Yui-wing F Lam

  • 2201 Citations
  • 24 h-Index
1982 …2016
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Research Output 1986 2016

2016

Clinically significant interactions with antidepressants

Lam, Y. F., Jan 1 2016, Applied Clinical Pharmacokinetics and Pharmacodynamics of Psychopharmacological Agents. Springer International Publishing, p. 451-469 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Antidepressive Agents
Cytochrome P-450 Enzyme System
Drug Interactions
Isoenzymes
Serotonin Uptake Inhibitors
10 Citations (Scopus)

Metformin for reducing racial/ethnic difference in prostate cancer incidence for men with type II diabetes

Wang, C., Lehman, D. M., Lam, Y. F., Kuhn, J. G., Mahalingam, D., Weitman, S. D., Lorenzo, C., Downs, J. R., Stuart, E. A., Hernandez, J., Thompson, I. M. & Ramirez, A. G., Oct 1 2016, In : Cancer Prevention Research. 9, 10, p. 779-787 9 p.

Research output: Contribution to journalArticle

Metformin
Type 2 Diabetes Mellitus
Prostatic Neoplasms
Incidence
Hispanic Americans
8 Citations (Scopus)

Pharmacokinetics of Phenobarbital in Microenema Via Macy Catheter Versus Suppository

Lam, Y. F., Lam, A. & Macy, B., Jun 1 2016, In : Journal of Pain and Symptom Management. 51, 6, p. 994-1001 8 p.

Research output: Contribution to journalArticle

Suppositories
Phenobarbital
Catheters
Pharmacokinetics
Tablets
2014

Scientific challenges and implementation barriers to translation of pharmacogenomics in clinical practice

Lam, Y. F., Jan 1 2014, Omics in Clinical Practice: Genomics, Pharmacogenomics, Proteomics, and Transcriptomics in Clinical Research. Apple Academic Press, p. 95-133 39 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Drug therapy
Pharmacogenetics
Polymorphism
Health care
Metabolism
2013
6 Citations (Scopus)

Pharmacogenomics

Lam, Y. F. & Cavallari, L. H., 2013, Elsevier Inc.

Research output: Book/ReportBook

Pharmacogenetics
Pharmaceutical Preparations
Medical Economics
Industry
Therapeutics
1 Citation (Scopus)

Pharmacogenomics in Psychiatric Disorders

Lam, Y. F., Fukui, N., Sugai, T., Watanabe, J., Watanabe, Y., Suzuki, Y. & Someya, T., 2013, Pharmacogenomics. Elsevier Inc., p. 191-223 33 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Pharmacogenetics
Psychiatry
Psychotropic Drugs
Pharmaceutical Preparations
Receptor, Serotonin, 5-HT2C

Preface

Lam, Y. F. & Cavallari, L. H., 2013, In : Unknown Journal.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Principles of Pharmacogenomics: Pharmacokinetic, Pharmacodynamic, and Clinical Implications

Lam, Y. F. & Cavallari, L. H., 2013, Pharmacogenomics. Elsevier Inc., p. 1-44 44 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Pharmacogenetics
Pharmacokinetics
Pharmaceutical Preparations
Drug Prescriptions
Human Genome

The Role of Pharmacogenomics in Diabetes, HIV Infection, and Pain Management

Aquilante, C. L. & Lam, Y. F., 2013, Pharmacogenomics. Elsevier Inc., p. 247-271 25 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Pharmacogenetics
Pain Management
Hypoglycemic Agents
HIV Infections
Type 2 Diabetes Mellitus
1 Citation (Scopus)

Translating Pharmacogenomic Research to Therapeutic Potentials

Lam, Y. F., 2013, Pharmacogenomics. Elsevier Inc., p. 45-61 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Therapeutic Human Experimentation
Precision Medicine
Pharmacogenetics
Technology
Drug Therapy
2012
1 Citation (Scopus)
Precision Medicine
Pharmacogenetics
Health Education
Ecosystem
Drug Therapy
2009
1 Citation (Scopus)

Effects of rifampin on the disposition of gepirone ER and its metabolites

Lam, Y. F., Ereshefsky, L., Port, A., Timmer, C. J. & Dogterom, P., 2009, In : Open Drug Metabolism Journal. 3, p. 1-7 7 p.

