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  • Hanna E Abboud
2020

Interplay between RNA-binding protein HuR and Nox4 as a novel therapeutic target in diabetic kidney disease

Shi, Q., Lee, D. Y., Féliers, D., Abboud, H. E., Bhat, M. A. & Gorin, Y., Jun 2020, In : Molecular Metabolism. 36, 100968.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2019

JC viruria is associated with reduced risk of diabetic kidney disease

Family Investigation of Nephropathy and Diabetes (FIND Consortium), Jun 1 2019, In : Journal of Clinical Endocrinology and Metabolism. 104, 6, p. 2286-2294 9 p.

Research output: Contribution to journalArticle

1 Scopus citations
2018

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

Flannick, J., Fuchsberger, C., Mahajan, A., Teslovich, T. M., Agarwala, V., Gaulton, K. J., Caulkins, L., Koesterer, R., Ma, C., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Tajes, J. F. & 281 others, Highland, H. M., Dupuis, J., Chines, P. S., Lindgren, C. M., Hartl, C., Jackson, A. U., Chen, H., Huyghe, J. R., van de Bunt, M., Pearson, R. D., Kumar, A., Müller-Nurasyid, M., Grarup, N., Stringham, H. M., Gamazon, E. R., Lee, J., Chen, Y., Scott, R. A., Below, J. E., Chen, P., Huang, J., Go, M. J., Stitzel, M. L., Pasko, D., Parker, S. C. J., Varga, T. V., Green, T., Beer, N. L., Day-Williams, A. G., Ferreira, T., Fingerlin, T., Horikoshi, M., Hu, C., Huh, I., Ikram, M. K., Kim, B. J., Kim, Y., Kim, Y. J., Kwon, M. S., Lee, J., Lee, S., Lin, K. H., Maxwell, T. J., Nagai, Y., Wang, X., Welch, R. P., Yoon, J., Zhang, W., Barzilai, N., Voight, B. F., Han, B. G., Jenkinson, C. P., Kuulasmaa, T., Kuusisto, J., Manning, A., Ng, M. C. Y., Palmer, N. D., Balkau, B., Stančáková, A., Abboud, H. E., Boeing, H., Giedraitis, V., Prabhakaran, D., Gottesman, O., Scott, J., Carey, J., Kwan, P., Grant, G., Smith, J. D., Neale, B. M., Purcell, S., Butterworth, A. S., Howson, J. M. M., Lee, H. M., Lu, Y., Kwak, S. H., Zhao, W., Danesh, J., Lam, V. K. L., Park, K. S., Saleheen, D., So, W. Y., Tam, C. H. T., Afzal, U., Aguilar, D., Arya, R., Aung, T., Chan, E., Navarro, C., Cheng, C. Y., Palli, D., Correa, A., Curran, J. E., Rybin, D., Farook, V. S., Fowler, S. P., Freedman, B. I., Griswold, M., Hale, D. E., Hicks, P. J., Khor, C. C., Kumar, S., Lehne, B., Thuillier, D., Lim, W. Y., Liu, J., Loh, M., Musani, S. K., Puppala, S., Scott, W. R., Yengo, L., Tan, S. T., Taylor, H. A., Thameem, F., Wilson, G., Wong, T. Y., Njølstad, P. R., Levy, J. C., Mangino, M., Bonnycastle, L. L., Schwarzmayr, T., Fadista, J., Surdulescu, G. L., Herder, C., Groves, C. J., Wieland, T., Bork-Jensen, J., Brandslund, I., Christensen, C., Koistinen, H. A., Doney, A. S. F., Kinnunen, L., Esko, T., Farmer, A. J., Hakaste, L., Hodgkiss, D., Kravic, J., Lyssenko, V., Hollensted, M., Jørgensen, M. E., Jørgensen, T., Ladenvall, C., Justesen, J. M., Käräjämäki, A., Kriebel, J., Rathmann, W., Lannfelt, L., Lauritzen, T., Narisu, N., Linneberg, A., Melander, O., Milani, L., Neville, M., Orho-Melander, M., Qi, L., Qi, Q., Roden, M., Rolandsson, O., Swift, A., Rosengren, A. H., Stirrups, K., Wood, A. R., Mihailov, E., Blancher, C., Carneiro, M. O., Maguire, J., Poplin, R., Shakir, K., Fennell, T., DePristo, M., de Angelis, M. H., Deloukas, P., Gjesing, A. P., Jun, G., Nilsson, P., Murphy, J., Onofrio, R., Thorand, B., Hansen, T., Meisinger, C., Hu, F. B., Isomaa, B., Karpe, F., Liang, L., Peters, A., Huth, C., O'Rahilly, S. P., Palmer, C. N. A., Pedersen, O., Rauramaa, R., Tuomilehto, J., Salomaa, V., Watanabe, R. M., Syvänen, A. C., Bergman, R. N., Bharadwaj, D., Bottinger, E. P., Cho, Y. S., Chandak, G. R., Chan, J. C. N., Chia, K. S., Daly, M. J., Ebrahim, S. B., Langenberg, C., Elliott, P., Jablonski, K. A., Lehman, D. M., Jia, W., Ma, R. C. W., Pollin, T. I., Sandhu, M., Tandon, N., Froguel, P., Barroso, I., Teo, Y. Y., Zeggini, E., Loos, R. J. F., Small, K. S., Ried, J. S., DeFronzo, R. A., Grallert, H., Glaser, B., Metspalu, A., Wareham, N. J., Walker, M., Banks, E., Gieger, C., Ingelsson, E., Im, H. K., Illig, T., Franks, P. W., Buck, G., Trakalo, J., Buck, D., Prokopenko, I., Mägi, R., Lind, L., Farjoun, Y., Owen, K. R., Gloyn, A. L., Strauch, K., Tuomi, T., Kooner, J. S., Lee, J. Y., Park, T., Donnelly, P., Morris, A. D., Hattersley, A. T., Bowden, D. W., Collins, F. S., Atzmon, G., Chambers, J. C., Spector, T. D., Laakso, M., Strom, T. M., Bell, G. I., Blangero, J., Duggirala, R., Tai, E. S., McVean, G., Hanis, C. L., Wilson, J. G., Seielstad, M., Frayling, T. M., Meigs, J. B., Cox, N. J., Sladek, R., Lander, E. S., Gabriel, S., Mohlke, K. L., Meitinger, T., Groop, L., Abecasis, G., Scott, L. J., Morris, A. P., Kang, H. M., Altshuler, D., Burtt, N. P., Florez, J. C., Boehnke, M. & McCarthy, M. I., Jan 23 2018, In : Scientific Data. 5, 1 p.

Research output: Contribution to journalComment/debate

Mouse Metanephric Mesenchymal Cell–Derived Angioblasts Undergo Vasculogenesis in Three-Dimensional Culture

Patel, M., Velagapudi, C., Burns, H., Doss, R., Lee, M. J., Mariappan, M. M., Wagner, B., Arar, M., Barnes, V. L., Abboud, H. E. & Barnes, J. L., Mar 1 2018, In : American Journal of Pathology. 188, 3, p. 768-784 17 p.

Research output: Contribution to journalArticle

Nox4 is a Target for Tuberin Deficiency Syndrome

Shi, Q., Viswanadhapalli, S., Friedrichs, W. E., Velagapudi, C., Szyndralewiez, C., Bansal, S., Bhat, M. A., Choudhury, G. G. & Abboud, H. E., Dec 1 2018, In : Scientific reports. 8, 1, 3781.

Research output: Contribution to journalArticle

2 Scopus citations
2017

A Loss-of-Function Splice Acceptor Variant in IGF2 Is Protective for Type 2 Diabetes

Broad Genomics Platform, T2D-GENES Consortium, SIGMA T2D Genetics Consortium & Diabetes Prevention Program Research Group, Nov 1 2017, In : Diabetes. 66, 11, p. 2903-2914 12 p.

