Find Research Outputs

2019

A dynamic and integrated epigenetic program at distal regions orchestrates transcriptional responses to VEGFA

Wang, S., Chen, J., Garcia, S. P., Liang, X., Zhang, F., Yan, P., Yu, H., Wei, W., Li, Z., Wang, J., Le, H., Han, Z., Luo, X., Day, D. S., Stevens, S. M., Zhang, Y., Park, P. J., Liu, Z., Sun, K., Yuan, G. C. & 2 others, Pu, W. T. & Zhang, B., Feb 1 2019, In : Genome Research. 29, 2, p. 193-207 15 p.

Research output: Contribution to journalArticle

Open Access
Epigenomics
Gene Expression
Transcription Factors
Chromatin
Histone Code

Age- And sex-specific plasticity in dopamine transporter function revealed by food restriction and exercise in a rat activity-based anorexia paradigm

Lee Gilman, T., Anthony Owens, W., George, C. M., Metzel, L., Vitela, M., Ferreira, L., Bowman, M. A., Gould, G. G., Toney, G. M. & Daws, L. C., Jan 1 2019, In : Journal of Pharmacology and Experimental Therapeutics. 371, 2, p. 268-277 10 p.

Research output: Contribution to journalArticle

Open Access
Dopamine Plasma Membrane Transport Proteins
Anorexia
Exercise
Food
Cocaine

A genome-wide association study identifies genetic loci associated with specific lobar brain volumes

van der Lee, S. J., Knol, M. J., Chauhan, G., Satizabal, C. L., Smith, A. V., Hofer, E., Bis, J. C., Hibar, D. P., Hilal, S., van den Akker, E. B., Arfanakis, K., Bernard, M., Yanek, L. R., Amin, N., Crivello, F., Cheung, J. W., Harris, T. B., Saba, Y., Lopez, O. L., Li, S. & 42 others, van der Grond, J., Yu, L., Paus, T., Roshchupkin, G. V., Amouyel, P., Jahanshad, N., Taylor, K. D., Yang, Q., Mathias, R. A., Boehringer, S., Mazoyer, B., Rice, K., Cheng, C. Y., Maillard, P., van Heemst, D., Wong, T. Y., Niessen, W. J., Beiser, A. S., Beekman, M., Zhao, W., Nyquist, P. A., Chen, C., Launer, L. J., Psaty, B. M., Ikram, M. K., Vernooij, M. W., Schmidt, H., Pausova, Z., Becker, D. M., De Jager, P. L., Thompson, P. M., van Duijn, C. M., Bennett, D. A., Slagboom, P. E., Schmidt, R., Longstreth, W. T., Ikram, M. A., Seshadri, S., Debette, S., Gudnason, V., Adams, H. H. H. & DeCarli, C., Dec 1 2019, In : Communications Biology. 2, 1, 285.

Research output: Contribution to journalArticle

Open Access
Genetic Loci
Genome-Wide Association Study
Occipital Lobe
Brain
Genes
1 Citation (Scopus)

A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology

INVENT Consortium, MEGASTROKE Consortium of the International Stroke Genetics Consortium, Jan 1 2019, In : Blood. 133, 9, p. 967-977 11 p.

Research output: Contribution to journalArticle

Factor VII
Genome-Wide Association Study
Genes
Stroke
Mendelian Randomization Analysis

A genome-wide association study of prostate cancer in Latinos

Du, Z., Hopp, H., Ingles, S. A., Huff, C., Sheng, X., Weaver, B., Stern, M., Hoffmann, T. J., John, E. M., Van Den Eeden, S. K., Strom, S., Leach, R. J., Thompson, I. M., Witte, J. S., Conti, D. V. & Haiman, C. A., Jan 1 2019, (Accepted/In press) In : International Journal of Cancer.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Hispanic Americans
Prostatic Neoplasms
Population
Genome

Agent-Based Modeling of Day-to-Day Intimate Partner Violence

Katerndahl, D. A., Burge, S., Ferrer, R. L., Becho, J., Wood, R. & Villacampa, M. D. M., Apr 1 2019, In : Nonlinear dynamics, psychology, and life sciences. 23, 2, p. 275-296 22 p.

