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  • Hanna E Abboud
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  • 2020

    Endothelium-specific deletion of Nox4 delays retinal vascular development and mitigates pathological angiogenesis

    Tang, X., Wang, J. J., Wang, J., Abboud, H. E., Chen, Y. & Zhang, S. X., 2020, (Accepted/In press) In: Angiogenesis.

    Research output: Contribution to journal › Article › peer-review

  • Interplay between RNA-binding protein HuR and Nox4 as a novel therapeutic target in diabetic kidney disease

    Shi, Q., Lee, D. Y., Féliers, D., Abboud, H. E., Bhat, M. A. & Gorin, Y., Jun 2020, In: Molecular Metabolism. 36, 100968.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    2 Scopus citations
  • 2019

    JC viruria is associated with reduced risk of diabetic kidney disease

    Family Investigation of Nephropathy and Diabetes (FIND Consortium), Jun 1 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 6, p. 2286-2294 9 p.

    Research output: Contribution to journal › Article › peer-review

    1 Scopus citations
  • 2018

    Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

    Flannick, J., Fuchsberger, C., Mahajan, A., Teslovich, T. M., Agarwala, V., Gaulton, K. J., Caulkins, L., Koesterer, R., Ma, C., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Tajes, J. F. & 281 others, Highland, H. M., Dupuis, J., Chines, P. S., Lindgren, C. M., Hartl, C., Jackson, A. U., Chen, H., Huyghe, J. R., van de Bunt, M., Pearson, R. D., Kumar, A., Müller-Nurasyid, M., Grarup, N., Stringham, H. M., Gamazon, E. R., Lee, J., Chen, Y., Scott, R. A., Below, J. E., Chen, P., Huang, J., Go, M. J., Stitzel, M. L., Pasko, D., Parker, S. C. J., Varga, T. V., Green, T., Beer, N. L., Day-Williams, A. G., Ferreira, T., Fingerlin, T., Horikoshi, M., Hu, C., Huh, I., Ikram, M. K., Kim, B. J., Kim, Y., Kim, Y. J., Kwon, M. S., Lee, J., Lee, S., Lin, K. H., Maxwell, T. J., Nagai, Y., Wang, X., Welch, R. P., Yoon, J., Zhang, W., Barzilai, N., Voight, B. F., Han, B. G., Jenkinson, C. P., Kuulasmaa, T., Kuusisto, J., Manning, A., Ng, M. C. Y., Palmer, N. D., Balkau, B., Stančáková, A., Abboud, H. E., Boeing, H., Giedraitis, V., Prabhakaran, D., Gottesman, O., Scott, J., Carey, J., Kwan, P., Grant, G., Smith, J. D., Neale, B. M., Purcell, S., Butterworth, A. S., Howson, J. M. M., Lee, H. M., Lu, Y., Kwak, S. H., Zhao, W., Danesh, J., Lam, V. K. L., Park, K. S., Saleheen, D., So, W. Y., Tam, C. H. T., Afzal, U., Aguilar, D., Arya, R., Aung, T., Chan, E., Navarro, C., Cheng, C. Y., Palli, D., Correa, A., Curran, J. E., Rybin, D., Farook, V. S., Fowler, S. P., Freedman, B. I., Griswold, M., Hale, D. E., Hicks, P. J., Khor, C. C., Kumar, S., Lehne, B., Thuillier, D., Lim, W. Y., Liu, J., Loh, M., Musani, S. K., Puppala, S., Scott, W. R., Yengo, L., Tan, S. T., Taylor, H. A., Thameem, F., Wilson, G., Wong, T. Y., Njølstad, P. R., Levy, J. C., Mangino, M., Bonnycastle, L. L., Schwarzmayr, T., Fadista, J., Surdulescu, G. L., Herder, C., Groves, C. J., Wieland, T., Bork-Jensen, J., Brandslund, I., Christensen, C., Koistinen, H. A., Doney, A. S. F., Kinnunen, L., Esko, T., Farmer, A. J., Hakaste, L., Hodgkiss, D., Kravic, J., Lyssenko, V., Hollensted, M., Jørgensen, M. E., Jørgensen, T., Ladenvall, C., Justesen, J. M., Käräjämäki, A., Kriebel, J., Rathmann, W., Lannfelt, L., Lauritzen, T., Narisu, N., Linneberg, A., Melander, O., Milani, L., Neville, M., Orho-Melander, M., Qi, L., Qi, Q., Roden, M., Rolandsson, O., Swift, A., Rosengren, A. H., Stirrups, K., Wood, A. R., Mihailov, E., Blancher, C., Carneiro, M. O., Maguire, J., Poplin, R., Shakir, K., Fennell, T., DePristo, M., de Angelis, M. H., Deloukas, P., Gjesing, A. P., Jun, G., Nilsson, P., Murphy, J., Onofrio, R., Thorand, B., Hansen, T., Meisinger, C., Hu, F. B., Isomaa, B., Karpe, F., Liang, L., Peters, A., Huth, C., O'Rahilly, S. P., Palmer, C. N. A., Pedersen, O., Rauramaa, R., Tuomilehto, J., Salomaa, V., Watanabe, R. M., Syvänen, A. C., Bergman, R. N., Bharadwaj, D., Bottinger, E. P., Cho, Y. S., Chandak, G. R., Chan, J. C. N., Chia, K. S., Daly, M. J., Ebrahim, S. B., Langenberg, C., Elliott, P., Jablonski, K. A., Lehman, D. M., Jia, W., Ma, R. C. W., Pollin, T. I., Sandhu, M., Tandon, N., Froguel, P., Barroso, I., Teo, Y. Y., Zeggini, E., Loos, R. J. F., Small, K. S., Ried, J. S., DeFronzo, R. A., Grallert, H., Glaser, B., Metspalu, A., Wareham, N. J., Walker, M., Banks, E., Gieger, C., Ingelsson, E., Im, H. K., Illig, T., Franks, P. W., Buck, G., Trakalo, J., Buck, D., Prokopenko, I., Mägi, R., Lind, L., Farjoun, Y., Owen, K. R., Gloyn, A. L., Strauch, K., Tuomi, T., Kooner, J. S., Lee, J. Y., Park, T., Donnelly, P., Morris, A. D., Hattersley, A. T., Bowden, D. W., Collins, F. S., Atzmon, G., Chambers, J. C., Spector, T. D., Laakso, M., Strom, T. M., Bell, G. I., Blangero, J., Duggirala, R., Tai, E. S., McVean, G., Hanis, C. L., Wilson, J. G., Seielstad, M., Frayling, T. M., Meigs, J. B., Cox, N. J., Sladek, R., Lander, E. S., Gabriel, S., Mohlke, K. L., Meitinger, T., Groop, L., Abecasis, G., Scott, L. J., Morris, A. P., Kang, H. M., Altshuler, D., Burtt, N. P., Florez, J. C., Boehnke, M. & McCarthy, M. I., Jan 23 2018, In: Scientific Data. 5, p. 180002 1 p.

    Research output: Contribution to journal › Comment/debate › peer-review

  • Mouse Metanephric Mesenchymal Cell–Derived Angioblasts Undergo Vasculogenesis in Three-Dimensional Culture

    Patel, M., Velagapudi, C., Burns, H., Doss, R., Lee, M. J., Mariappan, M. M., Wagner, B., Arar, M., Barnes, V. L., Abboud, H. E. & Barnes, J. L., Mar 2018, In: American Journal of Pathology. 188, 3, p. 768-784 17 p.

    Research output: Contribution to journal › Article › peer-review

  • Nox4 is a Target for Tuberin Deficiency Syndrome

    Shi, Q., Viswanadhapalli, S., Friedrichs, W. E., Velagapudi, C., Szyndralewiez, C., Bansal, S., Bhat, M. A., Choudhury, G. G. & Abboud, H. E., Dec 1 2018, In: Scientific reports. 8, 1, 3781.

    Research output: Contribution to journal › Article › peer-review

    2 Scopus citations
  • 2017

    A Loss-of-Function Splice Acceptor Variant in IGF2 Is Protective for Type 2 Diabetes

    Broad Genomics Platform, T2D-GENES Consortium, SIGMA T2D Genetics Consortium & Diabetes Prevention Program Research Group, Nov 1 2017, In: Diabetes. 66, 11, p. 2903-2914 12 p.