Research output: Contribution to journalArticle

16 Scopus citations

A low-frequency inactivating AKT2 variant enriched in the finnish population is associated with fasting insulin levels and type 2 diabetes risk

Manning, A., Highland, H. M., Gasser, J., Sim, X., Tukiainen, T., Fontanillas, P., Grarup, N., Rivas, M. A., Mahajan, A., Locke, A. E., Cingolani, P., Pers, T. H., Viñuela, A., Brown, A. A., Wu, Y., Flannick, J., Fuchsberger, C., Gamazon, E. R., Gaulton, K. J., Im, H. K. & 243 others, Teslovich, T. M., Blackwell, T. W., Bork-Jensen, J., Burtt, N. P., Chen, Y., Green, T., Hartl, C., Kang, H. M., Kumar, A., Ladenvall, C., Ma, C., Moutsianas, L., Pearson, R. D., Perry, J. R. B., Rayner, N. W., Robertson, N. R., Scott, L. J., van de Bunt, M., Eriksson, J. G., Jula, A., Koskinen, S., Lehtimäki, T., Palotie, A., Raitakari, O. T., Jacobs, S. B. R., Wessel, J., Chu, A. Y., Scott, R. A., Goodarzi, M. O., Blancher, C., Buck, G., Buck, D., Chines, P. S., Gabriel, S., Gjesing, A. P., Groves, C. J., Hollensted, M., Huyghe, J. R., Jackson, A. U., Jun, G., Justesen, J. M., Mangino, M., Murphy, J., Neville, M., Onofrio, R., Small, K. S., Stringham, H. M., Trakalo, J., Banks, E., Carey, J., Carneiro, M. O., Depristo, M., Farjoun, Y., Fennell, T., Goldstein, J. I., Grant, G., de Angelis, M. H., Maguire, J., Neale, B. M., Poplin, R., Purcell, S., Schwarzmayr, T., Shakir, K., Smith, J. D., Strom, T. M., Wieland, T., Lindstrom, J., Brandslund, I., Christensen, C., Surdulescu, G. L., Lakka, T. A., Doney, A. S. F., Nilsson, P., Wareham, N. J., Langenberg, C., Varga, T. V., Franks, P. W., Rolandsson, O., Rosengren, A. H., Farook, V. S., Thameem, F., Puppala, S., Kumar, S., Lehman, D. M., Jenkinson, C. P., Curran, J. E., Hale, D. E., Fowler, S. P., Arya, R., Defronzo, R. A., Abboud, H. E., Syvänen, A. C., Hicks, P. J., Palmer, N. D., Ng, M. C. Y., Bowden, D. W., Freedman, B. I., Esko, T., Mägi, R., Milani, L., Mihailov, E., Metspalu, A., Narisu, N., Kinnunen, L., Bonnycastle, L. L., Swift, A., Pasko, D., Wood, A. R., Fadista, J., Pollin, T. I., Barzilai, N., Atzmon, G., Glaser, B., Thorand, B., Strauch, K., Peters, A., Roden, M., Müller-Nurasyid, M., Liang, L., Kriebel, J., Illig, T., Grallert, H., Gieger, C., Meisinger, C., Lannfelt, L., Musani, S. K., Griswold, M., Taylor, H. A., Wilson, G., Correa, A., Oksa, H., Scott, W. R., Afzal, U., Tan, S. T., Loh, M., Chambers, J. C., Sehmi, J., Kooner, J. S., Lehne, B., Cho, Y. S., Lee, J. Y., Han, B. G., Käräjämäki, A., Qi, Q., Qi, L., Huang, J., Hu, F. B., E Mel Ander, O. L., Orho-Melander, M., Below, J. E., Aguilar, D., Wong, T. Y., U, J. L., Khor, C. C., Chia, K. S., Lim, W. Y., Cheng, C. Y., Chan, E., Shyong Tai, E., Aung, T., Linneberg, A., Isomaa, B., Meitinger, T., Tuomi, T., Hakaste, L., Na Kravi C, J., Jørgensen, M. E., Lauritzen, T., Deloukas, P., Stirrups, K. E., Kat, K. H., Farmer, A. J., Frayling, T. M., O’rahilly, S. P., Walker, M., Levy, J. C., Hodgkiss, D., Hattersley, A. T., Kuulasmaa, T., Stan?cáková, A., Barroso, I., Bharadwaj, D., Chan, J., Chandak, G. R., Daly, M. J., Donnelly, P. J., Ebrahim, S. B., Elliott, P., Fingerlin, T., Froguel, P., Hu, C., Jia, W., Ma, R. C. W., McVean, G., Park, T., Prabhakaran, D., Sandhu, M., Scott, J., Sladek, R., Tandon, N., Teo, Y. Y., Zeggini, E., Watanabe, R. M., Koistinen, H. A., Antero Kesaniemi, Y., Uusitupa, M., Spector, T. D., Salomaa, V., Rauramaa, R., Palmer, C. N. A., Prokopenko, I., Morris, A. D., Bergman, R. N., Collins, F. S., Lind, L., Ingelsson, E., Tuomilehto, J., Karpe, F., Groop, L., Jørgensen, T., Hansen, T., Pedersen, O., Kuusisto, J., Abecasis, G., Bell, G. I., Blangero, J., Cox, N. J., Duggirala, R., Seielstad, M., Wilson, J. G., Dupuis, J., Ripatti, S., Hanis, C. L., Florez, J. C., Mohlke, K. L., Meigs, J. B., Laakso, M., Morris, A. P., Boehnke, M., Altshuler, D., McCarthy, M. I., Gloyn, A. L. & Lindgren, C. M., Jul 1 2017, In : Diabetes. 66, 7, p. 2019-2032 14 p.

