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  • Ravindranath Duggirala
2020

A structural variation reference for medical and population genetics

Genome Aggregation Database Consortium & Genome Aggregation Database Production Team, May 28 2020, In : Nature. 581, 7809, p. 444-451 8 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals

Genome Aggregation Database Production Team & Genome Aggregation Database Consortium, Dec 1 2020, In : Nature communications. 11, 1, 2523.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Evaluating drug targets through human loss-of-function genetic variation

Genome Aggregation Database Production Team & Genome Aggregation Database Consortium, May 28 2020, In : Nature. 581, 7809, p. 459-464 6 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes

Genome Aggregation Database Production Team & Genome Aggregation Database Consortium, Dec 1 2020, In : Nature communications. 11, 1, 2539.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Minimal Relationship between Local Gyrification and General Cognitive Ability in Humans

Mathias, S. R., Knowles, E. E. M., Mollon, J., Rodrigue, A., Koenis, M. M. C., Alexander-Bloch, A. F., Winkler, A. M., Olvera, R. L., Duggirala, R., Göring, H. H. H., Curran, J. E., Fox, P. T., Almasy, L., Blangero, J. & Glahn, D. C., May 18 2020, In : Cerebral Cortex. 30, 6, p. 3439-3450 12 p.

Research output: Contribution to journalArticle

Neurocognitive impairment in type 2 diabetes: evidence for shared genetic aetiology

Mollon, J., Curran, J. E., Mathias, S. R., Knowles, E. E. M., Carlisle, P., Fox, P. T., Olvera, R. L., Göring, H. H. H., Rodrigue, A., Almasy, L., Duggirala, R., Blangero, J. & Glahn, D. C., May 1 2020, In : Diabetologia. 63, 5, p. 977-986 10 p.

Research output: Contribution to journalArticle

Open Access

Rapid, Phase-free Detection of Long Identity-by-Descent Segments Enables Effective Relationship Classification

Seidman, D. N., Shenoy, S. A., Kim, M., Babu, R., Woods, I. G., Dyer, T. D., Lehman, D. M., Curran, J. E., Duggirala, R., Blangero, J. C. & Williams, A. L., Apr 2 2020, In : American Journal of Human Genetics. 106, 4, p. 453-466 14 p.

Research output: Contribution to journalArticle

Open Access

The effect of LRRK2 loss-of-function variants in humans

Genome Aggregation Database Production Team, Genome Aggregation Database Consortium & 23andMe Research Team, 2020, (Accepted/In press) In : Nature Medicine.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

The mutational constraint spectrum quantified from variation in 141,456 humans

Genome Aggregation Database Consortium, May 28 2020, In : Nature. 581, 7809, p. 434-443 10 p.

Research output: Contribution to journalArticle

Open Access
29 Scopus citations

Transcript expression-aware annotation improves rare variant interpretation

Genome Aggregation Database Production Team & Genome Aggregation Database Consortium, May 28 2020, In : Nature. 581, 7809, p. 452-458 7 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
2019

A QTL on chromosome 3q23 influences processing speed in humans

Knowles, E. E. M., Mathias, S. R., Mollon, J., Rodrigue, A., Koenis, M. M. G., Dyer, T. D., Goring, H. H. H., Curran, J. E., Olvera, R. L., Duggirala, R., Almasy, L. A., Blangero, J. C. & Glahn, D. C., Apr 2019, In : Genes, Brain and Behavior. 18, 4, e12530.

Research output: Contribution to journalArticle

Crossover interference and sex-specific genetic maps shape identical by descent sharing in close relatives

Caballero, M., Seidman, D. N., Qiao, Y., Sannerud, J., Dyer, T. D., Lehman, D. M., Curran, J. E., Duggirala, R., Blangero, J. C., Carmi, S. & Williams, A. L., Jan 1 2019, In : PLoS Genetics. 15, 12, e1007979.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Evidence for genetic correlation between human cerebral white matter microstructure and inflammation

Rodrigue, A. L., Knowles, E. E. M., Mollon, J., Mathias, S. R., Koenis, M. M. G., Peralta, J. M., Leandro, A. C., Fox, P. T., Sprooten, E., Kochunov, P., Olvera, R. L., Duggirala, R., Almasy, L. A., Curran, J. E., Blangero, J. C. & Glahn, D. C., Jan 1 2019, In : Human Brain Mapping. 40, 14, p. 4180-4191 12 p.

Research output: Contribution to journalArticle

Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls

Broad Genomics Platform, DiscovEHR Collaboration, CHARGE, LuCamp, ProDiGY, GoT2D, ESP, SIGMA-T2D, T2D-GENES & AMP-T2D-GENES, Jun 6 2019, In : Nature. 570, 7759, p. 71-76 6 p.

Research output: Contribution to journalArticle

Open Access
33 Scopus citations

Family-based analyses reveal novel genetic overlap between cytokine interleukin-8 and risk for suicide attempt

Knowles, E. E. M., Curran, J. E., Göring, H. H. H., Mathias, S. R., Mollon, J., Rodrigue, A., Olvera, R. L., Leandro, A., Duggirala, R., Almasy, L. A., Blangero, J. C. & Glahn, D. C., Aug 2019, In : Brain, Behavior, and Immunity. 80, p. 292-299 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Human Cortical Thickness Organized into Genetically-determined Communities across Spatial Resolutions

Alexander-Bloch, A. F., Mathias, S. R., Fox, P. T., Olvera, R. L., Göring, H. H. H., Duggirala, R., Curran, J. E., Blangero, J. C. & Glahn, D. C., Jan 1 2019, In : Cerebral Cortex. 29, 1, p. 106-118 13 p.

Research output: Contribution to journalArticle

3 Scopus citations

JC viruria is associated with reduced risk of diabetic kidney disease

Family Investigation of Nephropathy and Diabetes (FIND Consortium), Jun 1 2019, In : Journal of Clinical Endocrinology and Metabolism. 104, 6, p. 2286-2294 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Rare DEGS1 variant significantly alters de novo ceramide synthesis pathway

Blackburn, N. B., Michael, L. F., Meikle, P. J., Peralta, J. M., Mosior, M., McAhren, S., Bui, H. H., Bellinger, M. A., Giles, C., Kumar, S., Leandro, A. C., Almeida, M., Weir, J. M., Mahaney, M. C., Dyer, T. D., Almasy, L., VandeBerg, J. L., Williams-Blangero, S., Glahn, D. C., Duggirala, R. & 3 others, Kowala, M., Blangero, J. & Curran, J. E., 2019, In : Journal of lipid research. 60, 9, p. 1630-1639 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Whole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children With Asthma

National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Consortium, Dec 2019, In : Chest. 156, 6, p. 1068-1079 12 p.

