Project: Research project

Project Details


The overall aim of the project is to evaluate the effects of psychiatric
treatments on the restoration of the capacity to work, and, more broadly,
to examine restoration of work function as an aspect of psychiatric
recovery. To date, we have published a comprehensive literature review
on work outcomes in psychiatry, compiled original databases with
unanalyzed and unpublished work outcome data from 18 treatment studies,
and published our analyses of the work outcome data from ten of the
studies (involving over 800 patients) on treatments of depression. The
proposed research continues our studies of recovery in depression, and
expands on our earlier work with new analyses in the areas of anxiety
disorders and schizophrenia. First, we propose to return to the
depression databases to examine functional impairment and recovery in the
homemaker role. Because of the Social Security Administration';s focus
on disability in the work-for-pay sector, our analyses to date completely
excluded depressed homemakers. These women, the only large group that
was excluded from our prior study, represent approximately one-third of
the females in the samples. Including an additional 25% or so of the
women in the samples who were working homemakers, we have information
about homemaker role functioning on approximately half of the depressed
women in these studies. Impairment in the homemaker domain has been
reported to be even more severe than at work, but controlled studies of
its treatment and course are lacking. The current proposal also includes
new studies. Following up on the suggestion in our literature review
that maintenance neuroleptic treatment of schizophrenia might be
associated with poorer vocational outcomes, we have compiled several data
sets from major clinical trials involving randomized assignment of
schizophrenic patients to more versus less neuroleptic, and now propose
to analyze them to test this specific hypothesis. The unifying thematic
link among these studies of different populations is that they bear on
work outcome as an effect of symptomatically-oriented treatments, and
more generally as an important component of psychiatric recovery.
Effective start/end date9/1/938/31/96


  • National Institutes of Health: $52,085.00


  • Medicine(all)


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