, M., Ananthula, H. K., Sallans, L., Desai, P. B., Wiederhold, N. P., Fothergill, A. W., Kirkpatrick, W. R. & 15 others, Patterson, T., Wong, L. H., Sinha, S., Giaever, G., Nislow, C., Flaherty, P., Pan, X., Cesar, G. V., de Melo Tavares, P., Frases, S., Miranda, K., Rodrigues, M. L., Luberto, C., Nimrichter, L. & Del Poeta, M., Mar 13 2018, In: mBio. 9, 2, e00188-18.

  Research output: Contribution to journal › Comment/debate › peer-review
  4 Scopus citations

• Impact of unresolved neutropenia in patients with neutropenia and invasive aspergillosis: A post hoc analysis of the SECURE trial

  Kontoyiannis, D. P., Selleslag, D., Mullane, K., Cornely, O. A., Hope, W., Lortholary, O., Croos-Dabrera, R., Lademacher, C., Engelhardt, M. & Patterson, T. F., Mar 1 2018, In: Journal of Antimicrobial Chemotherapy. 73, 3, p. 757-763 7 p.

  Research output: Contribution to journal › Article › peer-review

  • isavuconazole
  • Voriconazole
  • Aspergillosis
  • Neutropenia
  • Mortality
  14 Scopus citations

• In vivo efficacy of VT-1129 against experimental cryptococcal meningitis with the use of a loading dose-maintenance dose administration strategy

  Wiederhold, N. P., Xu, X., Wang, A., Najvar, L. K., Garvey, E. P., Ottinger, E. A., Alimardanov, A., Cradock, J., Behnke, M., Hoekstra, W. J., Brand, S. R., Schotzinger, R. J., Jaramillo, R., Olivo, M., Kirkpatrick, W. R. & Pattersona, T. F., Nov 2018, In: Antimicrobial agents and chemotherapy. 62, 11, e01315-18.

  Research output: Contribution to journal › Article › peer-review

  • VT-1129
  • Cryptococcal Meningitis
  • Brain
  • Placebos
  • Cryptococcus neoformans
  6 Scopus citations

• Malassezia Species

  Sutton, D. A. & Patterson, T. F., 2018, Principles and Practice of Pediatric Infectious Diseases. Elsevier Inc., p. 1250-1253.e1

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Novel approaches to antifungal therapy

  Thompson, G. R. & Patterson, T. F., Feb 1 2018, In: American Journal of Transplantation. 18, 2, p. 287-288 2 p.

  Research output: Contribution to journal › Editorial › peer-review
  1 Scopus citations

• Oral glucan synthase inhibitor SCY-078 is effective in an experimental murine model of invasive candidiasis caused by WT and echinocandin-resistant Candida glabrata

  Wiederhold, N. P., Najvar, L. K., Jaramillo, R., Olivo, M., Pizzini, J., Catano, G. & Patterson, T. F., Feb 1 2018, In: The Journal of antimicrobial chemotherapy. 73, 2, p. 448-451 4 p.

  Research output: Contribution to journal › Article › peer-review

  • MK-3118
  • glucan synthase
  • Invasive Candidiasis
  • Echinocandins
  • Candida glabrata
  14 Scopus citations

• Screening a repurposing library for inhibitors of multidrug-resistant candida auris identifies ebselen as a repositionable candidate for antifungal drug development

  Wall, G., Chaturvedi, A. K., Wormley, F. L., Wiederhold, N. P., Patterson, H. P., Patterson, T. F. & Lopez-Ribot, J. L., Oct 2018, In: Antimicrobial agents and chemotherapy. 62, 10, e01084.

  Research output: Contribution to journal › Article › peer-review

  • ebselen
  • Candida
  • Drug Development
  • Libraries
  • Fungi
  28 Scopus citations

• Sporothrix schenckii Complex (Sporotrichosis)

  Patterson, T. F. & Sutton, D. A., Jan 1 2018, Principles and Practice of Pediatric Infectious Diseases. Elsevier Inc., p. 1253-1255.e1

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• The Emerging Threat of Antifungal Resistance in Transplant Infectious Diseases

  Schwartz, I. S. & Patterson, T. F., Mar 1 2018, In: Current Infectious Disease Reports. 20, 3, 2.