Research output: Contribution to journalArticle

2 Scopus citations
2018

A genetic association study of carotid intima-media thickness (CIMT) and plaque in Mexican Americans and European Americans with rheumatoid arthritis

Arya, R., Escalante, A., Farook, V. S., Restrepo, J. F., Battafarano, D. F., Almeida, M., Kos, M. Z., Fourcaudot, M. J., Mummidi, S., Kumar, S., Curran, J. E., Jenkinson, C. P., Blangero, J., Duggirala, R. & del Rincon, I., Apr 2018, In : Atherosclerosis. 271, p. 92-101 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Clinical Significance of Serum Uric Acid Levels in Mexican Young Adults

Alegría-DÍaz, A., Valdez-Ortiz, R., Murguía-Romero, M., Jiménez-Flores, R., Villalobos-Molina, R., Mummidi, S., Duggirala, R., López-Alvarenga, J. C. & Pérez-Navarro, M., Jan 1 2018, In : Contributions to nephrology. 192, p. 125-134 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Data on genetic associations of carotid atherosclerosis markers in Mexican American and European American rheumatoid arthritis subjects

Arya, R., Escalante, A., Farook, V. S., Restrepo, J. F., Battafarano, D. F., Almeida, M., Kos, M. Z., Fourcaudot, M. J., Mummidi, S., Kumar, S., Curran, J. E., Jenkinson, C. P., Blangero, J., Duggirala, R. & del Rincon, I., Apr 2018, In : Data in Brief. 17, p. 820-829 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

NHLBI TOPMed Lipids Working Group, Dec 1 2018, In : Nature communications. 9, 1, 3391.

Research output: Contribution to journalArticle

37 Scopus citations

Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

Zekavat, S. M., Ruotsalainen, S., Handsaker, R. E., Alver, M., Bloom, J., Poterba, T., Seed, C., Ernst, J., Chaffin, M., Engreitz, J., Peloso, G. M., Manichaikul, A., Yang, C., Ryan, K. A., Fu, M., Johnson, W. C., Tsai, M., Budoff, M., Ramachandran, V. S., Cupples, L. A. & 323 others, Rotter, J. I., Rich, S. S., Post, W., Mitchell, B. D., Correa, A., Metspalu, A., Wilson, J. G., Salomaa, V., Kellis, M., Daly, M. J., Neale, B. M., McCarroll, S., Surakka, I., Esko, T., Ganna, A., Ripatti, S., Kathiresan, S., Natarajan, P., Abe, N., Abecasis, G., Albert, C., Allred, N. P., Almasy, L., Alonso, A., Ament, S., Anderson, P., Anugu, P., Applebaum-Bowden, D., Arking, D., Arnett, D. K., Ashley-Koch, A., Aslibekyan, S., Assimes, T., Auer, P., Avramopoulos, D., Barnard, J., Barnes, K., Barr, R. G., Barron-Casella, E., Beaty, T., Becker, D., Becker, L., Beer, R., Begum, F., Beitelshees, A., Benjamin, E., Bezerra, M., Bielak, L., Bis, J., Blackwell, T., Blangero, J., Boerwinkle, E., Borecki, I., Bowler, R., Brody, J., Broeckel, U., Broome, J., Bunting, K., Burchard, E., Cardwell, J., Carty, C., Casaburi, R., Casella, J., Chang, C., Chasman, D., Chavan, S., Chen, B. J., Chen, W. M., Chen, Y. D. I., Cho, M., Choi, S. H., Chuang, L. M., Chung, M., Cornell, E., Crandall, C., Crapo, J., Curran, J., Curtis, J., Custer, B., Damcott, C., Darbar, D., Das, S., David, S., Davis, C., Daya, M., Andrade, M. D., Debaun, M., Deka, R., Demeo, D., Devine, S., Do, R., Duan, Q., Duggirala, R., Durda, P., Dutcher, S., Eaton, C., Ekunwe, L., Ellinor, P., Emery, L., Farber, C., Farnam, L., Fingerlin, T., Flickinger, M., Fornage, M., Franceschini, N., Fullerton, S. M., Fulton, L., Gabriel, S., Gan, W., Gao, Y., Gass, M., Gelb, B., Geng, X., Germer, S., Gignoux, C., Gladwin, M., Glahn, D., Gogarten, S., Gong, D. W., Goring, H., Gu, C. C., Guan, Y., Guo, X., Haessler, J., Hall, M., Harris, D., Hawley, N., He, J., Heavner, B., Heckbert, S., Hernandez, R., Herrington, D., Hersh, C., Hidalgo, B., Hixson, J., Hokanson, J., Hong, E., Hoth, K., Hsiung, C., Huston, H., Hwu, C. M., Irvin, M. R., Jackson, R., Jain, D., Jaquish, C., Jhun, M. A., Johnsen, J., Johnson, A., Johnston, R., Jones, K., Kang, H. M., Kaplan, R., Kardia, S., Kaufman, L., Kelly, S., Kenny, E., Kessler, M., Khan, A., Kinney, G., Konkle, B., Kooperberg, C., Kramer, H., Krauter, S., Lange, C., Lange, E., Lange, L., Laurie, C., Laurie, C., Leboff, M., Lee, S. S., Lee, W. J., Lefaive, J., Levine, D., Levy, D., Lewis, J., Li, Y., Lin, H., Lin, K. H., Liu, S., Liu, Y., Loos, R., Lubitz, S., Lunetta, K., Luo, J., Mahaney, M., Make, B., Manson, J. A., Margolin, L., Martin, L., Mathai, S., Mathias, R., McArdle, P., McDonald, M. L., McFarland, S., McGarvey, S., Mei, H., Meyers, D. A., Mikulla, J., Min, N., Minear, M., Minster, R. L., Montasser, M. E., Musani, S., Mwasongwe, S., Mychaleckyj, J. C., Nadkarni, G., Naik, R., Nekhai, S., Nickerson, D., North, K., O'connell, J., O'connor, T., Ochs-Balcom, H., Pankow, J., Papanicolaou, G., Parker, M., Parsa, A., Penchev, S., Peralta, J. M., Perez, M., Perry, J., Peters, U., Peyser, P., Phillips, L., Phillips, S., Pollin, T., Becker, J. P., Boorgula, M. P., Preuss, M., Prokopenko, D., Psaty, B., Qasba, P., Qiao, D., Qin, Z., Rafaels, N., Raffield, L., Rao, D. C., Rasmussen-Torvik, L., Ratan, A., Redline, S., Reed, R., Regan, E., Reiner, A., Rice, K., Roden, D., Roselli, C., Ruczinski, I., Russell, P., Ruuska, S., Sakornsakolpat, P., Salimi, S., Salzberg, S., Sandow, K., Sankaran, V., Scheller, C., Schmidt, E., Schwander, K., Schwartz, D., Sciurba, F., Seidman, C., Sheehan, V., Shetty, A., Shetty, A., Sheu, W. H. H., Shoemaker, M. B., Silver, B., Silverman, E., Smith, J., Smith, J., Smith, N., Smith, T., Smoller, S., Snively, B., Sofer, T., Sotoodehnia, N., Stilp, A., Streeten, E., Sung, Y. J., Sylvia, J., Szpiro, A., Sztalryd, C., Taliun, D., Tang, H., Taub, M., Taylor, K., Taylor, S., Telen, M., Thornton, T. A., Tinker, L., Tirschwell, D., Tiwari, H., Tracy, R., Vaidya, D., Vandehaar, P., Vrieze, S., Walker, T., Wallace, R., Walts, A., Wan, E., Wang, F. F., Watson, K., Weeks, D. E., Weir, B., Weiss, S., Weng, L. C., Willer, C., Williams, K., Williams, L. K., Wilson, C., Wong, Q., Xu, H., Yanek, L., Yang, I., Yang, R., Zaghloul, N., Zhang, Y., Zhao, S. X., Zhao, W., Zheng, X., Zhi, D., Zhou, X., Zody, M. & Zoellner, S., Dec 1 2018, In : Nature communications. 9, 1, 2606.

