Find Research Outputs

2019
4 Citations (Scopus)

Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study

Justice, J. N., Nambiar, A. M., Tchkonia, T., LeBrasseur, N. K., Pascual, R., Hashmi, S. K., Prata, L., Masternak, M. M., Kritchevsky, S. B., Musi, N. & Kirkland, J. L., Jan 1 2019, (Accepted/In press) In : EBioMedicine.

Research output: Contribution to journalArticle

Idiopathic Pulmonary Fibrosis
Quercetin
Labels
Cell Aging
Phenotype

Sex-related disparities in CKD progression

CRIC Investigators, Jan 1 2019, In : Journal of the American Society of Nephrology. 30, 1, p. 137-146 10 p.

Research output: Contribution to journalArticle

Chronic Kidney Failure
Sex Characteristics
Social Adjustment
Biological Factors
Chronic Renal Insufficiency

Shar Pei Larynx: Supraglottic and Postcricoid Mucosal Redundancy and Its Association With Medical Comorbidities

Yiu, Y., Tibbetts, K. M., Simpson, C. B. & Matrka, L. A., Feb 1 2019, In : Annals of Otology, Rhinology and Laryngology. 128, 2, p. 121-127 7 p.

Research output: Contribution to journalArticle

Larynx
Comorbidity
Obstructive Sleep Apnea
Laryngopharyngeal Reflux
Obesity

Signaling characteristics and functional regulation of delta opioid-kappa opioid receptor (DOP-KOP) heteromers in peripheral sensory neurons

Jacobs, B. A., Pando, M. M., Jennings, E. M., Jamshidi, R. J., Zamora, J. C., Chavera, T. S., Clarke, W. P. & Berg, K. A., Jun 1 2019, In : Neuropharmacology. 151, p. 208-218 11 p.

Research output: Contribution to journalArticle

kappa Opioid Receptor
Enkephalins
Sensory Receptor Cells
Opioid Analgesics
Mitogen-Activated Protein Kinase 3

Socioeconomic Status and Long-Term Stroke Mortality, Recurrence and Disability in Iran: The Mashhad Stroke Incidence Study

Morovatdar, N., Thrift, A. G., Stranges, S., Kapral, M., Behrouz, R., Amiri, A., Heshmati, A., Ghahremani, A., Farzadfard, M. T., Mokhber, N. & Azarpazhooh, M. R., Jan 1 2019, In : Neuroepidemiology.

Research output: Contribution to journalArticle

Iran
Social Class
Cohort Studies
Stroke
Recurrence

Staff Perspectives on Primary Care Teams as De Facto “Hubs” for Care Coordination in VA: a Qualitative Study

Olmos-Ochoa, T. T., Bharath, P., Ganz, D. A., Noel, P. H., Chawla, N., Barnard, J. M., Rose, D. E., Stockdale, S. E., Simon, A. & Finley Garcia, E., Jan 1 2019, In : Journal of General Internal Medicine.

Research output: Contribution to journalArticle

Veterans Health
United States Department of Veterans Affairs
Patient Care Team
Primary Health Care
Interviews

Synthesis, preliminarily biological evaluation and molecular docking study of new Olaparib analogues as multifunctional PARP-1 and cholinesterase inhibitors

Gao, C. Z., Dong, W., Cui, Z. W., Yuan, Q., Hu, X. M., Wu, Q. M., Han, X., Xu, Y. & Min, Z. L., Dec 1 2019, In : Journal of Enzyme Inhibition and Medicinal Chemistry. 34, 1, p. 150-162 13 p.

Research output: Contribution to journalArticle

Cholinesterase Inhibitors
Alzheimer Disease
Enzymes
Electrophorus
Neostigmine
1 Citation (Scopus)

Synthesis and SAR of novel capsazepine analogs with significant anti-cancer effects in multiple cancer types

Chapa, J. D. L., Valdez, M., Ruiz, F., Gonzales, K., Mitchell, W., McHardy, S. F., Hart, M., Polusani, S. R. & Gonzales, C. B., Jan 1 2019, In : Bioorganic and Medicinal Chemistry. 27, 1, p. 208-215 8 p.

