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• 2020

  Attenuation of NAD[P]H:quinone oxidoreductase 1 aggravates prostate cancer and tumor cell plasticity through enhanced TGFβ signaling

  Thapa, D., Huang, S. B., Muñoz, A. R., Yang, X., Bedolla, R. G., Hung, C. N., Chen, C. L., Huang, T. H. M., Liss, M. A., Reddick, R. L., Miyamoto, H., Kumar, A. P. & Ghosh, R., Dec 1 2020, In: Communications Biology. 3, 1, 12.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • prostatic neoplasms
  • Cell Plasticity
  • NAD(P)H dehydrogenase (quinone)
  • quinone
  • Oxidative stress
  2 Scopus citations

• Comparative evaluation of network features for the prediction of breast cancer metastasis

  Adnan, N., Liu, Z., Huang, T. H. M. & Ruan, J., Apr 3 2020, In: BMC Medical Genomics. 13, 40.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Breast Neoplasms
  • Neoplasm Metastasis
  • Genes
  • Gene Expression
  • Protein Interaction Maps
  2 Scopus citations

• Detection of DNA methylation by MeDIP and MBDCap assays: An overview of techniques

  Hsu, H. K., Weng, Y. I., Hsu, P. Y., Huang, T. H. M. & Huang, Y. W., 2020, Methods in Molecular Biology. Humana Press, p. 225-234 10 p. (Methods in Molecular Biology; vol. 2102).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • DNA Methylation
  • Immunoprecipitation
  • Genome
  • Epigenomics
  • Methyl CpG Binding Domain
  1 Scopus citations

• Enhancer reprogramming driven by high-order assemblies of transcription factors promotes phenotypic plasticity and breast cancer endocrine resistance

  Bi, M., Zhang, Z., Jiang, Y. Z., Xue, P., Wang, H., Lai, Z., Fu, X., De Angelis, C., Gong, Y., Gao, Z., Ruan, J., Jin, V. X., Marangoni, E., Montaudon, E., Glass, C. K., Li, W., Huang, T. H. M., Shao, Z. M., Schiff, R., Chen, L. & 1 others, Liu, Z., Jun 1 2020, In: Nature Cell Biology. 22, 6, p. 701-715 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Physiological Adaptation
  • Transcription Factors
  • Breast Neoplasms
  • Heterografts
  • GATA3 Transcription Factor
  5 Scopus citations

• ERα-related chromothripsis enhances concordant gene transcription on chromosome 17q11.1-q24.1 in luminal breast cancer

  Lin, C. L., Tan, X., Chen, M., Kusi, M., Hung, C. N., Chou, C. W., Hsu, Y. T., Wang, C. M., Kirma, N., Chen, C. L., Lin, C. H., Lathrop, K. I., Elledge, R., Kaklamani, V. G., Mitsuya, K. & Huang, T. H. M., May 14 2020, In: BMC Medical Genomics. 13, 1, 69.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Chromothripsis
  • Chromosomes
  • Breast Neoplasms
  • Genes
  • Neoplasms

• Menin and menin-associated proteins coregulate cancer energy metabolism

  Chou, C. W., Tan, X., Hung, C. N., Lieberman, B., Chen, M., Kusi, M., Mitsuya, K., Lin, C. L., Morita, M., Liu, Z., Chen, C. L. & Huang, T. H. M., Sep 2020, In: Cancers. 12, 9, p. 1-21 21 p., 2715.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Energy Metabolism
  • Oxidative Phosphorylation
  • Glycolysis
  • Proteins
  • Neoplasms

• PAI-1-Dependent Inactivation of SMAD4-Modulated Junction and Adhesion Complex in Obese Endometrial Cancer

  Lin, L. L., Kost, E. R., Lin, C. L., Valente, P., Wang, C. M., Kolonin, M. G., Daquinag, A. C., Tan, X., Lucio, N., Hung, C. N., Wang, C. P., Kirma, N. B. & Huang, T. H. M., Oct 13 2020, In: Cell Reports. 33, 2, 108253.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Plasminogen Activator Inhibitor 1
  • Endometrial Neoplasms
  • Stromal Cells
  • Cell Communication
  • Adhesion

• Single-cell proteomic profiling identifies combined AXL and JAK1 inhibition as a novel therapeutic strategy for lung cancer