Research output: Contribution to journalArticle

Open Access
22 Scopus citations

Data Descriptor: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

Flannick, J., Fuchsberger, C., Mahajan, A., Teslovich, T. M., Agarwala, V., Gaulton, K. J., Caulkins, L., Koesterer, R., Ma, C., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Tajes, J. F. & 281 others, Highland, H. M., Dupuis, J., Chines, P. S., Lindgren, C. M., Hartl, C., Jackson, A. U., Chen, H., Huyghe, J. R., Van De Bunt, M., Pearson, R. D., Kumar, A., Müller-Nurasyid, M., Grarup, N., Stringham, H. M., Gamazon, E. R., Lee, J., Chen, Y., Scott, R. A., Below, J. E., Chen, P., Huang, J., Go, M. J., Stitzel, M. L., Pasko, D., Parker, S. C. J., Varga, T. V., Green, T., Beer, N. L., Day-Williams, A. G., Ferreira, T., Fingerlin, T., Horikoshi, M., Hu, C., Huh, I., Ikram, M. K., Kim, B. J., Kim, Y., Kim, Y. J., Kwon, M. S., Lee, J., Lee, S., Lin, K. H., Maxwell, T. J., Nagai, Y., Wang, X., Welch, R. P., Yoon, J., Zhang, W., Barzilai, N., Voight, B. F., Han, B. G., Jenkinson, C. P., Kuulasmaa, T., Kuusisto, J., Manning, A., Ng, M. C. Y., Palmer, N. D., Balkau, B., Stančáková, A., Abboud, H. E., Boeing, H., Giedraitis, V., Prabhakaran, D., Gottesman, O., Scott, J., Carey, J., Kwan, P., Grant, G., Smith, J. D., Neale, B. M., Purcell, S., Butterworth, A. S., Howson, J. M. M., Lee, H. M., Lu, Y., Kwak, S. H., Zhao, W., Danesh, J., Lam, V. K. L., Park, K. S., Saleheen, D., So, W. Y., Tam, C. H. T., Afzal, U., Aguilar, D., Arya, R., Aung, T., Chan, E., Navarro, C., Cheng, C. Y., Palli, D., Correa, A., Curran, J. E., Rybin, D., Farook, V. S., Fowler, S. P., Freedman, B. I., Griswold, M., Hale, D. E., Hicks, P. J., Khor, C. C., Kumar, S., Lehne, B., Thuillier, D., Lim, W. Y., Liu, J., Loh, M., Musani, S. K., Puppala, S., Scott, W. R., Yengo, L., Tan, S. T., Taylor, H. A., Thameem, F., Wilson, G., Wong, T. Y., Njølstad, P. R., Levy, J. C., Mangino, M., Bonnycastle, L. L., Schwarzmayr, T., Fadista, J., Surdulescu, G. L., Herder, C., Groves, C. J., Wieland, T., Bork-Jensen, J., Brandslund, I., Christensen, C., Koistinen, H. A., Doney, A. S. F., Kinnunen, L., Esko, T., Farmer, A. J., Hakaste, L., Hodgkiss, D., Kravic, J., Lyssenko, V., Hollensted, M., Jørgensen, M. E., Jørgensen, T., Ladenvall, C., Justesen, J. M., Käräjämäki, A., Kriebel, J., Rathmann, W., Lannfelt, L., Lauritzen, T., Narisu, N., Linneberg, A., Melander, O., Milani, L., Neville, M., Orho-Melander, M., Qi, L., Qi, Q., Roden, M., Rolandsson, O., Swift, A., Rosengren, A. H., Stirrups, K., Wood, A. R., Mihailov, E., Blancher, C., Carneiro, M. O., Maguire, J., Poplin, R., Shakir, K., Fennell, T., DePristo, M., De Angelis, M. H., Deloukas, P., Gjesing, A. P., Jun, G., Nilsson, P. M., Murphy, J., Onofrio, R., Thorand, B., Hansen, T., Meisinger, C., Hu, F. B., Isomaa, B., Karpe, F., Liang, L., Peters, A., Huth, C., O'Rahilly, S. P., Palmer, C. N. A., Pedersen, O., Rauramaa, R., Tuomilehto, J., Salomaa, V., Watanabe, R. M., Syvänen, A. C., Bergman, R. N., Bharadwaj, D., Bottinger, E. P., Cho, Y. S., Chandak, G. R., Chan, J. C. N., Chia, K. S., Daly, M. J., Ebrahim, S. B., Langenberg, C., Elliott, P., Jablonski, K. A., Lehman, D. M., Jia, W., Ma, R. C. W., Pollin, T. I., Sandhu, M., Tandon, N., Froguel, P., Barroso, I., Teo, Y. Y., Zeggini, E., Loos, R. J. F., Small, K. S., Ried, J. S., DeFronzo, R. A., Grallert, H., Glaser, B., Metspalu, A., Wareham, N. J., Walker, M., Banks, E., Gieger, C., Ingelsson, E., Im, H. K., Illig, T., Franks, P. W., Buck, G., Trakalo, J., Buck, D., Prokopenko, I., Mägi, R., Lind, L., Farjoun, Y., Owen, K. R., Gloyn, A. L., Strauch, K., Tuomi, T., Kooner, J. S., Lee, J. Y., Park, T., Donnelly, P., Morris, A. D., Hattersley, A. T., Bowden, D. W., Collins, F. S., Atzmon, G., Chambers, J. C., Spector, T. D., Laakso, M., Strom, T. M., Bell, G. I., Blangero, J., Duggirala, R., Tai, E., McVean, G., Hanis, C. L., Wilson, J. G., Seielstad, M., Frayling, T. M., Meigs, J. B., Cox, N. J., Sladek, R., Lander, E. S., Gabriel, S., Mohlke, K. L., Meitinger, T., Groop, L., Abecasis, G., Scott, L. J., Morris, A. P., Kang, H. M., Altshuler, D., Burtt, N. P., Florez, J. C., Boehnke, M. & McCarthy, M. I., Dec 19 2017, In : Scientific Data. 4, 170179.

Research output: Contribution to journalArticle

8 Scopus citations

Hydrogen sulfide inhibits high glucose-induced NADPH oxidase 4 expression and matrix increase by recruiting inducible nitric oxide synthase in kidney proximal tubular epithelial cells

Lee, H. J., Lee, D. Y., Mariappan, M. M., Feliers, D., Ghosh-choudhury, G., Abboud, H. E., Gorin, Y. & Kasinath, B. S., Apr 7 2017, In : Journal of Biological Chemistry. 292, 14, p. 5665-5675 11 p.

Research output: Contribution to journalArticle

17 Scopus citations

Tryptophan metabolism in patients with chronic kidney disease secondary to type 2 diabetes: Relationship to inflammatory markers

Debnath, S., Velagapudi, C., Redus, L., Thameem, F., Kasinath, B., Hura, C. E., Lorenzo, C., Abboud, H. E. & O'Connor, J. C., Jan 1 2017, In : International Journal of Tryptophan Research. 10, 1

Research output: Contribution to journalArticle

25 Scopus citations
2016

Analysis of protein-coding genetic variation in 60,706 humans

Lek, M., Karczewski, K. J., Minikel, E. V., Samocha, K. E., Banks, E., Fennell, T., O'Donnell-Luria, A. H., Ware, J. S., Hill, A. J., Cummings, B. B., Tukiainen, T., Birnbaum, D. P., Kosmicki, J. A., Duncan, L. E., Estrada, K., Zhao, F., Zou, J., Pierce-Hoffman, E., Berghout, J., Cooper, D. N. & 153 others, Deflaux, N., DePristo, M., Do, R., Flannick, J., Fromer, M., Gauthier, L., Goldstein, J., Gupta, N., Howrigan, D., Kiezun, A., Kurki, M. I., Moonshine, A. L., Natarajan, P., Orozco, L., Peloso, G. M., Poplin, R., Rivas, M. A., Ruano-Rubio, V., Rose, S. A., Ruderfer, D. M., Shakir, K., Stenson, P. D., Stevens, C., Thomas, B. P., Tiao, G., Tusie-Luna, M. T., Weisburd, B., Won, H. H., Yu, D., Altshuler, D. M., Ardissino, D., Boehnke, M., Danesh, J., Donnelly, S., Elosua, R., Florez, J. C., Gabriel, S. B., Getz, G., Glatt, S. J., Hultman, C. M., Kathiresan, S., Laakso, M., McCarroll, S., McCarthy, M. I., McGovern, D., McPherson, R., Neale, B. M., Palotie, A., Purcell, S. M., Saleheen, D., Scharf, J. M., Sklar, P., Sullivan, P. F., Tuomilehto, J., Tsuang, M. T., Watkins, H. C., Wilson, J. G., Daly, M. J., MacArthur, D. G., Abboud, H. E., Abecasis, G., Aguilar-Salinas, C. A., Arellano-Campos, O., Atzmon, G., Aukrust, I., Barr, C. L., Bell, G. I., Bergen, S., Bjørkhaug, L., Blangero, J., Bowden, D. W., Budman, C. L., Burtt, N. P., Centeno-Cruz, F., Chambers, J. C., Chambert, K., Clarke, R., Collins, R., Coppola, G., Córdova, E. J., Cortes, M. L., Cox, N. J., Duggirala, R., Farrall, M., Fernandez-Lopez, J. C., Fontanillas, P., Frayling, T. M., Freimer, N. B., Fuchsberger, C., García-Ortiz, H., Goel, A., Gómez-Vázquez, M. J., González-Villalpando, M. E., González-Villalpando, C., Grados, M. A., Groop, L., Haiman, C. A., Hanis, C. L., Hattersley, A. T., Henderson, B. E., Hopewell, J. C., Huerta-Chagoya, A., Islas-Andrade, S., Jacobs, S. B., Jalilzadeh, S., Jenkinson, C. P., Moran, J., Jiménez-Morale, S., Kähler, A., King, R. A., Kirov, G., Kooner, J. S., Kyriakou, T., Lee, J. Y., Lehman, D. M., Lyon, G., MacMahon, W., Magnusson, P. K., Mahajan, A., Marrugat, J., Martínez-Hernández, A., Mathews, C. A., McVean, G., Meigs, J. B., Meitinger, T., Mendoza-Caamal, E., Mercader, J. M., Mohlke, K. L., Moreno-Macías, H., Morris, A. P., Najmi, L. A., Njølstad, P. R., O'Donovan, M. C., Ordóñez-Sánchez, M. L., Owen, M. J., Park, T., Pauls, D. L., Posthuma, D., Revilla-Monsalve, C., Riba, L., Ripke, S., Rodríguez-Guillén, R., Rodríguez-Torres, M., Sandor, P., Seielstad, M., Sladek, R., Soberón, X., Spector, T. D., Tai, S. E., Teslovich, T. M., Walford, G., Wilkens, L. R. & Williams, A. L., Aug 17 2016, In : Nature. 536, 7616, p. 285-291 7 p.