Research output: Contribution to journalArticle

Agent-based Modeling
Alcohol
Multiple Time Series
Agent-based Model
Continuous Variables
1 Citation (Scopus)

Aging Induces an Nlrp3 Inflammasome-Dependent Expansion of Adipose B Cells That Impairs Metabolic Homeostasis

Camell, C. D., Günther, P., Lee, A., Goldberg, E. L., Spadaro, O., Youm, Y. H., Bartke, A., Hubbard, G. B., Ikeno, Y., Ruddle, N. H., Schultze, J. & Dixit, V. D., Dec 3 2019, In : Cell Metabolism. 30, 6, p. 1024-1039.e6

Research output: Contribution to journalArticle

Inflammasomes
Homeostasis
B-Lymphocytes
Adipose Tissue
Lipolysis
1 Citation (Scopus)

Aging research using the common marmoset: Focus on aging interventions

Ross, C. N. & Salmon, A. B., Jan 1 2019, In : Nutrition and Healthy Aging. 5, 2, p. 97-109 13 p.

Research output: Contribution to journalReview article

Callithrix
Callithrix jacchus
translation (genetics)
Aging of materials
Callitrichidae

A hindbrain inhibitory microcircuit mediates vagally-coordinated glucose regulation

Boychuk, C., Smith, K. C., Peterson, L. E., Boychuk, J. A., Butler, C. R., Derera, I. D., McCarthy, J. J. & Smith, B. N., Dec 1 2019, In : Scientific Reports. 9, 1, 2722.

Research output: Contribution to journalArticle

Open Access
Rhombencephalon
Designer Drugs
Solitary Nucleus
Neurons
Glucose
1 Citation (Scopus)

AKI Associated with Acute Pancreatitis

Nassar, T. I. & Qunibi, W. Y., Jul 5 2019, In : Clinical journal of the American Society of Nephrology : CJASN. 14, 7, p. 1106-1115 10 p.

Research output: Contribution to journalArticle

Pancreatitis
Acute Necrotizing Pancreatitis
Renal Replacement Therapy
Respiratory Insufficiency
Renal Insufficiency
2 Citations (Scopus)

A lack of decline in major nontraumatic amputations in Texas: Contemporary trends, risk factor associations, and impact of revascularization

Garcia, M., Hernandez, B., Ellington, T. G., Kapadia, A., Michalek, J. E., Fisher-Hoch, S., McCormick, J. B. & Prasad, A., Jun 1 2019, In : Diabetes care. 42, 6, p. 1061-1066 6 p.

Research output: Contribution to journalArticle

Amputation
Lower Extremity
Odds Ratio
Hispanic Americans
Inpatients
21 Citations (Scopus)

Altered bile acid profile associates with cognitive impairment in Alzheimer's disease—An emerging role for gut microbiome

Alzheimer's Disease Neuroimaging Initiative and the Alzheimer Disease Metabolomics Consortium, Jan 1 2019, In : Alzheimer's and Dementia. 15, 1, p. 76-92 17 p.

Research output: Contribution to journalArticle

Open Access
Bile Acids and Salts
Alzheimer Disease
Cholic Acid
Deoxycholic Acid
Brain
10 Citations (Scopus)

Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: Relationship to neuroimaging and CSF biomarkers

Alzheimer's Disease Neuroimaging Initiative and the Alzheimer Disease Metabolomics Consortium, Feb 1 2019, In : Alzheimer's and Dementia. 15, 2, p. 232-244 13 p.

