Find Research Outputs

2019

P110β in the ventromedial hypothalamus regulates glucose and energy metabolism

Fujikawa, T., Choi, Y. H., Yang, D. J., Shin, D. M., Donato, J., Kohno, D., Lee, C. E., Elias, C. F., Lee, S. & Kim, K. W., Apr 1 2019, In : Experimental and Molecular Medicine. 51, 4, 52.

Research output: Contribution to journalArticle

Open Access
Energy Metabolism
Hypothalamus
Neurons
Steroidogenic Factor 1
1-Phosphatidylinositol 4-Kinase
1 Citation (Scopus)

Pan-cancer genomic analyses reveal prognostic and immunogenic features of the tumor melatonergic microenvironment across 14 solid cancer types

Lv, J. W., Zheng, Z. Q., Wang, Z. X., Zhou, G. Q., Chen, L., Mao, Y. P., Lin, A. H., Reiter, R. J., Ma, J., Chen, Y. P. & Sun, Y., Jan 1 2019, In : Journal of pineal research. e12557.

Research output: Contribution to journalArticle

Tumor Microenvironment
Melatonin
Neoplasms
Uterine Cervical Neoplasms
Immunotherapy

Paternal benzo[a]pyrene exposure alters the sperm DNA methylation levels of imprinting genes in F0 generation mice and their unexposed F1-2 male offspring

Zhang, W., Yang, J., Lv, Y., Li, S. & Qiang, M., Aug 1 2019, In : Chemosphere. 228, p. 586-594 9 p.

Research output: Contribution to journalArticle

imprinting
Benzo(a)pyrene
Pyrene
methylation
Methylation

Patient-centered Involvement in Decision-Making: Ethnic Group and Sex as Indicators of Patients' Preferences and Perceptions

Perkins, H. S., Freed, A. A., Cortez, J. D. & Hazuda, H. P., Jul 1 2019, In : Medical Care. 57, 7, p. 521-527 7 p.

Research output: Contribution to journalArticle

Patient Preference
Ethnic Groups
Decision Making
Inpatients
African Americans

PCSK9 inhibitors and diabetes: Translational biology to clinical practice

Chilton, R. J., Oliveros, R. A., Gallegos, K. M. & Pham, S., Jan 1 2019, (Accepted/In press) In : Diabetes, Obesity and Metabolism.

Research output: Contribution to journalArticle

PD03-01 RNASEQ MICROBIAL ANALYSIS IDENTIFY VARIABILITY BETWEEN RENAL CELL CARCINOMA PRIMARY TUMOR AND INTRAVASCULAR TUMOR EXTENSION

Liss, M. A., Kaushik, D., Chen, Y., Johnson-pais, T. L., Pruthi, D., Mansour, A., White, J. & Rodriguez, R., Apr 1 2019, In : The Journal of urology. 201, p. e67

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Neoplasms
Thrombosis
Microbiota
Kidney Neoplasms

Pediatric cholestatic liver disease: Successful transition of care

Selvakumar, P. K. C., Hupertz, V., Mittal, N. K., Kowdley, K. V. & Alkhouri, N., Jul 1 2019, In : Cleveland Clinic Journal of Medicine. 86, 7, p. 454-464 11 p.

Research output: Contribution to journalReview article

Open Access
Patient Transfer
Liver Diseases
Pediatrics
Comorbidity
Young Adult

Percutaneous BCG enhances innate effector antitumor cytotoxicity during treatment of bladder cancer: a translational clinical trial

Ji, N., Mukherjee, N., Morales, E. E., Tomasini, M. E., Hurez, V., Curiel, T. J., Abate, G., Hoft, D. F., Zhao, X. R., Gelfond, J. A., Maiti, S., Cooper, L. J. N. & Svatek, R., Jan 1 2019, In : OncoImmunology.

Research output: Contribution to journalArticle

Urinary Bladder Neoplasms
Bacillus
Clinical Trials
Natural Killer T-Cells
Therapeutics

Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting in Treatment of Unprotected Left Main Stenosis

Taha, Y., Patel, R. A. G., Bagai, J., Sachdeva, R., Kumar, G., Prasad, A., Nathan, S. & Paul, T. K., May 1 2019, In : Current Cardiology Reports. 21, 5, 27.

