Xueqiu Jian

2024

Admixture mapping of cognitive function in diverse Hispanic and Latino adults: Results from the Hispanic Community Health Study/Study of Latinos

Xia, R., Jian, X., Rodrigue, A. L., Bressler, J., Boerwinkle, E., Cui, B., Daviglus, M. L., DeCarli, C., Gallo, L. C., Glahn, D. C., Knowles, E. E. M., Moon, J. Y., Mosley, T. H., Satizabal, C. L., Sofer, T., Tarraf, W., Testai, F., Blangero, J., Seshadri, S. & González, H. M. & 1 others, Fornage, M., Sep 2024, In: Alzheimer's and Dementia. 20, 9, p. 6070-6081 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

A genome-wide association meta-analysis of all-cause and vascular dementia

The Mega Vascular Cognitive Impairment and Dementia (MEGAVCID) consortium, Sep 2024, In: Alzheimer's and Dementia. 20, 9, p. 5973-5995 23 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Genetic variants for head size share genes and pathways with cancer

The Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium & The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium, May 21 2024, In: Cell Reports Medicine. 5, 5, 101529.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Human whole-exome genotype data for Alzheimer’s disease

Leung, Y. Y., Naj, A. C., Chou, Y. F., Valladares, O., Schmidt, M., Hamilton-Nelson, K., Wheeler, N., Lin, H., Gangadharan, P., Qu, L., Clark, K., Kuzma, A. B., Lee, W. P., Cantwell, L., Nicaretta, H., van der Lee, S., English, A., Kalra, D., Muzny, D. & Skinner, E. & 121 others, Doddapeneni, H., Dinh, H., Hu, J., Santibanez, J., Jayaseelan, J., Worley, K., Gibbs, R. A., Lee, S., Dugan-Perez, S., Korchina, V., Nasser, W., Liu, X., Han, Y., Zhu, Y., Liu, Y., Khan, Z., Zhu, C., Sun, F. J., Jun, G. R., Chung, J., Farrell, J., Zhang, X., Banks, E., Gupta, N., Gabriel, S., Butkiewicz, M., Benchek, P., Smieszek, S., Song, Y., Vardarajan, B., Reitz, C., Reyes-Dumeyer, D., Tosto, G., De Jager, P. L., Barral, S., Ma, Y., Beiser, A., Liu, C. T., Dupuis, J., Lunetta, K., Cupples, L. A., Choi, S. H., Chen, Y., Mez, J., Vanderspek, A., Ikram, M. A., Ahmad, S., Faber, K., Foroud, T., Mlynarski, E., Schmidt, H., Schmidt, R., Kunkle, B., Rajabli, F., Beecham, G., Vance, J. M., Adams, L. D., Cuccaro, M., Mena, P., Booth, B. M., Renton, A., Goate, A., Marcora, E., Stine, A., Feolo, M., Launer, L. J., Koboldt, D. C., Wilson, R. K., van Duijn, C., Amin, N., Kapoor, M., Salerno, W., Bennett, D. A., Xia, L. C., Malamon, J., Mosley, T. H., Satizabal, C., Jan Bressler, B., Jian, X., Nato, A. Q., Horimoto, A. R., Wang, B., Psaty, B., Witten, D., Tsuang, D., Blue, E., Wijsman, E., Sohi, H., Nguyen, H., Bis, J. C., Rice, K., Brown, L., Dorschner, M., Saad, M., Navas, P., Nafikov, R., Thornton, T., Day, T., Haut, J., Sha, J., Zhang, N., Iqbal, T., Zhao, Y., Below, J. E., Larson, D. E., Appelbaum, E., Waligorski, J., Antonacci-Fulton, L., Fulton, R. S., Haines, J., Farrer, L., Seshadri, S., Brkanac, Z., Cruchaga, C., Pericak-Vance, M., Mayeux, R. P., Bush, W. S., Destefano, A., Martin, E., Schellenberg, G. D. & Wang, L. S., Dec 2024, In: Nature communications. 15, 1, 684.