Research output: Contribution to journalArticle

Bile Acids and Salts
Neuroimaging
Cerebrospinal Fluid
Alzheimer Disease
Biomarkers

Altered expression of aquaporin 1 and aquaporin 5 in the cornea after primary blast exposure

Ríos, J. D., Choi, J. H., McDaniel, J. S., Becera, S., Bice, L., Johnson, P., Cleland, J. M., Glickman, R. D., Reilly, M. A., Gray, W., Sponsel, W. E. & Lund, B. J., Jan 1 2019, In : Molecular vision. 25, p. 283-294 12 p.

Research output: Contribution to journalArticle

Aquaporin 5
Aquaporin 1
Cornea
Rabbits
Edema
1 Citation (Scopus)

Alveolar Septal Widening as an "Alert" Signal to Look Into Lung Antibody-mediated Rejection: A Multicenter Pilot Study

Calabrese, F., Hirschi, S., Neil, D., Montero-Fernandez, A., Timens, W., Verbeken, E., Chenard, M. P., Ivanovic, M., Le Pavec, J., Pena, T., Dorfmüller, P., Roux, A., Rice, A., Perissinotto, E., Lunardi, F., Levine, D. J., Cozzi, E. & Goddard, M., Nov 1 2019, In : Transplantation. 103, 11, p. 2440-2447 8 p.

Research output: Contribution to journalArticle

Multicenter Studies
Lung
Antibodies
Acute Lung Injury
Wounds and Injuries

A machine learning model for the prediction of survival and tumor subtype in pancreatic ductal adenocarcinoma from preoperative diffusion-weighted imaging

Kaissis, G., Ziegelmayer, S., Lohöfer, F., Algül, H., Eiber, M., Weichert, W., Schmid, R., Friess, H., Rummeny, E., Ankerst, D., Siveke, J. & Braren, R., Dec 1 2019, In : European Radiology Experimental. 3, 1, 41.

Research output: Contribution to journalArticle

Open Access
Adenocarcinoma
Survival
Neoplasms
ROC Curve
Area Under Curve
1 Citation (Scopus)

AMBN mutations causing hypoplastic amelogenesis imperfecta and Ambn knockout-NLS-lacZ knockin mice exhibiting failed amelogenesis and Ambn tissue-specificity

Liang, T., Hu, Y., Smith, C. E., Richardson, A. S., Zhang, H., Yang, J., Lin, B., Wang, S. K., Kim, J. W., Chun, Y. P., Simmer, J. P. & Hu, J. C. C., Jan 1 2019, (Accepted/In press) In : Molecular Genetics and Genomic Medicine. e929.

Research output: Contribution to journalArticle

Open Access
Amelogenesis
Organ Specificity
Dental Enamel
Ameloblasts
Dentin

Amended Safety Assessment of Methylisothiazolinone as Used in Cosmetics

Burnett, C. L., Boyer, I., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., Marks, J. G., Shank, R. C., Slaga, T. J., Snyder, P. W., Gill, L. J. & Heldreth, B., May 1 2019, In : International Journal of Toxicology. 38, 1_suppl, p. 70S-84S

Research output: Contribution to journalArticle

Cosmetics
Safety
Risk assessment
Animals
2-methyl-4-isothiazolin-3-one
Program Evaluation
Violence
Wounds and Injuries
Health Services Needs and Demand
Exposure to Violence

A modular PROTAC design for target destruction using a degradation signal based on a single amino acid

Shanmugasundaram, K., Shao, P., Chen, H., Campos, B., McHardy, S. F., Luo, T. & Rao, H., Jan 1 2019, In : Journal of Biological Chemistry. 294, 41, p. 15172-15175 4 p.

Research output: Contribution to journalArticle

Proteolysis
Amino Acids
Degradation
Ubiquitin
Estrogen Receptors

AMP-activated protein kinase activation ameliorates eicosanoid dysregulation in high-fat-induced kidney disease in mice

Declèves, A. E., Mathew, A. V., Armando, A. M., Han, X., Dennis, E. A., Quehenberger, O. & Sharma, K., May 1 2019, In : Journal of lipid research. 60, 5, p. 937-952 16 p.

