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2021
Adoptive Transfer of Group 3-Like Innate Lymphoid Cells Restores Mouse Colon Resistance to Colonization of a Gamma Interferon-Susceptible Chlamydia muridarum Mutant
He, Y., Xu, H., Song, C., Koprivsek, J. J., Arulanandam, B., Yang, H., Tao, L. & Zhong, G., Feb 2021, In: Infection and immunity. 89, 2, e00533.Research output: Contribution to journal › Article › peer-review
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2020
Chlamydia deficient in plasmid-encoded pgp3 is prevented from spreading to large intestine
Huo, Z., He, C., Xu, Y., Jia, T., Wang, J. & Zhong, G., Jun 1 2020, In: Infection and immunity. 88, 6, e00120.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Effectiveness of Platelet-Rich Plasma in the Prevention of Chlamydia-Induced Hydrosalpinx in a Murine Model
Rippentrop, S. M., Huo, Z., Zhou, Z., Zaldana, F., Hernandez, S., Robinson, R. D. & Zhong, G., 2020, (Accepted/In press) In: Reproductive Sciences.Research output: Contribution to journal › Article › peer-review
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Evasion of innate lymphoid cell-regulated gamma interferon responses by chlamydia muridarum to achieve long-lasting colonization in mouse colon
Koprivsek, J. J., He, Y., Song, C., Zhang, N., Tumanov, A. & Zhong, G., Mar 1 2020, In: Infection and immunity. 88, 3, e00798-19.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Gastrointestinal coinfection promotes chlamydial pathogenicity in the genital tract
Tian, Q., Zhou, Z., Wang, L., Abu-Khdeir, A. M. H., Huo, Z., Sun, X., Zhang, N., Schenken, R., Wang, Y., Xue, M. & Zhong, G., Mar 1 2020, In: Infection and immunity. 88, 4, e00905-19.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Innate lymphoid cells are required for endometrial resistance to chlamydia trachomatis infection
Xu, H., Su, X., Zhao, Y., Tang, L., Chen, J. & Zhong, G., Jul 1 2020, In: Infection and immunity. 88, 7, e00152-20.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Proteome array of antibody responses to Chlamydia trachomatis infection in nonhuman primates
Lu, C., Sun, Z., Chen, H., Chen, L., Zhu, C., Chen, C., Li, C., Peng, B. & Zhong, G., May 1 2020, In: Life Sciences. 248, 117444.Research output: Contribution to journal › Article › peer-review
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Suppression of chlamydial pathogenicity by nonspecific CD8+t lymphocytes
Xie, L., He, C., Chen, J., Tang, L., Zhou, Z. & Zhong, G., Oct 2020, In: Infection and immunity. 88, 10, e00315.Research output: Contribution to journal › Article › peer-review
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The cryptic plasmid improves chlamydia fitness in different regions of the gastrointestinal tract
Ma, J., He, C., Huo, Z., Xu, Y., Arulanandam, B., Liu, Q. & Zhong, G., Mar 1 2020, In: Infection and immunity. 88, 3, e00860-19.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
2019
Antigen-specific CD4 T cell-derived gamma interferon is both necessary and sufficient for clearing chlamydia from the small intestine but not the large intestine
Lin, H., He, C., Koprivsek, J. J., Chen, J., Zhou, Z., Arulanandam, B., Xu, Z., Tang, L. & Zhong, G., 2019, In: Infection and immunity. 87, 6, e00055-19.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
A primary study on genes with selected mutations by in vitro passage of Chlamydia muridarum strains
Zhou, Z., Liu, N., Wang, Y., Emmanuel, A. W., You, X., Liu, J., Li, Z., Wu, Y. & Zhong, G., Apr 1 2019, In: Pathogens and disease. 77, 3, ftz017.Research output: Contribution to journal › Article › peer-review
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Chlamydial plasmid-encoded virulence factor Pgp3 interacts with human cathelicidin peptide LL-37 to modulate immune response
Hou, S., Sun, X., Dong, X., Lin, H., Tang, L., Xue, M. & Zhong, G., Jan 1 2019, In: Microbes and Infection. 21, 1, p. 50-55 6 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Chlamydia muridarum induces pathology in the female upper genital tract via distinct mechanisms