Research output: Contribution to journal › Article › peer-review

Open Access

The African Initiative for Bioinformatics Online Training in Neurodegenerative Diseases (AI-BOND): Investing in the next generation of African neuroscientists

Fongang, B., Ayele, B. A., Wadop, Y. N., Epenge, E., Nkouonlack, C. D., Njamnshi, W. Y., Jian, X., Sargurupremraj, M., Djotsa, A. B. S. N., Seke Etet, P. F., Bernal, R., Atangana, A., Cavazos, J. E., Himali, J. J., Fonteh, A. N., Maestre, G., Njamnshi, A. K. & Seshadri, S., Oct 1 2024, In: Alzheimer's and Dementia: Translational Research and Clinical Interventions. 10, 4, e70002.

Research output: Contribution to journal › Article › peer-review

Open Access

2022

Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate

Mishra, A., Duplaà, C., Vojinovic, D., Suzuki, H., Sargurupremraj, M., Zilhão, N. R., Li, S., Bartz, T. M., Jian, X., Zhao, W., Hofer, E., Wittfeld, K., Harris, S. E., Van Der Auwera-Palitschka, S., Luciano, M., Bis, J. C., Adams, H. H. H., Satizabal, C. L., Gottesman, R. F. & Gampawar, P. G. & 47 others, Bülow, R., Weiss, S., Yu, M., Bastin, M. E., Lopez, O. L., Vernooij, M. W., Beiser, A. S., Völker, U., Kacprowski, T., Soumare, A., Smith, J. A., Knopman, D. S., Morris, Z., Zhu, Y., Rotter, J. I., Dufouil, C., Valdes Hernández, M., Muñoz Maniega, S., Lathrop, M., Boerwinkle, E., Schmidt, R., Ihara, M., Mazoyer, B., Yang, Q., Joutel, A., Tournier-Lasserve, E., Launer, L. J., Deary, I. J., Mosley, T. H., Amouyel, P., Decarli, C. S., Psaty, B. M., Tzourio, C., Kardia, S. L. R., Grabe, H. J., Teumer, A., Van Duijn, C. M., Schmidt, H., Wardlaw, J. M., Ikram, M. A., Fornage, M., Gudnason, V., Seshadri, S., Matthews, P. M., Longstreth, W. T., Couffinhal, T. & Debette, S., Jun 1 2022, In: Brain. 145, 6, p. 1992-2007 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

