Find Research Outputs

2019

Microhomology selection for Microhomology mediated end joining in Saccharomyces Cerevisiae

Lee, K., Ji, J. H., Yoon, K., Che, J., Seol, J. H., Lee, S. E. & Shim, E., Apr 1 2019, In : Genes. 10, 4, 254.

Research output: Contribution to journalArticle

Open Access
DNA End-Joining Repair
Saccharomycetales
DNA Breaks
Centromere
Endonucleases

Microtubule regulators act in the nervous system to modulate fat metabolism and longevity through DAF-16 in C. elegans

Xu, A., Zhang, Z., Ko, S. H., Fisher, A. L., Liu, Z. & Chen, L., Jan 1 2019, (Accepted/In press) In : Aging Cell. e12884.

Research output: Contribution to journalArticle

Microtubules
Nervous System
Fats
Genes
Tubulin Modulators

Microtubule-Targeting Drugs: More than Antimitotics

Kaul, R., Risinger, A. L. & Mooberry, S. L., Mar 22 2019, In : Journal of Natural Products. 82, 3, p. 680-685 6 p.

Research output: Contribution to journalReview article

Antimitotic Agents
Drug Delivery Systems
Microtubules
Biological Products
Pharmaceutical Preparations

Mild Physiologic Hyperglycemia Induces Hepatic Insulin Resistance in Healthy Normal Glucose-Tolerant Participants

Tripathy, D., Merovci, A., Basu, R., Abdul-ghani, M. A. & Defronzo, R. A., Jul 1 2019, In : The Journal of clinical endocrinology and metabolism. 104, 7, p. 2842-2850 9 p.

Research output: Contribution to journalArticle

Hyperglycemia
Insulin Resistance
Insulin
Glucose
Liver

Military Culture Considerations in Prolonged Exposure Therapy With Active-Duty Military Service Members

STRONG STAR Consortium, Jan 1 2019, (Accepted/In press) In : Cognitive and Behavioral Practice.

Research output: Contribution to journalArticle

Implosive Therapy
Post-Traumatic Stress Disorders
Afghanistan
Iraq
Military Personnel

Mitophagy activation repairs Leber's hereditary optic neuropathy-associated mitochondrial dysfunction and improves cell survival

Sharma, L. K., Tiwari, M., Rai, N. K. & Bai, Y., Feb 1 2019, In : Human Molecular Genetics. 28, 3, p. 422-433 12 p.

Research output: Contribution to journalArticle

Mitochondrial Degradation
Leber's Hereditary Optic Atrophy
Cell Survival
Autophagy
Mitochondrial DNA
2 Citations (Scopus)

Models and Studies of Aging: Executive Summary of a Report from the U13 Conference Series

Hurria, A., Carpenter, C. R., McFarland, F., Lundebjerg, N. E., de Cabo, R., Ferrucci, L., Studenski, S. A., Barzilai, N., Briggs, J. P., Ix, J. H., Kitzman, D. W., Kuchel, G. A., Musi, N., Newman, J. C., Rando, T. A., Smith, A. K., Walston, J. D., Kirkland, J. L. & Yung, R., Jan 1 2019, In : Journal of the American Geriatrics Society.

Research output: Contribution to journalArticle

Organized Financing
Research
Geriatrics
National Institute on Aging (U.S.)
Chronic Disease

Moderate Traumatic Brain Injury Alters the Gastrointestinal Microbiome in a Time-Dependent Manner

Nicholson, S. E., Watts, L. T., Burmeister, D. M., Merrill, D., Scroggins, S., Zou, Y., Lai, Z., Grandhi, R., Lewis, A. M., Newton, L. M., Eastridge, B. J. & Schwacha, M. G., Aug 1 2019, In : Shock (Augusta, Ga.). 52, 2, p. 240-248 9 p.