    Research output: Contribution to journal › Article › peer-review

    18 Scopus citations

  • A low-frequency inactivating AKT2 variant enriched in the finnish population is associated with fasting insulin levels and type 2 diabetes risk

    Manning, A., Highland, H. M., Gasser, J., Sim, X., Tukiainen, T., Fontanillas, P., Grarup, N., Rivas, M. A., Mahajan, A., Locke, A. E., Cingolani, P., Pers, T. H., Viñuela, A., Brown, A. A., Wu, Y., Flannick, J., Fuchsberger, C., Gamazon, E. R., Gaulton, K. J., Im, H. K. & 243 others, Teslovich, T. M., Blackwell, T. W., Bork-Jensen, J., Burtt, N. P., Chen, Y., Green, T., Hartl, C., Kang, H. M., Kumar, A., Ladenvall, C., Ma, C., Moutsianas, L., Pearson, R. D., Perry, J. R. B., Rayner, N. W., Robertson, N. R., Scott, L. J., van de Bunt, M., Eriksson, J. G., Jula, A., Koskinen, S., Lehtimäki, T., Palotie, A., Raitakari, O. T., Jacobs, S. B. R., Wessel, J., Chu, A. Y., Scott, R. A., Goodarzi, M. O., Blancher, C., Buck, G., Buck, D., Chines, P. S., Gabriel, S., Gjesing, A. P., Groves, C. J., Hollensted, M., Huyghe, J. R., Jackson, A. U., Jun, G., Justesen, J. M., Mangino, M., Murphy, J., Neville, M., Onofrio, R., Small, K. S., Stringham, H. M., Trakalo, J., Banks, E., Carey, J., Carneiro, M. O., Depristo, M., Farjoun, Y., Fennell, T., Goldstein, J. I., Grant, G., de Angelis, M. H., Maguire, J., Neale, B. M., Poplin, R., Purcell, S., Schwarzmayr, T., Shakir, K., Smith, J. D., Strom, T. M., Wieland, T., Lindstrom, J., Brandslund, I., Christensen, C., Surdulescu, G. L., Lakka, T. A., Doney, A. S. F., Nilsson, P., Wareham, N. J., Langenberg, C., Varga, T. V., Franks, P. W., Rolandsson, O., Rosengren, A. H., Farook, V. S., Thameem, F., Puppala, S., Kumar, S., Lehman, D. M., Jenkinson, C. P., Curran, J. E., Hale, D. E., Fowler, S. P., Arya, R., Defronzo, R. A., Abboud, H. E., Syvänen, A. C., Hicks, P. J., Palmer, N. D., Ng, M. C. Y., Bowden, D. W., Freedman, B. I., Esko, T., Mägi, R., Milani, L., Mihailov, E., Metspalu, A., Narisu, N., Kinnunen, L., Bonnycastle, L. L., Swift, A., Pasko, D., Wood, A. R., Fadista, J., Pollin, T. I., Barzilai, N., Atzmon, G., Glaser, B., Thorand, B., Strauch, K., Peters, A., Roden, M., Müller-Nurasyid, M., Liang, L., Kriebel, J., Illig, T., Grallert, H., Gieger, C., Meisinger, C., Lannfelt, L., Musani, S. K., Griswold, M., Taylor, H. A., Wilson, G., Correa, A., Oksa, H., Scott, W. R., Afzal, U., Tan, S. T., Loh, M., Chambers, J. C., Sehmi, J., Kooner, J. S., Lehne, B., Cho, Y. S., Lee, J. Y., Han, B. G., Käräjämäki, A., Qi, Q., Qi, L., Huang, J., Hu, F. B., E Mel Ander, O. L., Orho-Melander, M., Below, J. E., Aguilar, D., Wong, T. Y., U, J. L., Khor, C. C., Chia, K. S., Lim, W. Y., Cheng, C. Y., Chan, E., Shyong Tai, E., Aung, T., Linneberg, A., Isomaa, B., Meitinger, T., Tuomi, T., Hakaste, L., Na Kravi C, J., Jørgensen, M. E., Lauritzen, T., Deloukas, P., Stirrups, K. E., Kat, K. H., Farmer, A. J., Frayling, T. M., O’rahilly, S. P., Walker, M., Levy, J. C., Hodgkiss, D., Hattersley, A. T., Kuulasmaa, T., Stan?cáková, A., Barroso, I., Bharadwaj, D., Chan, J., Chandak, G. R., Daly, M. J., Donnelly, P. J., Ebrahim, S. B., Elliott, P., Fingerlin, T., Froguel, P., Hu, C., Jia, W., Ma, R. C. W., McVean, G., Park, T., Prabhakaran, D., Sandhu, M., Scott, J., Sladek, R., Tandon, N., Teo, Y. Y., Zeggini, E., Watanabe, R. M., Koistinen, H. A., Antero Kesaniemi, Y., Uusitupa, M., Spector, T. D., Salomaa, V., Rauramaa, R., Palmer, C. N. A., Prokopenko, I., Morris, A. D., Bergman, R. N., Collins, F. S., Lind, L., Ingelsson, E., Tuomilehto, J., Karpe, F., Groop, L., Jørgensen, T., Hansen, T., Pedersen, O., Kuusisto, J., Abecasis, G., Bell, G. I., Blangero, J., Cox, N. J., Duggirala, R., Seielstad, M., Wilson, J. G., Dupuis, J., Ripatti, S., Hanis, C. L., Florez, J. C., Mohlke, K. L., Meigs, J. B., Laakso, M., Morris, A. P., Boehnke, M., Altshuler, D., McCarthy, M. I., Gloyn, A. L. & Lindgren, C. M., Jul 1 2017, In: Diabetes. 66, 7, p. 2019-2032 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    23 Scopus citations