Multi-phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations

Temprano-Sagrera, G., Sitlani, C. M., Bone, W. P., Martin-Bornez, M., Voight, B. F., Morrison, A. C., Damrauer, S. M., de Vries, P. S., Smith, N. L., Sabater-Lleal, M., Dehghan, A., Heath, A. S., Morrison, A. C., Reiner, A. P., Johnson, A., Richmond, A., Peters, A., van Hylckama Vlieg, A., McKnight, B. & Psaty, B. M. & 363 others, Hayward, C., Ward-Caviness, C., O’Donnell, C., Chasman, D., Strachan, D. P., Tregouet, D. A., Mook-Kanamori, D., Gill, D., Thibord, F., Asselbergs, F. W., Leebeek, F. W. G., Rosendaal, F. R., Davies, G., Homuth, G., Temprano, G., Campbell, H., Taylor, H. A., Bressler, J., Huffman, J. E., Rotter, J. I., Yao, J., Wilson, J. F., Bis, J. C., Hahn, J. M., Desch, K. C., Wiggins, K. L., Raffield, L. M., Bielak, L. F., Yanek, L. R., Kleber, M. E., Mueller, M., Kavousi, M., Mangino, M., Liu, M., Brown, M. R., Conomos, M. P., Jhun, M. A., Chen, M. H., de Maat, M. P. M., Pankratz, N., Smith, N. L., Peyser, P. A., Elliot, P., Wei, P., Wild, P. S., Morange, P. E., van der Harst, P., Yang, Q., Le, N. Q., Marioni, R., Li, R., Damrauer, S. M., Cox, S. R., Trompet, S., Felix, S. B., Völker, U., Tang, W., Koenig, W., Jukema, J. W., Guo, X., Lindstrom, S., Wang, L., Smith, E. N., Gordon, W., van Hylckama Vlieg, A., de Andrade, M., Brody, J. A., Pattee, J. W., Haessler, J., Brumpton, B. M., Suchon, P., Chen, M. H., Turman, C., Germain, M., Wiggins, K. L., MacDonald, J., Braekkan, S. K., Armasu, S. M., Pankratz, N., Jackson, R. D., Nielsen, J. B., Giulianini, F., Puurunen, M. K., Ibrahim, M., Heckbert, S. R., Bammler, T. K., Frazer, K. A., McCauley, B. M., Taylor, K., Pankow, J. S., Reiner, A. P., Gabrielsen, M. E., Deleuze, J. F., O’Donnell, C. J., Kim, J., McKnight, B., Kraft, P., Hansen, J. B., Rosendaal, F. R., Heit, J. A., Psaty, B. M., Tang, W., Kooperberg, C., Hveem, K., Ridker, P. M., Morange, P. E., Johnson, A. D., Kabrhel, C., Trégouët, D. A., Smith, N. L., Malik, R., Chauhan, G., Traylor, M., Sargurupremraj, M., Okada, Y., Mishra, A., Rutten-Jacobs, L., Giese, A. K., van der Laan, S. W., Gretarsdottir, S., Anderson, C. D., Chong, M., Adams, H. H. H., Ago, T., Almgren, P., Amouyel, P., Ay, H., Bartz, T. M., Benavente, O. R., Bevan, S., Boncoraglio, G. B., Brown, R. D., Butterworth, A. S., Carrera, C., Carty, C. L., Chen, W. M., Cole, J. W., Correa, A., Cotlarciuc, I., Cruchaga, C., Danesh, J., de Bakker, P. I. W., DeStefano, A. L., den Hoed, M., Duan, Q., Engelter, S. T., Falcone, G. J., Gottesman, R. F., Grewal, R. P., Gudnason, V., Gustafsson, S., Haessler, J., Harris, T. B., Hassan, A., Havulinna, A. S., Heckbert, S. R., Holliday, E. G., Howard, G., Hsu, F. C., Hyacinth, H. I., Arfan Ikram, M., Ingelsson, E., Irvin, M. R., Jian, X., Jiménez-Conde, J., Johnson, J. A., Jukema, J. W., Kanai, M., Keene, K. L., Kissela, B. M., Kleindorfer, D. O., Kooperberg, C., Kubo, M., Lange, L. A., Langefeld, C. D., Langenberg, C., Launer, L. J., Lee, J. M., Lemmens, R., Leys, D., Lewis, C. M., Lin, W. Y., Lindgren, A. G., Lorentzen, E., Magnusson, P. K., Maguire, J., Manichaikul, A., McArdle, P. F., Meschia, J. F., Mitchell, B. D., Mosley, T. H., Nalls, M. A., Ninomiya, T., O’Donnell, M. J., Psaty, B. M., Pulit, S. L., Rannikmäe, K., Reiner, A. P., Rexrode, K. M., Rice, K., Rich, S. S., Ridker, P. M., Rost, N. S., Rothwell, P. M., Rotter, J. I., Rundek, T., Sacco, R. L., Sakaue, S., Sale, M. M., Salomaa, V., Sapkota, B. R., Schmidt, R., Schmidt, C. O., Schminke, U., Sharma, P., Slowik, A., Sudlow, C. L. M., Tanislav, C., Tatlisumak, T., Taylor, K. D., Thijs, V. N. S., Thorleifsson, G., Thorsteinsdottir, U., Tiedt, S., Trompet, S., Tzourio, C., van Duijn, C. M., Walters, M., Wareham, N. J., Wassertheil-Smoller, S., Wilson, J. G., Wiggins, K. L., Yang, Q., Yusuf, S., Amin, N., Aparicio, H. S., Arnett, D. K., Attia, J., Beiser, A. S., Berr, C., Buring, J. E., Bustamante, M., Caso, V., Cheng, Y. C., Hoan Choi, S., Chowhan, A., Cullell, N., Dartigues, J. F., Delavaran, H., Delgado, P., Dörr, M., Engström, G., Ford, I., Gurpreet, W. S., Hamsten, A., Heitsch, L., Hozawa, A., Ibanez, L., Ilinca, A., Ingelsson, M., Iwasaki, M., Jackson, R. D., Jood, K., Jousilahti, P., Kaffashian, S., Kalra, L., Kamouchi, M., Kitazono, T., Kjartansson, O., Kloss, M., Koudstaal, P. J., Krupinski, J., Labovitz, D. L., Laurie, C. C., Levi, C. R., Li, L., Lind, L., Lindgren, C. M., Lioutas, V., Mei Liu, Y., Lopez, O. L., Makoto, H., Martinez-Majander, N., Matsuda, K., Minegishi, N., Montaner, J., Morris, A. P., Muiño, E., Müller-Nurasyid, M., Norrving, B., Ogishima, S., Parati, E. A., Reddy Peddareddygari, L., Pedersen, N. L., Pera, J., Perola, M., Pezzini, A., Pileggi, S., Rabionet, R., Riba-Llena, I., Ribasés, M., Romero, J. R., Roquer, J., Rudd, A. G., Sarin, A. P., Sarju, R., Sarnowski, C., Sasaki, M., Satizabal, C. L., Satoh, M., Sattar, N., Sawada, N., Sibolt, G., Sigurdsson, Á., Smith, A., Sobue, K., Soriano-Tárraga, C., Stanne, T., Colin Stine, O., Stott, D. J., Strauch, K., Takai, T., Tanaka, H., Tanno, K., Teumer, A., Tomppo, L., Torres-Aguila, N. P., Touze, E., Tsugane, S., Uitterlinden, A. G., Valdimarsson, E. M., van der Lee, S. J., Völzke, H., Wakai, K., Weir, D., Williams, S. R., Wolfe, C. D. A., Wong, Q., Xu, H., Yamaji, T., Sanghera, D. K., Melander, O., Jern, C., Strbian, D., Fernandez-Cadenas, I., Longstreth, W. T., Rolfs, A., Hata, J., Woo, D., Rosand, J., Pare, G., Hopewell, J. C., Saleheen, D., Stefansson, K., Worrall, B. B., Kittner, S. J., Seshadri, S., Fornage, M., Markus, H. S., Howson, J. M. M., Kamatani, Y., Debette, S. & Dichgans, M., Jun 1 2022, In: Journal of Thrombosis and Haemostasis. 20, 6, p. 1331-1349 19 p.