Research output: Contribution to journalArticle

AMP-Activated Protein Kinases
Eicosanoids
Kidney Diseases
High Fat Diet
Nutrition
2 Citations (Scopus)
Sodium alginate
biofilms
Chitosan
Biofilms
Biocompatible Materials

A Multicenter Evaluation of a Firearm Safety Intervention in the Pediatric Outpatient Setting

Campbell, B. T., Thaker, S., Fallat, M. E., Foley, D. S., McClure, E., Sakran, J. V., Nasr, I. W., Ziegfeld, S., Ehrlich, P. F., Snodgrass, M., Levy, M., Naik-Mathuria, B. J., Johnson, B., Demello, A. S., Jones, S., Watters, J. M., Burke, P., Allee, L., Kozyckyj, T., Letton, R. W. & 3 others, Kuhls, D. A., Bulger, E. M. & Stewart, R. M., Jan 1 2019, (Accepted/In press) In : Journal of Pediatric Surgery.

Research output: Contribution to journalReview article

Firearms
Outpatients
Pediatrics
Safety
Parents

A mutually induced conformational fit underlies Ca 2 -directed interactions between calmodulin and the proximal C terminus of KCNQ4 K channels

Archer, C. R., Enslow, B. T., Taylor, A. B., De la Rosa, V., Bhattacharya, A. & Shapiro, M. S., Jan 1 2019, In : Journal of Biological Chemistry. 294, 15, p. 6094-6112 19 p.

Research output: Contribution to journalArticle

Calmodulin
Peptides
Thermophoresis
Calorimetry
X ray crystallography

Anacolosins A-F and Corymbulosins X and Y, Clerodane Diterpenes from Anacolosa clarkii Exhibiting Cytotoxicity toward Pediatric Cancer Cell Lines

Cai, S., Risinger, A. L., Petersen, C. L., Grkovic, T., O'Keefe, B. R., Mooberry, S. L. & Cichewicz, R. H., Jan 1 2019, In : Journal of Natural Products.

Research output: Contribution to journalArticle

Clerodane Diterpenes
Pediatrics
Cytotoxicity
Biological Products
Hepatoblastoma
1 Citation (Scopus)

Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by APOE Genotype

Ma, Y., Jun, G. R., Zhang, X., Chung, J., Naj, A. C., Chen, Y., Bellenguez, C., Hamilton-Nelson, K., Martin, E. R., Kunkle, B. W., Bis, J. C., Debette, S., Destefano, A. L., Fornage, M., Nicolas, G., Van Duijn, C., Bennett, D. A., De Jager, P. L., Mayeux, R., Haines, J. L. & 6 others, Pericak-Vance, M. A., Seshadri, S., Lambert, J. C., Schellenberg, G. D., Lunetta, K. L. & Farrer, L. A., Jan 1 2019, (Accepted/In press) In : JAMA Neurology.

Research output: Contribution to journalArticle

Exome
Alzheimer Disease
Genotype
Alleles
Odds Ratio
1 Citation (Scopus)

Analysis of Wide-Neck Aneurysms in the Barrow Ruptured Aneurysm Trial

Mascitelli, J. R., Lawton, M. T., Hendricks, B. K., Nakaji, P., Zabramski, J. M. & Spetzler, R. F., Nov 1 2019, In : Clinical Neurosurgery. 85, 5, p. 622-631 10 p.

Research output: Contribution to journalArticle

Ruptured Aneurysm
Aneurysm
Neck
Surgical Instruments
Retreatment

Analytical challenges of shotgun lipidomics at different resolution of measurements

Wang, J. & Han, X., Dec 2019, In : TrAC - Trends in Analytical Chemistry. 121, 115697.

Research output: Contribution to journalReview article

Mass spectrometry
Electrospray ionization
Body fluids
Ionization
Desorption

A National Needs Assessment of Point-of-Care Ultrasound Training for Hospitalists

LoPresti, C. M., Boyd, J. S., Schott, C., Core, M., Lucas, B. P., Colon-Molero, A., Kessler, C., Mader, M. J., Haro, E. K., Finley Garcia, E., Restrepo, M. I., Pugh, J. A. & Soni, N. J., Sep 1 2019, In : Mayo Clinic Proceedings. 94, 9, p. 1910-1912 3 p.

