Yan Xiang

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Vaccinia virus Medicine & Life Sciences

Poxviridae Medicine & Life Sciences

Interleukin-18 Medicine & Life Sciences

Virion Medicine & Life Sciences

Proteins Medicine & Life Sciences

Orthopoxvirus Medicine & Life Sciences

virion Agriculture & Biology

Epitopes Medicine & Life Sciences

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Projects 2003 2019

1 Not started
3 Finished

Non-vesicular lipid transport by poxvirus A6 protein

Xiang, Y.

Project: Research project

Immune modulation mechanism mediated by poxvirus IL-18 binding protein

Xiang, Y.

National Institutes of Health

9/24/08 → 3/31/19

Project: Research project

Poxviridae

Interleukin-18

Immune Evasion

Vaccines

Monkeypox virus

Molecular Mechanism of Poxvirus Host Range Genes

Xiang, Y.

National Institutes of Health

9/20/07 → 8/31/10

Project: Research project

Poxviridae

Host Specificity

Ankyrin Repeat

Mitogen-Activated Protein Kinase 7

Orthopoxvirus

Poxvirus immune modulators and the host Immune system

Xiang, Y.

National Institutes of Health

4/1/03 → 3/31/06

Project: Research project

Poxviridae

Interleukin-18

Immune System

Molluscum contagiosum virus

Interleukin-18 Receptors

Research Output 1994 2019

2139 Citations
23 h-Index
56 Article

Identification of CP77 as the third orthopoxvirus SAMD9 and SAMD9L inhibitor with unique specificity for a rodent SAMD9L

Zhang, F., Meng, X., Townsend, M. B., Satheshkumar, P. S. & Xiang, Y., Jan 1 2019, In : Journal of Virology. 93, 12, e0022519.

Research output: Contribution to journal › Article

Orthopoxvirus

Chinese hamsters

Cricetulus

Rodentia

rodents

2 Citations (Scopus)

RNA granules associated with SAMD9-mediated poxvirus restriction are similar to antiviral granules in composition but do not require TIA1 for poxvirus restriction

Meng, X. & Xiang, Y., Mar 1 2019, In : Virology. 529, p. 16-22 7 p.

Research output: Contribution to journal › Article

Poxviridae

Antiviral Agents

Viral DNA

RNA

Viral Structures

6 Citations (Scopus)

A paralogous pair of mammalian host restriction factors form a critical host barrier against poxvirus infection

Meng, X., Zhang, F., Yan, B., Si, C., Honda, H., Nagamachi, A., Sun, L. & Xiang, Y., Feb 1 2018, In : PLoS Pathogens. 14, 2, e1006884.

Research output: Contribution to journal › Article

Poxviridae Infections

Poxviridae

Vaccinia virus

Interferons

Host Specificity

Characterization of murine antibody responses to vaccinia virus envelope protein A14 reveals an immunodominant antigen lacking of effective neutralization targets

Meng, X., Kaever, T., Yan, B., Traktman, P., Zajonc, D. M., Peters, B., Crotty, S. & Xiang, Y., May 1 2018, In : Virology. 518, p. 284-292 9 p.

Research output: Contribution to journal › Article

Viral Envelope Proteins

Immunodominant Epitopes

Vaccinia virus

Antibody Formation

Smallpox Vaccine

Structure-function characterization of three human antibodies targeting the vaccinia virus adhesion molecule D8

Matho, M. H., Schlossman, A., Gilchuk, I. M., Miller, G., Mikulski, Z., Hupfer, M., Wang, J., Bitra, A., Meng, X., Xiang, Y., Kaever, T., Doukov, T., Ley, K., Crotty, S., Peters, B., Hsieh-Wilson, L. C., Crowe, J. E. & Zajonc, D. M., Jan 1 2018, In : Journal of Biological Chemistry. 293, 1, p. 390-401 12 p.

Research output: Contribution to journal › Article

Chondroitin Sulfates

Vaccinia virus

Viruses

Adhesion

Molecules