Research output: Contribution to journal › Article › peer-review

Open Access

15 Scopus citations

New insights into the genetic etiology of Alzheimer’s disease and related dementias

EADB, GR@ACE, DEGESCO, EADI, GERAD, Demgene, FinnGen, ADGC & CHARGE, Apr 1 2022, In: Nature Genetics. 54, 4, p. 412-436 25 p.

Research output: Contribution to journal › Article › peer-review

Open Access

987 Scopus citations

Stroke genetics informs drug discovery and risk prediction across ancestries

The COMPASS Consortium, The INVENT Consortium, The Dutch Parelsnoer Initiative (PSI) Cerebrovascular Disease Study Group, The Estonian Biobank, The PRECISEQ Consortium, The FinnGen Consortium, The NINDS Stroke Genetics Network (SiGN), The MEGASTROKE Consortium, The SIREN Consortium, The China Kadoorie Biobank Collaborative Group, the VA Million Veteran Program, The International Stroke Genetics Consortium (ISGC), The Biobank Japan, The CHARGE Consortium, The GIGASTROKE Consortium, Regeneron Genetics Center, The ODYSSEY Study, HUNT All-In Stroke, The SICFAIL Study & The Generacion Study & 6 others, The Copenhagen City Heart Study, The SMART Study, Clinical Research Collaboration for Stroke in Korea (CRCS-K) and Korea Biobank Array (KBA) Project, Helsinki Stroke Project, Follow-up Studies & EPIC-CVD, Nov 3 2022, In: Nature. 611, 7934, p. 115-123 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

220 Scopus citations

2021

Association of low-frequency and rare coding variants with information processing speed

Bressler, J., Davies, G., Smith, A. V., Saba, Y., Bis, J. C., Jian, X., Hayward, C., Yanek, L., Smith, J. A., Mirza, S. S., Wang, R., Adams, H. H. H., Becker, D., Boerwinkle, E., Campbell, A., Cox, S. R., Eiriksdottir, G., Fawns-Ritchie, C., Gottesman, R. F. & Grove, M. L. & 35 others, Guo, X., Hofer, E., Kardia, S. L. R., Knol, M. J., Koini, M., Lopez, O. L., Marioni, R. E., Nyquist, P., Pattie, A., Polasek, O., Porteous, D. J., Rudan, I., Satizabal, C. L., Schmidt, H., Schmidt, R., Sidney, S., Simino, J., Smith, B. H., Turner, S. T., van der Lee, S. J., Ware, E. B., Whitmer, R. A., Yaffe, K., Yang, Q., Zhao, W., Gudnason, V., Launer, L. J., Fitzpatrick, A. L., Psaty, B. M., Fornage, M., Arfan Ikram, M., van Duijn, C. M., Seshadri, S., Mosley, T. H. & Deary, I. J., Dec 2021, In: Translational psychiatry. 11, 1, 613.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores

EADB contributors, The GR@ACE study group, DEGESCO consortium, IGAP (ADGC, CHARGE, EADI, GERAD) & PGC-ALZ consortia, Dec 1 2021, In: Nature communications. 12, 1, 3417.