Research output: Contribution to journalArticle

17 Scopus citations

Disentangling the genetic overlap between cholesterol and suicide risk

Knowles, E. E. M., Curran, J. E., Meikle, P. J., Huynh, K., Mathias, S. R., Göring, H. H. H., VandeBerg, J. L., Mahaney, M. C., Jalbrzikowski, M., Mosior, M. K., Michael, L. F., Olvera, R. L., Duggirala, R., Almasy, L., Glahn, D. C. & Blangero, J., Dec 1 2018, In : Neuropsychopharmacology. 43, 13, p. 2556-2563 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

Flannick, J., Fuchsberger, C., Mahajan, A., Teslovich, T. M., Agarwala, V., Gaulton, K. J., Caulkins, L., Koesterer, R., Ma, C., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Tajes, J. F. & 281 others, Highland, H. M., Dupuis, J., Chines, P. S., Lindgren, C. M., Hartl, C., Jackson, A. U., Chen, H., Huyghe, J. R., van de Bunt, M., Pearson, R. D., Kumar, A., Müller-Nurasyid, M., Grarup, N., Stringham, H. M., Gamazon, E. R., Lee, J., Chen, Y., Scott, R. A., Below, J. E., Chen, P., Huang, J., Go, M. J., Stitzel, M. L., Pasko, D., Parker, S. C. J., Varga, T. V., Green, T., Beer, N. L., Day-Williams, A. G., Ferreira, T., Fingerlin, T., Horikoshi, M., Hu, C., Huh, I., Ikram, M. K., Kim, B. J., Kim, Y., Kim, Y. J., Kwon, M. S., Lee, J., Lee, S., Lin, K. H., Maxwell, T. J., Nagai, Y., Wang, X., Welch, R. P., Yoon, J., Zhang, W., Barzilai, N., Voight, B. F., Han, B. G., Jenkinson, C. P., Kuulasmaa, T., Kuusisto, J., Manning, A., Ng, M. C. Y., Palmer, N. D., Balkau, B., Stančáková, A., Abboud, H. E., Boeing, H., Giedraitis, V., Prabhakaran, D., Gottesman, O., Scott, J., Carey, J., Kwan, P., Grant, G., Smith, J. D., Neale, B. M., Purcell, S., Butterworth, A. S., Howson, J. M. M., Lee, H. M., Lu, Y., Kwak, S. H., Zhao, W., Danesh, J., Lam, V. K. L., Park, K. S., Saleheen, D., So, W. Y., Tam, C. H. T., Afzal, U., Aguilar, D., Arya, R., Aung, T., Chan, E., Navarro, C., Cheng, C. Y., Palli, D., Correa, A., Curran, J. E., Rybin, D., Farook, V. S., Fowler, S. P., Freedman, B. I., Griswold, M., Hale, D. E., Hicks, P. J., Khor, C. C., Kumar, S., Lehne, B., Thuillier, D., Lim, W. Y., Liu, J., Loh, M., Musani, S. K., Puppala, S., Scott, W. R., Yengo, L., Tan, S. T., Taylor, H. A., Thameem, F., Wilson, G., Wong, T. Y., Njølstad, P. R., Levy, J. C., Mangino, M., Bonnycastle, L. L., Schwarzmayr, T., Fadista, J., Surdulescu, G. L., Herder, C., Groves, C. J., Wieland, T., Bork-Jensen, J., Brandslund, I., Christensen, C., Koistinen, H. A., Doney, A. S. F., Kinnunen, L., Esko, T., Farmer, A. J., Hakaste, L., Hodgkiss, D., Kravic, J., Lyssenko, V., Hollensted, M., Jørgensen, M. E., Jørgensen, T., Ladenvall, C., Justesen, J. M., Käräjämäki, A., Kriebel, J., Rathmann, W., Lannfelt, L., Lauritzen, T., Narisu, N., Linneberg, A., Melander, O., Milani, L., Neville, M., Orho-Melander, M., Qi, L., Qi, Q., Roden, M., Rolandsson, O., Swift, A., Rosengren, A. H., Stirrups, K., Wood, A. R., Mihailov, E., Blancher, C., Carneiro, M. O., Maguire, J., Poplin, R., Shakir, K., Fennell, T., DePristo, M., de Angelis, M. H., Deloukas, P., Gjesing, A. P., Jun, G., Nilsson, P., Murphy, J., Onofrio, R., Thorand, B., Hansen, T., Meisinger, C., Hu, F. B., Isomaa, B., Karpe, F., Liang, L., Peters, A., Huth, C., O'Rahilly, S. P., Palmer, C. N. A., Pedersen, O., Rauramaa, R., Tuomilehto, J., Salomaa, V., Watanabe, R. M., Syvänen, A. C., Bergman, R. N., Bharadwaj, D., Bottinger, E. P., Cho, Y. S., Chandak, G. R., Chan, J. C. N., Chia, K. S., Daly, M. J., Ebrahim, S. B., Langenberg, C., Elliott, P., Jablonski, K. A., Lehman, D. M., Jia, W., Ma, R. C. W., Pollin, T. I., Sandhu, M., Tandon, N., Froguel, P., Barroso, I., Teo, Y. Y., Zeggini, E., Loos, R. J. F., Small, K. S., Ried, J. S., DeFronzo, R. A., Grallert, H., Glaser, B., Metspalu, A., Wareham, N. J., Walker, M., Banks, E., Gieger, C., Ingelsson, E., Im, H. K., Illig, T., Franks, P. W., Buck, G., Trakalo, J., Buck, D., Prokopenko, I., Mägi, R., Lind, L., Farjoun, Y., Owen, K. R., Gloyn, A. L., Strauch, K., Tuomi, T., Kooner, J. S., Lee, J. Y., Park, T., Donnelly, P., Morris, A. D., Hattersley, A. T., Bowden, D. W., Collins, F. S., Atzmon, G., Chambers, J. C., Spector, T. D., Laakso, M., Strom, T. M., Bell, G. I., Blangero, J., Duggirala, R., Tai, E. S., McVean, G., Hanis, C. L., Wilson, J. G., Seielstad, M., Frayling, T. M., Meigs, J. B., Cox, N. J., Sladek, R., Lander, E. S., Gabriel, S., Mohlke, K. L., Meitinger, T., Groop, L., Abecasis, G., Scott, L. J., Morris, A. P., Kang, H. M., Altshuler, D., Burtt, N. P., Florez, J. C., Boehnke, M. & McCarthy, M. I., Jan 23 2018, In : Scientific Data. 5, 1 p.