  Taverna, J. A., Hung, C. N., DeArmond, D. T., Chen, M., Lin, C. L., Osmulski, P. A., Gaczynska, M. E., Wang, C. M., Lucio, N. D., Chou, C. W., Chen, C. L., Nazarullah, A., Lampkin, S. R., Qiu, L., Bearss, D. J., Warner, S., Whatcott, C. J., Mouritsen, L., Wade, M., Weitman, S. & 4 others, Mesa, R. A., Kirma, N. B., Chao, W. T. & Huang, T. H. M., Apr 1 2020, In: Cancer Research. 80, 7, p. 1551-1563 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Proteomics
  • Lung Neoplasms
  • TP-0903
  • Neoplasms
  • single cell proteins
  2 Scopus citations
• 2019

  Aberrant enhancer hypomethylation contributes to hepatic carcinogenesis through global transcriptional reprogramming

  Xiong, L., Wu, F., Wu, Q., Xu, L., Cheung, O. K., Kang, W., Mok, M. T., Szeto, L. L. M., Lun, C. Y., Lung, R. W., Zhang, J., Yu, K. H., Lee, S. D., Huang, G., Wang, C. M., Liu, J., Yu, Z., Yu, D. Y., Chou, J. L., Huang, W. H. & 10 others, Feng, B., Cheung, Y. S., Lai, P. B., Tan, P., Wong, N., Chan, M. W., Huang, T. H., Yip, K. Y., Cheng, A. S. & To, K. F., Dec 1 2019, In: Nature communications. 10, 1, 335.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • CCAAT-Enhancer-Binding Protein-beta
  • proteins
  • Carcinogenesis
  • Liver
  • Hepatocellular Carcinoma
  16 Scopus citations

• Adipokines deregulate cellular communication via epigenetic repression of gap junction loci in obese endometrial cancer

  Polusani, S. R., Huang, Y. W., Huang, G., Chen, C. W., Wang, C. M., Lin, L. L., Osmulski, P., Lucio, N. D., Liu, L., Hsu, Y. T., Zhou, Y., Lin, C. L., Aguilera-Barrantes, I., Valente, P. T., Kost, E. R., Chen, C. L., Shim, E. Y., Lee, S. E., Ruan, J., Gaczynska, M. E. & 7 others, Yan, P., Goodfellow, P. J., Mutch, D. G., Jin, V. X., Nicholson, B. J., Huang, T. H. M. & Kirma, N. B., Jan 1 2019, In: Cancer Research. 79, 1, p. 196-208 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Epigenetic Repression
  • Adipokines
  • Gap Junctions
  • Endometrial Neoplasms
  • Communication
  4 Scopus citations

• A Non-canonical Role of YAP/TEAD Is Required for Activation of Estrogen-Regulated Enhancers in Breast Cancer

  Zhu, C., Li, L., Zhang, Z., Bi, M., Wang, H., Su, W., Hernandez, K., Liu, P., Chen, J., Chen, M., Huang, T. H. M., Chen, L. & Liu, Z., Aug 22 2019, In: Molecular Cell. 75, 4, p. 791-806.e8

  Research output: Contribution to journal › Article › peer-review

  • Estrogens
  • Breast Neoplasms
  • Organ Size
  • Growth
  • Carcinogenesis
  18 Scopus citations

• A novel algorithm for network-based prediction of cancer recurrence

  Ruan, J., Jahid, M. J., Gu, F., Lei, C., Huang, Y. W., Hsu, Y. T., Mutch, D. G., Chen, C. L., Kirma, N. B. & Huang, T. H. M., Jan 2019, In: Genomics. 111, 1, p. 17-23 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Recurrence
  • Epigenomics
  • Genes
  • Neoplasms
  • Protein Interaction Maps
  4 Scopus citations

• SOX11 hypermethylation as a tumor biomarker in endometrial cancer

  Shan, T., Uyar, D. S., Wang, L. S., Mutch, D. G., Huang, T. H. M., Rader, J. S., Sheng, X. & Huang, Y. W., Jul 2019, In: Biochimie. 162, p. 8-14 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Methylation
  • Endometrial Neoplasms
  • Tumor Biomarkers
  • DNA Methylation
  • hydrogen sulfite
  2 Scopus citations

• Spatial EGFR dynamics and metastatic phenotypes modulated by upregulated Ephb2 and Src pathways in advanced prostate cancer