Research output: Contribution to journal › Article › peer-review

Open Access

161 Scopus citations

Multiomics integrative analysis identifies APOE allele-specific blood biomarkers associated to Alzheimer’s disease etiopathogenesis

Madrid, L., Moreno-Grau, S., Ahmad, S., González-Pérez, A., de Rojas, I., Xia, R., Adami, P. V. M., García-González, P., Kleineidam, L., Yang, Q., Damotte, V., Bisl, J. C., Noguera-Perea, F., Bellenguez, C., Jian, X., Marín-Muñoz, J., Grenier-Boley, B., Orellana, A., Ikram, M. A. & Amouye, P. & 16 others, Satizabal, C. L., Real, L. M., Antúnez-Almagro, C., DeStefano, A., Cabrera-Socorro, A., Sims, R., Duijn, C. M. V., Boerwinkle, E., Ramírez, A., Fornage, M., Lambert, J. C., Williams, J., Seshadri, S., Ried, J. S., Ruiz, A. & Saez, M. E., Apr 15 2021, In: Aging. 13, 7, p. 9277-9329 53 p.

Research output: Contribution to journal › Article › peer-review

Open Access

20 Scopus citations

2020

Cerebral small vessel disease genomics and its implications across the lifespan

International Headache Genomics Consortium (IHGC) & International Network against Thrombosis (INVENT) Consortium, Dec 2020, In: Nature communications. 11, 1, 6285.

