• 2028 Citations
  • 22 h-Index
19942019
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  • 1 Similar Profiles
Vaccinia virus Medicine & Life Sciences
Poxviridae Medicine & Life Sciences
Interleukin-18 Medicine & Life Sciences
Virion Medicine & Life Sciences
Proteins Medicine & Life Sciences
virion Agriculture & Biology
Epitopes Medicine & Life Sciences
Molluscum contagiosum virus Medicine & Life Sciences

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Projects 2003 2019

Poxviridae
Interleukin-18
Immune Evasion
Vaccines
Monkeypox virus

Molecular Mechanism of Poxvirus Host Range Genes

Xiang, Y.

National Institutes of Health

9/20/078/31/10

Project: Research projectExploratory/Developmental Grants

Poxviridae
Host Specificity
Ankyrin Repeat
Mitogen-Activated Protein Kinase 7
Orthopoxvirus

Poxvirus immune modulators and the host Immune system

Xiang, Y.

National Institutes of Health

4/1/033/31/06

Project: Research projectCareer Transition Award

Poxviridae
Interleukin-18
Immune System
Molluscum contagiosum virus
Interleukin-18 Receptors

Research Output 1994 2018

  • 2028 Citations
  • 22 h-Index
  • 54 Article
1 Citations

A paralogous pair of mammalian host restriction factors form a critical host barrier against poxvirus infection

Meng, X., Zhang, F., Yan, B., Si, C., Honda, H., Nagamachi, A., Sun, L. Z. & Xiang, Y., Feb 1 2018, In : PLoS Pathogens. 14, 2, e1006884.

Research output: Contribution to journalArticle

Poxviridae Infections
Poxviridae
Vaccinia virus
Interferons
Host Specificity

Characterization of murine antibody responses to vaccinia virus envelope protein A14 reveals an immunodominant antigen lacking of effective neutralization targets

Meng, X., Kaever, T., Yan, B., Traktman, P., Zajonc, D. M., Peters, B., Crotty, S. & Xiang, Y., May 1 2018, In : Virology. 518, p. 284-292 9 p.

Research output: Contribution to journalArticle

Viral Envelope Proteins
Immunodominant Epitopes
Vaccinia virus
Antibody Formation
Smallpox Vaccine

Structure-function characterization of three human antibodies targeting the vaccinia virus adhesion molecule D8

Matho, M. H., Schlossman, A., Gilchuk, I. M., Miller, G., Mikulski, Z., Hupfer, M., Wang, J., Bitra, A., Meng, X., Xiang, Y., Kaever, T., Doukov, T., Ley, K., Crotty, S., Peters, B., Hsieh-Wilson, L. C., Crowe, J. E. & Zajonc, D. M., Jan 1 2018, In : Journal of Biological Chemistry. 293, 1, p. 390-401 12 p.

Research output: Contribution to journalArticle

Chondroitin Sulfates
Vaccinia virus
Viruses
Adhesion
Molecules

Structure of a lipid-bound viral membrane assembly protein reveals a modality for enclosing the lipid bilayer

Pathak, P. K., Peng, S., Meng, X., Han, Y., Zhang, B., Zhang, F., Xiang, Y. & Deng, J., Jul 3 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 27, p. 7028-7032 5 p.

Research output: Contribution to journalArticle

Viral Matrix Proteins
Virus Assembly
Lipid Bilayers
Lipids
Membranes

Development of an animal model of progressive vaccinia in nu/nu mice and the use of bioluminescence imaging for assessment of the efficacy of monoclonal antibodies against vaccinial B5 and L1 proteins

Zaitseva, M., Thomas, A., Meseda, C. A., Cheung, C. Y. K., Diaz, C. G., Xiang, Y., Crotty, S. & Golding, H., Aug 1 2017, In : Antiviral Research. 144, p. 8-20 13 p.

Research output: Contribution to journalArticle

Vaccinia
Vaccinia virus
Animal Models
Monoclonal Antibodies
Nude Mice

Press/Media