  • Data Descriptor: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

    Flannick, J., Fuchsberger, C., Mahajan, A., Teslovich, T. M., Agarwala, V., Gaulton, K. J., Caulkins, L., Koesterer, R., Ma, C., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Tajes, J. F. & 281 others, Highland, H. M., Dupuis, J., Chines, P. S., Lindgren, C. M., Hartl, C., Jackson, A. U., Chen, H., Huyghe, J. R., Van De Bunt, M., Pearson, R. D., Kumar, A., Müller-Nurasyid, M., Grarup, N., Stringham, H. M., Gamazon, E. R., Lee, J., Chen, Y., Scott, R. A., Below, J. E., Chen, P., Huang, J., Go, M. J., Stitzel, M. L., Pasko, D., Parker, S. C. J., Varga, T. V., Green, T., Beer, N. L., Day-Williams, A. G., Ferreira, T., Fingerlin, T., Horikoshi, M., Hu, C., Huh, I., Ikram, M. K., Kim, B. J., Kim, Y., Kim, Y. J., Kwon, M. S., Lee, J., Lee, S., Lin, K. H., Maxwell, T. J., Nagai, Y., Wang, X., Welch, R. P., Yoon, J., Zhang, W., Barzilai, N., Voight, B. F., Han, B. G., Jenkinson, C. P., Kuulasmaa, T., Kuusisto, J., Manning, A., Ng, M. C. Y., Palmer, N. D., Balkau, B., Stančáková, A., Abboud, H. E., Boeing, H., Giedraitis, V., Prabhakaran, D., Gottesman, O., Scott, J., Carey, J., Kwan, P., Grant, G., Smith, J. D., Neale, B. M., Purcell, S., Butterworth, A. S., Howson, J. M. M., Lee, H. M., Lu, Y., Kwak, S. H., Zhao, W., Danesh, J., Lam, V. K. L., Park, K. S., Saleheen, D., So, W. Y., Tam, C. H. T., Afzal, U., Aguilar, D., Arya, R., Aung, T., Chan, E., Navarro, C., Cheng, C. Y., Palli, D., Correa, A., Curran, J. E., Rybin, D., Farook, V. S., Fowler, S. P., Freedman, B. I., Griswold, M., Hale, D. E., Hicks, P. J., Khor, C. C., Kumar, S., Lehne, B., Thuillier, D., Lim, W. Y., Liu, J., Loh, M., Musani, S. K., Puppala, S., Scott, W. R., Yengo, L., Tan, S. T., Taylor, H. A., Thameem, F., Wilson, G., Wong, T. Y., Njølstad, P. R., Levy, J. C., Mangino, M., Bonnycastle, L. L., Schwarzmayr, T., Fadista, J., Surdulescu, G. L., Herder, C., Groves, C. J., Wieland, T., Bork-Jensen, J., Brandslund, I., Christensen, C., Koistinen, H. A., Doney, A. S. F., Kinnunen, L., Esko, T., Farmer, A. J., Hakaste, L., Hodgkiss, D., Kravic, J., Lyssenko, V., Hollensted, M., Jørgensen, M. E., Jørgensen, T., Ladenvall, C., Justesen, J. M., Käräjämäki, A., Kriebel, J., Rathmann, W., Lannfelt, L., Lauritzen, T., Narisu, N., Linneberg, A., Melander, O., Milani, L., Neville, M., Orho-Melander, M., Qi, L., Qi, Q., Roden, M., Rolandsson, O., Swift, A., Rosengren, A. H., Stirrups, K., Wood, A. R., Mihailov, E., Blancher, C., Carneiro, M. O., Maguire, J., Poplin, R., Shakir, K., Fennell, T., DePristo, M., De Angelis, M. H., Deloukas, P., Gjesing, A. P., Jun, G., Nilsson, P. M., Murphy, J., Onofrio, R., Thorand, B., Hansen, T., Meisinger, C., Hu, F. B., Isomaa, B., Karpe, F., Liang, L., Peters, A., Huth, C., O'Rahilly, S. P., Palmer, C. N. A., Pedersen, O., Rauramaa, R., Tuomilehto, J., Salomaa, V., Watanabe, R. M., Syvänen, A. C., Bergman, R. N., Bharadwaj, D., Bottinger, E. P., Cho, Y. S., Chandak, G. R., Chan, J. C. N., Chia, K. S., Daly, M. J., Ebrahim, S. B., Langenberg, C., Elliott, P., Jablonski, K. A., Lehman, D. M., Jia, W., Ma, R. C. W., Pollin, T. I., Sandhu, M., Tandon, N., Froguel, P., Barroso, I., Teo, Y. Y., Zeggini, E., Loos, R. J. F., Small, K. S., Ried, J. S., DeFronzo, R. A., Grallert, H., Glaser, B., Metspalu, A., Wareham, N. J., Walker, M., Banks, E., Gieger, C., Ingelsson, E., Im, H. K., Illig, T., Franks, P. W., Buck, G., Trakalo, J., Buck, D., Prokopenko, I., Mägi, R., Lind, L., Farjoun, Y., Owen, K. R., Gloyn, A. L., Strauch, K., Tuomi, T., Kooner, J. S., Lee, J. Y., Park, T., Donnelly, P., Morris, A. D., Hattersley, A. T., Bowden, D. W., Collins, F. S., Atzmon, G., Chambers, J. C., Spector, T. D., Laakso, M., Strom, T. M., Bell, G. I., Blangero, J., Duggirala, R., Tai, E., McVean, G., Hanis, C. L., Wilson, J. G., Seielstad, M., Frayling, T. M., Meigs, J. B., Cox, N. J., Sladek, R., Lander, E. S., Gabriel, S., Mohlke, K. L., Meitinger, T., Groop, L., Abecasis, G., Scott, L. J., Morris, A. P., Kang, H. M., Altshuler, D., Burtt, N. P., Florez, J. C., Boehnke, M. & McCarthy, M. I., Dec 19 2017, In: Scientific Data. 4, 170179.

    Research output: Contribution to journal › Article › peer-review

    10 Scopus citations

  • Hydrogen sulfide inhibits high glucose-induced NADPH oxidase 4 expression and matrix increase by recruiting inducible nitric oxide synthase in kidney proximal tubular epithelial cells

    Lee, H. J., Lee, D. Y., Mariappan, M. M., Feliers, D., Ghosh-Choudhury, G., Abboud, H. E., Gorin, Y. & Kasinath, B. S., Apr 7 2017, In: Journal of Biological Chemistry. 292, 14, p. 5665-5675 11 p.

    Research output: Contribution to journal › Article › peer-review

    21 Scopus citations

  • Tryptophan metabolism in patients with chronic kidney disease secondary to type 2 diabetes: Relationship to inflammatory markers

    Debnath, S., Velagapudi, C., Redus, L., Thameem, F., Kasinath, B., Hura, C. E., Lorenzo, C., Abboud, H. E. & O'Connor, J. C., 2017, In: International Journal of Tryptophan Research. 10, 1

    Research output: Contribution to journal › Article › peer-review

    34 Scopus citations
  • 2016

    Analysis of protein-coding genetic variation in 60,706 humans

    Lek, M., Karczewski, K. J., Minikel, E. V., Samocha, K. E., Banks, E., Fennell, T., O'Donnell-Luria, A. H., Ware, J. S., Hill, A. J., Cummings, B. B., Tukiainen, T., Birnbaum, D. P., Kosmicki, J. A., Duncan, L. E., Estrada, K., Zhao, F., Zou, J., Pierce-Hoffman, E., Berghout, J., Cooper, D. N. & 153 others, Deflaux, N., DePristo, M., Do, R., Flannick, J., Fromer, M., Gauthier, L., Goldstein, J., Gupta, N., Howrigan, D., Kiezun, A., Kurki, M. I., Moonshine, A. L., Natarajan, P., Orozco, L., Peloso, G. M., Poplin, R., Rivas, M. A., Ruano-Rubio, V., Rose, S. A., Ruderfer, D. M., Shakir, K., Stenson, P. D., Stevens, C., Thomas, B. P., Tiao, G., Tusie-Luna, M. T., Weisburd, B., Won, H. H., Yu, D., Altshuler, D. M., Ardissino, D., Boehnke, M., Danesh, J., Donnelly, S., Elosua, R., Florez, J. C., Gabriel, S. B., Getz, G., Glatt, S. J., Hultman, C. M., Kathiresan, S., Laakso, M., McCarroll, S., McCarthy, M. I., McGovern, D., McPherson, R., Neale, B. M., Palotie, A., Purcell, S. M., Saleheen, D., Scharf, J. M., Sklar, P., Sullivan, P. F., Tuomilehto, J., Tsuang, M. T., Watkins, H. C., Wilson, J. G., Daly, M. J., MacArthur, D. G., Abboud, H. E., Abecasis, G., Aguilar-Salinas, C. A., Arellano-Campos, O., Atzmon, G., Aukrust, I., Barr, C. L., Bell, G. I., Bergen, S., Bjørkhaug, L., Blangero, J., Bowden, D. W., Budman, C. L., Burtt, N. P., Centeno-Cruz, F., Chambers, J. C., Chambert, K., Clarke, R., Collins, R., Coppola, G., Córdova, E. J., Cortes, M. L., Cox, N. J., Duggirala, R., Farrall, M., Fernandez-Lopez, J. C., Fontanillas, P., Frayling, T. M., Freimer, N. B., Fuchsberger, C., García-Ortiz, H., Goel, A., Gómez-Vázquez, M. J., González-Villalpando, M. E., González-Villalpando, C., Grados, M. A., Groop, L., Haiman, C. A., Hanis, C. L., Hattersley, A. T., Henderson, B. E., Hopewell, J. C., Huerta-Chagoya, A., Islas-Andrade, S., Jacobs, S. B., Jalilzadeh, S., Jenkinson, C. P., Moran, J., Jiménez-Morale, S., Kähler, A., King, R. A., Kirov, G., Kooner, J. S., Kyriakou, T., Lee, J. Y., Lehman, D. M., Lyon, G., MacMahon, W., Magnusson, P. K., Mahajan, A., Marrugat, J., Martínez-Hernández, A., Mathews, C. A., McVean, G., Meigs, J. B., Meitinger, T., Mendoza-Caamal, E., Mercader, J. M., Mohlke, K. L., Moreno-Macías, H., Morris, A. P., Najmi, L. A., Njølstad, P. R., O'Donovan, M. C., Ordóñez-Sánchez, M. L., Owen, M. J., Park, T., Pauls, D. L., Posthuma, D., Revilla-Monsalve, C., Riba, L., Ripke, S., Rodríguez-Guillén, R., Rodríguez-Torres, M., Sandor, P., Seielstad, M., Sladek, R., Soberón, X., Spector, T. D., Tai, S. E., Teslovich, T. M., Walford, G., Wilkens, L. R. & Williams, A. L., Aug 17 2016, In: Nature. 536, 7616, p. 285-291 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    5144 Scopus citations

  • Genetic variants in toll-like receptor 4 gene and their association analysis with estimated glomerular filtration rate in Mexican American families

    Thameem, F., Puppala, S., Farook, V. S., Kasinath, B. S., Blangero, J., Duggirala, R. & Abboud, H. E., Aug 1 2016, In: CardioRenal Medicine. 6, 4, p. 301-306 6 p.

