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• 2019

  Disulfide bond of Mycoplasma pneumoniae community-acquired respiratory distress syndrome toxin is essential to maintain the ADP-ribosylating and vacuolating activities

  Balasubramanian, S., Pandranki, L., Maupin, S., Ramasamy, K., Taylor, A. B., Hart, P. J., Baseman, J. B. & Kannan, T. R., Aug 2019, In: Cellular Microbiology. 21, 8, e13032.

  Research output: Contribution to journal › Editorial › peer-review

  • Mycoplasma pneumoniae
  • Disulfides
  • Adenosine Diphosphate
  • ADP Ribose Transferases
  • NAD-cysteine ADP-ribosyltransferase
  2 Scopus citations
• 2018

  Mycoplasma pneumoniae community-acquired respiratory distress syndrome toxin uses a novel KELED sequence for retrograde transport and subsequent cytotoxicity

  Ramasamy, K., Balasubramanian, S., Manickam, K., Pandranki, L., Taylor, A. B., Hart, P. J., Baseman, J. B. & Kannan, T. R., Jan 1 2018, In: mBio. 9, 1, e01663-17.

  Research output: Contribution to journal › Article › peer-review

  • Mycoplasma pneumoniae
  • Endoplasmic Reticulum
  • Adenosine Diphosphate
  • Pneumonia
  • Amino Acids
  4 Scopus citations

• NLRP3 is a critical regulator of inflammation and innate immune cell response during Mycoplasma pneumoniae infection

  Segovia, J. A., Chang, T. H., Winter, V. T., Coalson, J. J., Cagle, M. P., Pandranki, L., Bose, S., Baseman, J. B. & Kannan, T. R., Jan 1 2018, In: Infection and immunity. 86, 1, e00548-17.

  Research output: Contribution to journal › Article › peer-review

  • leucine-rich repeat proteins
  • Mycoplasma Pneumonia
  • Mycoplasma pneumoniae
  • Inflammasomes
  • Innate Immunity
  31 Scopus citations

• The immunopathologic effects of mycoplasma pneumoniae and community-acquired respiratory distress syndrome toxin a primate model

  Maselli, D. J., Medina, J. L., Brooks, E. G., Coalson, J. J., Kannan, T. R., Winter, V. T., Principe, M., Cagle, M. P., Baseman, J. B., Dube, P. H. & Peters, J. I., Feb 2018, In: American journal of respiratory cell and molecular biology. 58, 2, p. 253-260 8 p.

  Research output: Contribution to journal › Editorial › peer-review

  • Mycoplasma pneumoniae
  • Animals
  • Primates
  • T-cells
  • Dimercaprol
  14 Scopus citations
• 2017

  Mycoplasma pneumoniae and health outcomes in children with asthma

  Wood, P. R., Kampschmidt, J. C., Dube, P. H., Cagle, M. P., Chaparro, P., Ketchum, N. S., Kannan, T. R., Singh, H., Peters, J. I., Baseman, J. B. & Brooks, E. G., Aug 2017, In: Annals of Allergy, Asthma and Immunology. 119, 2, p. 146-152.e2

  Research output: Contribution to journal › Article › peer-review

  • Mycoplasma pneumoniae
  • Asthma
  • Health
  • Child
  • Respiratory System
  9 Scopus citations

• The cryptic plasmid is more important for Chlamydia muridarum to colonize the mouse gastrointestinal tract than to infect the genital tract

  Shao, L., Melero, J., Zhang, N., Arulanandam, B., Baseman, J., Liu, Q. & Zhong, G., May 2017, In: PloS one. 12, 5, e0177691.

