5.29 - Trigeminal Mechanisms of Nociception: Peripheral and Brain Stem Organization

David A. Bereiter; Kenneth M. Hargreaves

doi:10.1016/B978-0-12-809324-5.24130-8

5.29 - Trigeminal Mechanisms of Nociception: Peripheral and Brain Stem Organization

David A. Bereiter, Kenneth M. Hargreaves

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

The trigeminal nerve (Vn) plays a unique role in protecting specialized sense organs of the head and oral cavity, such as the retina, from environmental challenges. Pain is the dominant sensation evoked by stimulation of dental pulp, cornea or dura, tissues supplied by almost exclusively by small diameter afferent fibers and that terminate as free nerve endings. Neuroimmune mechanisms act peripherally and centrally to modify craniofacial pain. Sex hormone status is a key factor in many craniofacial pain conditions which are often more prevalent in females than males.

Original language	English (US)
Title of host publication	The Senses
Subtitle of host publication	A Comprehensive Reference: Volume 1-7, Second Edition
Publisher	Elsevier
Pages	522-539
Number of pages	18
Volume	5
ISBN (Electronic)	9780128054093
ISBN (Print)	9780128054086
DOIs	https://doi.org/10.1016/B978-0-12-809324-5.24130-8
State	Published - Jan 1 2020

Keywords

Cornea
Craniofacial pain
Dental pain
Dura
Meningeal pain
Neuroimmune biomarkers
Ocular pain
Sex differences
Tooth pulp
Trigeminal brainstem
Trigeminal ganglion
Trigeminal nociceptors

ASJC Scopus subject areas

General Medicine
General Neuroscience

Access to Document

10.1016/B978-0-12-809324-5.24130-8

Cite this

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abstract = "The trigeminal nerve (Vn) plays a unique role in protecting specialized sense organs of the head and oral cavity, such as the retina, from environmental challenges. Pain is the dominant sensation evoked by stimulation of dental pulp, cornea or dura, tissues supplied by almost exclusively by small diameter afferent fibers and that terminate as free nerve endings. Neuroimmune mechanisms act peripherally and centrally to modify craniofacial pain. Sex hormone status is a key factor in many craniofacial pain conditions which are often more prevalent in females than males.",

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AU - Hargreaves, Kenneth M.

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AB - The trigeminal nerve (Vn) plays a unique role in protecting specialized sense organs of the head and oral cavity, such as the retina, from environmental challenges. Pain is the dominant sensation evoked by stimulation of dental pulp, cornea or dura, tissues supplied by almost exclusively by small diameter afferent fibers and that terminate as free nerve endings. Neuroimmune mechanisms act peripherally and centrally to modify craniofacial pain. Sex hormone status is a key factor in many craniofacial pain conditions which are often more prevalent in females than males.

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KW - Dental pain

KW - Dura

KW - Meningeal pain

KW - Neuroimmune biomarkers

KW - Ocular pain

KW - Sex differences

KW - Tooth pulp

KW - Trigeminal brainstem

KW - Trigeminal ganglion

KW - Trigeminal nociceptors

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5.29 - Trigeminal Mechanisms of Nociception: Peripheral and Brain Stem Organization

Abstract

Keywords

ASJC Scopus subject areas

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