Research output: Contribution to journalArticle

Open Access
4577 Scopus citations

Genetic Variants in Toll-Like Receptor 4 Gene and Their Association Analysis with Estimated Glomerular Filtration Rate in Mexican American Families

Thameem, F., Puppala, S., Farook, V. S., Kasinath, B. S., Blangero, J., Duggirala, R. & Abboud, H. E., May 20 2016, (Accepted/In press) In : CardioRenal Medicine. p. 301-306 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

MTORC2 Signaling Regulates Nox4-Induced Podocyte Depletion in Diabetes

Eid, S., Boutary, S., Braych, K., Sabra, R., Massaad, C., Hamdy, A., Rashid, A., Moodad, S., Block, K., Gorin, Y., Abboud, H. E. & Eid, A. A., Nov 1 2016, In : Antioxidants and Redox Signaling. 25, 13, p. 703-719 17 p.

Research output: Contribution to journalArticle

27 Scopus citations

Selecting SNPs informative for African, American Indian and European Ancestry: Application to the Family Investigation of Nephropathy and Diabetes (FIND)

Williams, R. C., Elston, R. C., Kumar, P., Knowler, W. C., Abboud, H. E., Adler, S., Bowden, D. W., Divers, J., Freedman, B. I., Igo, R. P., Ipp, E., Iyengar, S. K., Kimmel, P. L., Klag, M. J., Kohn, O., Langefeld, C. D., Leehey, D. J., Nelson, R. G., Nicholas, S. B., Pahl, M. V. & 108 others, Parekh, R. S., Rotter, J. I., Schelling, J. R., Sedor, J. R., Shah, V. O., Smith, M. W., Taylor, K. D., Thameem, F., Thornley-Brown, D., Winkler, C. A., Guo, X., Zager, P., Hanson, R. L., FIND Research Group, R. G., S.K. Iyengar, I., Elston, R. C., Goddard, K. A. B., Olson, J. M., Ialacci, S., Fondran, J., Horvath, A., Igo, R., Jun, G., Kramp, K., Molineros, J., Quade, S. R. E., Schelling, J., Pickens, A., Humbert, L., Getz-Fradley, L., Adler, S., Ipp, E., Pahl, M., Seldin, M. F., Snyder, S., Tayek, J., Hernandez, E., LaPage, J., Garcia, C., Gonzalez, J., Aguilar, M., Parekh, R., Kao, L., Meoni, L., Whitehead, T., Chester, J., Knowler, W. C., Hanson, R. L., Nelson, R. G., Wolford, J., Jones, L., Juan, R., Lovelace, R., Luethe, C., Phillips, L. M., Sewemaenewa, J., Sili, I., Waseta, B., Saad, M. F., Nicholas, S. B., Chen, Y. D. I., Guo, X., Rotter, J., Taylor, K., Budgett, M., Hariri, F., Zager, P., Shah, V., Scavini, M., Bobelu, A., Abboud, H., Arar, N., Duggirala, R., Kasinath, B. S., Thameem, F., Stern, M., Freedman, B. I., Bowden, D. W., Langefeld, C. D., Satko, S. C., Rich, S. S., Warren, S., Viverette, S., Brooks, G., Young, R., Spainhour, M., Winkler, C., Smith, M. W., Thompson, M., Hanson, R., Kessing, B., Leehey, D. J., Barone, G., Thornley-Brown, D., Jefferson, C., Kohn, O. F., Brown, C. S., Briggs, J. P., Kimmel, P. L., Rasooly, R., D. Warnock, W., Cardon, L., Chakraborty, R., Dunston, G. M., Hostetter, T., O'Brien, S. J., Rioux, J. & Spielman, R., May 4 2016, In : BMC genomics. 17, 1, 325.

Research output: Contribution to journalArticle

1 Scopus citations

The genetic architecture of type 2 diabetes

Fuchsberger, C., Flannick, J., Teslovich, T. M., Mahajan, A., Agarwala, V., Gaulton, K. J., Ma, C., Fontanillas, P., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Tajes, J. F., Highland, H. M. & 281 others, Dupuis, J., Chines, P. S., Lindgren, C. M., Hartl, C., Jackson, A. U., Chen, H., Huyghe, J. R., Van De Bunt, M., Pearson, R. D., Kumar, A., Müller-Nurasyid, M., Grarup, N., Stringham, H. M., Gamazon, E. R., Lee, J., Chen, Y., Scott, R. A., Below, J. E., Chen, P., Huang, J., Go, M. J., Stitzel, M. L., Pasko, D., Parker, S. C. J., Varga, T. V., Green, T., Beer, N. L., Day-Williams, A. G., Ferreira, T., Fingerlin, T., Horikoshi, M., Hu, C., Huh, I., Ikram, M. K., Kim, B. J., Kim, Y., Kim, Y. J., Kwon, M. S., Lee, J., Lee, S., Lin, K. H., Maxwell, T. J., Nagai, Y., Wang, X., Welch, R. P., Yoon, J., Zhang, W., Barzilai, N., Voight, B. F., Han, B. G., Jenkinson, C. P., Kuulasmaa, T., Kuusisto, J., Manning, A., Ng, M. C. Y., Palmer, N. D., Balkau, B., Stančáková, A., Abboud, H. E., Boeing, H., Giedraitis, V., Prabhakaran, D., Gottesman, O., Scott, J., Carey, J., Kwan, P., Grant, G., Smith, J. D., Neale, B. M., Purcell, S., Butterworth, A. S., Howson, J. M. M., Lee, H. M., Lu, Y., Kwak, S. H., Zhao, W., Danesh, J., Lam, V. K. L., Park, K. S., Saleheen, D., So, W. Y., Tam, C. H. T., Afzal, U., Aguilar, D., Arya, R., Aung, T., Chan, E., Navarro, C., Cheng, C. Y., Palli, D., Correa, A., Curran, J. E., Rybin, D., Farook, V. S., Fowler, S. P., Freedman, B. I., Griswold, M., Hale, D. E., Hicks, P. J., Khor, C. C., Kumar, S., Lehne, B., Thuillier, D., Lim, W. Y., Liu, J., Van Der Schouw, Y. T., Loh, M., Musani, S. K., Puppala, S., Scott, W. R., Yengo, L., Tan, S. T., Taylor, H. A., Thameem, F., Wilson, G., Wong, T. Y., Njolstad, P. R., Levy, J. C., Mangino, M., Bonnycastle, L. L., Schwarzmayr, T., Fadista, J., Surdulescu, G. L., Herder, C., Groves, C. J., Wieland, T., Bork-Jensen, J., Brandslund, I., Christensen, C., Koistinen, H. A., Doney, A. S. F., Kinnunen, L., Esko, T., Farmer, A. J., Hakaste, L., Hodgkiss, D., Kravic, J., Lyssenko, V., Hollensted, M., Jorgensen, M. E., Jorgensen, T., Ladenvall, C., Justesen, J. M., Käräjämäki, A., Kriebel, J., Rathmann, W., Lannfelt, L., Lauritzen, T., Narisu, N., Linneberg, A., Melander, O., Milani, L., Neville, M., Orho-Melander, M., Qi, L., Qi, Q., Roden, M., Rolandsson, O., Swift, A., Rosengren, A. H., Stirrups, K., Wood, A. R., Mihailov, E., Blancher, C., Carneiro, M. O., Maguire, J., Poplin, R., Shakir, K., Fennell, T., DePristo, M., De Angelis, M. H., Deloukas, P., Gjesing, A. P., Jun, G., Nilsson, P., Murphy, J., Onofrio, R., Thorand, B., Hansen, T., Meisinger, C., Hu, F. B., Isomaa, B., Karpe, F., Liang, L., Peters, A., Huth, C., O'Rahilly, S. P., Palmer, C. N. A., Pedersen, O., Rauramaa, R., Tuomilehto, J., Salomaa, V., Watanabe, R. M., Syvänen, A. C., Bergman, R. N., Bharadwaj, D., Bottinger, E. P., Cho, Y. S., Chandak, G. R., Chan, J. C. N., Chia, K. S., Daly, M. J., Ebrahim, S. B., Langenberg, C., Elliott, P., Jablonski, K. A., Lehman, D. M., Jia, W., Ma, R. C. W., Pollin, T. I., Sandhu, M., Tandon, N., Froguel, P., Barroso, I., Teo, Y. Y., Zeggini, E., Loos, R. J. F., Small, K. S., Ried, J. S., DeFronzo, R. A., Grallert, H., Glaser, B., Metspalu, A., Wareham, N. J., Walker, M., Banks, E., Gieger, C., Ingelsson, E., Im, H. K., Illig, T., Franks, P. W., Buck, G., Trakalo, J., Buck, D., Prokopenko, I., Mägi, R., Lind, L., Farjoun, Y., Owen, K. R., Gloyn, A. L., Strauch, K., Tuomi, T., Kooner, J. S., Lee, J. Y., Park, T., Donnelly, P., Morris, A. D., Hattersley, A. T., Bowden, D. W., Collins, F. S., Atzmon, G., Chambers, J. C., Spector, T. D., Laakso, M., Strom, T. M., Bell, G. I., Blangero, J., Duggirala, R., Tai, E. S., McVean, G., Hanis, C. L., Wilson, J. G., Seielstad, M., Frayling, T. M., Meigs, J. B., Cox, N. J., Sladek, R., Lander, E. S., Gabriel, S., Burtt, N. P., Mohlke, K. L., Meitinger, T., Groop, L., Abecasis, G., Florez, J. C., Scott, L. J., Morris, A. P., Kang, H. M., Boehnke, M., Altshuler, D. & McCarthy, M. I., Jul 11 2016, In : Nature. 536, 7614, p. 41-47 7 p.