Research output: Contribution to journal › Article › peer-review

Open Access

118 Scopus citations

Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults

Hofer, E., Roshchupkin, G. V., Adams, H. H. H., Knol, M. J., Lin, H., Li, S., Zare, H., Ahmad, S., Armstrong, N. J., Satizabal, C. L., Bernard, M., Bis, J. C., Gillespie, N. A., Luciano, M., Mishra, A., Scholz, M., Teumer, A., Xia, R., Jian, X. & Mosley, T. H. & 363 others, Saba, Y., Pirpamer, L., Seiler, S., Becker, J. T., Carmichael, O., Rotter, J. I., Psaty, B. M., Lopez, O. L., Amin, N., van der Lee, S. J., Yang, Q., Himali, J. J., Maillard, P., Beiser, A. S., Decarli, C., Karama, S., Lewis, L., Harris, M., Bastin, M. E., Deary, I. J., Witte, A. V., Beyer, F., Loeffler, M., Mather, K. A., Schofield, P. R., Thalamuthu, A., Kwok, J. B., Wright, M. J., Ames, D., Trollor, J., Jiang, J., Brodaty, H., Wen, W., Vernooij, M. W., Hofman, A., Uitterlinden, A. G., Niessen, W. J., Wittfeld, K., Bülow, R., Völker, U., Pausova, Z., Pike, G. B., Maingault, S., Crivello, F., Tzourio, C., Amouyel, P., Mazoyer, B., Neale, M. C., Franz, C. E., Lyons, M. J., Panizzon, M. S., Andreassen, O. A., Dale, A. M., Logue, M., Grasby, K. L., Jahanshad, N., Painter, J. N., Colodro-Conde, L., Bralten, J., Hibar, D. P., Lind, P. A., Pizzagalli, F., Stein, J. L., Thompson, P. M., Medland, S. E., Sachdev, P. S., Kremen, W. S., Wardlaw, J. M., Villringer, A., van Duijn, C. M., Grabe, H. J., Longstreth, W. T., Fornage, M., Paus, T., Debette, S., Ikram, M. A., Schmidt, H., Schmidt, R., Seshadri, S., Ching, C. R. K., McMahon, M. A. B., Shatokhina, N., Zsembik, L. C. P., Agartz, I., Alhusaini, S., Almeida, M. A. A., Alnæs, D., Amlien, I. K., Andersson, M., Ard, T., Ashley-Koch, A., Brouwer, R. M., Buimer, E. E. L., Bürger, C., Cannon, D. M., Chakravarty, M., Chen, Q., Cheung, J. W., Couvy-Duchesne, B., Dalvie, S., de Araujo, T. K., de Zubicaray, G. I., de Zwarte, S. M. C., Braber, A. D., Doan, N. T., Dohm, K., Ehrlich, S., Engelbrecht, H. R., Erk, S., Fan, C. C., Fedko, I. O., Foley, S. F., Ford, J. M., Fukunaga, M., Garrett, M. E., Ge, T., Giddaluru, S., Goldman, A. L., Groenewold, N. A., Grotegerd, D., Gurholt, T. P., Gutman, B. A., Hansell, N. K., Harris, M. A., Harrison, M. B., Haswell, C. C., Hauser, M., Herms, S., Heslenfeld, D. J., Ho, N. F., Hoehn, D., Hoffmann, P., Holleran, L., Hoogman, M., Hottenga, J. J., Ikeda, M., Janowitz, D., Jansen, I. E., Jia, T., Jockwitz, C., Kanai, R., Kasperaviciute, D., Kaufmann, T., Kelly, S., Kikuchi, M., Klein, M., Knapp, M., Knodt, A. R., Krämer, B., Lam, M., Lancaster, T. M., Lee, P. H., Lett, T. A., Lopes-Cendes, I., Macciardi, F., Marquand, A. F., Mathias, S. R., Melzer, T. R., Milaneschi, Y., Mirza-Schreiber, N., Moreira, J. C. V., Mühleisen, T. W., Müller-Myhsok, B., Najt, P., Nakahara, S., Nho, K., Olde Loohuis, L. M., Orfanos, D. P., Pearson, J. F., Pitcher, T. L., Pütz, B., Ragothaman, A., Rashid, F. M., Redlich, R., Reinbold, C. S., Repple, J., Richard, G., Riedel, B. C., Risacher, S. L., Rocha, C. S., Mota, N. R., Salminen, L., Saremi, A., Saykin, A. J., Schlag, F., Schmaal, L., Secolin, R., Shapland, C. Y., Shen, L., Shin, J., Shumskaya, E., Sønderby, I. E., Sprooten, E., Strike, L. T., Tansey, K. E., Thomopoulos, S. I., Tordesillas-Gutiérrez, D., Turner, J. A., Uhlmann, A., Vallerga, C. L., Meer, D. V. D., van Donkelaar, M. M. J., Eijk, L. V., van Erp, T. G. M., van Haren, N. E. M., Rooij, D. V., Tol, M. J. V., Veldink, J. H., Verhoef, E., Walton, E., Wang, M., Wang, Y., Westlye, L. T., Whelan, C. D., Witt, S. H., Wolf, C., Wolfers, T., Yasuda, C. L., Zaremba, D., Zhang, Z., Zhu, A. H., Zwiers, M. P., Artiges, E., Assareh, A. A., Ayesa-Arriola, R., Belger, A., Brandt, C. L., Brown, G. G., Cichon, S., Curran, J. E., Davies, G. E., Degenhardt, F., Dietsche, B., Djurovic, S., Doherty, C. P., Espiritu, R., Garijo, D., Gil, Y., Gowland, P. A., Green, R. C., Häusler, A. N., Heindel, W., Ho, B. C., Hoffmann, W. U., Holsboer, F., Homuth, G., Hosten, N., Jack, C. R., Jang, M., Jansen, A., Kolskår, K., Koops, S., Krug, A., Lim, K. O., Luykx, J. J., Mathalon, D. H., Mattay, V. S., Matthews, S., Van Son, J. M., McEwen, S. C., Melle, I., Morris, D. W., Mueller, B. A., Nauck, M., Nordvik, J. E., Nöthen, M. M., O’leary, D. S., Opel, N., Martinot, M. L. P., Preda, A., Quinlan, E. B., Ratnakar, V., Reppermund, S., Steen, V. M., Torres, F. R., Veltman, D. J., Voyvodic, J. T., Whelan, R., White, T., Yamamori, H., Alvim, M. K. M., Anderson, T. J., Arias-Vasquez, A., Baune, B. T., Blangero, J. C., Boomsma, D. I., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Bustillo, J. R., Cahn, W., Calhoun, V., Caseras, X., Caspers, S., Cavalleri, G. L., Cendes, F., Corvin, A., Crespo-Facorro, B., Dalrymple-Alford, J. C., Dannlowski, U., de Geus, E. J. C., Delanty, N., Depondt, C., Desrivières, S., Donohoe, G., Espeseth, T., Fernández, G., Fisher, S. E., Flor, H., Forstner, A. J., Francks, C., Franke, B., Glahn, D. C., Gollub, R. L., Gruber, O., Håberg, A. K., Hariri, A. R., Hartman, C. A., Hashimoto, R., Heinz, A., Hillegers, M. H. J., Hoekstra, P. J., Holmes, A. J., Hong, L. E., Hopkins, W. D., Hulshoff Pol, H. E., Jernigan, T. L., Jönsson, E. G., Kahn, R. S., Kennedy, M. A., Kircher, T. T. J., Kochunov, P., Le Hellard, S., Martin, N. G., Martinot, J. L., McDonald, C., McMahon, K. L., Meyer-Lindenberg, A., Morey, R. A., Nyberg, L., Oosterlaan, J., Ophoff, R. A., Penninx, B. W. J. H., Polderman, T. J. C., Posthuma, D., Rietschel, M., Roffman, J. L., Rowland, L. M., Sämann, P. G., Schumann, G., Sim, K., Sisodiya, S. M., Smoller, J. W., Sommer, I. E., Pourcain, B. S., Toga, A. W., Van der Wee, N. J. A., Van’T Ent, D., Völzke, H., Walter, H., Weber, B., Weinberger, D. R. & Zhou, J., Dec 1 2020, In: Nature communications. 11, 1, 4796.