Research output: Contribution to journalArticle

Microbiota
Gastrointestinal Microbiome
Traumatic Brain Injury
Craniotomy
Human Body
Open Access
hippocampus
Neurons
Hippocampus
Dopamine
Modulation

Molecular Mechanisms of Membrane Curvature Sensing by a Disordered Protein

Zeno, W. F., Thatte, A. S., Wang, L., Snead, W. T., Lafer, E. M. & Stachowiak, J. C., Jul 3 2019, In : Journal of the American Chemical Society. 141, 26, p. 10361-10371 11 p.

Research output: Contribution to journalArticle

Proteins
Membranes
Entropy
Intrinsically Disordered Proteins
Static Electricity
1 Citation (Scopus)

Molecular Subtyping of Clinically Localized Urothelial Carcinoma Reveals Lower Rates of Pathological Upstaging at Radical Cystectomy Among Luminal Tumors

Lotan, Y., Boorjian, S. A., Zhang, J., Bivalacqua, T. J., Porten, S. P., Wheeler, T., Lerner, S. P., Hutchinson, R., Francis, F., Davicioni, E., Svatek, R., Chen, C., Black, P. C. & Gibb, E. A., Jan 1 2019, In : European Urology.

Research output: Contribution to journalArticle

Cystectomy
Carcinoma
Neoplasms
Urinary Bladder
Logistic Models

Motor Evoked Potential Recordings from the Urethral Sphincter Muscles (USMEPs) during Spine Surgeries

Jahangiri, F. R., Silverstein, J. W., Trausch, C., Al Eissa, S., George, Z. M., DeWal, H. & Tarasiewicz, I., Jan 2 2019, In : Neurodiagnostic Journal. 59, 1, p. 34-44 11 p.

Research output: Contribution to journalArticle

Motor Evoked Potentials
Urethra
Spine
Muscles
Urinary Bladder

Mouse models of severe asthma for evaluation of therapeutic cytokine targeting

Gubernatorova, E. O., Namakanova, O. A., Tumanov, A. V., Drutskaya, M. S. & Nedospasov, S. A., Mar 1 2019, In : Immunology Letters. 207, p. 73-83 11 p.

Research output: Contribution to journalReview article

Asthma
Cytokines
Biological Therapy
Therapeutics
Neutralizing Antibodies
1 Citation (Scopus)

mTORC1 underlies age-related muscle fiber damage and loss by inducing oxidative stress and catabolism

Tang, H., Inoki, K., Brooks, S. V., Okazawa, H., Lee, M., Wang, J., Kim, M., Kennedy, C. L., Macpherson, P. C. D., Ji, X., Van Roekel, S., Fraga, D. A., Wang, K., Zhu, J., Wang, Y., Sharp, Z. D., Miller, R. A., Rando, T. A., Goldman, D., Guan, K. L. & 1 others, Shrager, J. B., Jun 1 2019, In : Aging Cell. 18, 3, e12943.

Research output: Contribution to journalArticle

Open Access
Oxidative Stress
Muscles
Stress Fibers
Muscular Atrophy
Skeletal Muscle

mTOR in cerebrovascular disease

Van Skike, C. E. & Galvan Hart, V., Mar 15 2019, In : Aging. 11, 5, p. 1331-1332 2 p.

Research output: Contribution to journalEditorial

Cerebrovascular Disorders
Blood-Brain Barrier
Atherosclerosis
Alzheimer Disease

Multi-institutional multidisciplinary injury mortality investigation in the civilian pre-hospital environment (MIMIC): A methodology for reliably measuring prehospital time and distance to definitive care

Medrano, N. W., Villarreal, C. L., Price, M. A., Mackenzie, E., Nolte, K. B., Phillips, M. J., Stewart, R. M. & Eastridge, B. J., Apr 1 2019, In : Trauma Surgery and Acute Care Open. 4, 1, e000309.

Research output: Contribution to journalReview article

Open Access
Mortality
Wounds and Injuries
Emergency Medical Services
Coroners and Medical Examiners
Geographic Information Systems

Multisystem imaging review of human schistosomiasis: characteristic imaging findings

Nepal, P., Ojili, V., Songmen, S., Batchala, P., Kumar, D. & Nagar, A. M., Mar 1 2019, In : Clinical Imaging. 54, p. 163-171 9 p.