Research output: Contribution to journalComment/debate

Family history and obesity in youth, their effect on acylcarnitine/aminoacids metabolomics and non-alcoholic fatty liver disease (NAFLD). Structural equation modeling approach

Romero-Ibarguengoitia, M. E., Vadillo-Ortega, F., Caballero, A. E., Ibarra-González, I., Herrera-Rosas, A., Serratos-Canales, M. F., León-Hernández, M., González-Chávez, A., Mummidi, S., Duggirala, R. & López-Alvarenga, J. C., Feb 2018, In : PloS one. 13, 2, e0193138.

Research output: Contribution to journalArticle

8 Scopus citations

Genetic and environmental (physical fitness and sedentary activity) interaction effects on cardiometabolic risk factors in Mexican American children and adolescents

Arya, R., Farook, V. S., Fowler, S. P., Puppala, S., Chittoor, G., Resendez, R. G., Mummidi, S., Vanamala, J. M., Almasy, L., Curran, J. E., Comuzzie, A. G., Lehman, D. M., Jenkinson, C. P., Lynch, J. L., DeFronzo, R. A., Blangero, J., Hale, D. E., Duggirala, R. & Diego, V. P., Jun 2018, In : Genetic epidemiology. 42, 4, p. 378-393 16 p.

Research output: Contribution to journalArticle

Inferring Identical-by-Descent Sharing of Sample Ancestors Promotes High-Resolution Relative Detection

Ramstetter, M. D., Shenoy, S. A., Dyer, T. D., Lehman, D. M., Curran, J. E., Duggirala, R., Blangero, J., Mezey, J. G. & Williams, A. L., Jul 5 2018, In : American Journal of Human Genetics. 103, 1, p. 30-44 15 p.

Research output: Contribution to journalArticle

8 Scopus citations
2017

A Loss-of-Function Splice Acceptor Variant in IGF2 Is Protective for Type 2 Diabetes

Broad Genomics Platform, T2D-GENES Consortium, SIGMA T2D Genetics Consortium & Diabetes Prevention Program Research Group, Nov 1 2017, In : Diabetes. 66, 11, p. 2903-2914 12 p.

Research output: Contribution to journalArticle

16 Scopus citations

A low-frequency inactivating AKT2 variant enriched in the finnish population is associated with fasting insulin levels and type 2 diabetes risk

Manning, A., Highland, H. M., Gasser, J., Sim, X., Tukiainen, T., Fontanillas, P., Grarup, N., Rivas, M. A., Mahajan, A., Locke, A. E., Cingolani, P., Pers, T. H., Viñuela, A., Brown, A. A., Wu, Y., Flannick, J., Fuchsberger, C., Gamazon, E. R., Gaulton, K. J., Im, H. K. & 243 others, Teslovich, T. M., Blackwell, T. W., Bork-Jensen, J., Burtt, N. P., Chen, Y., Green, T., Hartl, C., Kang, H. M., Kumar, A., Ladenvall, C., Ma, C., Moutsianas, L., Pearson, R. D., Perry, J. R. B., Rayner, N. W., Robertson, N. R., Scott, L. J., van de Bunt, M., Eriksson, J. G., Jula, A., Koskinen, S., Lehtimäki, T., Palotie, A., Raitakari, O. T., Jacobs, S. B. R., Wessel, J., Chu, A. Y., Scott, R. A., Goodarzi, M. O., Blancher, C., Buck, G., Buck, D., Chines, P. S., Gabriel, S., Gjesing, A. P., Groves, C. J., Hollensted, M., Huyghe, J. R., Jackson, A. U., Jun, G., Justesen, J. M., Mangino, M., Murphy, J., Neville, M., Onofrio, R., Small, K. S., Stringham, H. M., Trakalo, J., Banks, E., Carey, J., Carneiro, M. O., Depristo, M., Farjoun, Y., Fennell, T., Goldstein, J. I., Grant, G., de Angelis, M. H., Maguire, J., Neale, B. M., Poplin, R., Purcell, S., Schwarzmayr, T., Shakir, K., Smith, J. D., Strom, T. M., Wieland, T., Lindstrom, J., Brandslund, I., Christensen, C., Surdulescu, G. L., Lakka, T. A., Doney, A. S. F., Nilsson, P., Wareham, N. J., Langenberg, C., Varga, T. V., Franks, P. W., Rolandsson, O., Rosengren, A. H., Farook, V. S., Thameem, F., Puppala, S., Kumar, S., Lehman, D. M., Jenkinson, C. P., Curran, J. E., Hale, D. E., Fowler, S. P., Arya, R., Defronzo, R. A., Abboud, H. E., Syvänen, A. C., Hicks, P. J., Palmer, N. D., Ng, M. C. Y., Bowden, D. W., Freedman, B. I., Esko, T., Mägi, R., Milani, L., Mihailov, E., Metspalu, A., Narisu, N., Kinnunen, L., Bonnycastle, L. L., Swift, A., Pasko, D., Wood, A. R., Fadista, J., Pollin, T. I., Barzilai, N., Atzmon, G., Glaser, B., Thorand, B., Strauch, K., Peters, A., Roden, M., Müller-Nurasyid, M., Liang, L., Kriebel, J., Illig, T., Grallert, H., Gieger, C., Meisinger, C., Lannfelt, L., Musani, S. K., Griswold, M., Taylor, H. A., Wilson, G., Correa, A., Oksa, H., Scott, W. R., Afzal, U., Tan, S. T., Loh, M., Chambers, J. C., Sehmi, J., Kooner, J. S., Lehne, B., Cho, Y. S., Lee, J. Y., Han, B. G., Käräjämäki, A., Qi, Q., Qi, L., Huang, J., Hu, F. B., E Mel Ander, O. L., Orho-Melander, M., Below, J. E., Aguilar, D., Wong, T. Y., U, J. L., Khor, C. C., Chia, K. S., Lim, W. Y., Cheng, C. Y., Chan, E., Shyong Tai, E., Aung, T., Linneberg, A., Isomaa, B., Meitinger, T., Tuomi, T., Hakaste, L., Na Kravi C, J., Jørgensen, M. E., Lauritzen, T., Deloukas, P., Stirrups, K. E., Kat, K. H., Farmer, A. J., Frayling, T. M., O’rahilly, S. P., Walker, M., Levy, J. C., Hodgkiss, D., Hattersley, A. T., Kuulasmaa, T., Stan?cáková, A., Barroso, I., Bharadwaj, D., Chan, J., Chandak, G. R., Daly, M. J., Donnelly, P. J., Ebrahim, S. B., Elliott, P., Fingerlin, T., Froguel, P., Hu, C., Jia, W., Ma, R. C. W., McVean, G., Park, T., Prabhakaran, D., Sandhu, M., Scott, J., Sladek, R., Tandon, N., Teo, Y. Y., Zeggini, E., Watanabe, R. M., Koistinen, H. A., Antero Kesaniemi, Y., Uusitupa, M., Spector, T. D., Salomaa, V., Rauramaa, R., Palmer, C. N. A., Prokopenko, I., Morris, A. D., Bergman, R. N., Collins, F. S., Lind, L., Ingelsson, E., Tuomilehto, J., Karpe, F., Groop, L., Jørgensen, T., Hansen, T., Pedersen, O., Kuusisto, J., Abecasis, G., Bell, G. I., Blangero, J., Cox, N. J., Duggirala, R., Seielstad, M., Wilson, J. G., Dupuis, J., Ripatti, S., Hanis, C. L., Florez, J. C., Mohlke, K. L., Meigs, J. B., Laakso, M., Morris, A. P., Boehnke, M., Altshuler, D., McCarthy, M. I., Gloyn, A. L. & Lindgren, C. M., Jul 1 2017, In : Diabetes. 66, 7, p. 2019-2032 14 p.