Research output: Contribution to journalLetter

Point-of-Care Systems
Hospitalists
Needs Assessment

An Epidemiological Evaluation of Trauma Types in a Cohort of Deployed Service Members

Presseau, C., Litz, B. T., Kline, N. K., Elsayed, N. M., Maurer, D., Kelly, K., Dondanville, K. A., Mintz, J., Young-mccaughan, S., Peterson, A. L. & Williamson, D. E., Jan 1 2019, In : Psychological Trauma: Theory, Research, Practice, and Policy.

Research output: Contribution to journalArticle

Wounds and Injuries
Mental Health
Violence
Post-Traumatic Stress Disorders
Research

Anesthetic Errors during Procedures in the United States

Singh, P., Maita, M., Lacci, J., Boies, B., Revere, A. S., Sirak, E. T. & Seifi, A., Sep 1 2019, In : Southern Medical Journal. 112, 9, p. 491-496 6 p.

Research output: Contribution to journalArticle

Open Access
Anesthetics
Mortality
Comorbidity
Hospital Mortality
Electrolytes
1 Citation (Scopus)

A neural signature of metabolic syndrome

Kotkowski, E., Price, L. R., Franklin, C., Salazar, M., Woolsey, M., Defronzo, R. A., Blangero, J., Glahn, D. C. & Fox, P. T., Jan 1 2019, In : Human Brain Mapping.

Research output: Contribution to journalArticle

Brain
Occipital Lobe
Caudate Nucleus
Genetic Structures
Temporal Lobe

A new risk to the axillary nerve during percutaneous proximal humeral plate fixation using the Synthes PHILOS aiming system

Dang, K. H., Ornell, S. S., Reyes, G., Hussey, M. & Dutta, A. K., Jan 1 2019, In : Journal of Shoulder and Elbow Surgery.

Research output: Contribution to journalArticle

Humerus
Confidence Intervals
Wounds and Injuries
Cadaver
Dissection
6 Citations (Scopus)

A niche-dependent myeloid transcriptome signature defines dormant myeloma cells

Khoo, W. H., Ledergor, G., Weiner, A., Roden, D. L., Terry, R. L., McDonald, M. M., Chai, R. C., De Veirman, K., Owen, K. L., Opperman, K. S., Vandyke, K., Clark, J. R., Seckinger, A., Kovacic, N., Nguyen, A., Mohanty, S. T., Pettitt, J. A., Xiao, Y., Corr, A. P., Seeliger, C. & 14 others, Novotny, M., Lasken, R. S., Nguyen, T. V., Oyajobi, B., Aftab, D., Swarbrick, A., Parker, B., Hewett, D. R., Hose, D., Vanderkerken, K., Zannettino, A. C. W., Amit, I., Phan, T. G. & Croucher, P. I., Jul 4 2019, In : Blood. 134, 1, p. 30-43 14 p.

Research output: Contribution to journalArticle

Transcriptome
Genes
Multiple Myeloma
Bearings (structural)
Disease Progression

Animal Models of Pneumococcal pneumonia

Borsa, N., Pasquale, M. D. & Restrepo, M., Aug 28 2019, In : International journal of molecular sciences. 20, 17

Research output: Contribution to journalReview article

Open Access
Pneumococcal Pneumonia
pneumonia
pathogenesis
animal models
infectious diseases

An Individualized Low-Intensity Walking Clinic Leads to Improvement in Frailty Characteristics in Older Veterans

Espinoza, S. E., Orsak, B., Wang, C. P., MacCarthy, D., Kellogg, D., Powers, B., Conde, A., Moris, M., Padala, P. R. & Padala, K. P., Jan 1 2019, In : The Journal of frailty & aging. 8, 4, p. 205-209 5 p.