    Research output: Contribution to journal › Article › peer-review

    2 Scopus citations

  • MTORC2 Signaling Regulates Nox4-Induced Podocyte Depletion in Diabetes

    Eid, S., Boutary, S., Braych, K., Sabra, R., Massaad, C., Hamdy, A., Rashid, A., Moodad, S., Block, K., Gorin, Y., Abboud, H. E. & Eid, A. A., Nov 1 2016, In: Antioxidants and Redox Signaling. 25, 13, p. 703-719 17 p.

    Research output: Contribution to journal › Article › peer-review

    33 Scopus citations

  • Selecting SNPs informative for African, American Indian and European Ancestry: Application to the Family Investigation of Nephropathy and Diabetes (FIND)

    Williams, R. C., Elston, R. C., Kumar, P., Knowler, W. C., Abboud, H. E., Adler, S., Bowden, D. W., Divers, J., Freedman, B. I., Igo, R. P., Ipp, E., Iyengar, S. K., Kimmel, P. L., Klag, M. J., Kohn, O., Langefeld, C. D., Leehey, D. J., Nelson, R. G., Nicholas, S. B., Pahl, M. V. & 108 others, Parekh, R. S., Rotter, J. I., Schelling, J. R., Sedor, J. R., Shah, V. O., Smith, M. W., Taylor, K. D., Thameem, F., Thornley-Brown, D., Winkler, C. A., Guo, X., Zager, P., Hanson, R. L., FIND Research Group, R. G., S.K. Iyengar, I., Elston, R. C., Goddard, K. A. B., Olson, J. M., Ialacci, S., Fondran, J., Horvath, A., Igo, R., Jun, G., Kramp, K., Molineros, J., Quade, S. R. E., Schelling, J., Pickens, A., Humbert, L., Getz-Fradley, L., Adler, S., Ipp, E., Pahl, M., Seldin, M. F., Snyder, S., Tayek, J., Hernandez, E., LaPage, J., Garcia, C., Gonzalez, J., Aguilar, M., Parekh, R., Kao, L., Meoni, L., Whitehead, T., Chester, J., Knowler, W. C., Hanson, R. L., Nelson, R. G., Wolford, J., Jones, L., Juan, R., Lovelace, R., Luethe, C., Phillips, L. M., Sewemaenewa, J., Sili, I., Waseta, B., Saad, M. F., Nicholas, S. B., Chen, Y. D. I., Guo, X., Rotter, J., Taylor, K., Budgett, M., Hariri, F., Zager, P., Shah, V., Scavini, M., Bobelu, A., Abboud, H., Arar, N., Duggirala, R., Kasinath, B. S., Thameem, F., Stern, M., Freedman, B. I., Bowden, D. W., Langefeld, C. D., Satko, S. C., Rich, S. S., Warren, S., Viverette, S., Brooks, G., Young, R., Spainhour, M., Winkler, C., Smith, M. W., Thompson, M., Hanson, R., Kessing, B., Leehey, D. J., Barone, G., Thornley-Brown, D., Jefferson, C., Kohn, O. F., Brown, C. S., Briggs, J. P., Kimmel, P. L., Rasooly, R., D. Warnock, W., Cardon, L., Chakraborty, R., Dunston, G. M., Hostetter, T., O'Brien, S. J., Rioux, J. & Spielman, R., May 4 2016, In: BMC genomics. 17, 1, 325.

    Research output: Contribution to journal › Article › peer-review

    1 Scopus citations

  • The genetic architecture of type 2 diabetes

    Fuchsberger, C., Flannick, J., Teslovich, T. M., Mahajan, A., Agarwala, V., Gaulton, K. J., Ma, C., Fontanillas, P., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Tajes, J. F., Highland, H. M. & 281 others, Dupuis, J., Chines, P. S., Lindgren, C. M., Hartl, C., Jackson, A. U., Chen, H., Huyghe, J. R., Van De Bunt, M., Pearson, R. D., Kumar, A., Müller-Nurasyid, M., Grarup, N., Stringham, H. M., Gamazon, E. R., Lee, J., Chen, Y., Scott, R. A., Below, J. E., Chen, P., Huang, J., Go, M. J., Stitzel, M. L., Pasko, D., Parker, S. C. J., Varga, T. V., Green, T., Beer, N. L., Day-Williams, A. G., Ferreira, T., Fingerlin, T., Horikoshi, M., Hu, C., Huh, I., Ikram, M. K., Kim, B. J., Kim, Y., Kim, Y. J., Kwon, M. S., Lee, J., Lee, S., Lin, K. H., Maxwell, T. J., Nagai, Y., Wang, X., Welch, R. P., Yoon, J., Zhang, W., Barzilai, N., Voight, B. F., Han, B. G., Jenkinson, C. P., Kuulasmaa, T., Kuusisto, J., Manning, A., Ng, M. C. Y., Palmer, N. D., Balkau, B., Stančáková, A., Abboud, H. E., Boeing, H., Giedraitis, V., Prabhakaran, D., Gottesman, O., Scott, J., Carey, J., Kwan, P., Grant, G., Smith, J. D., Neale, B. M., Purcell, S., Butterworth, A. S., Howson, J. M. M., Lee, H. M., Lu, Y., Kwak, S. H., Zhao, W., Danesh, J., Lam, V. K. L., Park, K. S., Saleheen, D., So, W. Y., Tam, C. H. T., Afzal, U., Aguilar, D., Arya, R., Aung, T., Chan, E., Navarro, C., Cheng, C. Y., Palli, D., Correa, A., Curran, J. E., Rybin, D., Farook, V. S., Fowler, S. P., Freedman, B. I., Griswold, M., Hale, D. E., Hicks, P. J., Khor, C. C., Kumar, S., Lehne, B., Thuillier, D., Lim, W. Y., Liu, J., Van Der Schouw, Y. T., Loh, M., Musani, S. K., Puppala, S., Scott, W. R., Yengo, L., Tan, S. T., Taylor, H. A., Thameem, F., Wilson, G., Wong, T. Y., Njolstad, P. R., Levy, J. C., Mangino, M., Bonnycastle, L. L., Schwarzmayr, T., Fadista, J., Surdulescu, G. L., Herder, C., Groves, C. J., Wieland, T., Bork-Jensen, J., Brandslund, I., Christensen, C., Koistinen, H. A., Doney, A. S. F., Kinnunen, L., Esko, T., Farmer, A. J., Hakaste, L., Hodgkiss, D., Kravic, J., Lyssenko, V., Hollensted, M., Jorgensen, M. E., Jorgensen, T., Ladenvall, C., Justesen, J. M., Käräjämäki, A., Kriebel, J., Rathmann, W., Lannfelt, L., Lauritzen, T., Narisu, N., Linneberg, A., Melander, O., Milani, L., Neville, M., Orho-Melander, M., Qi, L., Qi, Q., Roden, M., Rolandsson, O., Swift, A., Rosengren, A. H., Stirrups, K., Wood, A. R., Mihailov, E., Blancher, C., Carneiro, M. O., Maguire, J., Poplin, R., Shakir, K., Fennell, T., DePristo, M., De Angelis, M. H., Deloukas, P., Gjesing, A. P., Jun, G., Nilsson, P., Murphy, J., Onofrio, R., Thorand, B., Hansen, T., Meisinger, C., Hu, F. B., Isomaa, B., Karpe, F., Liang, L., Peters, A., Huth, C., O'Rahilly, S. P., Palmer, C. N. A., Pedersen, O., Rauramaa, R., Tuomilehto, J., Salomaa, V., Watanabe, R. M., Syvänen, A. C., Bergman, R. N., Bharadwaj, D., Bottinger, E. P., Cho, Y. S., Chandak, G. R., Chan, J. C. N., Chia, K. S., Daly, M. J., Ebrahim, S. B., Langenberg, C., Elliott, P., Jablonski, K. A., Lehman, D. M., Jia, W., Ma, R. C. W., Pollin, T. I., Sandhu, M., Tandon, N., Froguel, P., Barroso, I., Teo, Y. Y., Zeggini, E., Loos, R. J. F., Small, K. S., Ried, J. S., DeFronzo, R. A., Grallert, H., Glaser, B., Metspalu, A., Wareham, N. J., Walker, M., Banks, E., Gieger, C., Ingelsson, E., Im, H. K., Illig, T., Franks, P. W., Buck, G., Trakalo, J., Buck, D., Prokopenko, I., Mägi, R., Lind, L., Farjoun, Y., Owen, K. R., Gloyn, A. L., Strauch, K., Tuomi, T., Kooner, J. S., Lee, J. Y., Park, T., Donnelly, P., Morris, A. D., Hattersley, A. T., Bowden, D. W., Collins, F. S., Atzmon, G., Chambers, J. C., Spector, T. D., Laakso, M., Strom, T. M., Bell, G. I., Blangero, J., Duggirala, R., Tai, E. S., McVean, G., Hanis, C. L., Wilson, J. G., Seielstad, M., Frayling, T. M., Meigs, J. B., Cox, N. J., Sladek, R., Lander, E. S., Gabriel, S., Burtt, N. P., Mohlke, K. L., Meitinger, T., Groop, L., Abecasis, G., Florez, J. C., Scott, L. J., Morris, A. P., Kang, H. M., Boehnke, M., Altshuler, D. & McCarthy, M. I., Jul 11 2016, In: Nature. 536, 7614, p. 41-47 7 p.