  Research output: Contribution to journal › Article › peer-review

  • Chlamydia muridarum
  • genitalia
  • gastrointestinal system
  • Genitalia
  • Gastrointestinal Tract
  18 Scopus citations
• 2016

  Intravenous inoculation with chlamydia muridarum leads to a long-lasting infection restricted to the gastrointestinal tract

  Dai, J., Zhang, T., Wang, L., Shao, L., Zhu, C., Zhang, Y., Failor, C., Schenken, R., Baseman, J., He, C. & Zhong, G., 2016, In: Infection and immunity. 84, 8, p. 2382-2388 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Chlamydia muridarum
  • Gastrointestinal Tract
  • Infection
  • Luciferases
  • Veins
  23 Scopus citations
• 2015

  Intrauterine infection with plasmid-free Chlamydia muridarum reveals a critical role of the plasmid in chlamydial ascension and establishes a model for evaluating plasmid-independent pathogenicity

  Chen, J., Yang, Z., Sun, X., Tang, L., Ding, Y., Xue, M., Zhou, Z., Baseman, J. & Zhong, G., 2015, In: Infection and immunity. 83, 6, p. 2583-2592 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Chlamydia muridarum
  • Virulence
  • Plasmids
  • Inbred CBA Mouse
  • Infection
  16 Scopus citations

• Regulation of TLR3 activation by S100A9

  Tsai, S. Y., Segovia, J. A., Chang, T. H., Shil, N. K., Pokharel, S. M., Kannan, T. R., Baseman, J. B., Defrêne, J., Pagé, N., Cesaro, A., Tessier, P. A. & Bose, S., Nov 2015, In: Journal of Immunology. 195, 9, p. 4426-4437 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Endosomes
  • Macrophages
  • Lysosomes
  • Calgranulin B
  • RNA Virus Infections
  16 Scopus citations

• Structure of CARDS toxin, a unique ADP-ribosylating and vacuolating cytotoxin from Mycoplasma pneumoniae

  Becker, A., Kannan, T. R., Taylor, A. B., Pakhomova, O. N., Zhang, Y., Somarajan, S. R., Galaleldeen, A., Holloway, S. P., Baseman, J. B. & Hart, P. J., Apr 21 2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 16, p. 5165-5170 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Mycoplasma pneumoniae
  • Cytotoxins
  • Adenosine Diphosphate
  • ADP Ribose Transferases
  • Lotus
  31 Scopus citations
• 2014

  ADP-Ribosylation of NLRP3 by Mycoplasma pneumoniae CARDS toxin regulates inflammasome activity

  Bose, S., Segovia, J. A., Somarajan, S. R., Chang, T. H., Kannan, T. R. & Baseman, J. B., Dec 23 2014, In: mBio. 5, 6, e02186-14.

  Research output: Contribution to journal › Article › peer-review

  • ADP-Ribosylation
  • Mycoplasma pneumoniae
  • Inflammasomes
  • ADP Ribose Transferases
  • Inflammation
  42 Scopus citations

• Annexin A2 mediates mycoplasma pneumoniae community-acquired respiratory distress syndrome toxin binding to eukaryotic cells

  Somarajan, S. R., Al-Asadi, F., Ramasamy, K., Pandranki, L., Baseman, J. B. & Kannan, T. R., Aug 19 2014, In: mBio. 5, 4, e01497-14.

  Research output: Contribution to journal › Article › peer-review

  • Annexins
  • Mycoplasma pneumoniae
  • Annexin A2
  • Eukaryotic Cells
  • A549 Cells
  18 Scopus citations

• Chlamydial induction of hydrosalpinx in 11 strains of mice reveals multiple host mechanisms for preventing upper genital tract pathology

  Chen, J., Zhang, H., Zhou, Z., Yang, Z., Ding, Y., Zhou, Z., Zhong, E., Arulanandam, B., Baseman, J. & Zhong, G., Apr 15 2014, In: PloS one. 9, 4, e95076.

  Research output: Contribution to journal › Article › peer-review

  • Pathology
  • genitalia
  • Genitalia
  • Ascension
  • mice
  45 Scopus citations

• Chlamydial induction of hydrosalpinx in 11 strains of mice reveals multiple host mechanisms for preventing upper genital tract pathology

  Chen, J., Zhang, H., Zhou, Z., Yang, Z., Ding, Y., Zhou, Z., Zhong, E., Arulanandam, B., Baseman, J. & Zhong, G., Apr 1 2014, In: PLoS One. 9, 4, e0095076.