  Liu, Y. L., Horning, A. M., Lieberman, B., Kim, M., Lin, C. K., Hung, C. N., Chou, C. W., Wang, C. M., Lin, C. L., Kirma, N. B., Liss, M. A., Vasisht, R., Perillo, E. P., Blocher, K., Horng, H., Taverna, J. A., Ruan, J., Yankeelov, T. E., Dunn, A. K., Huang, T. H. M. & 2 others, Yeh, H. C. & Chen, C. L., Dec 2019, In: Cancers. 11, 12, 1910.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • ErbB Receptors
  • Prostatic Neoplasms
  • Phenotype
  • PC-3 Cells
  • Dasatinib
  2 Scopus citations
• 2018

  BRCA1 interacting protein COBRA1 facilitates adaptation to castrate-resistant growth conditions

  Yun, H., Bedolla, R., Horning, A., Li, R., Chiang, H. C., Huang, T. H., Reddick, R., Olumi, A. F., Ghosh, R. & Kumar, A. P., Jul 2018, In: International journal of molecular sciences. 19, 7, 2104.

  Research output: Contribution to journal › Article › peer-review

  • Androgens
  • BRCA1 Protein
  • Cell proliferation
  • Cells
  • Proteins
  3 Scopus citations

• Cross-talk among writers, readers, and erasers of m⁶A regulates cancer growth and progression

  Panneerdoss, S., Eedunuri, V. K., Yadav, P., Timilsina, S., Rajamanickam, S., Viswanadhapalli, S., Abdelfattah, N., Onyeagucha, B. C., Cui, X., Lai, Z., Mohammad, T. A., Gupta, Y. K., Huang, T. H. M., Huang, Y., Chen, Y. & Rao, M. K., Oct 3 2018, In: Science Advances. 4, 10, eaar8263.

  Research output: Contribution to journal › Article › peer-review

  • Methyltransferases
  • Growth
  • Genes
  • N(6)-methyladenosine
  • Neoplasms
  64 Scopus citations

• Distinct methylation profile of mucinous ovarian carcinoma reveals susceptibility to proteasome inhibitors

  Liew, P. L., Huang, R. L., Weng, Y. C., Fang, C. L., Hui-Ming Huang, T. & Lai, H. C., Jul 15 2018, In: International Journal of Cancer. 143, 2, p. 355-367 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mucinous Adenocarcinoma
  • Proteasome Inhibitors
  • Ovarian Epithelial Carcinoma
  • Methylation
  • Gastrointestinal Neoplasms
  2 Scopus citations

• Diverse AR-V7 cistromes in castration-resistant prostate cancer are governed by HoxB13

  Chen, Z., Wu, D., Thomas-Ahner, J. M., Lu, C., Zhao, P., Zhang, Q., Geraghty, C., Yan, P. S., Hankey, W., Sunkel, B., Cheng, X., Antonarakis, E. S., Wang, Q. E., Liu, Z., Huang, T. H. M., Jin, V. X., Clinton, S. K., Luo, J., Huang, J. & Wang, Q., Jun 26 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 26, p. 6810-6815 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Castration
  • Androgen Receptors
  • Prostatic Neoplasms
  • Circulating Neoplastic Cells
  • Oncogenes
  36 Scopus citations

• miR-137 is a tumor suppressor in endometrial cancer and is repressed by DNA hypermethylation

  Zhang, W., Chen, J. H., Shan, T., Aguilera-Barrantes, I., Wang, L. S., Huang, T. H. M., Rader, J. S., Sheng, X. & Huang, Y. W., Nov 1 2018, In: Laboratory Investigation. 98, 11, p. 1397-1407 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Endometrial Neoplasms
  • DNA
  • MicroRNAs
  • Neoplasms
  • CpG Islands
  17 Scopus citations

• Single-Cell RNA-seq reveals a subpopulation of prostate cancer cells with enhanced cell-Cycle–Related transcription and attenuated androgen response

  Horning, A. M., Wang, Y., Lin, C. K., Louie, A. D., Jadhav, R. R., Hung, C. N., Wang, C. M., Lin, C. L., Kirma, N. B., Liss, M. A., Kumar, A. P., Sun, L. Z., Liu, Z., Chao, W. T., Wang, Q., Jin, V. X., Chen, C. L. & Huang, T. H. M., Feb 15 2018, In: Cancer Research. 78, 4, p. 853-864 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Androgens
  • Prostatic Neoplasms
  • RNA
  • Genes
  • Atlases
  28 Scopus citations