Research output: Contribution to journalArticle

Veterans
Walking
Exercise
Geriatrics
Body Mass Index
1 Citation (Scopus)

An in-silico quality assurance study of contouring target volumes in thoracic tumors within a cooperative group setting

Elhalawani, H., Elgohari, B., Lin, T. A., Mohamed, A. S. R., Fitzgerald, T. J., Laurie, F., Ulin, K., Kalpathy-Cramer, J., Guerrero, T., Holliday, E. B., Russo, G., Patel, A., Jones, W., Walker, G. V., Awan, M., Choi, M., Dagan, R., Mahmoud, O., Shapiro, A., Kong, F. M. S. & 9 others, Gomez, D., Zeng, J., Decker, R., Spoelstra, F. O. B., Gaspar, L. E., Kachnic, L. A., Thomas, C. R., Okunieff, P. & Fuller, C. D., Feb 2019, In : Clinical and Translational Radiation Oncology. 15, p. 83-92 10 p.

Research output: Contribution to journalArticle

Open Access
Pancoast Syndrome
Four-Dimensional Computed Tomography
Computer Simulation
Thorax
Radiotherapy
1 Citation (Scopus)

A Non-canonical Role of YAP/TEAD Is Required for Activation of Estrogen-Regulated Enhancers in Breast Cancer

Zhu, C., Li, L., Zhang, Z., Bi, M., Wang, H., Su, W., Hernandez, K., Liu, P., Chen, J., Chen, M., Huang, T. H. M., Chen, L. & Liu, Z., Aug 22 2019, In : Molecular Cell. 75, 4, p. 791-806.e8

Research output: Contribution to journalArticle

Estrogens
Breast Neoplasms
Organ Size
Growth
Carcinogenesis

An Online System to Help With Mock Oral Examination Administration

Willis, R., Jan 1 2019, In : Journal of Surgical Education.

Research output: Contribution to journalArticle

Online Systems
Oral Diagnosis
Oral Administration
surgery
examination

Antagonism between the RNA-binding protein Musashi1 and miR-137 and its potential impact on neurogenesis and glioblastoma development

Velasco, M. X., Kosti, A., Guardia, G. D. A., Santos, M. C., Tegge, A., Qiao, M., Correa, B. R. S., Hernández, G., Cearley, E. K., Galante, P. A. F. & Penalva, L. O., Jan 1 2019, In : RNA. 27, 5, p. 768-782 15 p.

Research output: Contribution to journalArticle

Open Access
RNA-Binding Proteins
Neurogenesis
Glioblastoma
MicroRNAs
Glioma

Antifungal Resistance Testing and Implications for Management

Badali, H. & Wiederhold, N. P., Jan 1 2019, (Accepted/In press) In : Current Fungal Infection Reports.

Research output: Contribution to journalReview article

Mycoses
Antifungal Agents
Echinocandins
Azoles
Aspergillus fumigatus

Antigenic Site-Specific Competitive Antibody Responses to the Fusion Protein of Respiratory Syncytial Virus Were Associated With Viral Clearance in Hematopoietic Cell Transplantation Adults

Ye, X., Iwuchukwu, O. P., Avadhanula, V., Aideyan, L. O., McBride, T. J., Ferlic-Stark, L. L., Patel, K. D., Piedra, F. A., Shah, D. P., Chemaly, R. F. & Piedra, P. A., Jan 1 2019, In : Frontiers in immunology. 10, 1 p.

Research output: Contribution to journalArticle

Open Access
Respiratory Syncytial Viruses
Cell Transplantation
Antibody Formation
Antibodies
Neutralizing Antibodies

Antigen-specific CD4 T cell-derived gamma interferon is both necessary and sufficient for clearing chlamydia from the small intestine but not the large intestine

Lin, H., He, C., Koprivsek, J. J., Chen, J., Zhou, Z., Arulanandam, B., Xu, Z., Tang, L. & Zhong, G., Jan 1 2019, In : Infection and Immunity. 87, 6, e00055-19.