Research output: Contribution to journalArticle

Cells
Lead compounds
Tumors
Nude Mice
Neoplasms

Systematic review of civilian intravascular ballistic embolism reports during the last 30 years

Kuo, A. H., Gregorat, A. E., Restrepo, C. S. & Vinu-Nair, S., Jan 1 2019, In : Journal of Vascular Surgery.

Research output: Contribution to journalReview article

Embolism
Wounds and Injuries
Gunshot Wounds
Ischemia
Torso

Systematic Review of Intrathecal Nicardipine for the Treatment of Cerebral Vasospasm in Aneurysmal Subarachnoid Hemorrhage

Hafeez, S. & Grandhi, R., Jan 1 2019, (Accepted/In press) In : Neurocritical Care.

Research output: Contribution to journalArticle

Intracranial Vasospasm
Nicardipine
Subarachnoid Hemorrhage
Spinal Injections
Therapeutics

Systematic review of modifiable risk factors for kidney cancer

Al-Bayati, O., Hasan, A., Pruthi, D., Kaushik, D. & Liss, M. A., Jan 1 2019, (Accepted/In press) In : Urologic Oncology: Seminars and Original Investigations.

Research output: Contribution to journalArticle

Kidney Neoplasms
Renal Cell Carcinoma
Obesity
Smoking
Alcohols

Temporal dynamic reorganization of 3D chromatin architecture in hormone-induced breast cancer and endocrine resistance

Zhou, Y., Gerrard, D. L., Wang, J., Li, T., Yang, Y., Fritz, A. J., Rajendran, M., Fu, X., Schiff, R., Lin, S., Frietze, S. & Jin, V. X., Dec 1 2019, In : Nature communications. 10, 1, 1522.

Research output: Contribution to journalArticle

Open Access
chromatin
hormones
breast
Chromatin
cancer

TGF-2 uses the concave surface of its extended finger region to bind betaglycan’s ZP domain via three residues specific to TGF- and inhibin-

Henen, M. A., Mahlawat, P., Zwieb, C. W., Kodali, R. B., Hinck, C. S., Hanna, R. D., Krzysiak, T. C., Ilangovan, U., Cano, K. E., Hinck, G., Vonberg, M., McCabe, M. & Hinck, A. P., Jan 1 2019, In : Journal of Biological Chemistry. 294, 9, p. 3065-3080 16 p.

Research output: Contribution to journalArticle

Inhibins
Transforming Growth Factors
Fingers
Binding Sites
Bone Morphogenetic Protein 2

The ability of a cytomegalovirus ELISPOT assay to predict outcome of low-level CMV reactivation in hematopoietic cell transplant recipients

El Haddad, L., Ariza-Heredia, E., Shah, D. P., Jiang, Y., Blanchard, T., Ghantoji, S. S., El Chaer, F., El-Haddad, D., Prayag, A., Nesher, L., Rezvani, K., Shpall, E. & Chemaly, R. F., Feb 23 2019, In : Journal of Infectious Diseases. 219, 6, p. 898-907 10 p.

Research output: Contribution to journalArticle

Enzyme-Linked Immunospot Assay
Cytomegalovirus
Transplants
Infection
Cytomegalovirus Infections
1 Citation (Scopus)

The alteration landscape of the cerebral cortex

Cauda, F., Nani, A., Manuello, J., Liloia, D., Tatu, K., Vercelli, U., Duca, S., Fox, P. T. & Costa, T., Jan 1 2019, In : NeuroImage. 184, p. 359-371 13 p.