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Open Access

68 Scopus citations

Genome-wide association study of cognitive function in diverse Hispanics/Latinos: results from the Hispanic Community Health Study/Study of Latinos

Jian, X., Sofer, T., Tarraf, W., Bressler, J., Faul, J. D., Zhao, W., Ratliff, S. M., Lamar, M., Launer, L. J., Laurie, C. C., Schneiderman, N., Weir, D. R., Wright, C. B., Yaffe, K., Zeng, D., DeCarli, C., Mosley, T. H., Smith, J. A., González, H. M. & Fornage, M., Dec 1 2020, In: Translational psychiatry. 10, 1, 245.

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Open Access

13 Scopus citations

Global and regional development of the human cerebral cortex: Molecular architecture and occupational aptitudes

the ENIGMA Consortium & the neuroCHARGE Working Group, 2020, In: Cerebral Cortex. 30, 7, p. 4121-4139 19 p.

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Open Access

16 Scopus citations

Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation

Alzheimer’s Disease Sequencing Project, Aug 1 2020, In: Molecular psychiatry. 25, 8, p. 1859-1875 17 p.

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Open Access

165 Scopus citations

2019

A prospective study of serum metabolites and risk of ischemic stroke

Sun, D., Tiedt, S., Yu, B., Jian, X., Gottesman, R. F., Mosley, T. H., Boerwinkle, E., Dichgans, M. & Fornage, M., Apr 16 2019, In: Neurology. 92, 16, p. E1890-E1898

Research output: Contribution to journal › Article › peer-review

Open Access

61 Scopus citations

A rare missense variant of CASP7 is associated with familial late-onset Alzheimer's disease

Alzheimer’s Disease Sequencing Project, Mar 2019, In: Alzheimer's and Dementia. 15, 3, p. 441-452 12 p.

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Open Access

32 Scopus citations

Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects

Mishra, A., Chauhan, G., Violleau, M. H., Vojinovic, D., Jian, X., Bis, J. C., Li, S., Saba, Y., Grenier-Boley, B., Yang, Q., Bartz, T. M., Hofer, E., Soumaré, A., Peng, F., Duperron, M. G., Foglio, M., Mosley, T. H., Schmidt, R., Psaty, B. M. & Launer, L. J. & 14 others, Boerwinkle, E., Zhu, Y., Mazoyer, B., Lathrop, M., Bellenguez, C., Van Duijn, C. M., Arfan Ikram, M., Schmidt, H., Longstreth, W. T., Fornage, M., Seshadri, S., Joutel, A., Tzourio, C. & Debette, S., Apr 1 2019, In: Brain. 142, 4, p. 1009-1023 15 p.