Research output: Contribution to journalReview article

Schistosomiasis
Parasitic Diseases
Emigration and Immigration
Human Body
Testis

Muscle-bone crosstalk and potential therapies for sarco-osteoporosis

Li, G. B., Zhang, L., Wang, D. E., AIQudsy, L., Jiang, J. X., Xu, H. Y. & Shang, P., Jan 1 2019, In : Journal of Cellular Biochemistry.

Research output: Contribution to journalArticle

Crosstalk
Osteoporosis
Muscle
Bone
Bone and Bones
1 Citation (Scopus)

Mutations in hmg1, Challenging the Paradigm of Clinical Triazole Resistance in Aspergillus fumigatus

Rybak, J. M., Ge, W., Wiederhold, N., Parker, J. E., Kelly, S. L., Rogers, P. D. & Fortwendel, J. R., Apr 2 2019, In : mBio. 10, 2

Research output: Contribution to journalArticle

Open Access
Triazoles
Aspergillus fumigatus
Mutation
Sterols
Aspergillosis
2 Citations (Scopus)

Myofibroblasts acquire retinoic acid–producing ability during fibroblast-to-myofibroblast transition following kidney injury

Nakamura, J., Sato, Y., Kitai, Y., Wajima, S., Yamamoto, S., Oguchi, A., Yamada, R., Kaneko, K., Kondo, M., Uchino, E., Tsuchida, J., Hirano, K., Sharma, K., Kohno, K. & Yanagita, M., Mar 1 2019, In : Kidney International. 95, 3, p. 526-539 14 p.

Research output: Contribution to journalArticle

Open Access
Myofibroblasts
Fibroblasts
Kidney
Retinaldehyde
Wounds and Injuries

Negative Life Events (NLEs) Contributing to Psychological Distress, Pain, and Disability in a U.S. Military Sample

Moreno, J. L., Nabity, P. S., Kanzler, K., Bryan, C. J., McGeary, C. A. & Mcgeary, D. D., Jan 1 2019, In : Military Medicine. 184, 1-2, p. e148-e155

Research output: Contribution to journalArticle

Psychology
Pain
Chronic Pain
Cognition
Suicidal Ideation

Network alterations in comorbid chronic pain and opioid addiction: An exploratory approach

Smallwood, R. F., Price, L. R., Campbell, J. L., Garrett, A. S., Atalla, S. W., Monroe, T. B., Aytur, S. A., Potter, J. S. & Robin, D. A., Feb 1 2019, In : Frontiers in Human Neuroscience. 13, 174.

Research output: Contribution to journalArticle

Open Access
Chronic Pain
Opioid Analgesics
Comorbidity
Pain
Low Back Pain

Neural correlates of emotion processing predict resilience in youth at familial risk for mood disorders

Nimarko, A. F., Garrett, A. S., Carlson, G. A. & Singh, M. K., Jan 1 2019, In : Development and Psychopathology.

Research output: Contribution to journalArticle

Parietal Lobe
Mood Disorders
Emotions
Prefrontal Cortex
Major Depressive Disorder
Open Access
Salts
Minocycline
Psychological Adaptation
Tumor Necrosis Factor-alpha
Calcium
1 Citation (Scopus)

Neuron-Derived Estrogen Regulates Synaptic Plasticity and Memory

Lu, Y., Sareddy, G. R., Wang, J., Wang, R., Li, Y., Dong, Y., Zhang, Q., Liu, J., O'connor, J., Xu, J., Vadlamudi, R. K. & Brann, D. W., Apr 10 2019, In : The Journal of neuroscience : the official journal of the Society for Neuroscience. 39, 15, p. 2792-2809 18 p.

Research output: Contribution to journalArticle

Open Access
Neuronal Plasticity
Prosencephalon
Estrogens
Aromatase
Neurons

Neurotrophic Proteins in Dentin and Their Effect on Trigeminal Sensory Neurons

Widbiller, M., Austah, O., Lindner, S. R., Sun, J. & Diogenes, A. R., Jan 1 2019, In : Journal of endodontics.