Research output: Contribution to journalArticle

Brain Diseases
Entropy
Cerebral Cortex
Brain
Temporal Lobe

The Association between Inflammatory Markers in the Acute Phase of Stroke and Long-Term Stroke Outcomes: Evidence from a Population-Based Study of Stroke

Mobarra, N., Morovatdar, N., Di Napoli, M., Stranges, S., Behrouz, R., Amiri, A., Farzadfard, M. T., Hashemy, S. I., Oskoii, R., Khorram, B. & Azarpazhooh, M. R., Jan 1 2019, In : Neuroepidemiology.

Research output: Contribution to journalArticle

Stroke
C-Reactive Protein
Population
Recurrence
Reactive Oxygen Species

The combination of a neprilysin inhibitor (sacubitril) and angiotensin-II receptor blocker (valsartan) attenuates glomerular and tubular injury in the Zucker Obese rat

Habibi, J., Aroor, A. R., Das, N. A., Manrique-Acevedo, C. M., Johnson, M. S., Hayden, M. R., Nistala, R., Wiedmeyer, C., Chandrasekar, B. & Demarco, V. G., Mar 25 2019, In : Cardiovascular Diabetology. 18, 1, 40.

Research output: Contribution to journalArticle

Open Access
Valsartan
Zucker Rats
Neprilysin
Angiotensin Receptor Antagonists
Diabetic Nephropathies

The dynamics of partner violence and alcohol use in couples: Research methods

Burge, S. K., Katerndahl, D. A., Becho, J., Wood, R., Rodriguez, J. & Ferrer, R. L., Feb 1 2019, In : Violence and Victims. 34, 1, p. 136-156 21 p.

Research output: Contribution to journalArticle

Violence
research method
alcohol
Alcohols
violence

The effects of melatonin supplementation on blood pressure in patients with metabolic disorders: a systematic review and meta-analysis of randomized controlled trials

Akbari, M., Ostadmohammadi, V., Mirhosseini, N., Lankarani, K. B., Tabrizi, R., Keshtkaran, Z., Reiter, R. J. & Asemi, Z., Jan 1 2019, (Accepted/In press) In : Journal of Human Hypertension.

Research output: Contribution to journalArticle

Melatonin
Meta-Analysis
Randomized Controlled Trials
Blood Pressure
PubMed
Implosive Therapy
Military Personnel
Post-Traumatic Stress Disorders
Randomized Controlled Trials
Veterans
1 Citation (Scopus)

The Fungal Cyp51-Specific Inhibitor VT-1598 Demonstrates In Vitro and In Vivo Activity against Candida auris

Wiederhold, N., Lockhart, S. R., Najvar, L. K., Berkow, E. L., Jaramillo, R., Olivo, M., Garvey, E. P., Yates, C. M., Schotzinger, R. J., Catano, G. & Patterson, T. F., Mar 1 2019, In : Antimicrobial agents and chemotherapy. e02233-18.

Research output: Contribution to journalArticle

caspofungin
Fluconazole
Candida
14-alpha Demethylase Inhibitors
Kidney

The intraoperative accuracy of maxillary balloon dilation: a blinded trial

Jensen, B. T., Holbrook, E. H., Chen, P. G., Luong, A. U., Marino, M. J. & Yao, W. C., Jan 1 2019, (Accepted/In press) In : International Forum of Allergy and Rhinology.

Research output: Contribution to journalArticle

Dilatation
Maxillary Sinus
Nasal Polyps
Nose
Cadaver
1 Citation (Scopus)

The multiple protective roles and molecular mechanisms of melatonin and its precursor N-acetylserotonin in targeting brain injury and liver damage and in maintaining bone health

Luo, C., Yang, Q., Liu, Y., Zhou, S., Jiang, J., Reiter, R. J., Bhattacharya, P., Cui, Y., Yang, H., Ma, H., Yao, J., Lawler, S. E., Zhang, X., Fu, J., Rozental, R., Aly, H., Johnson, M. D., Chiocca, E. A. & Wang, X., Jan 1 2019, In : Free Radical Biology and Medicine. 130, p. 215-233 19 p.