Research output: Contribution to journalArticle

Open Access
22 Scopus citations

Benchmarking relatedness inference methods with genome-wide data from thousands of relatives

Ramstetter, M. D., Dyer, T. D., Lehman, D. M., Curran, J. E., Duggirala, R., Blangero, J., Mezey, J. G. & Williams, A. L., Jan 1 2017, In : Genetics. 207, 1, p. 75-82 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Data Descriptor: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

Flannick, J., Fuchsberger, C., Mahajan, A., Teslovich, T. M., Agarwala, V., Gaulton, K. J., Caulkins, L., Koesterer, R., Ma, C., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Tajes, J. F. & 281 others, Highland, H. M., Dupuis, J., Chines, P. S., Lindgren, C. M., Hartl, C., Jackson, A. U., Chen, H., Huyghe, J. R., Van De Bunt, M., Pearson, R. D., Kumar, A., Müller-Nurasyid, M., Grarup, N., Stringham, H. M., Gamazon, E. R., Lee, J., Chen, Y., Scott, R. A., Below, J. E., Chen, P., Huang, J., Go, M. J., Stitzel, M. L., Pasko, D., Parker, S. C. J., Varga, T. V., Green, T., Beer, N. L., Day-Williams, A. G., Ferreira, T., Fingerlin, T., Horikoshi, M., Hu, C., Huh, I., Ikram, M. K., Kim, B. J., Kim, Y., Kim, Y. J., Kwon, M. S., Lee, J., Lee, S., Lin, K. H., Maxwell, T. J., Nagai, Y., Wang, X., Welch, R. P., Yoon, J., Zhang, W., Barzilai, N., Voight, B. F., Han, B. G., Jenkinson, C. P., Kuulasmaa, T., Kuusisto, J., Manning, A., Ng, M. C. Y., Palmer, N. D., Balkau, B., Stančáková, A., Abboud, H. E., Boeing, H., Giedraitis, V., Prabhakaran, D., Gottesman, O., Scott, J., Carey, J., Kwan, P., Grant, G., Smith, J. D., Neale, B. M., Purcell, S., Butterworth, A. S., Howson, J. M. M., Lee, H. M., Lu, Y., Kwak, S. H., Zhao, W., Danesh, J., Lam, V. K. L., Park, K. S., Saleheen, D., So, W. Y., Tam, C. H. T., Afzal, U., Aguilar, D., Arya, R., Aung, T., Chan, E., Navarro, C., Cheng, C. Y., Palli, D., Correa, A., Curran, J. E., Rybin, D., Farook, V. S., Fowler, S. P., Freedman, B. I., Griswold, M., Hale, D. E., Hicks, P. J., Khor, C. C., Kumar, S., Lehne, B., Thuillier, D., Lim, W. Y., Liu, J., Loh, M., Musani, S. K., Puppala, S., Scott, W. R., Yengo, L., Tan, S. T., Taylor, H. A., Thameem, F., Wilson, G., Wong, T. Y., Njølstad, P. R., Levy, J. C., Mangino, M., Bonnycastle, L. L., Schwarzmayr, T., Fadista, J., Surdulescu, G. L., Herder, C., Groves, C. J., Wieland, T., Bork-Jensen, J., Brandslund, I., Christensen, C., Koistinen, H. A., Doney, A. S. F., Kinnunen, L., Esko, T., Farmer, A. J., Hakaste, L., Hodgkiss, D., Kravic, J., Lyssenko, V., Hollensted, M., Jørgensen, M. E., Jørgensen, T., Ladenvall, C., Justesen, J. M., Käräjämäki, A., Kriebel, J., Rathmann, W., Lannfelt, L., Lauritzen, T., Narisu, N., Linneberg, A., Melander, O., Milani, L., Neville, M., Orho-Melander, M., Qi, L., Qi, Q., Roden, M., Rolandsson, O., Swift, A., Rosengren, A. H., Stirrups, K., Wood, A. R., Mihailov, E., Blancher, C., Carneiro, M. O., Maguire, J., Poplin, R., Shakir, K., Fennell, T., DePristo, M., De Angelis, M. H., Deloukas, P., Gjesing, A. P., Jun, G., Nilsson, P. M., Murphy, J., Onofrio, R., Thorand, B., Hansen, T., Meisinger, C., Hu, F. B., Isomaa, B., Karpe, F., Liang, L., Peters, A., Huth, C., O'Rahilly, S. P., Palmer, C. N. A., Pedersen, O., Rauramaa, R., Tuomilehto, J., Salomaa, V., Watanabe, R. M., Syvänen, A. C., Bergman, R. N., Bharadwaj, D., Bottinger, E. P., Cho, Y. S., Chandak, G. R., Chan, J. C. N., Chia, K. S., Daly, M. J., Ebrahim, S. B., Langenberg, C., Elliott, P., Jablonski, K. A., Lehman, D. M., Jia, W., Ma, R. C. W., Pollin, T. I., Sandhu, M., Tandon, N., Froguel, P., Barroso, I., Teo, Y. Y., Zeggini, E., Loos, R. J. F., Small, K. S., Ried, J. S., DeFronzo, R. A., Grallert, H., Glaser, B., Metspalu, A., Wareham, N. J., Walker, M., Banks, E., Gieger, C., Ingelsson, E., Im, H. K., Illig, T., Franks, P. W., Buck, G., Trakalo, J., Buck, D., Prokopenko, I., Mägi, R., Lind, L., Farjoun, Y., Owen, K. R., Gloyn, A. L., Strauch, K., Tuomi, T., Kooner, J. S., Lee, J. Y., Park, T., Donnelly, P., Morris, A. D., Hattersley, A. T., Bowden, D. W., Collins, F. S., Atzmon, G., Chambers, J. C., Spector, T. D., Laakso, M., Strom, T. M., Bell, G. I., Blangero, J., Duggirala, R., Tai, E., McVean, G., Hanis, C. L., Wilson, J. G., Seielstad, M., Frayling, T. M., Meigs, J. B., Cox, N. J., Sladek, R., Lander, E. S., Gabriel, S., Mohlke, K. L., Meitinger, T., Groop, L., Abecasis, G., Scott, L. J., Morris, A. P., Kang, H. M., Altshuler, D., Burtt, N. P., Florez, J. C., Boehnke, M. & McCarthy, M. I., Dec 19 2017, In : Scientific Data. 4, 170179.