Research output: Contribution to journalArticle

Nerve Growth Factors
Sensory Receptor Cells
Dentin
Proteins
Neurotrophin 3

New concepts in diagnostics for invasive mycoses: Non-culture-based methodologies

Patterson, T. F. & Donnelly, J. P., Mar 1 2019, In : Journal of Fungi. 5, 1, 9.

Research output: Contribution to journalReview article

Open Access
mycoses
methodology
Aspergillus
Candida
well testing

Nodules, tumors, and hyperpigmented patches

Madden, J., Banta, J., Beachkofsky, T. & Usatine, R. P., Mar 1 2019, In : Journal of Family Practice. 68, 2, p. E17-E20

Research output: Contribution to journalArticle

Neoplasms

Non-alcoholic fatty liver disease, liver fibrosis score and cognitive function in middle-aged adults: The Framingham Study

Weinstein, G., Davis-Plourde, K., Himali, J. J., Zelber-Sagi, S., Beiser, A. S. & Seshadri, S., Jan 1 2019, In : Liver International.

Research output: Contribution to journalArticle

Liver Cirrhosis
Cognition
Fibrosis
Executive Function
Dementia

Novel Use of Household Items in Open and Robotic Surgical Skills Resident Education

Rowley, K., Pruthi, D., Al-Bayati, O., Basler, J. W. & Liss, M. A., Jan 1 2019, In : Advances in Urology. 2019, 5794957.

Research output: Contribution to journalArticle

Open Access
Robotics
Anatomic Models
Education
Aptitude
Urology

NURR1 activation in skeletal muscle controls systemic energy homeostasis

Amoasii, L., Sanchez-Ortiz, E., Fujikawa, T., Elmquist, J. K., Bassel-Duby, R. & Olson, E. N., Jan 1 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 166, 23, p. 11299-11308 10 p.

Research output: Contribution to journalArticle

Skeletal Muscle
Homeostasis
Glucose
Nuclear Receptor Subfamily 4, Group A, Member 2
Orphan Nuclear Receptors
4 Citations (Scopus)

Obesity in Aging Exacerbates Neuroinflammation, Dysregulating Synaptic Function-Related Genes and Altering Eicosanoid Synthesis in the Mouse Hippocampus: Potential Role in Impaired Synaptic Plasticity and Cognitive Decline

Valcarcel-Ares, M. N., Tucsek, Z., Kiss, T., Giles, C. B., Tarantini, S., Yabluchanskiy, A., Balasubramanian, P., Gautam, T., Galvan Hart, V., Ballabh, P., Richardson, A., Freeman, W. M., Wren, J. D., Deak, F., Ungvari, Z. & Csiszar, A., Feb 15 2019, In : The journals of gerontology. Series A, Biological sciences and medical sciences. 74, 3, p. 290-298 9 p.

Research output: Contribution to journalArticle

Open Access
Neuronal Plasticity
Eicosanoids
Hippocampus
Obesity
Long-Term Potentiation
5 Citations (Scopus)

Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis

Ogrodnik, M., Zhu, Y., Langhi, L. G. P., Tchkonia, T., Krüger, P., Fielder, E., Victorelli, S., Ruswhandi, R. A., Giorgadze, N., Pirtskhalava, T., Podgorni, O., Enikolopov, G., Johnson, K. O., Xu, M., Inman, C., Palmer, A. K., Schafer, M., Weigl, M., Ikeno, Y., Burns, T. C. & 4 others, Passos, J. F., von Zglinicki, T., Kirkland, J. L. & Jurk, D., May 7 2019, In : Cell Metabolism. 29, 5, p. 1061-1077.e8

Research output: Contribution to journalArticle

Open Access
Cell Aging
Neurogenesis
Anxiety
Obesity
Obese Mice
1 Citation (Scopus)

Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis

Ogrodnik, M., Zhu, Y., Langhi, L. G. P., Tchkonia, T., Krüger, P., Fielder, E., Victorelli, S., Ruswhandi, R. A., Giorgadze, N., Pirtskhalava, T., Podgorni, O., Enikolopov, G., Johnson, K. O., Xu, M., Inman, C., Palmer, A. K., Schafer, M., Weigl, M., Ikeno, Y., Burns, T. C. & 4 others, Passos, J. F., von Zglinicki, T., Kirkland, J. L. & Jurk, D., Jan 1 2019, (Accepted/In press) In : Cell Metabolism.