  Research output: Contribution to journal › Article › peer-review

  • Pathology
  • genitalia
  • Genitalia
  • Ascension
  • mice

• Functional characterization of osmotically inducible protein C (MG_427) from Mycoplasma genitalium

  Zhang, W. & Baseman, J. B., Mar 1 2014, In: Journal of Bacteriology. 196, 5, p. 1012-1019 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Mycoplasma genitalium
  • Protein C
  • Oxidative Stress
  • Bacteria
  • Genome Size
  18 Scopus citations

• Functional mapping of community-acquired respiratory distress syndrome (CARDS) toxin of Mycoplasma pneumoniae defines regions with ADP-ribosyltransferase, vacuolating and receptor-binding activities

  Kannan, T. R., Krishnan, M., Ramasamy, K., Becker, A., Pakhomova, O. N., Hart, P. J. & Baseman, J. B., Aug 2014, In: Molecular Microbiology. 93, 3, p. 568-581 14 p.

  Research output: Contribution to journal › Article › peer-review

  • ADP Ribose Transferases
  • Purinergic P2 Receptors
  • Mycoplasma pneumoniae
  • Mycoplasma Pneumonia
  • Site-Directed Mutagenesis
  14 Scopus citations

• Induction of protective immunity against Chlamydia muridarum intracervical infection in DBA/1j mice

  Tang, L., Yang, Z., Zhang, H., Zhou, Z., Arulanandam, B., Baseman, J. & Zhong, G., Mar 10 2014, In: Vaccine. 32, 12, p. 1407-1413 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Chlamydia muridarum
  • Inbred DBA Mouse
  • vaccination
  • immunity
  • Immunity
  16 Scopus citations

• Lack of long-lasting hydrosalpinx in A/J mice correlates with rapid but transient chlamydial ascension and neutrophil recruitment in the oviduct following intravaginal inoculation with Chlamydia muridarum

  Zhang, H., Zhou, Z., Chen, J., Wu, G., Yang, Z., Zhou, Z., Baseman, J., Zhang, J., Reddick, R. L. & Zhong, G., Jul 2014, In: Infection and immunity. 82, 7, p. 2688-2696 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Chlamydia muridarum
  • Oviducts
  • Neutrophil Infiltration
  • Inbred CBA Mouse
  • Infection
  32 Scopus citations

• Mycoplasma pneumoniae CARDS toxin exacerbates ovalbumin-induced asthma-like inflammation in BALB/c mice

  Medina, J. L., Coalson, J. J., Brooks, E. G., Le Saux, C. J., Winter, V. T., Chaparro, A., Principe, M. F. R., Solis, L., Kannan, T. R., Baseman, J. B. & Dube, P. H., Jul 24 2014, In: PloS one. 9, 7, e102613.

  Research output: Contribution to journal › Article › peer-review

  • Mycoplasma pneumoniae
  • distress
  • ovalbumin
  • asthma
  • Ovalbumin
  18 Scopus citations

• Plasmid-encoded Pgp3 is a major virulence factor for Chlamydia muridarum to induce hydrosalpinx in mice

  Liu, Y., Huang, Y., Yang, Z., Sun, Y., Gong, S., Hou, S., Chen, C., Li, Z., Liu, Q., Wu, Y., Baseman, J. & Zhong, G., Jan 1 2014, In: Infection and Immunity. 82, 12, p. 5327-5335 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Chlamydia muridarum
  • Virulence Factors
  • Plasmids
  • Genitalia
  • Virulence
  64 Scopus citations

• Reduced live organism recovery and lack of hydrosalpinx in mice infected with plasmid-free Chlamydia muridarum

  Lei, L., Chen, J., Hou, S., Ding, Y., Yang, Z., Zeng, H., Baseman, J. & Zhong, G., Mar 1 2014, In: Infection and Immunity. 82, 3, p. 983-992 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Chlamydia muridarum
  • Plasmids
  • Oviducts
  • Genitalia
  • Virulence
  52 Scopus citations

• Transformation of Chlamydia muridarum reveals a role for Pgp5 in suppression of plasmid-dependent gene expression

