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  • Babatunde Oyajobi

A niche-dependent myeloid transcriptome signature defines dormant myeloma cells

Khoo, W. H., Ledergor, G., Weiner, A., Roden, D. L., Terry, R. L., McDonald, M. M., Chai, R. C., De Veirman, K., Owen, K. L., Opperman, K. S., Vandyke, K., Clark, J. R., Seckinger, A., Kovacic, N., Nguyen, A., Mohanty, S. T., Pettitt, J. A., Xiao, Y., Corr, A. P., Seeliger, C. & 14 others, Novotny, M., Lasken, R. S., Nguyen, T. V., Oyajobi, B. O., Aftab, D., Swarbrick, A., Parker, B., Hewett, D. R., Hose, D., Vanderkerken, K., Zannettino, A. C. W., Amit, I., Phan, T. G. & Croucher, P. I., Jul 4 2019, In : Blood. 134, 1, p. 30-43 14 p.

Research output: Contribution to journalArticle

12 Scopus citations

Synthesis of a bone-targeted bortezomib with in vivo anti-myeloma effects in mice

Wang, H., Xiao, L., Tao, J., Srinivasan, V., Boyce, B. F., Ebetino, F. H., Oyajobi, B. O., Boeckman, R. K. & Xing, L., Sep 10 2018, In : Pharmaceutics. 10, 3, 154.

Research output: Contribution to journalArticle

6 Scopus citations

Inhibiting the osteocyte-specific protein sclerostin increases bone mass and fracture resistance in multiple myeloma

McDonald, M. M., Reagan, M. R., Youlten, S. E., Mohanty, S. T., Seckinger, A., Terry, R. L., Pettitt, J. A., Simic, M. K., Cheng, T. L., Morse, A., Le, L. M. T., Abi-Hanna, D., Kramer, I., Falank, C., Fairfield, H., Ghobrial, I. M., Baldock, P. A., Little, D. G., Kneissel, M., Vanderkerken, K. & 6 others, Bassett, J. H. D., Williams, G. R., Oyajobi, B. O., Hose, D., Phan, T. G. & Croucher, P. I., Jun 29 2017, In : Blood. 129, 26, p. 3452-3464 13 p.

Research output: Contribution to journalArticle

55 Scopus citations

Combined treatment with a transforming growth factor beta inhibitor (1D11) and bortezomib improves bone architecture in a mouse model of myeloma-induced bone disease

Nyman, J. S., Merkel, A. R., Uppuganti, S., Nayak, B., Rowland, B., Makowski, A. J., Oyajobi, B. & Sterling, J. A., Oct 1 2016, In : Bone. 91, p. 81-91 11 p.

Research output: Contribution to journalArticle

17 Scopus citations

A dominant-negative F-box deleted mutant of E3 ubiquitin ligase, β-TrCP1/FWD1, markedly reduces myeloma cell growth and survival in mice

Sharma, R., Williams, P. J., Gupta, A., McCluskey, B., Bhaskaran, S., Muñoz, S. & Oyajobi, B. O., 2015, In : Oncotarget. 6, 25, p. 21589-21602 14 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Multiple myeloma induces Mcl-1 expression and survival of myeloid-derived suppressor cells

de Veirman, K., van Ginderachter, J. A., Lub, S., de Beule, N., Thielemans, K., Bautmans, I., Oyajobi, B. O., de Bruyne, E., Menu, E., Lemaire, M., van Riet, I., Vanderkerken, K. & van Valckenborgh, E., 2015, In : Oncotarget. 6, 12, p. 10532-10547 16 p.

Research output: Contribution to journalArticle

Open Access
31 Scopus citations

PD-L1/PD-1 presence in the tumor microenvironment and activity of PD-1 blockade in multiple myeloma

Paiva, B., Azpilikueta, A., Puig, N., Ocio, E. M., Sharma, R., Oyajobi, B. O., Labiano, S., San-Segundo, L., Rodriguez, A., Aires-Mejia, I., Rodriguez, I., Escalante, F., De Coca, A. G., Barez, A., San Miguel, J. F. & Melero, I., Oct 1 2015, In : Leukemia. 29, 10, p. 2110-2113 4 p.

Research output: Contribution to journalLetter

97 Scopus citations

PKA/AMPK signaling in relation to adiponectin's antiproliferative effect on multiple myeloma cells

Medina, E. A., Oberheu, K., Polusani, S. R., Ortega, V., Velagaleti, G. V. N. & Oyajobi, B. O., Oct 1 2014, In : Leukemia. 28, 10, p. 2080-2089 10 p.

Research output: Contribution to journalArticle

49 Scopus citations

Wnt/β-catenin signaling activates bone morphogenetic protein 2 expression in osteoblasts

Zhang, R., Oyajobi, B. O., Harris, S. E., Chen, D., Tsao, C., Deng, H. W. & Zhao, M., Jan 2013, In : Bone. 52, 1, p. 145-156 12 p.

Research output: Contribution to journalArticle

161 Scopus citations

CCR1 blockade reduces tumor burden and osteolysis in vivo in a mouse model of myeloma bone disease

Dairaghi, D. J., Oyajobi, B. O., Gupta, A., McCluskey, B., Miao, S., Powers, J. P., Seitz, L. C., Wang, Y., Zeng, Y., Zhang, P., Schall, T. J. & Jaen, J. C., Aug 16 2012, In : Blood. 120, 7, p. 1449-1457 9 p.

Research output: Contribution to journalArticle

39 Scopus citations

Functional redundancy of type II BMP receptor and type IIB activin receptor in BMP2-induced osteoblast differentiation

Liu, H., Zhang, R., Chen, D., Oyajobi, B. O. & Zhao, M., Mar 2012, In : Journal of Cellular Physiology. 227, 3, p. 952-963 12 p.

Research output: Contribution to journalArticle

25 Scopus citations
38 Scopus citations

Reovirus therapy stimulates endoplasmic reticular stress, NOXA induction, and augments bortezomib-mediated apoptosis in multiple myeloma

Kelly, K. R., Espitia, C. M., Mahalingam, D., Oyajobi, B. O., Coffey, M., Giles, F. J., Carew, J. S. & Nawrocki, S. T., Jun 21 2012, In : Oncogene. 31, 25, p. 3023-3038 16 p.

Research output: Contribution to journalArticle

42 Scopus citations