Research output: Contribution to journalArticle

Rifampin
Cytochrome P-450 CYP3A
Area Under Curve
Hydrocortisone
gepirone
2008
92 Citations (Scopus)

The use of individually tailored environmental supports to improve medication adherence and outcomes in schizophrenia

Velligan, D. I., Diamond, P. M., Mintz, J., Maples, N. J., Li, X., Zeber, J., Ereshefsky, L., Lam, Y. F., Castillo, D. & Miller, A. L., May 2008, In : Schizophrenia Bulletin. 34, 3, p. 483-493 11 p.

Research output: Contribution to journalArticle

Medication Adherence
Schizophrenia
House Calls
Therapeutics
Grooming
2007
162 Citations (Scopus)

Relationships among subjective and objective measures of adherence to oral antipsychotic medications

Velligan, D. I., Wang, M., Diamond, P., Glahn, D. C., Castillo, D., Bendle, S., Lam, Y. F., Ereshefsky, L. & Miller, A. L., Sep 2007, In : Psychiatric Services. 58, 9, p. 1187-1192 6 p.

Research output: Contribution to journalArticle

Antipsychotic Agents
medication
physician
Physicians
Self Report
2006

A review of Chinese botanical product-drug interactions

Lam, Y. F. & Ou, M., Jan 1 2006, Herbal Supplements-Drug Interactions: Scientific and Regulatory Perspectives. CRC Press, p. 123-146 24 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Drug Interactions
Pharmaceutical Preparations
Literature
4 Citations (Scopus)

Botanical products-drug interactions: Focus on garlic, ginkgo and ginseng

Lam, Y. F. & Ernst, E., Jan 1 2006, Herbal Supplements-Drug Interactions: Scientific and Regulatory Perspectives. CRC Press, p. 107-121 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Ginkgo biloba
Panax
Garlic
Drug Interactions
Delivery of Health Care
204 Citations (Scopus)

Defining and assessing adherence to oral antipsychotics: A review of the literature

Velligan, D. I., Lam, Y. F., Glahn, D. C., Barrett, J. A., Maples, N. J., Ereshefsky, L. & Miller, A. L., Oct 2006, In : Schizophrenia Bulletin. 32, 4, p. 724-742 19 p.

Research output: Contribution to journalArticle

Antipsychotic Agents
Consensus
Terminology
MEDLINE
Self Report
2 Citations (Scopus)

Drug interactions with botanical products

Lam, Y. F., Huang, S. M. & Hall, S. D., Jan 1 2006, Herbal Supplements-Drug Interactions: Scientific and Regulatory Perspectives. CRC Press, p. 25-47 23 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Prescription Drugs
Drug Interactions
Dietary Supplements
Prescriptions
Pharmacokinetics
2 Citations (Scopus)

Herbal supplements-drug interactions: Scientific and regulatory perspectives

Lam, Y. F., Huang, S. M. & Hall, S. D., Jan 1 2006, CRC Press. 358 p.

Research output: Book/ReportBook

Herb-Drug Interactions
Drug Interactions
Industry
12 Citations (Scopus)

Insulin absorption: a major factor in apparent insulin resistance and the control of type 2 diabetes mellitus

Friedberg, S. J., Lam, Y. F., Blum, J. J. & Gregerman, R. I., May 2006, In : Metabolism: Clinical and Experimental. 55, 5, p. 614-619 6 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Insulin Resistance
Insulin
Short-Acting Insulin
Isophane Insulin
1 Citation (Scopus)

Preface

Lam, Y. F., Huang, S. M. & Hall, S. D., Jan 1 2006, Herbal Supplements-Drug Interactions: Scientific and Regulatory Perspectives. CRC Press, p. iii-iv

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

2005
9 Citations (Scopus)
Isradipine
Cocaine
Diagnostic and Statistical Manual of Mental Disorders
Cocaine-Related Disorders
Investigational Therapies
2004
4 Citations (Scopus)

Relative Bioavailability of an Extemporaneous Ondansetron 4-mg Capsule Formulation versus Solution

Lam, Y. F., Javors, M. A., Ait-Daoud, N., Roache, J. D. & Johnson, B. A., Apr 2004, In : Pharmacotherapy. 24, 4, p. 477-481 5 p.

