AUDITORY EVOKED POTENTIALS

  • Dobie, Robert A (PI)

Project: Research project

Project Details

Description

The primary long-term objective of this research program continues to be
the development of more efficient and accurate auditory evoked potential
(AEP) tests, especially for threshold estimation in children and others who
can't cooperate for conventional audiometry. Most of the analytic
techniques under study are not unique to AEPs, however. Thus, this work is
broadly relevant to evoked potentials, regardless of sensory modality,k and
to signal processing for other types of evoked response (e.g. acoustic
reflex or evoked oto-acoustic emissions). In a series of experiments using normal-hearing subjects and patients with
hearing loss, scalp-recorded AEPs will be obtained and analyzed to answer
the following questions:
1.Can coherence analysis be optimized by smoothing across data segments or
frequency?
2.Will weighted averaging and/or Wiener filtering improve AEP and coherence
estimates?
3.In normal subjects, is objective response detection using coherence
analysis more accurate than human observers' judgments in detecting low-
level AEPs?
4.In patients with hearing loss, are threshold estimates from coherence
analysis more accurate than estimates from observer inspection of AEPs?
Will high-pass masking improve low-frequency threshold estimates?
5.Can a single AEP (to a pseudo-random noise stimulus) be used to estimate
responses to different spectral regions of the stimulus?
6.Can AEPs to complex AM tones be used to estimate system response to
different modulation frequencies?
7.Will chloral hydrate sedation differentially affect AEP response to low
modulation frequencies?
StatusFinished
Effective start/end date7/1/866/30/00

Funding

  • National Institutes of Health: $175,840.00
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health: $173,839.00
  • National Institutes of Health: $181,027.00
  • National Institutes of Health: $162,574.00
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health: $162,171.00
  • National Institutes of Health
  • National Institutes of Health

ASJC

  • Medicine(all)
  • Neuroscience(all)

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