Yu, H., Lin, H., Xie, L., Tang, L., Chen, J., Zhou, Z., Ni, J. & Zhong, G., 2019, In: Infection and immunity. 87, 8, e00145.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Distinct roles of chromosome- versus plasmid-encoded genital tract virulence factors in promoting chlamydia muridarum colonization in the gastrointestinal tract
Koprivsek, J. J., Zhang, T., Tian, Q., He, Y., Xu, H., Xu, Z. & Zhong, G., 2019, In: Infection and immunity. 87, 8, e00265.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
IL-10通过抑制IFN-γ和IL-2表达促进鼠衣原体感染
He, Q., He, M., Wang, X., Luo, X., Wu, Y. & Zhong, G., Feb 28 2019, In: Chinese Journal of Microbiology and Immunology (China). 39, 2, p. 126-130 5 p.Research output: Contribution to journal › Article › peer-review
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National Institute of Allergy and Infectious Diseases workshop report: “Chlamydia vaccines: The way forward”
Zhong, G., Brunham, R. C., de la Maza, L. M., Darville, T. & Deal, C., Nov 28 2019, In: Vaccine. 37, 50, p. 7346-7354 9 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
The plasmid-encoded PGP3 promotes chlamydia evasion of acidic barriers in both stomach and vagina
Zhang, T., Huo, Z., Ma, J., He, C. & Zhong, G., May 1 2019, In: Infection and immunity. 87, 5, e00844-18.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
TIM-4 inhibits NLRP3 inflammasome via the LKB1/AMPKA pathway in macrophages
Liu, W., Bai, F., Wang, H., Liang, Y., Du, X., Liu, C., Cai, D., Peng, J., Zhong, G., Liang, X., Ma, C. & Gao, L., Aug 15 2019, In: Journal of Immunology. 203, 4, p. 990-1000 11 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
2018
2017: beginning of a new era for Chlamydia research in China and the rest of the world
Fan, H. & Zhong, G., Jan 2018, In: Microbes and Infection. 20, 1, p. 5-8 4 p.Research output: Contribution to journal › Article › peer-review
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Advances and obstacles in the genetic dissection of chlamydial virulence
Brothwell, J. A., Muramatsu, M. K., Zhong, G. & Nelson, D. E., 2018, Current Topics in Microbiology and Immunology. Springer Verlag, p. 133-158 26 p. (Current Topics in Microbiology and Immunology; vol. 412).Research output: Chapter in Book/Report/Conference proceeding › Chapter
5 Scopus citations -
Chlamydia Spreading from the Genital Tract to the Gastrointestinal Tract – A Two-Hit Hypothesis
Zhong, G., Jul 2018, In: Trends in Microbiology. 26, 7, p. 611-623 13 p.Research output: Contribution to journal › Review article › peer-review
18 Scopus citations -
Nonpathogenic colonization with Chlamydia in the gastrointestinal tract as oral vaccination for inducing transmucosal protection
Wang, L., Zhu, C., Zhang, T., Tian, Q., Zhang, N., Morrison, S., Morrison, R., Xue, M. & Zhong, G., Feb 1 2018, In: Infection and immunity. 86, 2, e00630-17.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
Oral Chlamydia vaccination induces transmucosal protection in the airway
Zhu, C., Lin, H., Tang, L., Chen, J., Wu, Y. & Zhong, G., Apr 12 2018, In: Vaccine. 36, 16, p. 2061-2068 8 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
The genital tract virulence factor pGP3 is essential for Chlamydia muridarum colonization in the gastrointestinal tract
Shao, L., Zhang, T., Melero, J., Huang, Y., Liu, Y., Liu, Q., He, C., Nelson, D. E. & Zhong, G., Jan 1 2018, In: Infection and immunity. 86, 1, e00429-17.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
Transcervical inoculation with Chlamydia trachomatis induces infertility in HLA-DR4 transgenic and wild-type mice
Pal, S., Tifrea, D. F., Zhong, G. & de la Maza, L. M., Jan 1 2018, In: Infection and immunity. 86, 1, e00722-17.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
2017