  Liu, Y., Chen, C., Gong, S., Hou, S., Qi, M., Liu, Q., Baseman, J. & Zhong, G., Mar 2014, In: Journal of bacteriology. 196, 5, p. 989-998 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Chlamydia muridarum
  • Chlamydia trachomatis
  • Plasmids
  • Gene Expression
  • Genes
  49 Scopus citations
• 2013

  Mycoplasma: Curiosity and pathogen

  Baseman, J. B. & Waites, K. B., Jul 8 2013, Schaechter's Mechanisms of Microbial Disease: Fifth Edition. Wolters Kluwer Health Adis (ESP), p. 308-313 6 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Mycoplasma pneumoniae CARDS Toxin Is Internalized via Clathrin-Mediated Endocytosis

  Krishnan, M., Kannan, T. R. & Baseman, J. B., May 7 2013, In: PloS one. 8, 5, e62706.

  Research output: Contribution to journal › Article › peer-review

  • Mycoplasma pneumoniae
  • clathrin
  • Clathrin
  • distress
  • endocytosis
  22 Scopus citations

• Mycoplasma pneumoniae in children with acute and refractory asthma

  Wood, P. R., Hill, V. L., Burks, M. L., Peters, J. I., Singh, H., Kannan, T. R., Vale, S., Cagle, M. P., Principe, M. F. R., Baseman, J. B. & Brooks, E. G., May 2013, In: Annals of Allergy, Asthma and Immunology. 110, 5, p. 328-334.e1

  Research output: Contribution to journal › Article › peer-review

  • Mycoplasma pneumoniae
  • Asthma
  • Pneumonia
  • Child
  • Quality of Life
  58 Scopus citations

• Oviduct Infection and Hydrosalpinx in DBA1/j Mice Is Induced by Intracervical but Not Intravaginal Inoculation with Chlamydia muridarum

  Tang, L., Zhang, H., Lei, L., Gong, S., Zhou, Z., Baseman, J. & Zhong, G., Aug 5 2013, In: PloS one. 8, 8, e71649.

  Research output: Contribution to journal › Article › peer-review

  • Chlamydia muridarum
  • Oviducts
  • oviducts
  • Tissue
  • mice
  37 Scopus citations
• 2012

  Fatal outcomes in family transmission of mycoplasma pneumoniae

  Kannan, T. R., Hardy, R. D., Coalson, J. J., Cavuoti, D. C., Siegel, J. D., Cagle, M., Musatovova, O., Herrera, C. & Baseman, J. B., Jan 15 2012, In: Clinical Infectious Diseases. 54, 2, p. 225-231 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Mycoplasma pneumoniae
  • Fatal Outcome
  • Siblings
  • Cryptogenic Organizing Pneumonia
  • Autopsy
  30 Scopus citations

• Mycoplasma: Curiosity and pathogen

  Baseman, J. B. & Waites, K. B., May 15 2012, Schaechter's Mechanisms of Microbial Disease: Fifth Edition. Wolters Kluwer Health Adis (ESP), p. 308-313 6 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Mycoplasma pneumoniae CARDS toxin induces pulmonary eosinophilic and lymphocytic inflammation

  Medina, J. L., Coalson, J. J., Brooks, E. G., Winter, V. T., Chaparro, A., Principe, M. F. R., Kannan, T. R., Baseman, J. B. & Dube, P. H., Jun 2012, In: American journal of respiratory cell and molecular biology. 46, 6, p. 815-822 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Mycoplasma pneumoniae
  • T-cells
  • Inflammation
  • Chemokine CCL22
  • Lung
  49 Scopus citations

• Mycoplasma pneumoniae Large DNA Repetitive Elements RepMP1 Show Type Specific Organization among Strains

  Musatovova, O., Kannan, T. R. & Baseman, J. B., Oct 16 2012, In: PloS one. 7, 10, e47625.

  Research output: Contribution to journal › Article › peer-review

  • Mycoplasma pneumoniae
  • Genes
  • DNA
  • Genome
  • Tandem Repeat Sequences
  8 Scopus citations