Research output: Contribution to journalArticle

8 Scopus citations

Effects of conjugated linoleic acid and metformin on insulin sensitivity in obese children: Randomized clinical trial

Garibay-Nieto, N., Queipo-García, G., Alvarez, F., Bustos, M., Villanueva, E., Ramírez, F., León, M., Laresgoiti-Servitje, E., Duggirala, R., Macías, T., Cuevas, S., Jalife, A., Fonseca-Sánchez, M., Serratos, F. & López-Alvarenga, J. C., Jan 1 2017, In : Journal of Clinical Endocrinology and Metabolism. 102, 1, p. 132-140 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Epigenetic age acceleration assessed with human white-matter images

Hodgson, K., Carless, M. A., Kulkarni, H., Curran, J. E., Sprooten, E., Knowles, E. E., Mathias, S., Göring, H. H. H., Yao, N., Olvera, R. L., Fox, P. T., Almasy, L., Duggirala, R., Blangero, J. & Glahn, D. C., May 3 2017, In : Journal of Neuroscience. 37, 18, p. 4735-4743 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees

Jun, G., Manning, A., Almeida, M., Zawistowski, M., Wood, A. R., Teslovich, T. M., Fuchsberger, C., Feng, S., Cingolani, P., Gaulton, K. J., Dyer, T., Blackwell, T. W., Chen, H., Chines, P. S., Choi, S., Churchhouse, C., Fontanillas, P., King, R., Lee, S. Y., Lincoln, S. E. & 54 others, Trubetskoy, V., DePristo, M., Fingerlin, T., Grossman, R., Grundstad, J., Heath, A., Kim, J., Kim, Y. J., Laramie, J., Lee, J., Li, H., Liu, X., Livne, O., Locke, A. E., Maller, J., Mazur, A., Morris, A. P., Pollin, T. I., Ragona, D., Reich, D., Rivas, M. A., Scott, L. J., Sim, X., Tearle, R. G., Teo, Y. Y., Williams, A. L., Zöllner, S., Curran, J. E., Peralta, J., Akolkar, B., Bell, G. I., Burtt, N. P., Cox, N. J., Florez, J. C., Hanis, C. L., McKeon, C., Mohlke, K. L., Seielstad, M., Wilson, J. G., Atzmon, G., Below, J. E., Dupuis, J., Nicolae, D. L., Lehman, D., Park, T., Won, S., Sladek, R., Altshuler, D., McCarthy, M. I., Duggirala, R., Boehnke, M., Frayling, T. M., Abecasis, G. R. & Blangero, J., Jan 9 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 2, p. 379-384 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Genetic correlation of the plasma lipidome with type 2 diabetes, prediabetes and insulin resistance in Mexican American families

Kulkarni, H., Mamtani, M., Wong, G., Weir, J. M., Barlow, C. K., Dyer, T. D., Almasy, L., Mahaney, M. C., Comuzzie, A. G., Duggirala, R., Meikle, P. J., Blangero, J. & Curran, J. E., May 19 2017, In : BMC genetics. 18, 1, 48.

Research output: Contribution to journalArticle

3 Scopus citations

Genetics of serum carotenoid concentrations and their correlation with obesity-related traits in Mexican American children

Farook, V. S., Reddivari, L., Mummidi, S., Puppala, S., Arya, R., Lopez-Alvarenga, J. C., Fowler, S. P., Chittoor, G., Resendez, R. G., Kumar, B. M., Comuzzie, A. G., Curran, J. E., Lehman, D. M., Jenkinson, C. P., Lynch, J. L., DeFronzo, R. A., Blangero, J., Hale, D. E., Duggirala, R. & Vanamala, J. K. P., Jul 1 2017, In : American Journal of Clinical Nutrition. 106, 1, p. 52-58 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Heritability and genetic correlation between GERD symptoms severity, metabolic syndrome, and inflammation markers in families living in Mexico City

Reding-Bernal, A., Sánchez-Pedraza, V., Moreno-Macías, H., Sobrino-Cossio, S., Tejero-Barrera, M. E., Burguete-García, A. I., León-Hernández, M., Serratos-Canales, M. F., Duggirala, R. & López-Alvarenga, J. C., Jun 2017, In : PloS one. 12, 6, e0178815.

Research output: Contribution to journalArticle

6 Scopus citations

Nonalcoholic fatty liver disease can be predicted by retinal vascular changes in patients with obesity without hypertension or diabetes

Romero-Ibarguengoitia, M. E., Herrera-Rosas, A., Domínguez-Mota, A. A., Camas-Benitez, J. T., Serratos-Canales, M. F., León-Hernández, M., González-Chávez, A., López-Ortiz, E., Mummidi, S., Duggirala, R. & López-Alvarenga, J. C., 2017, In : European Journal of Gastroenterology and Hepatology. 29, 8, p. 962-967 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Novel genetic loci associated with hippocampal volume