Research output: Contribution to journalArticle

Manuscripts
Cell Aging
Neurogenesis
Publications
Anxiety

Office-Based 532-Nanometer Pulsed Potassium-Titanyl-Phosphate Laser Procedures in Laryngology

Tibbetts, K. M. & Simpson, C. B., Jun 1 2019, In : Otolaryngologic Clinics of North America. 52, 3, p. 537-557 21 p.

Research output: Contribution to journalReview article

Solid-State Lasers
Otolaryngology
Laser Therapy
Lasers
Office Management

Oligodendrocytes regulate presynaptic properties and neurotransmission through bdnf signaling in the mouse brainstem

Jang, M., Gould, E., Xu, J., Kim, E. J. & Kim, J. H., Apr 1 2019, In : eLife. 8, e42156.

Research output: Contribution to journalArticle

Open Access
Brain-Derived Neurotrophic Factor
Oligodendroglia
Synaptic Transmission
Brain Stem
Tropomyosin
2 Citations (Scopus)

Omega-3 fatty acids and genome-wide interaction analyses reveal DPP10–pulmonary function association

Xu, J., Gaddis, N. C., Bartz, T. M., Hou, R., Manichaikul, A. W., Pankratz, N., Smith, A. V., Sun, F., Terzikhan, N., Markunas, C. A., Patchen, B. K., Schu, M., Beydoun, M. A., Brusselle, G. G., Eiriksdottir, G., Zhou, X., Wood, A. C., Graff, M., Harris, T. B., Arfan Ikram, M. & 30 others, Jacobs, D. R., Launer, L. J., Lemaitre, R. N., O’Connor, G. T., Oelsner, E. C., Psaty, B. M., Vasan, R. S., Rohde, R. R., Rich, S. S., Rotter, J. I., Seshadri, S., Smith, L. J., Tiemeier, H., Tsai, M. Y., Uitterlinden, A. G., Saroja Voruganti, V., Xu, H., Zilhão, N. R., Fornage, M., Carola Zillikens, M., London, S. J., Graham Barr, R., Dupuis, J., Gharib, S. A., Gudnason, V., Lahousse, L., North, K. E., Steffen, L. M., Cassano, P. A. & Hancock, D. B., Mar 1 2019, In : American Journal of Respiratory and Critical Care Medicine. 199, 5, p. 631-642 12 p.

Research output: Contribution to journalArticle

Omega-3 Fatty Acids
Genome
Single Nucleotide Polymorphism
Docosahexaenoic Acids
Respiratory Function Tests

Online Case-Sharing to Enhance Dental Students' Clinical Education: A Pilot Study

Oliveira, E. R., Rose, W. F. & Hendricson, W. D., Apr 1 2019, In : Journal of dental education. 83, 4, p. 416-422 7 p.

Research output: Contribution to journalArticle

Dental Students
Students
Education
education
Learning

Online yoga in myeloproliferative neoplasm patients: Results of a randomized pilot trial to inform future research

Huberty, J., Eckert, R., Dueck, A., Kosiorek, H., Larkey, L., Gowin, K. & Mesa, R., Jun 7 2019, In : BMC Complementary and Alternative Medicine. 19, 1, 121.

Research output: Contribution to journalArticle

Open Access
Yoga
Neoplasms
Sleep
Anxiety
Tumor Necrosis Factor-alpha

Open versus arthroscopic acromioclavicular joint resection: a systematic review and meta-analysis

Hohmann, E., Tetsworth, K. & Glatt, V., Jan 1 2019, (Accepted/In press) In : Archives of Orthopaedic and Trauma Surgery.