Research output: Contribution to journalArticle

471 Scopus citations
5 Scopus citations
2015

Activation of AMP-Activated Protein Kinase Prevents TGF-β1-Induced Epithelial-Mesenchymal Transition and Myofibroblast Activation

Thakur, S., Viswanadhapalli, S., Kopp, J. B., Shi, Q., Barnes, J. L., Block, K., Gorin, Y. & Abboud, H. E., Aug 1 2015, In : American Journal of Pathology. 185, 8, p. 2168-2180 13 p.

Research output: Contribution to journalArticle

41 Scopus citations

Diabetic cardiomyopathy; Summary of 41 years

Yilmaz, S., Canpolat, U., Aydogdu, S. & Abboud, H. E., Jul 1 2015, In : Korean Circulation Journal. 45, 4, p. 266-272 7 p.

Research output: Contribution to journalReview article

35 Scopus citations
2 Scopus citations

Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND)

Iyengar, S. K., Sedor, J. R., Freedman, B. I., Kao, W. H. L., Kretzler, M., Keller, B. J., Abboud, H. E., Adler, S. G., Best, L. G., Bowden, D. W., Burlock, A., Chen, Y. D. I., Cole, S. A., Comeau, M. E., Curtis, J. M., Divers, J., Drechsler, C., Duggirala, R., Elston, R. C., Guo, X. & 39 others, Huang, H., Hoffmann, M. M., Howard, B. V., Ipp, E., Kimmel, P. L., Klag, M. J., Knowler, W. C., Kohn, O. F., Leak, T. S., Leehey, D. J., Li, M., Malhotra, A., März, W., Nair, V., Nelson, R. G., Nicholas, S. B., O’Brien, S. J., Pahl, M. V., Parekh, R. S., Pezzolesi, M. G., Rasooly, R. S., Rotimi, C. N., Rotter, J. I., Schelling, J. R., Seldin, M. F., Shah, V. O., Smiles, A. M., Smith, M. W., Taylor, K. D., Thameem, F., Thornley-Brown, D. P., Truitt, B. J., Wanner, C., Weil, E. J., Winkler, C. A., Zager, P. G., Igo, R. P., Hanson, R. L. & Langefeld, C. D., Aug 1 2015, In : PLoS Genetics. 11, 8, e1005352.

Research output: Contribution to journalArticle

54 Scopus citations

Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus

Mahajan, A., Sim, X., Ng, H. J., Manning, A., Rivas, M. A., Highland, H. M., Locke, A. E., Grarup, N., Im, H. K., Cingolani, P., Flannick, J., Fontanillas, P., Fuchsberger, C., Gaulton, K. J., Teslovich, T. M., Rayner, N. W., Robertson, N. R., Beer, N. L., Rundle, J. K., Bork-Jensen, J. & 243 others, Ladenvall, C., Blancher, C., Buck, D., Buck, G., Burtt, N. P., Gabriel, S., Gjesing, A. P., Groves, C. J., Hollensted, M., Huyghe, J. R., Jackson, A. U., Jun, G., Justesen, J. M., Mangino, M., Murphy, J., Neville, M., Onofrio, R., Small, K. S., Stringham, H. M., Syvänen, A. C., Trakalo, J., Abecasis, G., Bell, G. I., Blangero, J., Cox, N. J., Duggirala, R., Hanis, C. L., Seielstad, M., Wilson, J. G., Christensen, C., Brandslund, I., Rauramaa, R., Surdulescu, G. L., Doney, A. S. F., Lannfelt, L., Linneberg, A., Isomaa, B., Tuomi, T., Jørgensen, M. E., Jørgensen, T., Kuusisto, J., Uusitupa, M., Salomaa, V., Spector, T. D., Morris, A. D., Palmer, C. N. A., Collins, F. S., Mohlke, K. L., Bergman, R. N., Ingelsson, E., Lind, L., Tuomilehto, J., Hansen, T., Watanabe, R. M., Prokopenko, I., Dupuis, J., Karpe, F., Groop, L., Laakso, M., Pedersen, O., Florez, J. C., Morris, A. P., Altshuler, D., Meigs, J. B., Boehnke, M., McCarthy, M. I., Lindgren, C. M., Gloyn, A. L., Abboud, H. E., Afzal, U., Aguilar, D., Arya, R., Atzmon, G., Aung, T., Banks, E., Barroso, I., Barzilai, N., Below, J. E., Bharadwaj, D., Blackwell, T. W., Bonnycastle, L. L., Bowden, D., Carey, J., Carneiro, M. O., Chambers, J. C., Chan, E., Chan, J., Chandak, G. R., Chen, P., Chen, Y., Chen, H., Cheng, C. Y., Chia, K. S., Cho, Y. S., Correa, A., Curran, J. E., Daly, M. J., Day-Williams, A. G., DeFronzo, R. A., DePristo, M., Donnelly, P. J., Ebrahim, S. B., Elliott, P., Esko, T., Fadista, J., Farjoun, Y., Farmer, A. J., Farook, V. S., Fennell, T., Ferreira, T., Fingerlin, T., Forsén, T., Fowler, S. P., Franks, P. W., Frayling, T. M., Freedman, B. I., Froguel, P., Gamazon, E. R., Gieger, C., Glaser, B., Go, M. J., Goldstein, J. I., Grallert, H., Grant, G., Green, T., Griswold, M., Hale, D. E., Han, B. G., Hartl, C., Hattersley, A. T., Hicks, P. J., Hodgkiss, D., Horikoshi, M., Hrabé de Angelis, M., Hu, C., Hu, F. B., Huh, I., Kamran Ikram, M., Illig, T., Jablonski, K. A., Jenkinson, C. P., Jia, W., Kang, H. M., Khor, C. C., Kim, Y., Kim, Y. J., Kim, B. J., Kinnunen, L., Kooner, J. S., Kravic, J., Kriebel, J., Kumar, A., Kumar, S., Kuulasmaa, T., Kwon, M. S., Langenberg, C., Lauritzen, T., Lee, S., Lee, J., Lee, J., Lee, J. Y., Lehman, D. M., Lehne, B., Levy, J. C., Li, J., Liang, L., Lim, W. Y., Lin, K. H., Liu, J., Loh, M., Ma, R. C. W., Ma, C., Mägi, R., Maguire, J., Maxwell, T. J., McVean, G., Meisinger, C., Meitinger, T., Melander, O., Metspalu, A., Mihailov, E., Milani, L., Moutsianas, L., Müller-Nurasyid, M., K. Musani, S., Nagai, Y., Narisu, N., Neale, B. M., Ng, M. C. Y., Nilsson, P., O'Rahilly, S. P., Orho-Melander, M., Owen, K. R., Palmer, N. D., Park, T., Pasko, D., Pearson, R. D., Perry, J. R. B., Peters, A., Pollin, T. I., Poplin, R., Prabhakaran, D., Puppala, S., Purcell, S., Qi, L., Qi, Q., Roden, M., Rolandsson, O., Rosengren, A. H., Sandhu, M., Schwarzmayr, T., Scott, L. J., Scott, R. A., Scott, J., Scott, W. R., Sehmi, J., Shakir, K., Sladek, R., Smith, J. D., Stancáková, A., Strauch, K., Strom, T. M., Swift, A., Tai, E. S., Tajes, J. F., Tan, S. T., Tandon, N., Taylor, H. A., Teo, Y. Y., Thameem, F., Thorand, B., van de Bunt, M., Varga, T. V., Walker, M., Wareham, N. J., Welch, R. P., Wieland, T., Wilson, G., Wong, T. Y., Wood, A. R., Yoon, J., Zeggini, E. & Zhang, W., Jan 27 2015, In : PLoS Genetics. 11, 1, e1004876.