Research output: Contribution to journalReview article

Melatonin
Liver
Brain Injuries
Brain
Bone

The novel capsazepine analog, CIDD-99, significantly inhibits oral squamous cell carcinoma in vivo through a TRPV1-independent induction of ER stress, mitochondrial dysfunction, and apoptosis

De La Chapa, J. J., Singha, P. K., Self, K. K., Sallaway, M. L., McHardy, S. F., Hart, M. J., Mcguff, H. S., Valdez, M. C., Ruiz, F., Polusani, S. R. & Gonzales, C. B., Jan 1 2019, In : Journal of Oral Pathology and Medicine.

Research output: Contribution to journalArticle

Transient Receptor Potential Channels
Squamous Cell Carcinoma
Apoptosis
Neoplasms
Calcium

The plasmid-encoded PGP3 promotes chlamydia evasion of acidic barriers in both stomach and vagina

Zhang, T., Huo, Z., Ma, J., He, C. & Zhong, G., May 1 2019, In : Infection and Immunity. 87, 5, e00844-18.

Research output: Contribution to journalArticle

Chlamydia muridarum
Chlamydia
Vagina
Stomach
Plasmids
10 Citations (Scopus)

Therapeutic potential of melatonin related to its role as an autophagy regulator: A review

Boga, J. A., Caballero, B., Potes, Y., Perez-Martinez, Z., Reiter, R. J., Vega-Naredo, I. & Coto-Montes, A., Jan 1 2019, In : Journal of Pineal Research. 66, 1, e12534.

Research output: Contribution to journalReview article

Autophagy
Melatonin
Pathology
Physiological Phenomena
Endoplasmic Reticulum Stress
1 Citation (Scopus)

Therapy for Pulmonary Arterial Hypertension in Adults: Update of the CHEST Guideline and Expert Panel Report

Klinger, J. R., Elliott, C. G., Levine, D. J., Bossone, E., Duvall, L., Fagan, K., Frantsve-Hawley, J., Kawut, S. M., Ryan, J. J., Rosenzweig, E. B., Sederstrom, N., Steen, V. D. & Badesch, D. B., Mar 1 2019, In : Chest. 155, 3, p. 565-586 22 p.

Research output: Contribution to journalArticle

Pulmonary Hypertension
Guidelines
Consensus
Therapeutics
Delphi Technique

The re-emerging association between tuberculosis and diabetes: Lessons from past centuries

Cadenazuluaga, J., Rathinavelu, S., Lopez-Alvarenga, J. C. & Restrepo, B. I., Jan 1 2019, In : Tuberculosis.

Research output: Contribution to journalArticle

Tuberculosis
Diabetes Mellitus
Type 2 Diabetes Mellitus
Comorbidity
Diabetic Coma

The relationship between gait and functional outcomes in patients treated with circular external fixation for malunited tibial fractures

Manjra, M. A., Naude, J., Birkholtz, F., Glatt, V., Tetsworth, K. & Hohmann, E., Feb 1 2019, In : Gait and Posture. 68, p. 569-574 6 p.

Research output: Contribution to journalArticle

Malunited Fractures
Tibial Fractures
Gait
Foot
Lower Extremity
Doppler Transcranial Ultrasonography
Subarachnoid Hemorrhage

The role of familial risk, parental psychopathology, and stress for first-onset depression during adolescence

Elsayed, N. M., Fields, K. M., Olvera, R. L. & Williamson, D. E., Jun 15 2019, In : Journal of Affective Disorders. 253, p. 232-239 8 p.

Research output: Contribution to journalArticle

Psychopathology
Depression
Major Depressive Disorder
Appointments and Schedules
Mothers

The Role of Glucagon-Like Peptide-1 in Energy Homeostasis

Salehi, M. & Purnell, J. Q., May 1 2019, In : Metabolic Syndrome and Related Disorders. 17, 4, p. 183-191 9 p.