  Research output: Contribution to journal › Review article › peer-review

  • Candida
  • Communicable Diseases
  • Transplants
  • Transplantation
  • Invasive Candidiasis
  19 Scopus citations

• The fungal cyp51 inhibitor vt-1129 is efficacious in an experimental model of cryptococcal meningitis

  Wiederhold, N. P., Najvar, L. K., Garvey, E. P., Brand, S. R., Xu, X., Ottinger, E. A., Alimardanov, A., Cradock, J., Behnke, M., Hoekstra, W. J., Schotzinger, R. J., Jaramillo, R., Olivo, M., Kirkpatrick, W. R. & Patterson, T. F., Sep 2018, In: Antimicrobial agents and chemotherapy. 62, 9, e01071-18.

  Research output: Contribution to journal › Article › peer-review

  • VT-1129
  • Cryptococcal Meningitis
  • Theoretical Models
  • Fluconazole
  • Brain
  8 Scopus citations

• The novel fungal Cyp51 inhibitor VT-1598 is efficacious in experimental models of central nervous system coccidioidomycosis caused by Coccidioides posadasii and Coccidioides immitis

  Wiederhold, N. P., Shubitz, L. F., Najvar, L. K., Jaramillo, R., Olivo, M., Catano, G., Trinh, H. T., Yates, C. M., Schotzinger, R. J., Garvey, E. P. & Patterson, T. F., Apr 2018, In: Antimicrobial agents and chemotherapy. 62, 4, e02258-17.

  Research output: Contribution to journal › Article › peer-review

  • Coccidioides
  • Coccidioidomycosis
  • Theoretical Models
  • Central Nervous System
  • Survival
  21 Scopus citations

• The orotomide olorofim is efficacious in an experimental model of central nervous system coccidioidomycosis

  Wiederhold, N. P., Najvar, L. K., Jaramillo, R., Olivo, M., Birch, M., Law, D., Rex, J. H., Catano, G. & Patterson, T. F., Sep 2018, In: Antimicrobial agents and chemotherapy. 62, 9, e00999-18.

  Research output: Contribution to journal › Article › peer-review

  • olorofim
  • Coccidioidomycosis
  • Theoretical Models
  • Central Nervous System
  • Coccidioides
  11 Scopus citations
• 2017

  Modified release itraconazole amorphous solid dispersion to treat Aspergillus fumigatus: importance of the animal model selection

  Maincent, J. P., Najvar, L. K., Kirkpatrick, W. R., Huang, S., Patterson, T. F., Wiederhold, N. P., Peters, J. I. & Williams, R. O., Feb 1 2017, In: Drug Development and Industrial Pharmacy. 43, 2, p. 264-274 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Aspergillus
  • Aspergillus fumigatus
  • Itraconazole
  • Animals
  • Animal Models
  5 Scopus citations

• Multidrug-resistant candida: Epidemiology, molecular mechanisms, and treatment

  Arendrup, M. C. & Patterson, T. F., Jan 15 2017, In: Journal of Infectious Diseases. 216, p. S445-S451

  Research output: Contribution to journal › Article › peer-review

  • Molecular Epidemiology
  • Candida
  • Multiple Drug Resistance
  • Candida glabrata
  • Infection
  151 Scopus citations

• Multiple Brain Abscesses Caused by Trichosporon inkin in a Patient with X-Linked Chronic Granulomatous Disease (CGD) Successfully Treated with Antifungal Therapy

  Hajjar, J., Restrepo, A., Javeri, H., Wiederhold, N. P., Papanastassiou, A. M. & Patterson, T. F., Aug 1 2017, In: Journal of Clinical Immunology. 37, 6, p. 519-523 5 p.

  Research output: Contribution to journal › Letter › peer-review
  1 Scopus citations

• Prophylactic treatment with VT-1161 protects immunosuppressed mice from rhizopus arrhizus var. Arrhizus infection

  Gebremariam, T., Alkhazraji, S., Lin, L., Wiederhold, N. P., Garvey, E. P., Hoekstra, W. J., Schotzinger, R. J., Patterson, T. F., Filler, S. G. & Ibrahim, A. S., Sep 2017, In: Antimicrobial agents and chemotherapy. 61, 9, e00390-17.