Research output: Contribution to journalArticle

57 Scopus citations

Layer-specific manganese-enhanced MRI of the diabetic rat retina in light and dark adaptation at 11.7 tesla

Muir, E. R., Chandra, S. B., De La Garza, B. H., Velagapudi, C., Abboud, H. E. & Duong, T. Q., 2015, In : Investigative Ophthalmology and Visual Science. 56, 6, p. 4006-4012 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Membranous nephropathy and cerebellar degeneration with anti-GAD antibodies in type 2 diabetes mellitus

Folli, F., Daniele, G., Werner, S., Kamath, S., Munera, J. V., Abboud, H. & Fanti, P., Mar 10 2015, (Accepted/In press) In : Acta Diabetologica.

Research output: Contribution to journalArticle

Metformin prevents renal interstitial fibrosis in mice with unilateral ureteral obstruction

Cavaglieri, R. C., Day, R. T., Feliers, D. & Abboud, H. E., Sep 5 2015, In : Molecular and Cellular Endocrinology. 412, p. 116-122 7 p.

Research output: Contribution to journalArticle

27 Scopus citations

NADPH oxidase 4 induces cardiac fibrosis and hypertrophy through activating Akt/mTOR and NFκB signaling pathways

Zhao, Q. D., Viswanadhapalli, S., Williams, P., Shi, Q., Tan, C., Yi, X., Bhandari, B. & Abboud, H. E., 2015, In : Circulation. 131, 7, p. 643-655 13 p.

Research output: Contribution to journalArticle

92 Scopus citations

Nox2 mediates skeletal muscle insulin resistance induced by a high fat diet

De Figueiredo, A. S. P., Salmon, A. B., Bruno, F., Jimenez, F., Martinez, H. G., Halade, G. V., Ahuja, S. S., Clark, R. A., DeFronzo, R. A., Abboud, H. E. & El Jamali, A., May 22 2015, In : Journal of Biological Chemistry. 290, 21, p. 13427-13439 13 p.

Research output: Contribution to journalArticle

46 Scopus citations

Targeting NADPH oxidase with a novel dual Nox1/Nox4 inhibitor attenuates renal pathology in type 1 diabetes

Gorin, Y., Cavaglieri, R. C., Khazim, K., Lee, D. Y., Bruno, F., Thakur, S., Fanti, P., Szyndralewiez, C., Barnes, J. L., Block, K. & Abboud, H. E., Jun 1 2015, In : American Journal of Physiology - Renal Physiology. 308, 11, p. F1276-F1287

Research output: Contribution to journalArticle

99 Scopus citations
2014

ADAM17 promotes proliferation of collecting duct kidney epithelial cells through ERK activation and increased glycolysis in polycystic kidney disease

Gooz Beck, M., Maldonado, E. N., Dang, Y., Amria, M. Y., Higashiyama, S., Abboud, H. E., Lemasters, J. J. & Bell, P. D., Sep 1 2014, In : American Journal of Physiology - Renal Physiology. 307, 5, p. F551-F559

Research output: Contribution to journalArticle

18 Scopus citations

A positive feedback loop involving Erk5 and Akt turns on mesangial cell proliferation in response to PDGF

Bera, A., Das, F., Ghosh-Choudhury, N., Li, X., Pal, S., Gorin, Y., Kasinath, B. S., Abboud, H. E. & Ghosh Choudhury, G., Jun 1 2014, In : American Journal of Physiology - Cell Physiology. 306, 11, p. C1089-C1100

Research output: Contribution to journalArticle

16 Scopus citations

Association of a low-frequency variant in HNF1A with type 2 diabetes in a latino population the SIGMA Type 2 Diabetes Consortium

The SIGMA Type 2 Diabetes Consortium, 2014, In : JAMA - Journal of the American Medical Association. 311, 22, p. 2305-2314 10 p.

Research output: Contribution to journalArticle

108 Scopus citations

Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes

The MAGIC investigators & The GIANT consortium, Aug 7 2014, In : PLoS Genetics. 10, 8, e1004517.

Research output: Contribution to journalArticle

111 Scopus citations

MicroRNA-21-induced dissociation of PDCD4 from rictor contributes to Akt-IKKβ-mTORC1 axis to regulate renal cancer cell invasion

Bera, A., Das, F., Ghosh-Choudhury, N., Kasinath, B. S., Abboud, H. E. & Choudhury, G. G., Oct 15 2014, In : Experimental Cell Research. 328, 1, p. 99-117 19 p.