Research output: Contribution to journalReview article

Percutaneous Coronary Intervention
Coronary Artery Bypass
Pathologic Constriction
Transplants
Patient Selection
1 Citation (Scopus)

Performance of PCA3 and TMPRSS2:ERG urinary biomarkers in prediction of biopsy outcome in the Canary Prostate Active Surveillance Study (PASS)

Newcomb, L. F., Zheng, Y., Faino, A. V., Bianchi-Frias, D., Cooperberg, M. R., Brown, M. D., Brooks, J. D., Dash, A., Fabrizio, M. D., Gleave, M. E., Liss, M. A., Morgan, T. M., Thompson, I. M., Wagner, A. A., Carroll, P. R., Nelson, P. S. & Lin, D. W., Jan 1 2019, (Accepted/In press) In : Prostate Cancer and Prostatic Diseases.

Research output: Contribution to journalArticle

Canaries
Prostate
Biomarkers
Biopsy
Decision Support Techniques

Persistent facial hyperpigmentation

Bailey, K. C., Wise, L. S., Breeden, T., Brodell, R. T. & Usatine, R. P., Jan 1 2019, In : Journal of Family Practice. 68, 1, p. 49-50 2 p.

Research output: Contribution to journalComment/debate

Hyperpigmentation

Pharmacokinetics of the Investigational Aurora A Kinase Inhibitor Alisertib in Adult Patients With Advanced Solid Tumors or Relapsed/Refractory Lymphoma With Varying Degrees of Hepatic Dysfunction

Zhou, X., Lockhart, A. C., Fu, S., Nemunaitis, J., Sarantopoulos, J., Muehler, A., Rangachari, L., Bargfrede, M. & Venkatakrishnan, K., Jan 1 2019, In : Journal of Clinical Pharmacology.

Research output: Contribution to journalArticle

Aurora Kinase A
Lymphoma
Pharmacokinetics
Liver
Neoplasms

Pharmacokinetic study of osimertinib in cancer patients with mild or moderate hepatic impairment

Grande, E., Donald Harvey, R., You, B., Batlle, J. F., Galbraith, H., Sarantopoulos, J., Ramalingam, S. S., Mann, H., So, K., Johnson, M. & Vishwanathan, K., May 1 2019, In : Journal of Pharmacology and Experimental Therapeutics. p. 291-299 9 p.

Research output: Contribution to journalArticle

Pharmacokinetics
Liver
Neoplasms
osimertinib
Safety

Phase 1/2 trial of glasdegib in patients with primary or secondary myelofibrosis previously treated with ruxolitinib

Gerds, A. T., Tauchi, T., Ritchie, E., Deininger, M., Jamieson, C., Mesa, R., Heaney, M., Komatsu, N., Minami, H., Su, Y., Shaik, N., Zhang, X., DiRienzo, C., Zeremski, M., Chan, G. & Talpaz, M., Apr 1 2019, In : Leukemia Research. 79, p. 38-44 7 p.

Research output: Contribution to journalArticle

Primary Myelofibrosis
Janus Kinases
Spleen
Dysgeusia
INCB018424

Phase 1 open-label, multicenter study of first-in-class RORγ agonist LYC-55716 (Cintirorgon): Safety, tolerability, and preliminary evidence of antitumor activity

Mahalingam, D., Wang, J. S., Hamilton, E. P., Sarantopoulos, J., Nemunaitis, J., Weems, G., Carter, L., Hu, X., Schreeder, M. & Wilkins, H. J., Jun 15 2019, In : Clinical Cancer Research. 25, 12, p. 3508-3516 9 p.

Research output: Contribution to journalArticle

Open Access
Multicenter Studies
Safety
Pharmacokinetics
Anemia
Hypophosphatemia

Phosphatidylethanolamine made in the inner mitochondrial membrane is essential for yeast cytochrome bc 1 complex function

Calzada, E., Avery, E., Sam, P. N., Modak, A., Wang, C., McCaffery, J. M., Han, X., Alder, N. N. & Claypool, S. M., Dec 1 2019, In : Nature communications. 10, 1, 1432.