• Suppression of ribosomal protein RPS6KB1 by Nexrutine increases sensitivity of prostate tumors to radiation

  Hussain, S. S., Huang, S. B., Bedolla, R. G., Rivas, P., Basler, J. W., Swanson, G. P., Hui-Ming Huang, T., Narayanasamy, G., Papanikolaou, N., Miyamoto, H., Yeh, I. T., Reddick, R. L., Pollock, B. H., Ghosh, R. & Kumar, A. P., Oct 1 2018, In: Cancer Letters. 433, p. 232-241 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Nexrutine
  • Ribosomal Proteins
  • Prostate
  • Prostatic Neoplasms
  • Radiation
  5 Scopus citations

• Tamoxifen resistance in breast cancer is regulated by the EZH2–ERa–GREB1 transcriptional axis

  Wu, Y., Zhang, Z., Cenciarini, M. E., Proietti, C. J., Amasino, M., Hong, T., Yang, M., Liao, Y., Chiang, H. C., Kaklamani, V. G., Jeselsohn, R., Vadlamudi, R. K., Huang, T. H. M., Li, R., De Angelis, C., Fu, X., Elizalde, P. V., Schiff, R., Brown, M. & Xu, K., Feb 1 2018, In: Cancer Research. 78, 3, p. 671-684 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Tamoxifen
  • Epigenomics
  • Estrogen Receptors
  • Breast Neoplasms
  • Estrogen Receptor Modulators
  32 Scopus citations
• 2017

  Cellular cholesterol regulates monocyte deformation

  Saha, A. K., Dallo, S. F., Detmar, A. L., Osmulski, P., Gaczynska, M., Huang, T. H. M. & Ramasubramanian, A. K., 2017, In: Journal of Biomechanics. 52, p. 83-88 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Cholesterol
  • Monocytes
  • Formability
  • Macrophages
  • Phosphorylation
  6 Scopus citations

• Cholesterol Regulates Monocyte Rolling through CD44 Distribution

  Saha, A. K., Osmulski, P., Dallo, S. F., Gaczynska, M., Huang, T. H. M. & Ramasubramanian, A. K., Apr 11 2017, In: Biophysical Journal. 112, 7, p. 1481-1488 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Monocytes
  • Cholesterol
  • E-Selectin
  • adhesion receptor
  • Atherosclerosis
  7 Scopus citations

• Complete Transcriptome RNA-Seq

  Miller, D. F. B., Yan, P., Fang, F., Buechlein, A., Kroll, K., Frankhouser, D., Stump, C., Stump, P., Ford, J. B., Tang, H., Michaels, S., Matei, D., Huang, T. H., Chien, J., Liu, Y., Rusch, D. B. & Nephew, K. P., 2017, Methods in Molecular Biology. Humana Press, p. 141-162 22 p. (Methods in Molecular Biology; vol. 1513).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Transcriptome
  • RNA
  • Ribosomal RNA
  • Gene Expression
  • Cations
  1 Scopus citations

• Computational methods and correlation of Exon-skipping events with splicing, transcription, and epigenetic factors

  Wang, J., Ye, Z., Huang, T. H., Shi, H. & Jin, V. X., 2017, Methods in Molecular Biology. Humana Press, p. 163-170 8 p. (Methods in Molecular Biology; vol. 1513).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • RNA Splicing Factors
  • Epigenomics
  • Exons
  • Transcription Factors
  • RNA
  6 Scopus citations

• Deep sequencing of HPV E6/E7 genes reveals loss of genotypic diversity and gain of clonal dominance in high-grade intraepithelial lesions of the cervix

  Shen-Gunther, J., Wang, Y., Lai, Z., Poage, G. M., Perez, L. & Huang, T. H. M., Mar 14 2017, In: BMC genomics. 18, 1, 231.

  Research output: Contribution to journal › Article › peer-review

  • High-Throughput Nucleotide Sequencing
  • Cervix Uteri
  • Genotype
  • Genes
  • Cell Biology
  13 Scopus citations

• DNA methylation targets influenced by bisphenol A and/or genistein are associated with survival outcomes in breast cancer patients

  Jadhav, R. R., Santucci-Pereira, J., Wang, Y. V., Liu, J., Nguyen, T. D., Wang, J., Jenkins, S., Russo, J., Huang, T. H. M., Jin, V. X. & Lamartiniere, C. A., May 15 2017, In: Genes. 8, 5, 144.