    Research output: Contribution to journal › Article › peer-review

    524 Scopus citations

  • Tuberin regulates reactive oxygen species in renal proximal cells, kidney from rodents, and kidney from patients with tuberous sclerosis complex

    Habib, S. L. & Abboud, H. E., Aug 1 2016, In: Cancer Science. 107, 8, p. 1092-1100 9 p.

    Research output: Contribution to journal › Article › peer-review

    5 Scopus citations
  • 2015

    Activation of AMP-Activated Protein Kinase Prevents TGF-β1-Induced Epithelial-Mesenchymal Transition and Myofibroblast Activation

    Thakur, S., Viswanadhapalli, S., Kopp, J. B., Shi, Q., Barnes, J. L., Block, K., Gorin, Y. & Abboud, H. E., Aug 1 2015, In: American Journal of Pathology. 185, 8, p. 2168-2180 13 p.

    Research output: Contribution to journal › Article › peer-review

    45 Scopus citations

  • Diabetic cardiomyopathy; Summary of 41 years

    Yilmaz, S., Canpolat, U., Aydogdu, S. & Abboud, H. E., Jul 1 2015, In: Korean Circulation Journal. 45, 4, p. 266-272 7 p.

    Research output: Contribution to journal › Review article › peer-review

    39 Scopus citations

  • Evaluation of Neurotrophic Tyrosine Receptor Kinase 2 (NTRK2) as a positional candidate gene for variation in estimated Glomerular Filtration Rate (eGFR) in Mexican American participants of San Antonio Family Heart Study

    Thameem, F., Voruganti, V. S., Blangero, J., Comuzzie, A. G. & Abboud, H. E., 2015, In: Journal of Biomedical Science. 22, 1, 23.

    Research output: Contribution to journal › Article › peer-review

    2 Scopus citations

  • Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND)

    Iyengar, S. K., Sedor, J. R., Freedman, B. I., Kao, W. H. L., Kretzler, M., Keller, B. J., Abboud, H. E., Adler, S. G., Best, L. G., Bowden, D. W., Burlock, A., Chen, Y. D. I., Cole, S. A., Comeau, M. E., Curtis, J. M., Divers, J., Drechsler, C., Duggirala, R., Elston, R. C., Guo, X. & 39 others, Huang, H., Hoffmann, M. M., Howard, B. V., Ipp, E., Kimmel, P. L., Klag, M. J., Knowler, W. C., Kohn, O. F., Leak, T. S., Leehey, D. J., Li, M., Malhotra, A., März, W., Nair, V., Nelson, R. G., Nicholas, S. B., O’Brien, S. J., Pahl, M. V., Parekh, R. S., Pezzolesi, M. G., Rasooly, R. S., Rotimi, C. N., Rotter, J. I., Schelling, J. R., Seldin, M. F., Shah, V. O., Smiles, A. M., Smith, M. W., Taylor, K. D., Thameem, F., Thornley-Brown, D. P., Truitt, B. J., Wanner, C., Weil, E. J., Winkler, C. A., Zager, P. G., Igo, R. P., Hanson, R. L. & Langefeld, C. D., Aug 1 2015, In: PLoS Genetics. 11, 8, e1005352.

    Research output: Contribution to journal › Article › peer-review

    62 Scopus citations

  • Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus

    Mahajan, A., Sim, X., Ng, H. J., Manning, A., Rivas, M. A., Highland, H. M., Locke, A. E., Grarup, N., Im, H. K., Cingolani, P., Flannick, J., Fontanillas, P., Fuchsberger, C., Gaulton, K. J., Teslovich, T. M., Rayner, N. W., Robertson, N. R., Beer, N. L., Rundle, J. K., Bork-Jensen, J. & 243 others, Ladenvall, C., Blancher, C., Buck, D., Buck, G., Burtt, N. P., Gabriel, S., Gjesing, A. P., Groves, C. J., Hollensted, M., Huyghe, J. R., Jackson, A. U., Jun, G., Justesen, J. M., Mangino, M., Murphy, J., Neville, M., Onofrio, R., Small, K. S., Stringham, H. M., Syvänen, A. C., Trakalo, J., Abecasis, G., Bell, G. I., Blangero, J., Cox, N. J., Duggirala, R., Hanis, C. L., Seielstad, M., Wilson, J. G., Christensen, C., Brandslund, I., Rauramaa, R., Surdulescu, G. L., Doney, A. S. F., Lannfelt, L., Linneberg, A., Isomaa, B., Tuomi, T., Jørgensen, M. E., Jørgensen, T., Kuusisto, J., Uusitupa, M., Salomaa, V., Spector, T. D., Morris, A. D., Palmer, C. N. A., Collins, F. S., Mohlke, K. L., Bergman, R. N., Ingelsson, E., Lind, L., Tuomilehto, J., Hansen, T., Watanabe, R. M., Prokopenko, I., Dupuis, J., Karpe, F., Groop, L., Laakso, M., Pedersen, O., Florez, J. C., Morris, A. P., Altshuler, D., Meigs, J. B., Boehnke, M., McCarthy, M. I., Lindgren, C. M., Gloyn, A. L., Abboud, H. E., Afzal, U., Aguilar, D., Arya, R., Atzmon, G., Aung, T., Banks, E., Barroso, I., Barzilai, N., Below, J. E., Bharadwaj, D., Blackwell, T. W., Bonnycastle, L. L., Bowden, D., Carey, J., Carneiro, M. O., Chambers, J. C., Chan, E., Chan, J., Chandak, G. R., Chen, P., Chen, Y., Chen, H., Cheng, C. Y., Chia, K. S., Cho, Y. S., Correa, A., Curran, J. E., Daly, M. J., Day-Williams, A. G., DeFronzo, R. A., DePristo, M., Donnelly, P. J., Ebrahim, S. B., Elliott, P., Esko, T., Fadista, J., Farjoun, Y., Farmer, A. J., Farook, V. S., Fennell, T., Ferreira, T., Fingerlin, T., Forsén, T., Fowler, S. P., Franks, P. W., Frayling, T. M., Freedman, B. I., Froguel, P., Gamazon, E. R., Gieger, C., Glaser, B., Go, M. J., Goldstein, J. I., Grallert, H., Grant, G., Green, T., Griswold, M., Hale, D. E., Han, B. G., Hartl, C., Hattersley, A. T., Hicks, P. J., Hodgkiss, D., Horikoshi, M., Hrabé de Angelis, M., Hu, C., Hu, F. B., Huh, I., Kamran Ikram, M., Illig, T., Jablonski, K. A., Jenkinson, C. P., Jia, W., Kang, H. M., Khor, C. C., Kim, Y., Kim, Y. J., Kim, B. J., Kinnunen, L., Kooner, J. S., Kravic, J., Kriebel, J., Kumar, A., Kumar, S., Kuulasmaa, T., Kwon, M. S., Langenberg, C., Lauritzen, T., Lee, S., Lee, J., Lee, J., Lee, J. Y., Lehman, D. M., Lehne, B., Levy, J. C., Li, J., Liang, L., Lim, W. Y., Lin, K. H., Liu, J., Loh, M., Ma, R. C. W., Ma, C., Mägi, R., Maguire, J., Maxwell, T. J., McVean, G., Meisinger, C., Meitinger, T., Melander, O., Metspalu, A., Mihailov, E., Milani, L., Moutsianas, L., Müller-Nurasyid, M., K. Musani, S., Nagai, Y., Narisu, N., Neale, B. M., Ng, M. C. Y., Nilsson, P., O'Rahilly, S. P., Orho-Melander, M., Owen, K. R., Palmer, N. D., Park, T., Pasko, D., Pearson, R. D., Perry, J. R. B., Peters, A., Pollin, T. I., Poplin, R., Prabhakaran, D., Puppala, S., Purcell, S., Qi, L., Qi, Q., Roden, M., Rolandsson, O., Rosengren, A. H., Sandhu, M., Schwarzmayr, T., Scott, L. J., Scott, R. A., Scott, J., Scott, W. R., Sehmi, J., Shakir, K., Sladek, R., Smith, J. D., Stancáková, A., Strauch, K., Strom, T. M., Swift, A., Tai, E. S., Tajes, J. F., Tan, S. T., Tandon, N., Taylor, H. A., Teo, Y. Y., Thameem, F., Thorand, B., van de Bunt, M., Varga, T. V., Walker, M., Wareham, N. J., Welch, R. P., Wieland, T., Wilson, G., Wong, T. Y., Wood, A. R., Yoon, J., Zeggini, E. & Zhang, W., Jan 27 2015, In: PLoS Genetics. 11, 1, e1004876.