Chlamydial lipoproteins stimulate toll-like receptors 1/2 mediated inflammatory responses through MyD88-dependent pathway
Wang, Y., Liu, Q., Chen, D., Guan, J., Ma, L., Zhong, G., Shu, H. & Wu, X., Jan 26 2017, In: Frontiers in Microbiology. 8, JAN, 78.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Chlamydial Plasmid-Dependent Pathogenicity
Zhong, G., Feb 1 2017, In: Trends in Microbiology. 25, 2, p. 141-152 12 p.Research output: Contribution to journal › Review article › peer-review
41 Scopus citations -
Chlamydial protease-like activity factor mediated protection against C. trachomatis in guinea pigs
Wali, S., Gupta, R., Yu, J. J., Lanka, G. K. K., Chambers, J. P., Guentzel, M. N., Zhong, G., Murthy, A. K. & Arulanandam, B. P., May 1 2017, In: Immunology and Cell Biology. 95, 5, p. 454-460 7 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Chlamydia muridarum with mutations in chromosomal genes tc0237 and/or tc0668 is deficient in colonizing the mouse gastrointestinal tract
Shao, L., Zhang, T., Liu, Q., Wang, J. & Zhong, G., Aug 1 2017, In: Infection and immunity. 85, 8, e00321-17.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
CPAF selectively degrades chlamydial T cell antigens for inhibiting antigen presentation
Zhang, Y., Zhong, G., Cai, H., Chen, S., Sun, D., Zhang, D. & He, Y., Nov 2017, In: Journal of Infection in Developing Countries. 11, 11, p. 868-875 8 p.Research output: Contribution to journal › Article › peer-review
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IL-6-mediated signaling pathways limit Chlamydia muridarum infection and exacerbate its pathogenicity in the mouse genital tract
Sun, X., Tian, Q., Wang, L., Xue, M. & Zhong, G., Nov 2017, In: Microbes and Infection. 19, 11, p. 536-545 10 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
The cryptic plasmid is more important for Chlamydia muridarum to colonize the mouse gastrointestinal tract than to infect the genital tract
Shao, L., Melero, J., Zhang, N., Arulanandam, B., Baseman, J., Liu, Q. & Zhong, G., May 2017, In: PloS one. 12, 5, e0177691.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
Update on Chlamydia trachomatis vaccinology
De La Maza, L. M., Zhong, G. & Brunham, R. C., Apr 2017, In: Clinical and Vaccine Immunology. 24, 4, 0054316.Research output: Contribution to journal › Review article › peer-review
41 Scopus citations -
Uterotubal junction prevents chlamydial ascension via innate immunity
Zhang, Y., Shao, L., Li, X. & Zhong, G., Aug 2017, In: PloS one. 12, 8, e0183189.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
2016
An optimized, fast-to-perform mouse lung infection model with the human pathogen Chlamydia trachomatis for in vivo screening of antibiotics, vaccine candidates and modified host-pathogen interactions
Dutow, P., Wask, L., Bothe, M., Fehlhaber, B., Laudeley, R., Rheinheimer, C., Yang, Z., Zhong, G., Glage, S. & Klos, A., Mar 1 2016, In: Pathogens and disease. 74, 2Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Guinea pig genital tract lipidome reveals in vivo and in vitro regulation of phosphatidylcholine 16:0/18:1 and contribution to Chlamydia trachomatis serovar D infectivity
Wali, S., Gupta, R., Yu, J. J., Mfuh, A., Gao, X., Guentzel, M. N., Chambers, J. P., Bakar, S. A., Zhong, G. & Arulanandam, B. P., Apr 1 2016, In: Metabolomics. 12, 4, 74.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
IgA modulates respiratory dysfunction as a sequela to pulmonary chlamydial infection as neonates
Lanka, G. K. K., Yu, J. J., Gong, S., Gupta, R., Mustafa, S. B., Murthy, A. K., Zhong, G., Chambers, J. P., Guentzel, M. N. & Arulanandam, B. P., Apr 1 2016, In: Pathogens and disease. 74, 3Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Intravenous inoculation with chlamydia muridarum leads to a long-lasting infection restricted to the gastrointestinal tract
Dai, J., Zhang, T., Wang, L., Shao, L., Zhu, C., Zhang, Y., Failor, C., Schenken, R., Baseman, J., He, C. & Zhong, G., 2016, In: Infection and immunity. 84, 8, p. 2382-2388 7 p.Research output: Contribution to journal › Article › peer-review