Research output: Contribution to journalArticle

Electron Transport Complex III
cytochromes
yeast
Mitochondrial Membranes
Cytochromes

Physical activity change after a promotora-led intervention in low-income Mexican American women residing in South Texas

Salinas, J. J. & Parra-medina, D. M., Jun 20 2019, In : BMC Public Health. 19, 1, 782.

Research output: Contribution to journalArticle

Open Access
Exercise
Walking
Dancing
Leisure Activities
Mexico
1 Citation (Scopus)

Physical inactivity, cardiometabolic disease, and risk of dementia: An individual-participant meta-analysis

Kivimäki, M., Singh-Manoux, A., Pentti, J., Sabia, S., Nyberg, S. T., Alfredsson, L., Goldberg, M., Knutsson, A., Koskenvuo, M., Koskinen, A., Kouvonen, A., Nordin, M., Oksanen, T., Strandberg, T., Suominen, S. B., Theorell, T., Vahtera, J., Väänänen, A., Virtanen, M., Westerholm, P. & 9 others, Westerlund, H., Zins, M., Seshadri, S., Batty, G. D., Sipilä, P. N., Shipley, M. J., Lindbohm, J. V., Ferrie, J. E. & Jokela, M., Jan 1 2019, In : BMJ (Online). 365, l1495.

Research output: Contribution to journalArticle

Open Access
Dementia
Meta-Analysis
Alzheimer Disease
Causality
Cohort Studies
1 Citation (Scopus)

Pilot Study to Evaluate the Adjunct Use of a Povidone-Iodine Topical Antiseptic in Patients with Soft Tissue Abscesses

Olson, A. S., Rosenblatt, L., Salerno, N., Odette, J., Ren, R., Emanuel, T., Michalek, J. E., Liu, Q., Du, L., Jahangir, K. & Schmitz, G. R., Jan 1 2019, In : Journal of Emergency Medicine.

Research output: Contribution to journalArticle

Povidone-Iodine
Local Anti-Infective Agents
Abscess
Skin
Confidence Intervals
1 Citation (Scopus)

Pioglitazone: The forgotten, cost-effective cardioprotective drug for type 2 diabetes

Defronzo, R. A., Inzucchi, S., Abdul-ghani, M. A. & Nissen, S. E., Jan 1 2019, In : Diabetes and Vascular Disease Research.

Research output: Contribution to journalArticle

pioglitazone
Type 2 Diabetes Mellitus
Myocardial Infarction
Costs and Cost Analysis
Drug Costs

Pipecolic esters as minimized templates for proteasome inhibition

Giletto, M. B., Osmulski, P., Jones, C. L., Gaczynska, M. E. & Tepe, J. J., Jan 1 2019, In : Organic and Biomolecular Chemistry. 17, 10, p. 2734-2746 13 p.

Research output: Contribution to journalArticle

Proteasome Endopeptidase Complex
inhibitors
esters
Esters
templates

Pneumonia is a neglected problem: it is now time to act

Aliberti, S., Dela Cruz, C. S., Sotgiu, G. & Restrepo, M., Jan 1 2019, In : The Lancet Respiratory Medicine. 7, 1, p. 10-11 2 p.

Research output: Contribution to journalComment/debate

Pneumonia

Potential use of melatonin in skin cancer treatment: A review of current biological evidence

Pourhanifeh, M. H., Mahdavinia, M., Reiter, R. J. & Asemi, Z., Jan 1 2019, (Accepted/In press) In : Journal of Cellular Physiology.

Research output: Contribution to journalArticle

Oncology
Skin Neoplasms
Melatonin
Skin
Therapeutics

Practical considerations for managing breakthrough psychosis and symptomatic worsening in patients with schizophrenia on long-acting injectable antipsychotics

Correll, C. U., Sliwa, J. K., Najarian, D. M. & Saklad, S. R., Jan 1 2019, In : CNS Spectrums. p. 354-370 17 p.