Research output: Contribution to journalArticle

Ondansetron
Biological Availability
Capsules
Pharmacokinetics
Research
2003
49 Citations (Scopus)

Correlation of cytochrome P450 (CYP) 1A2 activity using caffeine phenotyping and olanzapine disposition in healthy volunteers.

Shirley, K. L., Hon, Y. Y., Penzak, S. R., Lam, Y. F., Spratlin, V. & Jann, M. W., May 2003, In : Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 28, 5, p. 961-966 6 p.

Research output: Contribution to journalArticle

olanzapine
Cytochrome P-450 CYP1A2
Caffeine
Healthy Volunteers
Saliva
21 Citations (Scopus)

Influence of hydroxypropyl methylcellulose polymer on in vitro and in vivo performance of controlled release tablets containing alprazolam

Mahaguna, V., Talbert, R., Peters, J. I., Adams, S. G., Reynolds, T. D., Lam, Y. F. & Williams, R. O., Nov 2003, In : European Journal of Pharmaceutics and Biopharmaceutics. 56, 3, p. 461-468 8 p.

Research output: Contribution to journalArticle

Alprazolam
Tablets
Polymers
Humidity
Pharmacokinetics
92 Citations (Scopus)

Perspectives on medication adherence and atypical antipsychotic medications

Velligan, D. I., Lam, Y. F., Ereshefsky, L. & Miller, A. L., May 1 2003, In : Psychiatric Services. 54, 5, p. 665-667 3 p.

Research output: Contribution to journalArticle

schizophrenia
medication
87 Citations (Scopus)

Pharmacokinetic and Pharmacodynamic Interactions of Oral Midazolam with Ketoconazole, Fluoxetine, Fluvoxamine, and Nefazodone

Lam, Y. F., Alfaro, C. L., Ereshefsky, L. & Miller, M., Nov 2003, In : Journal of Clinical Pharmacology. 43, 11, p. 1274-1282 9 p.

Research output: Contribution to journalArticle

Fluvoxamine
Ketoconazole
Fluoxetine
Midazolam
Pharmacokinetics
2002
66 Citations (Scopus)

CYP2D6 inhibition by selective serotonin reuptake inhibitors: Analysis of achievable steady-state plasma concentrations and the effect of ultrarapid metabolism at CYP2D6

Lam, Y. F., Gaedigk, A., Ereshefsky, L., Alfaro, C. L. & Simpson, J., 2002, In : Pharmacotherapy. 22, 8, p. 1001-1006 6 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP2D6
Serotonin Uptake Inhibitors
Paroxetine
Fluoxetine
Fluvoxamine
2001
37 Citations (Scopus)

Branded versus generic clozapine: Bioavailability comparison and interchangeability issues

Lam, Y. F., Ereshefsky, L., Toney, G. B. & Gonzales, C., 2001, In : Journal of Clinical Psychiatry. 62, SUPPL. 5, p. 18-22 5 p.

Research output: Contribution to journalArticle

Clozapine
Biological Availability
Therapeutic Equivalency
Pharmacokinetics
Pharmaceutical Preparations
Dextromethorphan
Ketoconazole
Midazolam
Cytochrome P-450 CYP3A
Urine Specimen Collection
13 Citations (Scopus)

Lack of CYP3A4 inhibition by grapefruit juice and ketoconazole upon clozapine administration in vivo

Lane, H. Y., Chiu, C. C., Kazmi, Y., Desai, H., Lam, Y. F., Jann, M. W. & Chang, W. H., 2001, In : Drug Metabolism and Drug Interactions. 18, 3-4, p. 263-278 16 p.