Research output: Contribution to journalReview article

Glucagon-Like Peptide 1
Homeostasis
Brain
Incretins
Appetite

The role of melatonin in targeting cell signaling pathways in neurodegeneration

Shukla, M., Chinchalongporn, V., Govitrapong, P. & Reiter, R. J., Jan 1 2019, In : Annals of the New York Academy of Sciences.

Research output: Contribution to journalReview article

Cell signaling
Melatonin
Neurodegenerative Diseases
Neurodegenerative diseases
Proteostasis Deficiencies

The therapeutic role of long non-coding RNAs in human diseases: A focus on the recent insights into autophagy

Barangi, S., Hayes, A. W., Reiter, R. J. & Karimi, G., Apr 1 2019, In : Pharmacological Research. 142, p. 22-29 8 p.

Research output: Contribution to journalReview article

Long Noncoding RNA
Autophagy
Therapeutics
Biological Phenomena
Untranslated RNA
Percutaneous Coronary Intervention
Acute Kidney Injury
Dialysis
Population

Tolerance doses for late adverse events after hypofractionated radiotherapy for prostate cancer on trial NRG Oncology/RTOG 0415

Thor, M., Deasy, J. O., Paulus, R., Robert Lee, W., Amin, M. B., Bruner, D. W., Low, D. A., Shah, A. B., Malone, S. C., Michalski, J. M., Dayes, I. S., Seaward, S. A., Gore, E. M., Albert, M., Pisansky, T. M., Faria, S. L., Chen, Y., Koontz, B. F., Swanson, G. P., Pugh, S. L. & 1 othersSandler, H. M., Jun 1 2019, In : Radiotherapy and Oncology. 135, p. 19-24 6 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Radiotherapy
Area Under Curve
Rectum
Urinary Bladder

Transcriptome analysis of the human tibial nerve identifies sexually dimorphic expression of genes involved in pain, inflammation, and neuro-immunity

Ray, P. R., Khan, J., Wangzhou, A., Tavares-Ferreira, D., Akopian, A. N., Dussor, G. & Price, T. J., Feb 12 2019, In : Frontiers in Molecular Neuroscience. 12, 37.

Research output: Contribution to journalArticle

Open Access
Tibial Nerve
Gene Expression Profiling
Immunity
Sex Characteristics
Chronic Pain
Military Personnel
Post-Traumatic Stress Disorders
Cognition
Emotions
Catastrophization

Treatment data using a topical povidone-iodine antiseptic in patients with superficial skin abscesses

Schmitz, G., Rosenblatt, L., Salerno, N., Odette, J., Ren, R., Emanuel, T., Michalek, J. E., Liu, Q., Du, L., Jahangir, K. & Olson, A. S., Apr 1 2019, In : Data in Brief. 23, 103715.

Research output: Contribution to journalArticle

Open Access
Povidone-Iodine
Local Anti-Infective Agents
Abscess
Skin
Hand Sanitizers
Motivational Interviewing
Alcohols
Therapeutics
Program Evaluation
Ambulatory Care Facilities

Treatment of malocclusion after TMJ disc repositioning with Mitek anchors. A retrospective review

Perez, D., Brown, Z. L., Amarista, F. J. & Pham, M., Jan 1 2019, In : Journal of Stomatology, Oral and Maxillofacial Surgery.

Research output: Contribution to journalArticle

Temporomandibular Joint Disc
Malocclusion
Therapeutics
Open Bite
Temporomandibular Joint

Triaging Inpatient Admissions: an Opportunity for Resident Education

Wang, E. S., Velásquez, S. T., Smith, C. J., Matthias, T. H., Schmit, D., Hsu, S. & Leykum, L. K., Jan 1 2019, In : Journal of General Internal Medicine.

Research output: Contribution to journalArticle

Inpatients
Internal Medicine
Education
Medicine
Physicians

Trpm2 enhances physiological bioenergetics and protects against pathological oxidative cardiac injury: Role of Pyk2 phosphorylation

Miller, B. A., Wang, J. F., Song, J., Zhang, X. Q., Hirschler-Laszkiewicz, I., Shanmughapriya, S., Tomar, D., Rajan, S., Feldman, A. M., Muniswamy, M., Sheu, S. S. & Cheung, J. Y., Jan 1 2019, (Accepted/In press) In : Journal of Cellular Physiology.