  Research output: Contribution to journal › Article › peer-review

  • bisphenol A
  • Genistein
  • DNA Methylation
  • Breast Neoplasms
  • Survival
  17 Scopus citations

• EGFR-dependent regulated intramembrane proteolysis of EpCAM - Response

  Hsu, Y. T., Osmulski, P., Wang, Y., Huang, Y. W., Liu, L., Ruan, J., Jin, V. X., Kirma, N. B., Gaczynska, M. E. & Huang, T. H. M., 2017, In: Cancer Research. 77, 7, p. 1777 1 p.

  Research output: Contribution to journal › Letter › peer-review
  1 Scopus citations

• Integrated epigenomics analysis reveals a DNA methylation panel for endometrial cancer detection using cervical scrapings

  Huang, R. L., Su, P. H., Liao, Y. P., Wu, T. I., Hsu, Y. T., Lin, W. Y., Wang, H. C., Weng, Y. C., Ou, Y. C., Huang, T. H. M. & Lai, H. C., Jan 1 2017, In: Clinical Cancer Research. 23, 1, p. 263-272 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Endometrial Neoplasms
  • DNA Methylation
  • Epigenomics
  • Genes
  • Methylation
  31 Scopus citations

• Integration of DNA methylation and gene transcription across nineteen cell types reveals cell type-specific and genomic region-dependent regulatory patterns

  Tang, B., Zhou, Y., Wang, C. M., Huang, T. H. M. & Jin, V. X., Dec 1 2017, In: Scientific reports. 7, 1, 3626.

  Research output: Contribution to journal › Article › peer-review

  • Nucleic Acid Regulatory Sequences
  • DNA Methylation
  • Genes
  • Tumor Suppressor Genes
  • Methylation
  13 Scopus citations

• Integrative analysis identifies targetable CREB1/FoxA1 transcriptional co-regulation as a predictor of prostate cancer recurrence

  Sunkel, B., Wu, D., Chen, Z., Wang, C. M., Liu, X., Ye, Z., Horning, A. M., Liu, J., Mahalingam, D., Lopez-Nicora, H., Lin, C. L., Goodfellow, P. J., Clinton, S. K., Jin, V. X., Chen, C. L., Huang, T. H. M. & Wang, Q., Jun 20 2017, In: Nucleic acids research. 45, 11, p. 6993 1 p.

  Research output: Contribution to journal › Article › peer-review
  3 Scopus citations

• JAK2V617F influences epigenomic changes in myeloproliferative neoplasms

  Chen, C. C., Chiu, C. C., Lee, K. D., Hsu, C. C., Chen, H. C., Huang, T. H. M., Hsiao, S. H. & Leu, Y. W., Dec 16 2017, In: Biochemical and Biophysical Research Communications. 494, 3-4, p. 470-476 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Enhancer of Zeste Homolog 2 Protein
  • STAT3 Transcription Factor
  • Epigenomics
  • Methylation
  • Chromatin
  1 Scopus citations

• Promoter methylation modulates indoleamine 2,3-dioxygenase 1 induction by activated T cells in human breast cancers

  Noonepalle, S. K., Gu, F., Lee, E. J., Choi, J. H., Han, Q., Kim, J., Ouzounova, M., Shull, A. Y., Pei, L., Hsu, P. Y., Kolhe, R., Shi, F., Choi, J., Chiou, K., Huang, T. H. M., Korkaya, H., Deng, L., Xin, H. B., Huang, S., Thangaraju, M. & 5 others, Sreekumar, A., Ambs, S., Tang, S. C., Munn, D. H. & Shi, H., Apr 2017, In: Cancer Immunology Research. 5, 4, p. 330-344 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Indoleamine-Pyrrole 2,3,-Dioxygenase
  • Methylation
  • Breast Neoplasms
  • Triple Negative Breast Neoplasms
  • T-Lymphocytes
  13 Scopus citations

• Reprimo, a potential p53-dependent tumor suppressor gene, is frequently hypermethylated in estrogen receptor α-positive breast cancer

  Buchegger, K., Riquelme, I., Viscarra, T., Ili, C., Brebi, P., Huang, T. H. M. & Roa, J. C., Aug 15 2017, In: International journal of molecular sciences. 18, 8, 1525.