Research output: Contribution to journalReview article

Open Access
Psychotic Disorders
Antipsychotic Agents
Schizophrenia
Injections
Critical Pathways

Preclinical activity of the antibody-drug conjugate denintuzumab mafodotin (SGN-CD19A) against pediatric acute lymphoblastic leukemia xenografts

Jones, L., McCalmont, H., Evans, K., Mayoh, C., Kurmasheva, R. T., Billups, C. A., Houghton, P. J., Smith, M. A. & Lock, R. B., Jan 1 2019, In : Pediatric Blood and Cancer. e27765.

Research output: Contribution to journalArticle

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Heterografts
Pediatrics
Antibodies
Pharmaceutical Preparations

Preclinical rationale for entinostat in embryonal rhabdomyosarcoma

Bharathy, N., Berlow, N. E., Wang, E., Abraham, J., Settelmeyer, T. P., Hooper, J. E., Svalina, M. N., Bajwa, Z., Goros, M. W., Hernandez, B. S., Wolff, J. E., Pal, R., Davies, A. M., Ashok, A., Bushby, D., Mancini, M., Noakes, C., Goodwin, N. C., Ordentlich, P., Keck, J. & 7 others, Hawkins, D. S., Rudzinski, E. R., Mansoor, A., Perkins, T. J., Vakoc, C. R., Michalek, J. E. & Keller, C., May 21 2019, In : Skeletal Muscle. 9, 1, 12.

Research output: Contribution to journalArticle

Open Access
Embryonal Rhabdomyosarcoma
Vincristine
Allografts
Heterografts
Rhabdomyosarcoma
1 Citation (Scopus)

Predicting drug response of tumors from integrated genomic profiles by deep neural networks

Chiu, Y. C., Chen, H. I. H., Zhang, T., Zhang, S., Gorthi, A., Wang, L. J., Huang, Y. & Chen, Y., Jan 31 2019, In : BMC Medical Genomics. 12, 18.

Research output: Contribution to journalArticle

Pharmaceutical Preparations
Neoplasms
Pharmacogenetics
Mutation
Neural Networks (Computer)

Predicting TMS-induced activation in human neocortex using concurrent TMS/PET, finite element analysis and computational modeling

Arabkheradmand, G., Krieg, T. D., Salinas, F. S., Fox, P. T. & Mogul, D. J., Jan 24 2019, In : Biomedical Physics and Engineering Express. 5, 2, 025028.

Research output: Contribution to journalArticle

Finite Element Analysis
Transcranial Magnetic Stimulation
Neocortex
Positron-Emission Tomography
Pyramidal Cells

Prediction of cardiovascular outcomes with machine learning techniques: Application to the cardiovascular outcomes in renal atherosclerotic lesions (CORAL) study

Chen, T., Brewster, P., Tuttle, K. R., Dworkin, L. D., Henrich, W. L., Greco, B. A., Steffes, M., Tobe, S., Jamerson, K., Pencina, K., Massaro, J. M., D’Agostino, R. B., Cutlip, D. E., Murphy, T. P., Cooper, C. J. & Shapiro, J. I., Jan 1 2019, In : International Journal of Nephrology and Renovascular Disease. 12, p. 49-58 10 p.

Research output: Contribution to journalArticle

Open Access
Kidney
Seeds
Decision Trees
Glycosylated Hemoglobin A
Group Psychotherapy

Prediction of Outcomes for Ruptured Aneurysm Surgery

Ban, V. S., El Ahmadieh, T. Y., Aoun, S. G., Plitt, A. R., Lyon, K. A., Eddleman, C., Beecher, J., McDougall, C. M., Reisch, J., Welch, B. G., Samson, D., Batjer, H. H. & White, J., Mar 1 2019, In : Stroke. 50, 3, p. 595-601 7 p.

Research output: Contribution to journalArticle

Ruptured Aneurysm
Odds Ratio
Aneurysm
Cerebral Hemorrhage
Hydrocephalus

Predictors of attendance and dropout in three randomized controlled trials of PTSD treatment for active duty service members

STRONG STAR Consortium, Jul 1 2019, In : Behaviour Research and Therapy. 118, p. 7-17 11 p.