Research output: Contribution to journalArticle

Citrus paradisi
Cytochrome P-450 CYP3A
Ketoconazole
Clozapine
Isoenzymes
2000
11 Citations (Scopus)

Clinical pharmacology of dopamine agonists

Lam, Y. F., 2000, In : Pharmacotherapy. 20, 1 II

Research output: Contribution to journalArticle

Clinical Pharmacology
Dopamine Agonists
Levodopa
Dopamine D2 Receptors
Dyskinesias
106 Citations (Scopus)
Dextrorphan
Sertraline
Cytochrome P-450 CYP2D6
Paroxetine
Dextromethorphan
1999
73 Citations (Scopus)

CYP2D6 status of extensive metabolizers after multiple-dose fluoxetine, fluvoxamine, paroxetine, or sertraline

Alfaro, C. L., Lam, Y. F., Simpson, J. & Ereshefsky, L., Apr 1999, In : Journal of Clinical Psychopharmacology. 19, 2, p. 155-163 9 p.

Research output: Contribution to journalArticle

Dextrorphan
Dextromethorphan
Fluvoxamine
Sertraline
Cytochrome P-450 CYP2D6
5 Citations (Scopus)

In vivo inhibition of midazolam disposition by ketoconazole and fluoxetine, and comparison to in vitro prediction

Lam, Y. F., Ereshefsky, L., Alfaro, C. & Miller, M., 1999, In : Clinical Pharmacology and Therapeutics. 65, 2, p. 143 1 p.

Research output: Contribution to journalArticle

Ketoconazole
Fluoxetine
Midazolam
Area Under Curve
Healthy Volunteers
1998
59 Citations (Scopus)

Reversible metabolism of clozapine and clozapine N-oxide in schizophrenic patients

Chang, W. H., Lin, S. K., Lane, H. Y., Wei, F. C., Hu, W. H., Lam, Y. F. & Jann, M. W., Jul 1998, In : Progress in Neuro-Psychopharmacology and Biological Psychiatry. 22, 5, p. 723-739 17 p.

Research output: Contribution to journalArticle

Clozapine
Pharmacokinetics
clozapine N-oxide
1997
7 Citations (Scopus)

Plasma alpha-one acid glycoprotein and haloperidol concentrations in schizophrenic patients

Jann, M. W., Crabtree, B. L., Pitts, W. M., Lam, Y. F. & Carter, J. G., Jun 1997, In : Neuropsychobiology. 36, 1, p. 32-36 5 p.

Research output: Contribution to journalArticle

Haloperidol
Brief Psychiatric Rating Scale
Glycoproteins
Acids
Placebos
121 Citations (Scopus)

Principles of drug administration in renal insufficiency

Lam, Y. F., Banerji, S., Hatfield, C. & Talbert, R., 1997, In : Clinical Pharmacokinetics. 32, 1, p. 30-57 28 p.

Research output: Contribution to journalArticle

Renal Insufficiency
Pharmaceutical Preparations
Kidney
Dialysis
Costs and Cost Analysis
12 Citations (Scopus)

Review: Pharmacokinetics and pharmacodynamics of the taxanes

Lam, Y. F., Chan, J. C. Y. & Kuhn, J. G., 1997, In : Journal of Oncology Pharmacy Practice. 3, 2, p. 76-93 18 p.

Research output: Contribution to journalArticle

docetaxel
Taxoids
Paclitaxel
Pharmacokinetics
MEDLINE
8 Citations (Scopus)

Treating depression: Potential drug interactions

Ereshefsky, L., Alfaro, C. L. & Lam, Y. F., Apr 1997, In : Psychiatric Annals. 27, 4, p. 244-258 15 p.

Research output: Contribution to journalArticle

Drug Interactions
1996
1 Citation (Scopus)

Disposition of remoxipride in Chinese schizophrenic patients

Lin, S. K., Chang, W. H., Chien, C. P., Lam, Y. F. & Jann, M. W., 1996, In : International Journal of Clinical Pharmacology and Therapeutics. 34, 1, p. 17-20 4 p.

Research output: Contribution to journalArticle

Remoxipride
Area Under Curve
Half-Life
Blood
Sampling
6 Citations (Scopus)

Lack of pharmacokinetic interaction between buspirone and haloperidol in patients with schizophrenia

Huang, H. F., Jann, M. W., Wei, F. C., Chang, T. P., Chen, J. S., Juang, D. J., Lin, S. K., Lam, Y. F., Chien, C. P. & Chang, W. H., Oct 1996, In : Journal of Clinical Pharmacology. 36, 10, p. 963-969 7 p.