Research output: Contribution to journalArticle

31 Scopus citations

Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico

Williams Amy, A. L., Jacobs Suzanne, S. B. R., Moreno-Macías, H., Huerta-Chagoya, A., Churchhouse, C., Márquez-Luna, C., Gómez-Vázquez, M. J., Burtt Noël, N. P., Aguilar-Salinas, C. A., González-Villalpando, C., Florez, J. C., Orozco, L., Tusié-Luna, T., Altshuler, D., Ripke, S., Manning, A. K., García-Ortíz, H., Neale, B., Reich, D., Stram, D. O. & 93 others, Fernández-López, J. C., Romero-Hidalgo, S., Patterson, N., Haiman, C. A., Aguilar-Delfín, I., Martínez-Hernández, A., Centeno-Cruz, F., Mendoza-Caamal, E., Revilla-Monsalve, C., Islas-Andrade, S., Córdova, E., Rodríguez-Arellano, E., Soberón, X., Florez Jose, J. C., González-Villalpando María Elena, M. A., Henderson, B. E., Monroe, K., Wilkens, L., Kolonel, L. N., Le Marchand, L., Riba, L., Ordóñez-Sánchez María Luisa, M. A., Rodríguez-Guillén, R., Cruz-Bautista, I., Rodríguez-Torres, M., Muñoz-Hernández, L. L., Sáenz, T., Gómez, D., Alvirde, U., Onofrio, R. C., Brodeur, W. M., Gage, D., Murphy, J., Franklin, J., Mahan, S., Ardlie, K., Crenshaw, A. T., Winckler, W., Prüfer, K., Shunkov, M. V., Sawyer, S., Stenzel, U., Kelso, J., Lek, M., Sankararaman, S., MacArthur, D. G., Derevianko, A. P., Pääbo, S., Jacobs, S. B. R., Gopal, S., Grammatikos, J. A., Smith, I. C., Bullock, K. H., Deik, A. A., Souza, A. L., Pierce, K. A., Clish, C. B., Fennell, T., Farjoun, Y., Gabriel, S., Gross, M. D., Pereira, M. A., Seielstad, M., Koh, W. P., Tai, E. S., Flannick, J., Fontanillas, P., Morris, A., Teslovich, T. M., Atzmon, G., Blangero, J., Bowden, D. W., Chambers, J., Cho, Y. S., Duggirala, R., Glaser, B., Hanis, C., Kooner, J., Laakso, M., Lee, J. Y., Teo, Y. Y., Wilson, J. G., Puppala, S., Farook, V. S., Thameem, F., Abboud, H. E., DeFronzo, R. A., Jenkinson, C. P., Lehman, D. M., Curran, J. E., Cortes, M. L., González-Villalpando Clicerio, C. & Orozco Lorena, L., 2014, In : Nature. 506, 7486, p. 97-101 5 p.

Research output: Contribution to journalArticle

255 Scopus citations

TGFβ-induced deptor suppression recruits mTORC1 and not mTORC2 to enhance collagen i (α2) gene expression

Das, F., Bera, A., Ghosh-Choudhury, N., Abboud, H. E., Kasinath, B. S. & Choudhury, G. G., Oct 15 2014, In : PloS one. 9, 10, e109608.

Research output: Contribution to journalArticle

24 Scopus citations
2013

ADAM17 mediates Nox4 expression and NADPH oxidase activity in the kidney cortex of OVE26 mice

Ford, B. M., Eid, A. A., Göoz, M., Barnes, J. L., Gorin, Y. C. & Abboud, H. E., Aug 1 2013, In : American Journal of Physiology - Renal Physiology. 305, 3, p. F323-F332

Research output: Contribution to journalArticle

22 Scopus citations

A genome-wide search for linkage of estimated glomerular filtration rate (eGFR) in the family investigation of nephropathy and diabetes (FIND)

Thameem, F., Igo, R. P., Freedman, B. I., Langefeld, C., Hanson, R. L., Schelling, J. R., Elston, R. C., Duggirala, R., Nicholas, S. B., Goddard, K. A. B., Divers, J., Guo, X., Ipp, E., Kimmel, P. L., Meoni, L. A., Shah, V. O., Smith, M. W., Winkler, C. A., Zager, P. G., Knowler, W. C. & 9 others, Nelson, R. G., Pahl, M. V., Parekh, R. S., Kao, W. H. L., Rasooly, R. S., Adler, S. G., Abboud, H. E., Iyengar, S. K. & Sedor, J. R., Dec 17 2013, In : PloS one. 8, 12, e81888.

Research output: Contribution to journalArticle

20 Scopus citations

Bardoxolone methyl in type 2 diabetes and stage 4 chronic kidney disease

De Zeeuw, D., Akizawa, T., Audhya, P., Bakris, G. L., Chin, M., Christ-Schmidt, H., Goldsberry, A., Houser, M., Krauth, M., Lambers Heerspink, H. J., McMurray, J. J., Meyer, C. J., Parving, H. H., Remuzzi, G., Toto, R. D., Vaziri, N. D., Wanner, C., Wittes, J., Wrolstad, D., Chertow, G. M. & 334 others, Toto, B., McCullough, P., Ivanovich, P., Ketteler, M., Lachin, J., McGill, J., Agarwal, R., Anker, S., Arenillas, J. F., Januzzi, J., Jardine, A., Kasner, S., Kissela, B., Kolansky, D., Mann, J., Thadhani, R., Champion de Crespigny, P., Chan, D. T., D'Almeida, E., Fraser, I., Gray, N., Holt, S., Irish, A., Isbel, N., Kerr, P., Packham, D., Phoon, R., Pollock, C., Roger, S., Suranyi, M., Walker, R., Wittert, G., Yue, D., Balcke, P., Prager, R., Schernthaner, G., Schernthaner, G., Sunder-Plassmann, G., Jadoul, M., Krzesinski, J. M., Peeters, P., Van der Niepen, P., Van Gaal, L., Van Vlem, B., Warling, X., Chow, S., Cournoyer, S., Dumas, R., Jolly, S., Levin, A., McMahon, A., Mehta, H., Ooi, T. C., Perkins, D., Roy, L., Sapir, D., Tam, P., Bartaskova, D., Hemzsky, L., Kubina, D., Szabo, M., Tesar, V., Combe, C., Faller, B., Fauvel, J. P., Halimi, J. M., Hourmant, M., Le Meur, Y., Urena-Torres, P., Zaoui, P., Al-Sarraf, S., Burst, V., Degenhardt, S., Kempe, H. P., Kleophas, W., Kosch, C., Krumme, B., Kuhlmann, M., Pistrosch, F., Rambausek, M., Schmidt-Guertler, H., Segiet, T., Sommerer, C., Vielhauer, V., Wanner, C., Beberashvili, I., Benchetrit, S., Herskovits, T., Karnieli, E., Levin-Iaina, N., Mosenzon, O., Tsur, A., van Dijk, D. J., Wainstein, J., Yagil, Y., Yerushalmi, Y., Colussi, G., Conte, G., Di Luca, M., Giovambatista, C., Messa, P., Pani, A., Pisani, A., Rapana, M. R., Ruggenenti, P., Villa, G., Zoccali, C., Correa-Rotter, R., Diaz-Escobedo, S. L., Garcia, P., Gonzalez Galvez, G., Obrador Vera, G. T., Rico, R., Calero, F., Cigarran, S., de Alvaro, F., de Francisco, A. L., Egido, J., Fernandez, E., Fernandez Vega, F., Fort, J., Galan Serrano, A., Gorriz Teruel, J. L., Martinez, I., Martinez Castelao, A., Munar, M. A., Navarro, J., Nieto, J., Osuna, A., Pascual, J., Portoles, J., Praga, M., Vallés, M., Fellstrom, B., Frisenette-Fich, C., Hadimeri, H., Stenvinkel, P., Svensson, M., Weiss, L., Adamson, K., Dornhorst, A., El Kossi, M., Gnudi, L., Hendry, B., Johnson, A., Joseph, F., Kalra, P., Marshall, S., Mikhail, A., Myint, K. S., Soran, H., Taal, M., Zehnder, D., Abbott, L., Acharya, A., Ahmed, Z., Aiello, J., Akom, M., Ali, S., Alzohaili, O., Anderson, L., Anderson, S., Anger, M., Appel, G., Arakaki, R. F., Arif, A., Assefi, A. R., Atray, N., Awad, A., Barranco, E., Belledonne, M. O., Belo, D., Bernardo, M., Bernstein, R., Bhalla, V., Bhatia, D., Black, R. M., Block, G., Blondin, J., Blumenthal, S. S., Bononi, P., Brantley, R. R., Bresssler, P., Broumand, V., Brusco, O., Buerkert, J., Burgos-Calderon, R., Campbell, R., Canas, G., Cangiano, J., Cherlin, R., Chilakapati, V., Comunale, R., Coyne, D., Crawford, P. W., Darwish, R., Deeb, W., Denker, P. S., Desai, S., Desouza, C., Diamond, S., Dixon, B. S., Durham, J. H., Eisner, G., Elder, J. G., El-Shahawy, M., Fadda, G., Fitz-Patrick, D., Fonseca, V., Fraser, N. J., Frei, G., Fried, L., Galindo-Ramos, E., Germain, M., Ghantous, W., Gilbert, J. M., Gillum, D., Godwin, J., Goel, A., Goldfarb, DS., Graf, R. J., Greenwood, T., Guasch, A., Hanna, A., Harper, K., Herman, T., Hilton, T., Hines, T., Hoggard, J., Hootkins, R., Huseman, R., Israelit, A., Jamal, A., Kant, K., Kaptein, E., Kathresal, A., Kaupke, J., Kaveh, K., Kaye, W., Keightley, G. E., Keith, K., Khairullah, Q., Kondle, V., Kopyt, N., Krishna, G., Lawrence, M. K., LeBeau, M., Leehey, D. J., Levine, M. M., Levinson, D., Lew, S. Q., Lewis, D., Linfert, D., Liss, K., Lund, R., Madeleine, P., Mahmood, K., Martin, E. R., Martinez, C., Mayeda, S. O., Mendez, R., Middleton, J., Molitch, M. E., Moncrief, J., Moustafa, M., Muoneke, R., Murray, A. V., Murugan, T. S., Nammour, T. M., Nassar, G., Navaneethan, S., Newman, J., Nossuli, A., Nwakoby, I., Osama, S., Ouseph, R., Parker, J., Parnes, E., Patel, N., Pergola, P., Perlman, A., Perry, R. G., Petrillo, R., Prabhakar, S., Purighalla, R. S., Quesada-Suarez, L., Rabiei, A., Raskin, P., Rastogi, A., Reisin, E., Rekhi, A., Rivera-Colon, L., Rizk, D., Rodelas, R., Roer, D., Rosas, S., Ross, D. L., Rovner, S., Sackel, H., Sader, S., Santos, P., Schmidt, R., Shafik, S., Shakeel, M., Sharon, Z., Silva, A. L., Silva, A., Singh, B., Smith, M., Solomon, R., Soman, S., Spinowitz, B., Sprague, S. M., Spry, L., Stonesifer, L., Streja, D., Suchinda, P., Sun, C., Thakar, C. V., Trespalacios, F., Tumlin, J. A., Van Buren, P., Vernace, M., Vicks, S., Warren, M., Weiss, D., Welker, J., Winston, J. A., Wombolt, D. G., Wood, M., Wu, M., Wynne, A., Yu, H. & Zabaneh, R. I., 2013, In : New England Journal of Medicine. 369, 26, p. 2492-2503 12 p.