Research output: Contribution to journalArticle

Post-Traumatic Stress Disorders
Randomized Controlled Trials
Therapeutics
Wounds and Injuries
Group Psychotherapy

Predictors of patency for arteriovenous fistulae and grafts in pediatric hemodialysis patients

on behalf of the Midwest Pediatric Nephrology Consortium, Feb 1 2019, In : Pediatric Nephrology. 34, 2, p. 329-339 11 p.

Research output: Contribution to journalArticle

Arteriovenous Fistula
Fistula
Blood Vessels
Renal Dialysis
Pediatrics

Predictors of Perceived Need for and Actual Action Taking Among Women in Violent Relationships

Katerndahl, D. A., Burge, S. K., Ferrer, R. L., Becho, J. & Wood, R., Aug 1 2019, In : Journal of Interpersonal Violence. 34, 16, p. 3344-3371 28 p.

Research output: Contribution to journalArticle

Stalking
Forgiveness
Violence
Safety
Drinking
1 Citation (Scopus)

Preferences for peer-reviewed versus other publication sources: a survey of general dentists in the National Dental PBRN

National Dental PBRN Collaborative Group, Mar 1 2019, In : Implementation science : IS. 14, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
Dentists
Tooth
Research
Economics
Publications
2 Citations (Scopus)

Prevalence and etiology of community-acquired pneumonia in immunocompromised patients

behalf of GLIMP Investigators, Jan 1 2019, In : Clinical Infectious Diseases. 68, 9, p. 1482-1493 12 p.

Research output: Contribution to journalArticle

Immunocompromised Host
Pneumonia
Acquired Immunodeficiency Syndrome
Neoplasms
Steroids

Prevalence and factors associated with dental caries in patients attending an HIV care clinic in Uganda: A cross sectional study

Kalanzi, D., Mayanja-Kizza, H., Nakanjako, D., Mwesigwa, C. L., Ssenyonga, R. & Amaechi, B. T., Jul 19 2019, In : BMC Oral Health. 19, 1, 159.

Research output: Contribution to journalArticle

Open Access
Uganda
Dental Caries
Cross-Sectional Studies
HIV
Tooth

Prevention of brain damage after traumatic brain injury by pharmacological enhancement of KCNQ (Kv7, “M-type”) K+ currents in neurons

Vigil, F. A., Bozdemir, E., Bugay, V., Chun, S. H., Hobbs, M. A., Sanchez, I., Hastings, S. D., Veraza, R. J., Holstein, D. M., Sprague, S. M., M Carver, C., Cavazos, J. E., Brenner, R., Lechleiter, J. D. & Shapiro, M. S., Jan 1 2019, In : Journal of Cerebral Blood Flow and Metabolism.

Research output: Contribution to journalArticle

Pharmacology
Neurons
Brain
Physiological Stress
Seizures
1 Citation (Scopus)

Prewash total motile count is a poor predictor of live birth in intrauterine insemination cycles

Mankus, E. B., Holden, A. E., Seeker, P. M., Kampschmidt, J. C., McLaughlin, J. E., Schenken, R. S. & Knudtson, J. F., Apr 1 2019, In : Fertility and Sterility. 111, 4, p. 708-713 6 p.

Research output: Contribution to journalArticle

Insemination
Live Birth
Birth Rate
Ovulation Induction
Infertility
1 Citation (Scopus)

Primary Care Physician Characteristics Associated with Low Value Care Spending

Barreto, T. W., Chung, Y., Wingrove, P., Young, R. A., Petterson, S., Bazemore, A. & Liaw, W., Mar 1 2019, In : Journal of the American Board of Family Medicine : JABFM. 32, 2, p. 218-225 8 p.

Research output: Contribution to journalArticle

Open Access
Primary Care Physicians
Medicare
American Medical Association
Medicine
1 Citation (Scopus)

Probing initial transient oligomerization events facilitating Huntingtin fibril nucleation at atomic resolution by relaxation-based NMR

Kotler, S. A., Tugarinov, V., Schmidt, T., Ceccon, A., Libich, D. S., Ghirlando, R., Schwieters, C. D. & Marius Clore, G., Feb 26 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 9, p. 3562-3571 10 p.