Hibar, D. P., Adams, H. H. H., Jahanshad, N., Chauhan, G., Stein, J. L., Hofer, E., Renteria, M. E., Bis, J. C., Arias-Vasquez, A., Ikram, M. K., Desrivières, S., Vernooij, M. W., Abramovic, L., Alhusaini, S., Amin, N., Andersson, M., Arfanakis, K., Aribisala, B. S., Armstrong, N. J., Athanasiu, L. & 312 others, Axelsson, T., Beecham, A. H., Beiser, A., Bernard, M., Blanton, S. H., Bohlken, M. M., Boks, M. P., Bralten, J., Brickman, A. M., Carmichael, O., Chakravarty, M. M., Chen, Q., Ching, C. R. K., Chouraki, V., Cuellar-Partida, G., Crivello, F., Den Braber, A., Doan, N. T., Ehrlich, S., Giddaluru, S., Goldman, A. L., Gottesman, R. F., Grimm, O., Griswold, M. E., Guadalupe, T., Gutman, B. A., Hass, J., Haukvik, U. K., Hoehn, D., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Jørgensen, K. N., Karbalai, N., Kasperaviciute, D., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Liewald, D. C. M., Lopez, L. M., Luciano, M., MacAre, C., Marquand, A. F., Matarin, M., Mather, K. A., Mattheisen, M., McKay, D. R., Milaneschi, Y., Muñoz Maniega, S., Nho, K., Nugent, A. C., Nyquist, P., Loohuis, L. M. O., Oosterlaan, J., Papmeyer, M., Pirpamer, L., Pütz, B., Ramasamy, A., Richards, J. S., Risacher, S. L., Roiz-Santiañez, R., Rommelse, N., Ropele, S., Rose, E. J., Royle, N. A., Rundek, T., Sämann, P. G., Saremi, A., Satizabal, C. L., Schmaal, L., Schork, A. J., Shen, L., Shin, J., Shumskaya, E., Smith, A. V., Sprooten, E., Strike, L. T., Teumer, A., Tordesillas-Gutierrez, D., Toro, R., Trabzuni, D., Trompet, S., Vaidya, D., Van Der Grond, J., Van Der Lee, S. J., Van Der Meer, D., Van Donkelaar, M. M. J., Van Eijk, K. R., Van Erp, T. G. M., Van Rooij, D., Walton, E., Westlye, L. T., Whelan, C. D., Windham, B. G., Winkler, A. M., Wittfeld, K., Woldehawariat, G., Wolf, C., Wolfers, T., Yanek, L. R., Yang, J., Zijdenbos, A., Zwiers, M. P., Agartz, I., Almasy, L., Ames, D., Amouyel, P., Andreassen, O. A., Arepalli, S., Assareh, A. A., Barral, S., Bastin, M. E., Becker, D. M., Becker, J. T., Bennett, D. A., Blangero, J., Van Bokhoven, H., Boomsma, D. I., Brodaty, H., Brouwer, R. M., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Bulayeva, K. B., Cahn, W., Calhoun, V. D., Cannon, D. M., Cavalleri, G. L., Cheng, C. Y., Cichon, S., Cookson, M. R., Corvin, A., Crespo-Facorro, B., Curran, J. E., Czisch, M., Dale, A. M., Davies, G. E., De Craen, A. J. M., De Geus, E. J. C., De Jager, P. L., De Zubicaray, G. I., Deary, I. J., Debette, S., Decarli, C., Delanty, N., Depondt, C., Destefano, A., Dillman, A., Djurovic, S., Donohoe, G., Drevets, W. C., Duggirala, R., Dyer, T. D., Enzinger, C., Erk, S., Espeseth, T., Fedko, I. O., Fernández, G., Ferrucci, L., Fisher, S. E., Fleischman, D. A., Ford, I., Fornage, M., Foroud, T. M., Fox, P. T., Francks, C., Fukunaga, M., Gibbs, J. R., Glahn, D. C., Gollub, R. L., Göring, H. H. H., Green, R. C., Gruber, O., Gudnason, V., Guelfi, S., Håberg, A. K., Hansell, N. K., Hardy, J., Hartman, C. A., Hashimoto, R., Hegenscheid, K., Heinz, A., Le Hellard, S., Hernandez, D. G., Heslenfeld, D. J., Ho, B. C., Hoekstra, P. J., Hoffmann, W., Hofman, A., Holsboer, F., Homuth, G., Hosten, N., Hottenga, J. J., Huentelman, M., Pol, H. E. H., Ikeda, M., Jack, C. R., Jenkinson, M., Johnson, R., Jönsson, E. G., Jukema, J. W., Kahn, R. S., Kanai, R., Kloszewska, I., Knopman, D. S., Kochunov, P., Kwok, J. B., Lawrie, S. M., Lemaître, H., Liu, X., Longo, D. L., Lopez, O. L., Lovestone, S., Martinez, O., Martinot, J. L., Mattay, V. S., McDonald, C., McIntosh, A. M., McMahon, F. J., McMahon, K. L., Mecocci, P., Melle, I., Meyer-Lindenberg, A., Mohnke, S., Montgomery, G. W., Morris, D. W., Mosley, T. H., Mühleisen, T. W., Müller-Myhsok, B., Nalls, M. A., Nauck, M., Nichols, T. E., Niessen, W. J., Nöthen, M. M., Nyberg, L., Ohi, K., Olvera, R. L., Ophoff, R. A., Pandolfo, M., Paus, T., Pausova, Z., Penninx, B. W. J. H., Pike, G. B., Potkin, S. G., Psaty, B. M., Reppermund, S., Rietschel, M., Roffman, J. L., Romanczuk-Seiferth, N., Rotter, J. I., Ryten, M., Sacco, R. L., Sachdev, P. S., Saykin, A. J., Schmidt, R., Schmidt, H., Schofield, P. R., Sigursson, S., Simmons, A., Singleton, A., Sisodiya, S. M., Smith, C., Smoller, J. W., Soininen, H., Steen, V. M., Stott, D. J., Sussmann, J. E., Thalamuthu, A., Toga, A. W., Traynor, B. J., Troncoso, J., Tsolaki, M., Tzourio, C., Uitterlinden, A. G., Hernández, M. C. V., Van Der Brug, M., Van Der Lugt, A., Van Der Wee, N. J. A., Van Haren, N. E. M., Van 'T Ent, D., Van Tol, M. J., Vardarajan, B. N., Vellas, B., Veltman, D. J., Völzke, H., Walter, H., Wardlaw, J. M., Wassink, T. H., Weale, M. E., Weinberger, D. R., Weiner, M. W., Wen, W., Westman, E., White, T., Wong, T. Y., Wright, C. B., Zielke, R. H., Zonderman, A. B., Martin, N. G., Van Duijn, C. M., Wright, M. J., Longstreth, W. T., Schumann, G., Grabe, H. J., Franke, B., Launer, L. J., Medland, S. E., Seshadri, S., Thompson, P. M. & Ikram, M. A., Jan 18 2017, In : Nature communications. 8, 13624.