    Research output: Contribution to journal › Article › peer-review

    61 Scopus citations

  • Layer-specific manganese-enhanced MRI of the diabetic rat retina in light and dark adaptation at 11.7 tesla

    Muir, E. R., Chandra, S. B., De La Garza, B. H., Velagapudi, C., Abboud, H. E. & Duong, T. Q., 2015, In: Investigative Ophthalmology and Visual Science. 56, 6, p. 4006-4012 7 p.

    Research output: Contribution to journal › Article › peer-review

    6 Scopus citations

  • Membranous nephropathy and cerebellar degeneration with anti-GAD antibodies in type 2 diabetes mellitus

    Folli, F., Daniele, G., Werner, S., Kamath, S., Munera, J. V., Abboud, H. & Fanti, P., Mar 10 2015, (Accepted/In press) In: Acta Diabetologica.

    Research output: Contribution to journal › Article › peer-review

  • Metformin prevents renal interstitial fibrosis in mice with unilateral ureteral obstruction

    Cavaglieri, R. C., Day, R. T., Feliers, D. & Abboud, H. E., Sep 5 2015, In: Molecular and Cellular Endocrinology. 412, p. 116-122 7 p.

    Research output: Contribution to journal › Article › peer-review

    33 Scopus citations

  • NADPH oxidase 4 induces cardiac fibrosis and hypertrophy through activating Akt/mTOR and NFκB signaling pathways

    Zhao, Q. D., Viswanadhapalli, S., Williams, P., Shi, Q., Tan, C., Yi, X., Bhandari, B. & Abboud, H. E., 2015, In: Circulation. 131, 7, p. 643-655 13 p.

    Research output: Contribution to journal › Article › peer-review

    110 Scopus citations

  • Nox2 mediates skeletal muscle insulin resistance induced by a high fat diet

    De Figueiredo, A. S. P., Salmon, A. B., Bruno, F., Jimenez, F., Martinez, H. G., Halade, G. V., Ahuja, S. S., Clark, R. A., DeFronzo, R. A., Abboud, H. E. & El Jamali, A., May 22 2015, In: Journal of Biological Chemistry. 290, 21, p. 13427-13439 13 p.

    Research output: Contribution to journal › Article › peer-review

    46 Scopus citations

  • Targeting NADPH oxidase with a novel dual Nox1/Nox4 inhibitor attenuates renal pathology in type 1 diabetes

    Gorin, Y., Cavaglieri, R. C., Khazim, K., Lee, D. Y., Bruno, F., Thakur, S., Fanti, P., Szyndralewiez, C., Barnes, J. L., Block, K. & Abboud, H. E., Jun 1 2015, In: American Journal of Physiology - Renal Physiology. 308, 11, p. F1276-F1287

    Research output: Contribution to journal › Article › peer-review

    106 Scopus citations
  • 2014

    ADAM17 promotes proliferation of collecting duct kidney epithelial cells through ERK activation and increased glycolysis in polycystic kidney disease

    Gooz Beck, M., Maldonado, E. N., Dang, Y., Amria, M. Y., Higashiyama, S., Abboud, H. E., Lemasters, J. J. & Bell, P. D., Sep 1 2014, In: American Journal of Physiology - Renal Physiology. 307, 5, p. F551-F559

    Research output: Contribution to journal › Article › peer-review

    18 Scopus citations

  • A positive feedback loop involving Erk5 and Akt turns on mesangial cell proliferation in response to PDGF

    Bera, A., Das, F., Ghosh-Choudhury, N., Li, X., Pal, S., Gorin, Y., Kasinath, B. S., Abboud, H. E. & Ghosh Choudhury, G., Jun 1 2014, In: American Journal of Physiology - Cell Physiology. 306, 11, p. C1089-C1100

    Research output: Contribution to journal › Article › peer-review

    16 Scopus citations

  • Association of a low-frequency variant in HNF1A with type 2 diabetes in a latino population the SIGMA Type 2 Diabetes Consortium

    The SIGMA Type 2 Diabetes Consortium, 2014, In: JAMA - Journal of the American Medical Association. 311, 22, p. 2305-2314 10 p.

    Research output: Contribution to journal › Article › peer-review

    117 Scopus citations

  • Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes

    The MAGIC investigators & The GIANT consortium, Aug 7 2014, In: PLoS Genetics. 10, 8, e1004517.

    Research output: Contribution to journal › Article › peer-review

    119 Scopus citations

  • MicroRNA-21-induced dissociation of PDCD4 from rictor contributes to Akt-IKKβ-mTORC1 axis to regulate renal cancer cell invasion

    Bera, A., Das, F., Ghosh-Choudhury, N., Kasinath, B. S., Abboud, H. E. & Choudhury, G. G., Oct 15 2014, In: Experimental Cell Research. 328, 1, p. 99-117 19 p.