  Research output: Contribution to journal › Article › peer-review

  • tumor suppressor genes
  • Estrogens
  • estrogens
  • DNA Methylation
  • methylation
  1 Scopus citations

• START: A system for flexible analysis of hundreds of genomic signal tracks in few lines of SQL-like queries

  Zhu, X., Zhang, Q., Ho, E. D., Yu, K. H. O., Liu, C., Huang, T. H., Cheng, A. S. L., Kao, B., Lo, E. & Yip, K. Y., Sep 22 2017, In: BMC genomics. 18, 1, 749.

  Research output: Contribution to journal › Article › peer-review

  • Language
  • Galaxies
  • Boidae
  • DNA Methylation
  • Information Storage and Retrieval
  4 Scopus citations
• 2016

  Crosstalk between RON and androgen receptor signaling in the development of castration resistant prostate cancer

  Batth, I., Yun, H., Hussain, S., Meng, P., Osumulski, P., Huang, T. H. M., Bedolla, R., Profit, A., Reddick, R. & Kumar, A., Mar 22 2016, In: Oncotarget. 7, 12, p. 14048-14063 16 p.

  Research output: Contribution to journal › Article › peer-review

  • rice bran saccharide
  • Castration
  • Androgen Receptors
  • Androgens
  • Prostatic Neoplasms
  9 Scopus citations

• Differential network analysis reveals the genome-wide landscape of estrogen receptor modulation in hormonal cancers

  Hsiao, T. H., Chiu, Y. C., Hsu, P. Y., Lu, T. P., Lai, L. C., Tsai, M. H., Huang, T. H. M., Chuang, E. Y. & Chen, Y., Mar 14 2016, In: Scientific reports. 6, 23035.

  Research output: Contribution to journal › Article › peer-review

  • Estrogen Receptors
  • Genome
  • Genes
  • Neoplasms
  • Datasets
  18 Scopus citations

• EpCAM-regulated transcription exerts influences on nanomechanical properties of endometrial cancer cells that promote epithelial-to-mesenchymal transition

  Hsu, Y. T., Osmulski, P., Wang, Y., Huang, Y. W., Liu, L., Ruan, J., Jin, V. X., Kirma, N. B., Gaczynska, M. E. & Huang, T. H. M., Nov 1 2016, In: Cancer Research. 76, 21, p. 6171-6182 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Epithelial-Mesenchymal Transition
  • Endometrial Neoplasms
  • Epithelial Cells
  • Epidermal Growth Factor
  • Adhesiveness
  24 Scopus citations

• Genome-wide analysis reveals positional-nucleosome-oriented binding pattern of pioneer factor FOXA1

  Ye, Z., Chen, Z., Sunkel, B., Frietze, S., Huang, T. H. M., Wang, Q. & Jin, V. X., Sep 19 2016, In: Nucleic acids research. 44, 16, p. 7540-7554 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Nucleosomes
  • Chromatin
  • Genome
  • Histones
  • DNA
  8 Scopus citations

• Integrative analysis identifies targetable CREB1/FoxA1 transcriptional co-regulation as a predictor of prostate cancer recurrence

  Sunkel, B., Wu, D., Chen, Z., Wang, C. M., Liu, X., Ye, Z., Horning, A. M., Liu, J., Mahalingam, D., Lopez-Nicora, H., Lin, C. L., Goodfellow, P. J., Clinton, S. K., Jin, V. X., Chen, C. L., Huang, T. H. M. & Wang, Q., May 19 2016, In: Nucleic acids research. 44, 9, p. 4105-4122 18 p.

  Research output: Contribution to journal › Article › peer-review

  • Prostatic Neoplasms
  • Recurrence
  • Transcriptome
  • Transcription Factors
  • Circulating Neoplastic Cells
  17 Scopus citations

• Methyl-binding DNA capture sequencing for patient tissues

  Jadhav, R. R., Wang, Y. V., Hsu, Y. T., Liu, J., Garcia, D., Lai, Z., Huang, T. H. M. & Jin, V. X., Oct 31 2016, In: Journal of Visualized Experiments. 2016, 116, e54131.