Research output: Contribution to journalArticle

Acromioclavicular Joint
Clavicle
Meta-Analysis
Publication Bias
Pain Measurement

Operative treatment of neer type-II distal clavicular fractures: An overview of contemporary techniques

Hohmann, E., Tetsworth, K. & Glatt, V., May 1 2019, In : JBJS Reviews. 7, 5, e5.

Research output: Contribution to journalReview article

Ligaments
2 Citations (Scopus)

Opportunities and Barriers for Family Physician Contribution to the Maternity Care Workforce

Barreto, T. W., Eden, A., Hansen, E. R. & Peterson, L. E., May 1 2019, In : Family medicine. 51, 5, p. 383-388 6 p.

Research output: Contribution to journalArticle

Open Access
Family Physicians
Obstetrics
Obstetric Delivery
Medicine
Life Style

Optimization of Differentiation of Nonhuman Primate Pluripotent Cells Using a Combinatorial Approach

Farnsworth, S. L., Qiu, Z., Mishra, A. & Hornsby, P. J., Jan 1 2019, In : Methods in molecular biology (Clifton, N.J.). 1919, p. 187-197 11 p.

Research output: Contribution to journalArticle

Pluripotent Stem Cells
Biological Factors
Primates
Cell Differentiation
Population

Optimizing the response, precision, and cost of a DNA double-strand break dosimeter

Obeidat, M., McConnell, K., Bui, B., Stathakis, S., Rasmussen, K., Papanikolaou, N., Shim, E. Y. & Kirby, N., May 21 2019, In : Physics in Medicine and Biology. 64, 10, 10NT02.

Research output: Contribution to journalArticle

Double-Stranded DNA Breaks
Costs and Cost Analysis
DNA
Microspheres
Radiation Dosimeters

Osteocytic connexin 43 channels affect fracture healing

Chen, Y., Chen, M., Xue, T., Li, G., Wang, D., Shang, P., Jiang, J. X. & Xu, H., Nov 1 2019, In : Journal of Cellular Physiology. 234, 11, p. 19824-19832 9 p.

Research output: Contribution to journalArticle

Connexin 43
Fracture Healing
Gap Junctions
Bone
Repair

Osteogain™ enhances the osteoinductive potential of demineralized bone matrix

Harrington, M., Cohen, D. J., Boyan, B. D. & Schwartz, Z., Jan 1 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Bone Matrix
Bone
Bone and Bones
Bone Regeneration
Bone Transplantation

Osteomyelitis: A Rare Complication After Subpectoral Biceps Tenodesis

Dang, K. H. & Dutta, A. K., Jan 1 2019, In : Orthopaedic Journal of Sports Medicine. 7, 1

Research output: Contribution to journalArticle

Tenodesis
Osteomyelitis

Outcomes of Genitourinary Injury in U.S. Iraq and Afghanistan War Veterans Receiving Care from the Veterans Health Administration

Nnamani, N. S., Pugh, M. J., Amuan, M. E., Eapen, B. C., Hudak, S. J., Liss, M. A. & Orman, J. A., Mar 1 2019, In : Military medicine. 184, 3-4, p. E297-E301

Research output: Contribution to journalArticle

Open Access
Veterans Health
Afghanistan
Iraq
United States Department of Veterans Affairs
Veterans

Outcomes of traumatic hemorrhagic shock and the epidemiology of preventable death from injury

Eastridge, B. J., Holcomb, J. B. & Shackelford, S., Apr 1 2019, In : Transfusion. 59, S2, p. 1423-1428 6 p.

Research output: Contribution to journalArticle

Open Access
Traumatic Shock
Hemorrhagic Shock
Epidemiology
Wounds and Injuries
Hemorrhage

Overview of complications of acute and chronic myocardial infarctions: Revisiting pathogenesis and cross-sectional imaging

Stephens, N. R., Restrepo, C. S., Saboo, S. S. & Baxi, A. J., Jan 1 2019, In : Postgraduate Medical Journal.

Research output: Contribution to journalReview article

Myocardial Infarction
Patient Care
Differential Diagnosis
Medicine
Morbidity