23 Scopus citations -
Neutralizing antichlamydial activity of complement by chlamydia-secreted protease CPAF
Yang, Z., Tang, L., Zhou, Z. & Zhong, G., Nov 1 2016, In: Microbes and Infection. 18, 11, p. 669-674 6 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
Small molecule inhibition of Rab7 impairs B cell class switching and plasma cell survival to dampen the autoantibody response in murine lupus
Lam, T., Kulp, D. V., Wang, R., Lou, Z., Taylor, J., Rivera, C. E., Yan, H., Zhang, Q., Wang, Z., Zan, H., Ivanov, D. N., Zhong, G., Casali, P. & Xu, Z., Nov 15 2016, In: Journal of Immunology. 197, 10, p. 3792-3805 14 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
The Chlamydia muridarum organisms fail to auto-inoculate the mouse genital tract after colonization in the gastrointestinal tract for 70 days
Wang, L., Zhang, Q., Zhang, T., Zhang, Y., Zhu, C., Sun, X., Zhang, N., Xue, M. & Zhong, G., May 1 2016, In: PloS one. 11, 5, e0155880.Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
The chromosome-encoded hypothetical protein TC0668 is an upper genital tract pathogenicity factor of Chlamydia muridarum
Conrad, T. A., Gong, S., Yang, Z., Matulich, P., Keck, J., Beltrami, N., Chen, C., Zhou, Z., Dai, J. & Zhong, G., 2016, In: Infection and immunity. 84, 2, p. 467-479 13 p.Research output: Contribution to journal › Article › peer-review
35 Scopus citations -
2015
Characterization of CPAF critical residues and secretion during Chlamydia trachomatis infection
Yang, Z., Tang, L., Sun, X., Chai, J. & Zhong, G., 2015, In: Infection and immunity. 83, 6, p. 2234-2241 8 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Chlamydial plasmid-encoded virulence factor Pgp3 neutralizes the antichlamydial activity of human cathelicidin LL-37
Hou, S., Dong, X., Yang, Z., Li, Z., Liu, Q. & Zhong, G., 2015, In: Infection and immunity. 83, 12, p. 4701-4709 9 p.Research output: Contribution to journal › Article › peer-review
29 Scopus citations -
Chlamydia muridarum induction of glandular duct dilation in mice
Sun, X., Yang, Z., Zhang, H., Dai, J., Chen, J., Tang, L., Rippentrop, S., Xue, M., Zhong, G. & Wu, G., 2015, In: Infection and immunity. 83, 6, p. 2327-2337 11 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Chlamydia-secreted protease CPAF degrades host antimicrobial peptides
Tang, L., Chen, J., Zhou, Z., Yu, P., Yang, Z. & Zhong, G., 2015, In: Microbes and Infection. 17, 6, p. 402-408 7 p.Research output: Contribution to journal › Article › peer-review
29 Scopus citations -
Effect of pH on cleavage of glycogen by vaginal enzymes
Spear, G. T., McKenna, M., Landay, A. L., Makinde, H., Hamaker, B., French, A. L., Lee, B. H. & Zhong, G., Jul 14 2015, In: PloS one. 10, 7Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
Identification of plasmid-free chlamydia muridarum organisms using a pgp3 detection-based immunofluorescence assay
Chen, C., Zhong, G., Ren, L., Lu, C., Li, Z. & Wu, Y., 2015, In: Journal of Microbiology and Biotechnology. 25, 10, p. 1621-1628 8 p., A006.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Infection with Chlamydia pneumoniae as a cause of coronary heart disease: The hypothesis is still untested
Grayston, J. T., Belland, R. J., Byrne, G. I., Kuo, C. C., Schachter, J., Stamm, W. E. & Zhong, G., Feb 1 2015, In: Pathogens and disease. 73, 1Research output: Contribution to journal › Comment/debate › peer-review
19 Scopus citations -
Intrauterine infection with plasmid-free Chlamydia muridarum reveals a critical role of the plasmid in chlamydial ascension and establishes a model for evaluating plasmid-independent pathogenicity
Chen, J., Yang, Z., Sun, X., Tang, L., Ding, Y., Xue, M., Zhou, Z., Baseman, J. & Zhong, G., 2015, In: Infection and immunity. 83, 6, p. 2583-2592 10 p.Research output: Contribution to journal › Article › peer-review
16 Scopus citations