Research output: Contribution to journalArticle

Structural Models
Proline
Exons
polyglutamine
Huntingtin Protein

Proceedings from the Medical Summit on Firearm Injury Prevention: A Public Health Approach to Reduce Death and Disability in the US

Bulger, E. M., Kuhls, D. A., Campbell, B. T., Bonne, S., Cunningham, R. M., Betz, M., Dicker, R., Ranney, M. L., Barsotti, C., Hargarten, S., Sakran, J. V., Rivara, F. P., James, T., Lamis, D., Timmerman, G., Rogers, S. O., Choucair, B. & Stewart, R. M., Jan 1 2019, In : Journal of the American College of Surgeons.

Research output: Contribution to journalArticle

Firearms
Public Health
Wounds and Injuries
1 Citation (Scopus)

Progesterone Receptor Attenuates STAT1-Mediated IFN Signaling in Breast Cancer

Goodman, M. L., Trinca, G. M., Walter, K. R., Papachristou, E. K., D'Santos, C. S., Li, T., Liu, Q., Lai, Z., Chalise, P., Madan, R., Fan, F., Markiewicz, M. A., Jin, V. X., Carroll, J. S. & Hagan, C. R., May 15 2019, In : Journal of immunology (Baltimore, Md. : 1950). 202, 10, p. 3076-3086 11 p.

Research output: Contribution to journalArticle

Progesterone Receptors
Breast Neoplasms
Neoplasms
Genes
Ligands

Prolactin receptor expression in mouse dorsal root ganglia neuronal subtypes is sex-dependent

Patil, M., Hovhannisyan, A. H., Wangzhou, A., Mecklenburg, J., Koek, W., Goffin, V., Grattan, D., Boehm, U., Dussor, G., Price, T. J. & Akopian, A. N., Jan 1 2019, In : Journal of Neuroendocrinology. e12759.

Research output: Contribution to journalArticle

Prolactin Receptors
Spinal Ganglia
Sensory Receptor Cells
Neurons
Calcitonin Gene-Related Peptide Receptors

Prospective Clinical Sequencing of Adult Glioma

Zheng, S., Alfaro-Munoz, K., Wei, W., Wang, X., Wang, F., Eterovic, A. K., Shaw, K. R. M., Meric-Bernstam, F., Fuller, G. N., Chen, K., Verhaak, R. G., Mills, G. B., Yung, W. K. A., Weathers, S. P. & de Groot, J. F., May 1 2019, In : Molecular cancer therapeutics. 18, 5, p. 991-1000 10 p.

Research output: Contribution to journalArticle

Glioma
Glioblastoma
Mutation
Neoplasms
temozolomide
Point-of-Care Systems
Prostate
Area Under Curve
Fluoroquinolones
Anti-Bacterial Agents

Prospective Longitudinal Patient-Reported Satisfaction and Health-Related Quality of Life following DIEP Flap Breast Reconstruction: Relationship with Body Mass Index

Ochoa, O., Garza, R., Pisano, S., Chrysopoulo, M., Ledoux, P., Arishita, G., Ketchum, N., Michalek, J. E. & Nastala, C., Jun 1 2019, In : Plastic and reconstructive surgery. 143, 6, p. 1589-1600 12 p.

Research output: Contribution to journalArticle

Perforator Flap
Mammaplasty
Patient Satisfaction
Body Mass Index
Quality of Life
2 Citations (Scopus)
Melatonin
Astrocytes
Permeability
Reactive Oxygen Species
Ionomycin

Protocols to Study Dental Caries In Vitro: pH Cycling Models

Amaechi, B. T., Jan 1 2019, In : Methods in molecular biology (Clifton, N.J.). 1922, p. 379-392 14 p.

Research output: Contribution to journalArticle

Dental Caries
Toothpastes
Animal Testing Alternatives
Dentifrices
Fluorides

Protocols to Study Dental Caries In Vitro: Microbial Caries Models

Amaechi, B. T., Tenuta, L. M. A., Ricomini Filho, A. P. & Cury, J. A., Jan 1 2019, In : Methods in molecular biology (Clifton, N.J.). 1922, p. 357-368 12 p.

Research output: Contribution to journalArticle

Dental Caries
Biofilms
Dietary Sucrose
Tooth
In Vitro Techniques