Research output: Contribution to journalArticle

Focal Adhesion Kinase 2
Phosphorylation
Energy Metabolism
Muscle Cells
Wounds and Injuries

Tutorial on lipidomics

Wang, J., Wang, C. & Han, X., Jan 1 2019, In : Analytica Chimica Acta.

Research output: Contribution to journalReview article

body fluid
Body fluids
Body Fluids
Biological systems
Mass spectrometry

Upcycling umbilical cords: bridging regenerative medicine with neonatology

Moreira, A. G., Alayli, Y., Balgi, S., Winter, C., Kahlenberg, S., Mustafa, S. & Hornsby, P. J., Apr 18 2019, In : Journal of Maternal-Fetal and Neonatal Medicine. 32, 8, p. 1378-1387 10 p.

Research output: Contribution to journalReview article

Neonatology
Regenerative Medicine
Umbilical Cord
Mesenchymal Stromal Cells
Premature Infants

Using microRNA-122 mimics or microRNA-451 inhibitors to prevent the osteoarthritis process

Scott, K. M., Hays, M., Cohen, D. J., Schwartz, Z. & Boyan, B. D., Jan 1 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

MicroRNAs
Osteoarthritis
Enzymes
Matrix Metalloproteinase 13
RNA

Variables associated with reductions in insomnia severity among acutely suicidal patients receiving brief cognitive behavioral therapy for suicide prevention

Roberge, E. M., Bryan, C. J., Peterson, A. L. & Rudd, M. D., Jun 1 2019, In : Journal of Affective Disorders. 252, p. 230-236 7 p.

Research output: Contribution to journalArticle

Sleep Initiation and Maintenance Disorders
Cognitive Therapy
Suicide
Sleep
Military Personnel

Veterans’ Use of Programs and Services as They Transition to Civilian Life: Baseline Assessment for the Veteran Metrics Initiative

Perkins, D. F., Aronson, K. R., Morgan, N. R., Bleser, J. A., Vogt, D., Copeland, L. A., Finley Garcia, E. & Gilman, C., Jan 1 2019, (Accepted/In press) In : Journal of Social Service Research.

Research output: Contribution to journalArticle

reintegration
assistance
housing
mobile social services
service provider

What is the Standard of Care for Pelvic Lymphadenectomy Performed at the Time of Radical Cystectomy?

Lerner, S. P. & Svatek, R., Jan 1 2019, (Accepted/In press) In : European Urology.

Research output: Contribution to journalArticle

Cystectomy
Standard of Care
Lymph Node Excision
3 Citations (Scopus)

Wide-neck bifurcation aneurysms of the middle cerebral artery and basilar apex treated by endovascular techniques: A multicentre, core lab adjudicated study evaluating safety and durability of occlusion (BRANCH)

De Leacy, R. A., Fargen, K. M., Mascitelli, J. R., Fifi, J., Turkheimer, L., Zhang, X., Patel, A. B., Koch, M. J., Pandey, A. S., Wilkinson, D. A., Griauzde, J., James, R. F., Fortuny, E. M., Cruz, A., Boulos, A., Nourollah-Zadeh, E., Paul, A., Sauvageau, E., Hanel, R., Aguilar-Salinas, P. & 8 othersNovakovic, R. L., Welch, B. G., Almardawi, R., Jindal, G., Shownkeen, H., Levy, E. I., Siddiqui, A. H. & Mocco, J., Jan 1 2019, In : Journal of NeuroInterventional Surgery. 11, 1, p. 31-36 6 p.

Research output: Contribution to journalArticle

Endovascular Procedures
Intracranial Aneurysm
Aneurysm
Neck
Middle Cerebral Artery