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  • Babatunde Oyajobi

A niche-dependent myeloid transcriptome signature defines dormant myeloma cells

Khoo, W. H., Ledergor, G., Weiner, A., Roden, D. L., Terry, R. L., McDonald, M. M., Chai, R. C., De Veirman, K., Owen, K. L., Opperman, K. S., Vandyke, K., Clark, J. R., Seckinger, A., Kovacic, N., Nguyen, A., Mohanty, S. T., Pettitt, J. A., Xiao, Y., Corr, A. P., Seeliger, C. & 14 others, Novotny, M., Lasken, R. S., Nguyen, T. V., Oyajobi, B. O., Aftab, D., Swarbrick, A., Parker, B., Hewett, D. R., Hose, D., Vanderkerken, K., Zannettino, A. C. W., Amit, I., Phan, T. G. & Croucher, P. I., Jul 4 2019, In : Blood. 134, 1, p. 30-43 14 p.

Research output: Contribution to journalArticle

12 Scopus citations

Synthesis of a bone-targeted bortezomib with in vivo anti-myeloma effects in mice

Wang, H., Xiao, L., Tao, J., Srinivasan, V., Boyce, B. F., Ebetino, F. H., Oyajobi, B. O., Boeckman, R. K. & Xing, L., Sep 10 2018, In : Pharmaceutics. 10, 3, 154.

Research output: Contribution to journalArticle

6 Scopus citations

Inhibiting the osteocyte-specific protein sclerostin increases bone mass and fracture resistance in multiple myeloma

McDonald, M. M., Reagan, M. R., Youlten, S. E., Mohanty, S. T., Seckinger, A., Terry, R. L., Pettitt, J. A., Simic, M. K., Cheng, T. L., Morse, A., Le, L. M. T., Abi-Hanna, D., Kramer, I., Falank, C., Fairfield, H., Ghobrial, I. M., Baldock, P. A., Little, D. G., Kneissel, M., Vanderkerken, K. & 6 others, Bassett, J. H. D., Williams, G. R., Oyajobi, B. O., Hose, D., Phan, T. G. & Croucher, P. I., Jun 29 2017, In : Blood. 129, 26, p. 3452-3464 13 p.

Research output: Contribution to journalArticle

55 Scopus citations

Combined treatment with a transforming growth factor beta inhibitor (1D11) and bortezomib improves bone architecture in a mouse model of myeloma-induced bone disease

Nyman, J. S., Merkel, A. R., Uppuganti, S., Nayak, B., Rowland, B., Makowski, A. J., Oyajobi, B. & Sterling, J. A., Oct 1 2016, In : Bone. 91, p. 81-91 11 p.

Research output: Contribution to journalArticle

17 Scopus citations

A dominant-negative F-box deleted mutant of E3 ubiquitin ligase, β-TrCP1/FWD1, markedly reduces myeloma cell growth and survival in mice

Sharma, R., Williams, P. J., Gupta, A., McCluskey, B., Bhaskaran, S., Muñoz, S. & Oyajobi, B. O., 2015, In : Oncotarget. 6, 25, p. 21589-21602 14 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Multiple myeloma induces Mcl-1 expression and survival of myeloid-derived suppressor cells

de Veirman, K., van Ginderachter, J. A., Lub, S., de Beule, N., Thielemans, K., Bautmans, I., Oyajobi, B. O., de Bruyne, E., Menu, E., Lemaire, M., van Riet, I., Vanderkerken, K. & van Valckenborgh, E., 2015, In : Oncotarget. 6, 12, p. 10532-10547 16 p.

Research output: Contribution to journalArticle

Open Access
31 Scopus citations

PD-L1/PD-1 presence in the tumor microenvironment and activity of PD-1 blockade in multiple myeloma

Paiva, B., Azpilikueta, A., Puig, N., Ocio, E. M., Sharma, R., Oyajobi, B. O., Labiano, S., San-Segundo, L., Rodriguez, A., Aires-Mejia, I., Rodriguez, I., Escalante, F., De Coca, A. G., Barez, A., San Miguel, J. F. & Melero, I., Oct 1 2015, In : Leukemia. 29, 10, p. 2110-2113 4 p.

Research output: Contribution to journalLetter

97 Scopus citations

PKA/AMPK signaling in relation to adiponectin's antiproliferative effect on multiple myeloma cells

Medina, E. A., Oberheu, K., Polusani, S. R., Ortega, V., Velagaleti, G. V. N. & Oyajobi, B. O., Oct 1 2014, In : Leukemia. 28, 10, p. 2080-2089 10 p.

Research output: Contribution to journalArticle

49 Scopus citations

Wnt/β-catenin signaling activates bone morphogenetic protein 2 expression in osteoblasts

Zhang, R., Oyajobi, B. O., Harris, S. E., Chen, D., Tsao, C., Deng, H. W. & Zhao, M., Jan 2013, In : Bone. 52, 1, p. 145-156 12 p.

Research output: Contribution to journalArticle

161 Scopus citations

Bone marrow-targeted liposomal carriers

Sou, K., Goins, B., Oyajobi, B. O., Travi, B. L. & Phillips, W. T., Mar 2011, In : Expert Opinion on Drug Delivery. 8, 3, p. 317-328 12 p.

Research output: Contribution to journalReview article

27 Scopus citations

Microtubule assembly affects bone mass by regulating both osteoblast and osteoclast functions: Stathmin deficiency produces an osteopenic phenotype in mice

Liu, H., Zhang, R., Ko, S. Y., Oyajobi, B. O., Papasian, C. J., Deng, H. W., Zhang, S. & Zhao, M., Sep 2011, In : Journal of Bone and Mineral Research. 26, 9, p. 2052-2067 16 p.

Research output: Contribution to journalArticle

10 Scopus citations

TGF-β promotion of Gli2-induced expression of parathyroid hormone-related protein, an important osteolytic factor in bone metastasis, is independent of canonical Hedgehog signaling

Johnson, R. W., Nguyen, M. P., Padalecki, S. S., Grubbs, B. G., Merkel, A. R., Oyajobi, B. O., Matrisian, L. M., Mundy, G. R. & Sterling, J. A., Feb 1 2011, In : Cancer Research. 71, 3, p. 822-831 10 p.

Research output: Contribution to journalArticle

123 Scopus citations

Transcriptional regulation of BMP2 expression by the PTH-CREB signaling pathway in osteoblasts

Zhang, R., Edwards, J. R., Ko, S. Y., Dong, S., Liu, H., Oyajobi, B. O., Papasian, C., Deng, H. W. & Zhao, M., 2011, In : PloS one. 6, 6, e20780.

Research output: Contribution to journalArticle

46 Scopus citations