    Research output: Contribution to journal › Article › peer-review

    33 Scopus citations

  • Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico

    Williams Amy, A. L., Jacobs Suzanne, S. B. R., Moreno-Macías, H., Huerta-Chagoya, A., Churchhouse, C., Márquez-Luna, C., Gómez-Vázquez, M. J., Burtt Noël, N. P., Aguilar-Salinas, C. A., González-Villalpando, C., Florez, J. C., Orozco, L., Tusié-Luna, T., Altshuler, D., Ripke, S., Manning, A. K., García-Ortíz, H., Neale, B., Reich, D., Stram, D. O. & 93 others, Fernández-López, J. C., Romero-Hidalgo, S., Patterson, N., Haiman, C. A., Aguilar-Delfín, I., Martínez-Hernández, A., Centeno-Cruz, F., Mendoza-Caamal, E., Revilla-Monsalve, C., Islas-Andrade, S., Córdova, E., Rodríguez-Arellano, E., Soberón, X., Florez Jose, J. C., González-Villalpando María Elena, M. A., Henderson, B. E., Monroe, K., Wilkens, L., Kolonel, L. N., Le Marchand, L., Riba, L., Ordóñez-Sánchez María Luisa, M. A., Rodríguez-Guillén, R., Cruz-Bautista, I., Rodríguez-Torres, M., Muñoz-Hernández, L. L., Sáenz, T., Gómez, D., Alvirde, U., Onofrio, R. C., Brodeur, W. M., Gage, D., Murphy, J., Franklin, J., Mahan, S., Ardlie, K., Crenshaw, A. T., Winckler, W., Prüfer, K., Shunkov, M. V., Sawyer, S., Stenzel, U., Kelso, J., Lek, M., Sankararaman, S., MacArthur, D. G., Derevianko, A. P., Pääbo, S., Jacobs, S. B. R., Gopal, S., Grammatikos, J. A., Smith, I. C., Bullock, K. H., Deik, A. A., Souza, A. L., Pierce, K. A., Clish, C. B., Fennell, T., Farjoun, Y., Gabriel, S., Gross, M. D., Pereira, M. A., Seielstad, M., Koh, W. P., Tai, E. S., Flannick, J., Fontanillas, P., Morris, A., Teslovich, T. M., Atzmon, G., Blangero, J., Bowden, D. W., Chambers, J., Cho, Y. S., Duggirala, R., Glaser, B., Hanis, C., Kooner, J., Laakso, M., Lee, J. Y., Teo, Y. Y., Wilson, J. G., Puppala, S., Farook, V. S., Thameem, F., Abboud, H. E., DeFronzo, R. A., Jenkinson, C. P., Lehman, D. M., Curran, J. E., Cortes, M. L., González-Villalpando Clicerio, C. & Orozco Lorena, L., 2014, In: Nature. 506, 7486, p. 97-101 5 p.

    Research output: Contribution to journal › Article › peer-review

    269 Scopus citations

  • TGFβ-induced deptor suppression recruits mTORC1 and not mTORC2 to enhance collagen i (α2) gene expression

    Das, F., Bera, A., Ghosh-Choudhury, N., Abboud, H. E., Kasinath, B. S. & Choudhury, G. G., Oct 15 2014, In: PloS one. 9, 10, e109608.

    Research output: Contribution to journal › Article › peer-review

    26 Scopus citations
  • 2013

    ADAM17 mediates Nox4 expression and NADPH oxidase activity in the kidney cortex of OVE26 mice

    Ford, B. M., Eid, A. A., Göoz, M., Barnes, J. L., Gorin, Y. C. & Abboud, H. E., Aug 1 2013, In: American Journal of Physiology - Renal Physiology. 305, 3, p. F323-F332

    Research output: Contribution to journal › Article › peer-review

    23 Scopus citations

  • A genome-wide search for linkage of estimated glomerular filtration rate (eGFR) in the family investigation of nephropathy and diabetes (FIND)

    Thameem, F., Igo, R. P., Freedman, B. I., Langefeld, C., Hanson, R. L., Schelling, J. R., Elston, R. C., Duggirala, R., Nicholas, S. B., Goddard, K. A. B., Divers, J., Guo, X., Ipp, E., Kimmel, P. L., Meoni, L. A., Shah, V. O., Smith, M. W., Winkler, C. A., Zager, P. G., Knowler, W. C. & 9 others, Nelson, R. G., Pahl, M. V., Parekh, R. S., Kao, W. H. L., Rasooly, R. S., Adler, S. G., Abboud, H. E., Iyengar, S. K. & Sedor, J. R., Dec 17 2013, In: PloS one. 8, 12, e81888.

    Research output: Contribution to journal › Article › peer-review

    20 Scopus citations

  • Bardoxolone methyl in type 2 diabetes and stage 4 chronic kidney disease

    De Zeeuw, D., Akizawa, T., Audhya, P., Bakris, G. L., Chin, M., Christ-Schmidt, H., Goldsberry, A., Houser, M., Krauth, M., Lambers Heerspink, H. J., McMurray, J. J., Meyer, C. J., Parving, H. H., Remuzzi, G., Toto, R. D., Vaziri, N. D., Wanner, C., Wittes, J., Wrolstad, D., Chertow, G. M. & 334 others, Toto, B., McCullough, P., Ivanovich, P., Ketteler, M., Lachin, J., McGill, J., Agarwal, R., Anker, S., Arenillas, J. F., Januzzi, J., Jardine, A., Kasner, S., Kissela, B., Kolansky, D., Mann, J., Thadhani, R., Champion de Crespigny, P., Chan, D. T., D'Almeida, E., Fraser, I., Gray, N., Holt, S., Irish, A., Isbel, N., Kerr, P., Packham, D., Phoon, R., Pollock, C., Roger, S., Suranyi, M., Walker, R., Wittert, G., Yue, D., Balcke, P., Prager, R., Schernthaner, G., Schernthaner, G., Sunder-Plassmann, G., Jadoul, M., Krzesinski, J. M., Peeters, P., Van der Niepen, P., Van Gaal, L., Van Vlem, B., Warling, X., Chow, S., Cournoyer, S., Dumas, R., Jolly, S., Levin, A., McMahon, A., Mehta, H., Ooi, T. C., Perkins, D., Roy, L., Sapir, D., Tam, P., Bartaskova, D., Hemzsky, L., Kubina, D., Szabo, M., Tesar, V., Combe, C., Faller, B., Fauvel, J. P., Halimi, J. M., Hourmant, M., Le Meur, Y., Urena-Torres, P., Zaoui, P., Al-Sarraf, S., Burst, V., Degenhardt, S., Kempe, H. P., Kleophas, W., Kosch, C., Krumme, B., Kuhlmann, M., Pistrosch, F., Rambausek, M., Schmidt-Guertler, H., Segiet, T., Sommerer, C., Vielhauer, V., Wanner, C., Beberashvili, I., Benchetrit, S., Herskovits, T., Karnieli, E., Levin-Iaina, N., Mosenzon, O., Tsur, A., van Dijk, D. J., Wainstein, J., Yagil, Y., Yerushalmi, Y., Colussi, G., Conte, G., Di Luca, M., Giovambatista, C., Messa, P., Pani, A., Pisani, A., Rapana, M. R., Ruggenenti, P., Villa, G., Zoccali, C., Correa-Rotter, R., Diaz-Escobedo, S. L., Garcia, P., Gonzalez Galvez, G., Obrador Vera, G. T., Rico, R., Calero, F., Cigarran, S., de Alvaro, F., de Francisco, A. L., Egido, J., Fernandez, E., Fernandez Vega, F., Fort, J., Galan Serrano, A., Gorriz Teruel, J. L., Martinez, I., Martinez Castelao, A., Munar, M. A., Navarro, J., Nieto, J., Osuna, A., Pascual, J., Portoles, J., Praga, M., Vallés, M., Fellstrom, B., Frisenette-Fich, C., Hadimeri, H., Stenvinkel, P., Svensson, M., Weiss, L., Adamson, K., Dornhorst, A., El Kossi, M., Gnudi, L., Hendry, B., Johnson, A., Joseph, F., Kalra, P., Marshall, S., Mikhail, A., Myint, K. S., Soran, H., Taal, M., Zehnder, D., Abbott, L., Acharya, A., Ahmed, Z., Aiello, J., Akom, M., Ali, S., Alzohaili, O., Anderson, L., Anderson, S., Anger, M., Appel, G., Arakaki, R. F., Arif, A., Assefi, A. R., Atray, N., Awad, A., Barranco, E., Belledonne, M. O., Belo, D., Bernardo, M., Bernstein, R., Bhalla, V., Bhatia, D., Black, R. M., Block, G., Blondin, J., Blumenthal, S. S., Bononi, P., Brantley, R. R., Bresssler, P., Broumand, V., Brusco, O., Buerkert, J., Burgos-Calderon, R., Campbell, R., Canas, G., Cangiano, J., Cherlin, R., Chilakapati, V., Comunale, R., Coyne, D., Crawford, P. W., Darwish, R., Deeb, W., Denker, P. S., Desai, S., Desouza, C., Diamond, S., Dixon, B. S., Durham, J. H., Eisner, G., Elder, J. G., El-Shahawy, M., Fadda, G., Fitz-Patrick, D., Fonseca, V., Fraser, N. J., Frei, G., Fried, L., Galindo-Ramos, E., Germain, M., Ghantous, W., Gilbert, J. M., Gillum, D., Godwin, J., Goel, A., Goldfarb, DS., Graf, R. J., Greenwood, T., Guasch, A., Hanna, A., Harper, K., Herman, T., Hilton, T., Hines, T., Hoggard, J., Hootkins, R., Huseman, R., Israelit, A., Jamal, A., Kant, K., Kaptein, E., Kathresal, A., Kaupke, J., Kaveh, K., Kaye, W., Keightley, G. E., Keith, K., Khairullah, Q., Kondle, V., Kopyt, N., Krishna, G., Lawrence, M. K., LeBeau, M., Leehey, D. J., Levine, M. M., Levinson, D., Lew, S. Q., Lewis, D., Linfert, D., Liss, K., Lund, R., Madeleine, P., Mahmood, K., Martin, E. R., Martinez, C., Mayeda, S. O., Mendez, R., Middleton, J., Molitch, M. E., Moncrief, J., Moustafa, M., Muoneke, R., Murray, A. V., Murugan, T. S., Nammour, T. M., Nassar, G., Navaneethan, S., Newman, J., Nossuli, A., Nwakoby, I., Osama, S., Ouseph, R., Parker, J., Parnes, E., Patel, N., Pergola, P., Perlman, A., Perry, R. G., Petrillo, R., Prabhakar, S., Purighalla, R. S., Quesada-Suarez, L., Rabiei, A., Raskin, P., Rastogi, A., Reisin, E., Rekhi, A., Rivera-Colon, L., Rizk, D., Rodelas, R., Roer, D., Rosas, S., Ross, D. L., Rovner, S., Sackel, H., Sader, S., Santos, P., Schmidt, R., Shafik, S., Shakeel, M., Sharon, Z., Silva, A. L., Silva, A., Singh, B., Smith, M., Solomon, R., Soman, S., Spinowitz, B., Sprague, S. M., Spry, L., Stonesifer, L., Streja, D., Suchinda, P., Sun, C., Thakar, C. V., Trespalacios, F., Tumlin, J. A., Van Buren, P., Vernace, M., Vicks, S., Warren, M., Weiss, D., Welker, J., Winston, J. A., Wombolt, D. G., Wood, M., Wu, M., Wynne, A., Yu, H. & Zabaneh, R. I., 2013, In: New England Journal of Medicine. 369, 26, p. 2492-2503 12 p.

