CAP - Consortium to Alleviate PTSD - STVHCS Data and Statistics Core

  • Peterson, Alan L (PI)

Project: Research project

Project Details


Data Management and Biostatistics Core
The objectives of the Data Core are to facilitate high-quality research by (1) organizing and maintaining the
Consortium, Repository, and project databases to maximize accessibility while maintaining strict
confidentiality; (2) developing and maintaining on-line data entry systems and other computer-based tools that
facilitate the entry, storage, manipulation, and retrieval of data generated by each project as well as project
management; (3) developing and applying modern statistical methods for the analysis of Consortium data (4)
providing methodological consultation in research design and biostatistical planning, (5) administering the
STRONG STAR Data Repository. Dr. Mintz has been Director of the STRONG STAR Data Core since the
inception of the Consortium. He will be joined by Dr. Ralitza Geugorguieva of the Yale School of Public
Health. Dr. Mintz, jointly appointed in Epidemiology/Biostatistics, also serves as Director of the Psychiatry
Department's Biostatistics Core. Dr. Mintz is a seasoned research methodologist and applied biostatistician,
with over four decades of experience collaborating in clinical research and directing data and statistics cores.
During his career at UCLA Psychiatry, he directed the Semel Institute Biostatistics Core and the Data and
Statistics Cores of the VISN 22 MIRECC and the UCLA Alzheimer's Center. Dr. Geugorguieva brings
expertise in methodological development of models for longitudinal data, assessment of risk, and the
application of innovative statistical approaches to clinical trials data including mixed and mixture models and
tree-based methods. The STRONG STAR Data Core supports all of the clinical projects for the STRONG
STAR Consortium with full-featured Internet-based data entry and project management systems. In addition to
ensuring high-quality data by providing features such as double data entry, field and logical validation, flagging
of discrepancies for later adjudication, scoring algorithms, and control of participant entry in multiple projects
and duplicate records, the Core has provided projects with tools for matters such as adverse events and DSMB
reporting, complex randomization schemes, barcode scanning, scheduling, online PDFs of source documents,
multi-speed online video streaming for training, and other innovations. A current focus of the Core is the
development of research applications for mobile devices including smartphones and tablets. Dr. Mintz consults
regularly with Consortium investigators on the planning and analysis of their research projects, including
development and clarification of research aims and formation of testable hypotheses, study design, sample size
planning and statistical analysis. During the past year, he and the Core participated in the planning and analysis
of data for more than 30 poster and panel presentations at national conferences.
Effective start/end date9/1/148/31/19


  • National Institutes of Health


  • Medicine(all)


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