  Research output: Contribution to journal › Article › peer-review

  • VT-1161
  • Rhizopus
  • posaconazole
  • Mucormycosis
  • Infection
  12 Scopus citations

• Repurposing auranofin as an antifungal: In vitro activity against a variety of medically important fungi

  Wiederhold, N. P., Patterson, T. F., Srinivasan, A., Chaturvedi, A. K., Fothergill, A. W., Wormley, F. L., Ramasubramanian, A. K. & Lopez-Ribot, J. L., Feb 17 2017, In: Virulence. 8, 2, p. 138-142 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Gold Compounds
  • Auranofin
  • Action Spectrum
  • Drug Repositioning
  • Sulfhydryl Compounds
  33 Scopus citations

• The carbohydrate lectin receptor dectin-1 mediates the immune response to Exserohilum rostratum

  Reedy, J. L., Negoro, P. E., Feliu, M., Lord, A. K., Khan, N. S., Lukason, D. P., Wiederholdc, N. P., Tam, J. M., Mansour, M. K., Patterson, T. F. & Vyas, J. M., 2017, In: Infection and immunity. 85, 3, e00903.

  Research output: Contribution to journal › Article › peer-review

  • dectin 1
  • Mitogen Receptors
  • Carbohydrates
  • Macrophages
  • Spores
  7 Scopus citations
• 2016

  Effect of antifungal treatment in a diet-based murine model of disseminated candidiasis acquired via the gastrointestinal tract

  Kadosh, D., Najvar, L. K., Bocanegra, R., Olivo, M., Kirkpatrick, W. R., Wiederhold, N. P. & Patterson, T. F., Nov 2016, In: Antimicrobial agents and chemotherapy. 60, 11, p. 6703-6708 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Candidiasis
  • Gastrointestinal Tract
  • Diet
  • Candida albicans
  • Immunosuppression
  6 Scopus citations

• Executive summary: Practice guidelines for the diagnosis and management of aspergillosis: 2016 update by the infectious diseases society of America

  Patterson, T. F., Thompson, G. R., Denning, D. W., Fishman, J. A., Hadley, S., Herbrecht, R., Kontoyiannis, D. P., Marr, K. A., Morrison, V. A., Nguyen, M. H., Segal, B. H., Steinbach, W. J., Stevens, D. A., Walsh, T. J., Wingard, J. R., Young, J. A. H. & Bennett, J. E., Aug 15 2016, In: Clinical Infectious Diseases. 63, 4, p. 433-442 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • Practice Management
  • Aspergillosis
  • Practice Guidelines
  • Communicable Diseases
  • Guideline Adherence
  196 Scopus citations

• Invasive Aspergillosis: Current Strategies for Diagnosis and Management

  Cadena, J., Thompson, G. R. & Patterson, T. F., Mar 1 2016, In: Infectious Disease Clinics of North America. 30, 1, p. 125-142 18 p.

  Research output: Contribution to journal › Article › peer-review

  • Aspergillosis
  • Decision Making
  • Voriconazole
  • Routine Diagnostic Tests
  • Sensitivity and Specificity
  42 Scopus citations

• Isavuconazole is effective for the treatment of experimental cryptococcal meningitis

  Wiederhold, N. P., Kovanda, L., Najvar, L. K., Bocanegra, R., Olivo, M., Kirkpatrick, W. R. & Patterson, T. F., Sep 1 2016, In: Antimicrobial agents and chemotherapy. 60, 9, p. 5600-5603 4 p.

  Research output: Contribution to journal › Article › peer-review

  • isavuconazole
  • Cryptococcal Meningitis
  • Cryptococcus neoformans
  • Fluconazole
  • Brain
  26 Scopus citations

• Isavuconazole versus voriconazole for primary treatment of invasive mould disease caused by Aspergillus and other filamentous fungi (SECURE): A phase 3, randomised-controlled, non-inferiority trial

  Maertens, J. A., Raad, I. I., Marr, K. A., Patterson, T. F., Kontoyiannis, D. P., Cornely, O. A., Bow, E. J., Rahav, G., Neofytos, D., Aoun, M., Baddley, J. W., Giladi, M., Heinz, W. J., Herbrecht, R., Hope, W., Karthaus, M., Lee, D. G., Lortholary, O., Morrison, V. A., Oren, I. & 8 others, Selleslag, D., Shoham, S., Thompson, G. R., Lee, M., Maher, R. M., Schmitt-Hoffmann, A. H., Zeiher, B. & Ullmann, A. J., Feb 20 2016, In: The Lancet. 387, 10020, p. 760-769 10 p.