  Research output: Contribution to journal › Article › peer-review

  • Methylation
  • DNA
  • DNA Sequence Analysis
  • Tissue
  • Bioinformatics
  1 Scopus citations

• MiR-16 mediates trastuzumab and lapatinib response in ErbB-2-positive breast and gastric cancer via its novel targets CCNJ and FUBP1

  Venturutti, L., Cordo Russo, R. I., Rivas, M. A., Mercogliano, M. F., Izzo, F., Oakley, R. H., Pereyra, M. G., De Martino, M., Proietti, C. J., Yankilevich, P., Roa, J. C., Guzmán, P., Cortese, E., Allemand, D. H., Huang, T. H., Charreau, E. H., Cidlowski, J. A., Schillaci, R. & Elizalde, P. V., Dec 1 2016, In: Oncogene. 35, 48, p. 6189-6202 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Lapatinib
  • Trastuzumab
  • Stomach Neoplasms
  • Carrier Proteins
  • Breast Neoplasms
  47 Scopus citations

• Molecular Pap smear: HPV genotype and DNA methylation of ADCY8, CDH8, and ZNF582 as an integrated biomarker for high-grade cervical cytology

  Shen-Gunther, J., Wang, C. M., Poage, G. M., Lin, C. L., Perez, L., Banks, N. A. & Huang, T. H. M., Sep 13 2016, In: Clinical Epigenetics. 8, 1, 96.

  Research output: Contribution to journal › Article › peer-review

  • Squamous Intraepithelial Lesions of the Cervix
  • Papanicolaou Test
  • Zinc Fingers
  • Cadherins
  • Adenylyl Cyclases
  19 Scopus citations

• NF-κB-HOTAIR axis links DNA damage response, chemoresistance and cellular senescence in ovarian cancer

  Özeş, A. R., Miller, D. F., Özeş, O. N., Fang, F., Liu, Y., Matei, D., Huang, T. & Nephew, K. P., Oct 13 2016, In: Oncogene. 35, 41, p. 5350-5361 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Antisense RNA
  • Cellular Senescence
  • NF-kappa B
  • Ovarian Neoplasms
  • DNA Damage
  136 Scopus citations

• Reprimo as a modulator of cell migration and invasion in the MDA-MB-231 breast cancer cell line

  Buchegger, K., Ili, C., Riquelme, I., Letelier, P., Corvalán, A. H., Brebi, P., Huang, T. H. M. & Roa, J. C., Jan 22 2016, In: Biological Research. 49, 1, 5.

  Research output: Contribution to journal › Article › peer-review

  • Methylation
  • breast neoplasms
  • cell movement
  • Modulators
  • Cells
  12 Scopus citations

• Roles of distal and genic methylation in the development of prostate tumorigenesis revealed by genome-wide DNA methylation analysis

  Wang, Y., Jadhav, R. R., Liu, J., Wilson, D., Chen, Y., Thompson, I. M., Troyer, D. A., Hernandez, J., Shi, H., Leach, R. J., Huang, T. H. M. & Jin, V. X., 2016, In: Scientific reports. 6, 22051.

  Research output: Contribution to journal › Article › peer-review

  • DNA Methylation
  • Methylation
  • Prostate
  • Carcinogenesis
  • Genome
  13 Scopus citations

• Spatiotemporal control of estrogen-responsive transcription in ERα-positive breast cancer cells

  Hsu, P. Y., Hsu, H. K., Hsiao, T. H., Ye, Z., Wang, E., Profit, A. L., Jatoi, I., Chen, Y., Kirma, N. B., Jin, V. X., Sharp, Z. D. & Huang, T. H. M., May 5 2016, In: Oncogene. 35, 18, p. 2379-2389 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Response Elements
  • Estrogens
  • Breast Neoplasms
  • heterochromatin-specific nonhistone chromosomal protein HP-1
  • Chromosomes
  11 Scopus citations

• TGF-β signal rewiring sustains epithelial-mesenchymal transition of circulating tumor cells in prostate cancer xenograft hosts

  Huang, G., Osmulski, P. A., Bouamar, H., Mahalingam, D., Lin, C. L., Liss, M. A., Kumar, A. P., Chen, C. L., Thompson, I. M., Sun, L. Z., Gaczynska, M. E. & Huang, T. H. M., 2016, In: Oncotarget. 7, 47, p. 77124-77137 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Circulating Neoplastic Cells
  • Castration
  • Epithelial-Mesenchymal Transition
  • Heterografts
  • Prostatic Neoplasms
  4 Scopus citations
• 2015

  Aberrant epigenetic modifications in radiation-resistant head and neck cancers

  Lin, H. Y., Huang, T. H. M. & Chan, M. W. Y., Jan 1 2015, In: Methods in Molecular Biology. 1238, p. 321-332 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Ionizing Radiation
  • Head and Neck Neoplasms
  • Epigenomics
  • Radiation
  • hydrogen sulfite