Research output: Contribution to journalArticle

Buspirone
Haloperidol
Schizophrenia
Pharmacokinetics
Half-Life
58 Citations (Scopus)

Serotonin selective reuptake inhibitor drug interactions and the cytochrome P450 system

Ereshefsky, L., Riesenman, C. & Lam, Y. F., 1996, In : Journal of Clinical Psychiatry. 57, SUPPL. 8, p. 17-25 9 p.

Research output: Contribution to journalArticle

Serotonin Uptake Inhibitors
Drug Interactions
Cytochrome P-450 Enzyme System
Isoenzymes
Cytochrome P-450 CYP2D6
1995
137 Citations (Scopus)

Antidepressant drug interactions and the cytochrome P450 system. The role of cytochrome P450 2D6

Ereshefsky, L., Riesenmann, C. & Lam, Y. F., 1995, In : Clinical Pharmacokinetics. 29, 4 SUPPL. 1, p. 10-19 10 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP2D6
Desipramine
Drug Interactions
Cytochrome P-450 Enzyme System
Antidepressive Agents
57 Citations (Scopus)

Disposition and covalent binding of ibuprofen and its acyl glucuronide in the elderly

Castillo, M., Lam, Y. F., Dooley, M. A., Stahl, E. & Smith, P. C., Jun 1995, In : Clinical Pharmacology and Therapeutics. 57, 6, p. 636-644 9 p.

Research output: Contribution to journalArticle

Ibuprofen
Glucuronides
Blood Proteins
ibuprofen acyl glucuronide
Anti-Inflammatory Agents
3 Citations (Scopus)

Disposition of haloperidol and reduced haloperidol plasma levels after single dose haloperidol decanoate administration

Chang, W. H., Juang, D. J., Lin, S. K., Huang, J. D., Lam, Y. F., Jann, M. W. & Chien, C. P., 1995, In : Human Psychopharmacology. 10, 1, p. 47-51 5 p.

Research output: Contribution to journalArticle

Haloperidol
Injections
Half-Life
Pharmacokinetics
High Pressure Liquid Chromatography
28 Citations (Scopus)

Intra- and interethnic variability in reduced haloperidol to haloperidol ratios

Lam, Y. F., Jann, M. W., Chang, W. H., Yu, H. S., Lin, S. K., Chen, H. & Davis, C. M., 1995, In : Journal of Clinical Pharmacology. 35, 2, p. 128-136 9 p.

Research output: Contribution to journalArticle

Haloperidol
Ethnic Groups
4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol
Pharmaceutical Preparations
3 Citations (Scopus)

Roxithromycin disposition in patients on continuous ambulatory peritoneal dialysis

Lam, Y. F., Flaherty, J. F., Yumena, L., Schoenfeld, P. Y. & Gambertoglio, J. G., Jul 1995, In : Journal of Antimicrobial Chemotherapy. 36, 1, p. 157-163 7 p.

Research output: Contribution to journalArticle

Roxithromycin
Dialysis
Continuous Ambulatory Peritoneal Dialysis
Dose
Clearance
1994
36 Citations (Scopus)

Disposition of clozapine and desmethylclozapine in schizophrenic patients

Lin, S. K., Chang, W. H., Chung, M. C., Lam, Y. F. & Jann, M. W., 1994, In : Journal of Clinical Pharmacology. 34, 4, p. 318-324 7 p.

Research output: Contribution to journalArticle

Clozapine
Area Under Curve
Half-Life
Pharmacokinetics
2 Citations (Scopus)

Formation of reduced haloperidol after intramuscular haloperidol administration in schizophrenic patients

Jann, M. W., Huang, H. F., Lin, S. K., Juang, D. J., Lam, Y. F. & Chang, W. H., 1994, In : Drug Investigation. 7, 1, p. 18-25 8 p.

Research output: Contribution to journalArticle

Haloperidol
Homovanillic Acid
Intramuscular Injections
4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol
Half-Life