Research output: Contribution to journalArticle

CD4 Antigens
Chlamydia
Large Intestine
Interferon-gamma
Small Intestine

Antiphospholipid Antibodies: Cognitive and Motor Decline, Neuroimaging and Neuropathology

Arvanitakis, Z., Capuano, A. W., Brey, R. L., Fleischman, D. A., Arfanakis, K., Buchman, A. S., Schneider, J. A., Levine, S. R. & Bennett, D. A., Jan 1 2019, In : Neuroepidemiology.

Research output: Contribution to journalArticle

Antiphospholipid Antibodies
Cerebrovascular Disorders
Neuroimaging
Matrix Metalloproteinases
C-Reactive Protein
1 Citation (Scopus)
Pneumonia
Cohort Studies
Retrospective Studies
Odds Ratio
Confidence Intervals

Apego no resuelto desorganizado ajustado a un Factor de Psicopatología General asociado con conectividad funcional atípica de la amígdala en estado de reposo

Translated title of the contribution: Unresolved–disorganized attachment adjusted for a general psychopathology factor associated with atypical amygdala resting-state functional connectivityvan Hoof, M. J., Riem, M. M. E., Garrett, A. S., van der Wee, N. J. A., van IJzendoorn, M. H. & Vermeiren, R. R. J. M., Jan 1 2019, In : European Journal of Psychotraumatology. 10, 1, 1583525.

Research output: Contribution to journalArticle

Open Access
Amygdala
Psychopathology
Parietal Lobe
Gyrus Cinguli
Psychiatry
4 Citations (Scopus)

A phase II, multicenter, single-arm study of mipsagargin (G-202) as a second-line therapy following sorafenib for adult patients with progressive advanced hepatocellular carcinoma

Mahalingam, D., Peguero, J., Cen, P., Arora, S. P., Sarantopoulos, J., Rowe, J., Allgood, V., Tubb, B. & Campos, L., Jun 1 2019, In : Cancers. 11, 6, 833.

Research output: Contribution to journalArticle

Open Access
Hepatocellular Carcinoma
Disease-Free Survival
Disease Progression
Neoplasms
Magnetic Resonance Imaging
5 Citations (Scopus)

A phase II study of alisertib in children with recurrent/refractory solid tumors or leukemia: Children's Oncology Group Phase I and pilot Consortium (ADVL0921)

Mosse, Y. P., Fox, E., Teachey, D. T., Reid, J. M., Safgren, S. L., Carol, H., Lock, R. B., Houghton, P. J., Smith, M. A., Hall, D., Barkauskas, D. A., Krailo, M., Voss, S. D., Berg, S. L., Blaney, S. M. & Weigel, B. J., Jun 1 2019, In : Clinical Cancer Research. 25, 11, p. 3229-3238 10 p.

Research output: Contribution to journalArticle

Open Access
Leukemia
Aurora Kinase A
Neoplasms
Pharmacokinetics
Pharmacogenetics
2 Citations (Scopus)

Apn2 resolves blocked 3′ ends and suppresses Top1-induced mutagenesis at genomic rNMP sites

Li, F., Wang, Q., Seol, J. H., Che, J., Lu, X., Shim, E., Lee, S. & Niu, H., Jan 1 2019, In : Nature Structural and Molecular Biology.

Research output: Contribution to journalArticle

Ribonucleosides
Mutagenesis
Phosphates
Type I DNA Topoisomerase
Ribonucleases
2 Citations (Scopus)

A potential role for lysophosphatidylcholine in the delivery of long chain polyunsaturated fatty acids to the fetal circulation

Ferchaud-Roucher, V., Kramer, A., Silva, E., Pantham, P., Weintraub, S. E., Jansson, T. & Powell, T. L., Mar 1 2019, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1864, 3, p. 394-402 9 p.

Research output: Contribution to journalArticle

Lysophosphatidylcholines
Unsaturated Fatty Acids