Yan Xiang — Scholars @ UT Health San Antonio

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1 Similar Profiles

Vaccinia virus Medicine & Life Sciences

Poxviridae Medicine & Life Sciences

Interleukin-18 Medicine & Life Sciences

Virion Medicine & Life Sciences

Proteins Medicine & Life Sciences

virion Agriculture & Biology

Epitopes Medicine & Life Sciences

Molluscum contagiosum virus Medicine & Life Sciences

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Projects 2003 2019

1 Not started
1 Active
2 Finished

Immune modulation mechanism mediated by poxvirus IL-18 binding protein

Xiang, Y.

National Institutes of Health

9/24/08 → 3/31/19

Project: Research project › Research Project

Poxviridae

Interleukin-18

Immune Evasion

Vaccines

Monkeypox virus

Non-vesicular lipid transport by poxvirus A6 protein

Xiang, Y.

Project: Research project

Molecular Mechanism of Poxvirus Host Range Genes

Xiang, Y.

National Institutes of Health

9/20/07 → 8/31/10

Project: Research project › Exploratory/Developmental Grants

Poxviridae

Host Specificity

Ankyrin Repeat

Mitogen-Activated Protein Kinase 7

Orthopoxvirus

Poxvirus immune modulators and the host Immune system

Xiang, Y.

National Institutes of Health

4/1/03 → 3/31/06

Project: Research project › Career Transition Award

Poxviridae

Interleukin-18

Immune System

Molluscum contagiosum virus

Interleukin-18 Receptors

Research Output 1994 2018

2028 Citations
22 h-Index
54 Article

1 Citations

A paralogous pair of mammalian host restriction factors form a critical host barrier against poxvirus infection

Meng, X., Zhang, F., Yan, B., Si, C., Honda, H., Nagamachi, A., Sun, L. Z. & Xiang, Y., Feb 1 2018, In : PLoS Pathogens. 14, 2, e1006884.

Research output: Contribution to journal › Article

Poxviridae Infections

Poxviridae

Vaccinia virus

Interferons

Host Specificity

Characterization of murine antibody responses to vaccinia virus envelope protein A14 reveals an immunodominant antigen lacking of effective neutralization targets

Meng, X., Kaever, T., Yan, B., Traktman, P., Zajonc, D. M., Peters, B., Crotty, S. & Xiang, Y., May 1 2018, In : Virology. 518, p. 284-292 9 p.

Research output: Contribution to journal › Article

Viral Envelope Proteins

Immunodominant Epitopes

Vaccinia virus

Antibody Formation

Smallpox Vaccine

Structure-function characterization of three human antibodies targeting the vaccinia virus adhesion molecule D8

Matho, M. H., Schlossman, A., Gilchuk, I. M., Miller, G., Mikulski, Z., Hupfer, M., Wang, J., Bitra, A., Meng, X., Xiang, Y., Kaever, T., Doukov, T., Ley, K., Crotty, S., Peters, B., Hsieh-Wilson, L. C., Crowe, J. E. & Zajonc, D. M., Jan 1 2018, In : Journal of Biological Chemistry. 293, 1, p. 390-401 12 p.

Research output: Contribution to journal › Article

Chondroitin Sulfates

Vaccinia virus

Viruses

Adhesion

Molecules

Structure of a lipid-bound viral membrane assembly protein reveals a modality for enclosing the lipid bilayer

Pathak, P. K., Peng, S., Meng, X., Han, Y., Zhang, B., Zhang, F., Xiang, Y. & Deng, J., Jul 3 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 27, p. 7028-7032 5 p.

Research output: Contribution to journal › Article

Viral Matrix Proteins

Virus Assembly

Lipid Bilayers

Lipids

Membranes

Development of an animal model of progressive vaccinia in nu/nu mice and the use of bioluminescence imaging for assessment of the efficacy of monoclonal antibodies against vaccinial B5 and L1 proteins

Zaitseva, M., Thomas, A., Meseda, C. A., Cheung, C. Y. K., Diaz, C. G., Xiang, Y., Crotty, S. & Golding, H., Aug 1 2017, In : Antiviral Research. 144, p. 8-20 13 p.

Research output: Contribution to journal › Article

Vaccinia

Vaccinia virus

Animal Models

Monoclonal Antibodies

Nude Mice