Research output: Contribution to journalArticle

487 Scopus citations

Genome-wide association analysis confirms and extends the association of SLC2A9 with serum uric acid levels to mexican americans

Voruganti, V. S., Kent, J. W., Debnath, S., Cole, S. A., Haack, K., Göring, H. H. H., Carless, M. A., Curran, J. E., Johnson, M. P., Almasy, L., Dyer, T. D., MacCluer, J. W., Moses, E. K., Abboud, H. E., Mahaney, M. C., Blangero, J. & Comuzzie, A. G., Dec 1 2013, In : Frontiers in Genetics. 4, DEC, 00279.

Research output: Contribution to journalArticle

23 Scopus citations

Improving learning about familial risks using a multicomponent approach: the GRACE program

Arar, N., Delgado, E., Lee, S. & Abboud, H. E., Jan 1 2013, In : Personalized Medicine. 10, 1, p. 35-44 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Mammalian target of rapamycin regulates nox4-Mediated podocyte depletion in diabetic renal injury

Eid, A. A., Ford, B. M., Bhandary, B., Cavaglieri, R. D. C., Block, K., Barnes, J. L., Gorin, Y., Choudhury, G. G. & Abboud, H. E., Aug 1 2013, In : Diabetes. 62, 8, p. 2935-2947 13 p.

Research output: Contribution to journalArticle

89 Scopus citations

NFκB-mediated cyclin D1 expression by microRNA-21 influences renal cancer cell proliferation

Bera, A., Ghosh-Choudhury, N., Dey, N., Das, F., Kasinath, B. S., Abboud, H. E. & Choudhury, G. G., Dec 1 2013, In : Cellular Signalling. 25, 12, p. 2575-2586 12 p.

Research output: Contribution to journalArticle

36 Scopus citations

Susceptibility gene search for nephropathy and related traits in Mexican-Americans

Thameem, F., Kawalit, I. A., Adler, S. G. & Abboud, H. E., Oct 1 2013, In : Molecular Biology Reports. 40, 10, p. 5769-5779 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

Synthetic oleanane triterpenoids: Magic bullets or not?

Abboud, H. E., May 2013, In : Kidney international. 83, 5, p. 785-787 3 p.

Research output: Contribution to journalComment/debate

10 Scopus citations

The antioxidant silybin prevents high glucose-induced oxidative stress and podocyte injury in vitro and in vivo

Khazim, K., Gorin, Y., Cavaglieri, R. C., Abboud, H. E. & Fanti, P., Sep 1 2013, In : American Journal of Physiology - Renal Physiology. 305, 5, p. F691-F700

Research output: Contribution to journalArticle

68 Scopus citations

Transforming growth factor β integrates Smad 3 to mechanistic target of rapamycin complexes to arrest deptor abundance for glomerular mesangial cell hypertrophy

Das, F., Ghosh-Choudhury, N., Bera, A., Dey, N., Abboud, H. E., Kasinath, B. S. & Choudhury, G. G., Mar 15 2013, In : Journal of Biological Chemistry. 288, 11, p. 7756-7768 13 p.

Research output: Contribution to journalArticle

26 Scopus citations
2012

Diabetic nephropathy among Mexican Americans

Debnath, S., Thameem, F., Alves, T., Nolen, J., Hania, A. S., Bansal, S., Abboud, H. E. & Fanti, P., Apr 1 2012, In : Clinical Nephrology. 77, 4, p. 332-344 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

Genetic association and gene-gene interaction analyses in African American dialysis patients with nondiabetic nephropathy

Bostrom, M. A., Kao, W. H. L., Li, M., Abboud, H. E., Adler, S. G., Iyengar, S. K., Kimmel, P. L., Hanson, R. L., Nicholas, S. B., Rasooly, R. S., Sedor, J. R., Coresh, J., Kohn, O. F., Leehey, D. J., Thornley-Brown, D., Bottinger, E. P., Lipkowitz, M. S., Meoni, L. A., Klag, M. J., Lu, L. & 5 others, Hicks, P. J., Langefeld, C. D., Parekh, R. S., Bowden, D. W. & Freedman, B. I., Feb 1 2012, In : American Journal of Kidney Diseases. 59, 2, p. 210-221 12 p.

Research output: Contribution to journalArticle

30 Scopus citations

Hydrogen sulfide inhibits high glucose-induced matrix protein synthesis by activating AMP-activated protein kinase in renal epithelial cells

Lee, H. J., Mariappan, M. M., Feliers, D., Cavaglieri, R. C., Sataranatarajan, K., Abboud, H. E., Choudhury, G. G. & Kasinath, B. S., Feb 10 2012, In : Journal of Biological Chemistry. 287, 7, p. 4451-4461 11 p.

Research output: Contribution to journalArticle

76 Scopus citations

IGF-I increases the expression of fibronectin by Nox4-dependent Akt phosphorylation in renal tubular epithelial cells

New, D. D., Block, K., Bhandhari, B., Gorin, Y. & Abboud, H. E., Jan 1 2012, In : American Journal of Physiology - Cell Physiology. 302, 1, p. C122-C130

Research output: Contribution to journalArticle

40 Scopus citations

Mesangial cell biology

Abboud, H. E., May 15 2012, In : Experimental Cell Research. 318, 9, p. 979-985 7 p.

Research output: Contribution to journalReview article

124 Scopus citations