    Research output: Contribution to journal › Article › peer-review

    542 Scopus citations

  • Genome-wide association analysis confirms and extends the association of SLC2A9 with serum uric acid levels to mexican americans

    Voruganti, V. S., Kent, J. W., Debnath, S., Cole, S. A., Haack, K., Göring, H. H. H., Carless, M. A., Curran, J. E., Johnson, M. P., Almasy, L., Dyer, T. D., MacCluer, J. W., Moses, E. K., Abboud, H. E., Mahaney, M. C., Blangero, J. & Comuzzie, A. G., 2013, In: Frontiers in Genetics. 4, DEC, 00279.

    Research output: Contribution to journal › Article › peer-review

    24 Scopus citations

  • Improving learning about familial risks using a multicomponent approach: the GRACE program

    Arar, N., Delgado, E., Lee, S. & Abboud, H. E., Jan 1 2013, In: Personalized Medicine. 10, 1, p. 35-44 10 p.

    Research output: Contribution to journal › Article › peer-review

    4 Scopus citations

  • Mammalian target of rapamycin regulates nox4-Mediated podocyte depletion in diabetic renal injury

    Eid, A. A., Ford, B. M., Bhandary, B., Cavaglieri, R. D. C., Block, K., Barnes, J. L., Gorin, Y., Choudhury, G. G. & Abboud, H. E., Aug 2013, In: Diabetes. 62, 8, p. 2935-2947 13 p.

    Research output: Contribution to journal › Article › peer-review

    96 Scopus citations

  • NFκB-mediated cyclin D1 expression by microRNA-21 influences renal cancer cell proliferation

    Bera, A., Ghosh-Choudhury, N., Dey, N., Das, F., Kasinath, B. S., Abboud, H. E. & Choudhury, G. G., Dec 2013, In: Cellular Signalling. 25, 12, p. 2575-2586 12 p.

    Research output: Contribution to journal › Article › peer-review

    37 Scopus citations

  • Susceptibility gene search for nephropathy and related traits in Mexican-Americans

    Thameem, F., Kawalit, I. A., Adler, S. G. & Abboud, H. E., Oct 2013, In: Molecular Biology Reports. 40, 10, p. 5769-5779 11 p.

    Research output: Contribution to journal › Article › peer-review

    6 Scopus citations

  • Synthetic oleanane triterpenoids: Magic bullets or not?

    Abboud, H. E., May 2013, In: Kidney international. 83, 5, p. 785-787 3 p.

    Research output: Contribution to journal › Comment/debate › peer-review

    11 Scopus citations

  • The antioxidant silybin prevents high glucose-induced oxidative stress and podocyte injury in vitro and in vivo

    Khazim, K., Gorin, Y., Cavaglieri, R. C., Abboud, H. E. & Fanti, P., Sep 1 2013, In: American Journal of Physiology - Renal Physiology. 305, 5, p. F691-F700

    Research output: Contribution to journal › Article › peer-review

    73 Scopus citations

  • Transforming growth factor β integrates Smad 3 to mechanistic target of rapamycin complexes to arrest deptor abundance for glomerular mesangial cell hypertrophy

    Das, F., Ghosh-Choudhury, N., Bera, A., Dey, N., Abboud, H. E., Kasinath, B. S. & Choudhury, G. G., Mar 15 2013, In: Journal of Biological Chemistry. 288, 11, p. 7756-7768 13 p.

    Research output: Contribution to journal › Article › peer-review

    27 Scopus citations
  • 2012

    Diabetic nephropathy among Mexican Americans

    Debnath, S., Thameem, F., Alves, T., Nolen, J., Hania, A. S., Bansal, S., Abboud, H. E. & Fanti, P., Apr 2012, In: Clinical Nephrology. 77, 4, p. 332-344 13 p.

    Research output: Contribution to journal › Article › peer-review

    10 Scopus citations

  • Genetic association and gene-gene interaction analyses in African American dialysis patients with nondiabetic nephropathy

    Bostrom, M. A., Kao, W. H. L., Li, M., Abboud, H. E., Adler, S. G., Iyengar, S. K., Kimmel, P. L., Hanson, R. L., Nicholas, S. B., Rasooly, R. S., Sedor, J. R., Coresh, J., Kohn, O. F., Leehey, D. J., Thornley-Brown, D., Bottinger, E. P., Lipkowitz, M. S., Meoni, L. A., Klag, M. J., Lu, L. & 5 others, Hicks, P. J., Langefeld, C. D., Parekh, R. S., Bowden, D. W. & Freedman, B. I., Feb 2012, In: American Journal of Kidney Diseases. 59, 2, p. 210-221 12 p.

    Research output: Contribution to journal › Article › peer-review

    30 Scopus citations

  • Hydrogen sulfide inhibits high glucose-induced matrix protein synthesis by activating AMP-activated protein kinase in renal epithelial cells

    Lee, H. J., Mariappan, M. M., Feliers, D., Cavaglieri, R. C., Sataranatarajan, K., Abboud, H. E., Choudhury, G. G. & Kasinath, B. S., Feb 10 2012, In: Journal of Biological Chemistry. 287, 7, p. 4451-4461 11 p.

    Research output: Contribution to journal › Article › peer-review

    81 Scopus citations

  • IGF-I increases the expression of fibronectin by Nox4-dependent Akt phosphorylation in renal tubular epithelial cells

    New, D. D., Block, K., Bhandhari, B., Gorin, Y. & Abboud, H. E., Jan 2012, In: American Journal of Physiology - Cell Physiology. 302, 1, p. C122-C130

    Research output: Contribution to journal › Article › peer-review

    42 Scopus citations