  Research output: Contribution to journal › Article › peer-review

  • isavuconazole
  • Equivalence Trials
  • Voriconazole
  • Aspergillus
  • Fungi
  379 Scopus citations

• Practice guidelines for the diagnosis and management of aspergillosis: 2016 update by the infectious diseases society of America

  Patterson, T. F., Thompson, G. R., Denning, D. W., Fishman, J. A., Hadley, S., Herbrecht, R., Kontoyiannis, D. P., Marr, K. A., Morrison, V. A., Nguyen, M. H., Segal, B. H., Steinbach, W. J., Stevens, D. A., Walsh, T. J., Wingard, J. R., Young, J. A. H. & Bennett, J. E., Aug 15 2016, In: Clinical Infectious Diseases. 63, 4, p. e1-e60

  Research output: Contribution to journal › Review article › peer-review

  • Practice Management
  • Aspergillosis
  • Practice Guidelines
  • Communicable Diseases
  • Guideline Adherence
  848 Scopus citations

• The celecoxib derivative AR-12 has broad-spectrum antifungal activity in vitro and improves the activity of fluconazole in a murine model of cryptococcosis

  Koselny, K., Green, J., DiDone, L., Halterman, J. P., Fothergill, A. W., Wiederhold, N. P., Patterson, T. F., Cushion, M. T., Rappelye, C., Wellington, M. & Krysan, D. J., Dec 2016, In: Antimicrobial agents and chemotherapy. 60, 12, p. 7115-7127 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Cryptococcosis
  • Celecoxib
  • Fluconazole
  • Candida
  • Echinocandins
  39 Scopus citations

• The epidemiology and outcomes of invasive Candida infections among organ transplant recipients in the United States: results of the Transplant-Associated Infection Surveillance Network (TRANSNET)

  The TRANSNET Investigators, Dec 1 2016, In: Transplant Infectious Disease. 18, 6, p. 921-931 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Invasive Candidiasis
  • Candida
  • Transplant Recipients
  • Epidemiology
  • Transplants
  72 Scopus citations

• The investigational fungal Cyp51 inhibitor VT-1129 demonstrates potent in vitro activity against cryptococcus neoformans and cryptococcus gattii

  Lockhart, S. R., Fothergill, A. W., Iqbal, N., Bolden, C. B., Grossman, N. T., Garvey, E. P., Brand, S. R., Hoekstra, W. J., Schotzinger, R. J., Ottinger, E., Patterson, T. F. & Wiederhold, N. P., Apr 2016, In: Antimicrobial agents and chemotherapy. 60, 4, p. 2528-2531 4 p.

  Research output: Contribution to journal › Article › peer-review

  • VT-1129
  • Cryptococcus gattii
  • Cryptococcus neoformans
  • Fluconazole
  • Cryptococcus
  39 Scopus citations

• The novel arylamidine T-2307 demonstrates in vitro and in vivo activity against echinocandin-resistant Candida glabrata

  Wiederhold, N. P., Najvar, L. K., Fothergill, A. W., Bocanegra, R., Olivo, M., McCarthy, D. I., Fukuda, Y., Mitsuyama, J. & Patterson, T. F., Mar 1 2016, In: Journal of Antimicrobial Chemotherapy. 71, 3, p. 692-695 4 p.

  Research output: Contribution to journal › Article › peer-review

  • T-2307
  • Echinocandins
  • Candida glabrata
  • Caspofungin
  • In Vitro Techniques
  12 Scopus citations
• 2015

  Antifungal agents

  Thompson, G. R. & Patterson, T. F., Jan 1 2015, Infections in Hematology. Springer Berlin Heidelberg, p. 259-272 14 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • deoxycholate drug combination amphotericin B
  • Anidulafungin
  • Micafungin
  • posaconazole
  • Caspofungin
  1 Scopus citations

• Antifungal therapy

  Wiederhold, N. & Patterson, T. F., Jan 1 2015, Clinical Infectious Disease, Second Edition. Cambridge University Press, p. 1344-1352 9 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Amphotericin B
  • Deoxycholic Acid
  • Sterols
  • Mycoses
  • Polyenes

• Application of the 2008 definitions for invasive fungal diseases to the trial comparing voriconazole versus amphotericin B for therapy of invasive aspergillosis: A Collaborative Study of the Mycoses Study Group (MSG 05) and the European Organization for Research and Treatment of Cancer Infectious Diseases Group

  Herbrecht, R., Patterson, T. F., Slavin, M. A., Marchetti, O., Maertens, J., Johnson, E. M., Schlamm, H. T., Donnelly, J. P. & Pappas, P. G., Mar 1 2015, In: Clinical Infectious Diseases. 60, 5, p. 713-720 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Sodium Glutamate
  • Voriconazole
  • Aspergillosis
  • Amphotericin B
  • Mycoses
  55 Scopus citations