Research output: Contribution to journalArticle

87 Scopus citations

Serum phosphatidylinositol as a biomarker for bipolar disorder liability

Knowles, E. E., Meikle, P. J., Huynh, K., Göring, H. H., Olvera, R. L., Mathias, S. R., Duggirala, R., Almasy, L., Blangero, J., Curran, J. E. & Glahn, D. C., 2017, (Accepted/In press) In : Bipolar Disorders.

Research output: Contribution to journalArticle

6 Scopus citations

Shared Genetic Factors Influence Head Motion During MRI and Body Mass Index

Hodgson, K., Poldrack, R. A., Curran, J. E., Knowles, E. E., Mathias, S., Göring, H. H. H., Yao, N., Olvera, R. L., Fox, P. T., Almasy, L., Duggirala, R., Barch, D. M., Blangero, J. & Glahn, D. C., Dec 1 2017, In : Cerebral cortex (New York, N.Y. : 1991). 27, 12, p. 5539-5546 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

The effect size of type 2 diabetes mellitus on tuberculosis drug resistance and adverse treatment outcomes

Perez-Navarro, L. M., Restrepo, B. I., Fuentes-Dominguez, F. J., Duggirala, R., Morales-Romero, J., López-Alvarenga, J. C., Comas, I. & Zenteno-Cuevas, R., Mar 1 2017, In : Tuberculosis. 103, p. 83-91 9 p.

Research output: Contribution to journalArticle

21 Scopus citations

The genetic basis of the comorbidity between cannabis use and major depression

Hodgson, K., Almasy, L., Knowles, E. E. M., Kent, J. W., Curran, J. E., Dyer, T. D., Göring, H. H. H., Olvera, R. L., Woolsey, M. D., Duggirala, R., Fox, P. T., Blangero, J. & Glahn, D. C., Jan 1 2017, In : Addiction. 112, 1, p. 113-123 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

The lipidome in major depressive disorder: Shared genetic influence for ether-phosphatidylcholines, a plasma-based phenotype related to inflammation, and disease risk

Knowles, E. E. M., Huynh, K., Meikle, P. J., Göring, H. H. H., Olvera, R. L., Mathias, S. R., Duggirala, R., Almasy, L., Blangero, J., Curran, J. E. & Glahn, D. C., Jun 1 2017, In : European Psychiatry. 43, p. 44-50 7 p.

Research output: Contribution to journalArticle

9 Scopus citations
2016

Analysis of protein-coding genetic variation in 60,706 humans

Lek, M., Karczewski, K. J., Minikel, E. V., Samocha, K. E., Banks, E., Fennell, T., O'Donnell-Luria, A. H., Ware, J. S., Hill, A. J., Cummings, B. B., Tukiainen, T., Birnbaum, D. P., Kosmicki, J. A., Duncan, L. E., Estrada, K., Zhao, F., Zou, J., Pierce-Hoffman, E., Berghout, J., Cooper, D. N. & 153 others, Deflaux, N., DePristo, M., Do, R., Flannick, J., Fromer, M., Gauthier, L., Goldstein, J., Gupta, N., Howrigan, D., Kiezun, A., Kurki, M. I., Moonshine, A. L., Natarajan, P., Orozco, L., Peloso, G. M., Poplin, R., Rivas, M. A., Ruano-Rubio, V., Rose, S. A., Ruderfer, D. M., Shakir, K., Stenson, P. D., Stevens, C., Thomas, B. P., Tiao, G., Tusie-Luna, M. T., Weisburd, B., Won, H. H., Yu, D., Altshuler, D. M., Ardissino, D., Boehnke, M., Danesh, J., Donnelly, S., Elosua, R., Florez, J. C., Gabriel, S. B., Getz, G., Glatt, S. J., Hultman, C. M., Kathiresan, S., Laakso, M., McCarroll, S., McCarthy, M. I., McGovern, D., McPherson, R., Neale, B. M., Palotie, A., Purcell, S. M., Saleheen, D., Scharf, J. M., Sklar, P., Sullivan, P. F., Tuomilehto, J., Tsuang, M. T., Watkins, H. C., Wilson, J. G., Daly, M. J., MacArthur, D. G., Abboud, H. E., Abecasis, G., Aguilar-Salinas, C. A., Arellano-Campos, O., Atzmon, G., Aukrust, I., Barr, C. L., Bell, G. I., Bergen, S., Bjørkhaug, L., Blangero, J., Bowden, D. W., Budman, C. L., Burtt, N. P., Centeno-Cruz, F., Chambers, J. C., Chambert, K., Clarke, R., Collins, R., Coppola, G., Córdova, E. J., Cortes, M. L., Cox, N. J., Duggirala, R., Farrall, M., Fernandez-Lopez, J. C., Fontanillas, P., Frayling, T. M., Freimer, N. B., Fuchsberger, C., García-Ortiz, H., Goel, A., Gómez-Vázquez, M. J., González-Villalpando, M. E., González-Villalpando, C., Grados, M. A., Groop, L., Haiman, C. A., Hanis, C. L., Hattersley, A. T., Henderson, B. E., Hopewell, J. C., Huerta-Chagoya, A., Islas-Andrade, S., Jacobs, S. B., Jalilzadeh, S., Jenkinson, C. P., Moran, J., Jiménez-Morale, S., Kähler, A., King, R. A., Kirov, G., Kooner, J. S., Kyriakou, T., Lee, J. Y., Lehman, D. M., Lyon, G., MacMahon, W., Magnusson, P. K., Mahajan, A., Marrugat, J., Martínez-Hernández, A., Mathews, C. A., McVean, G., Meigs, J. B., Meitinger, T., Mendoza-Caamal, E., Mercader, J. M., Mohlke, K. L., Moreno-Macías, H., Morris, A. P., Najmi, L. A., Njølstad, P. R., O'Donovan, M. C., Ordóñez-Sánchez, M. L., Owen, M. J., Park, T., Pauls, D. L., Posthuma, D., Revilla-Monsalve, C., Riba, L., Ripke, S., Rodríguez-Guillén, R., Rodríguez-Torres, M., Sandor, P., Seielstad, M., Sladek, R., Soberón, X., Spector, T. D., Tai, S. E., Teslovich, T. M., Walford, G., Wilkens, L. R. & Williams, A. L., Aug 17 2016, In : Nature. 536, 7616, p. 285-291 7 p.

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Open Access
4577 Scopus citations

Exome sequence data from multigenerational families implicate AMPA receptor trafficking in neurocognitive impairment and schizophrenia risk

Kos, M. Z., Carless, M. A., Peralta, J., Blackburn, A., Almeida, M., Roalf, D., Pogue-Geile, M. F., Prasad, K., Gur, R. C., Nimgaonkar, V., Curran, J. E., Duggirala, R., Glahn, D. C., Blangero, J., Gur, R. E. & Almasy, L., 2016, In : Schizophrenia bulletin. 42, 2, p. 288-300 13 p.

Research output: Contribution to journalArticle

9 Scopus citations