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39 Scopus citations

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting

Stroke Genetics Network (SiGN), International Stroke Genetics Consortium (ISGC), METASTROKE, Alzheimer’s Disease Genetics Consortium (ADGC) & Neurology Working Group of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, Jan 29 2019, In: Neurology. 92, 5, p. E486-E503

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

Genetic architecture of subcortical brain structures in 38,851 individuals

Satizabal, C. L., Adams, H. H. H., Hibar, D. P., White, C. C., Knol, M. J., Stein, J. L., Scholz, M., Sargurupremraj, M., Jahanshad, N., Roshchupkin, G. V., Smith, A. V., Bis, J. C., Jian, X., Luciano, M., Hofer, E., Teumer, A., van der Lee, S. J., Yang, J., Yanek, L. R. & Lee, T. V. & 269 others, Li, S., Hu, Y., Koh, J. Y., Eicher, J. D., Desrivières, S., Arias-Vasquez, A., Chauhan, G., Athanasiu, L., Rentería, M. E., Kim, S., Hoehn, D., Armstrong, N. J., Chen, Q., Holmes, A. J., den Braber, A., Kloszewska, I., Andersson, M., Espeseth, T., Grimm, O., Abramovic, L., Alhusaini, S., Milaneschi, Y., Papmeyer, M., Axelsson, T., Ehrlich, S., Roiz-Santiañez, R., Kraemer, B., Håberg, A. K., Jones, H. J., Pike, G. B., Stein, D. J., Stevens, A., Bralten, J., Vernooij, M. W., Harris, T. B., Filippi, I., Witte, A. V., Guadalupe, T., Wittfeld, K., Mosley, T. H., Becker, J. T., Doan, N. T., Hagenaars, S. P., Saba, Y., Cuellar-Partida, G., Amin, N., Hilal, S., Nho, K., Mirza-Schreiber, N., Arfanakis, K., Becker, D. M., Ames, D., Goldman, A. L., Lee, P. H., Boomsma, D. I., Lovestone, S., Giddaluru, S., Le Hellard, S., Mattheisen, M., Bohlken, M. M., Kasperaviciute, D., Schmaal, L., Lawrie, S. M., Agartz, I., Walton, E., Tordesillas-Gutierrez, D., Davies, G. E., Shin, J., Ipser, J. C., Vinke, L. N., Hoogman, M., Jia, T., Burkhardt, R., Klein, M., Crivello, F., Janowitz, D., Carmichael, O., Haukvik, U. K., Aribisala, B. S., Schmidt, H., Strike, L. T., Cheng, C. Y., Risacher, S. L., Pütz, B., Fleischman, D. A., Assareh, A. A., Mattay, V. S., Buckner, R. L., Mecocci, P., Dale, A. M., Cichon, S., Boks, M. P., Matarin, M., Penninx, B. W. J. H., Calhoun, V. D., Chakravarty, M. M., Marquand, A. F., Macare, C., Kharabian Masouleh, S., Oosterlaan, J., Amouyel, P., Hegenscheid, K., Rotter, J. I., Schork, A. J., Liewald, D. C. M., de Zubicaray, G. I., Wong, T. Y., Shen, L., Sämann, P. G., Brodaty, H., Roffman, J. L., de Geus, E. J. C., Tsolaki, M., Erk, S., van Eijk, K. R., Cavalleri, G. L., van der Wee, N. J. A., McIntosh, A. M., Gollub, R. L., Bulayeva, K. B., Bernard, M., Richards, J. S., Himali, J. J., Loeffler, M., Rommelse, N., Hoffmann, W., Westlye, L. T., Valdés Hernández, M. C., Hansell, N. K., van Erp, T. G. M., Wolf, C., Kwok, J. B. J., Vellas, B., Heinz, A., Olde Loohuis, L. M., Delanty, N., Ho, B. C., Ching, C. R. K., Shumskaya, E., Singh, B., Hofman, A., van der Meer, D., Homuth, G., Psaty, B. M., Bastin, M. E., Montgomery, G. W., Foroud, T. M., Reppermund, S., Hottenga, J. J., Simmons, A., Meyer-Lindenberg, A., Cahn, W., Whelan, C. D., van Donkelaar, M. M. J., Yang, Q., Hosten, N., Green, R. C., Thalamuthu, A., Mohnke, S., Hulshoff Pol, H. E., Lin, H., Jack, C. R., Schofield, P. R., Mühleisen, T. W., Maillard, P., Potkin, S. G., Wen, W., Fletcher, E., Toga, A. W., Gruber, O., Huentelman, M., Davey Smith, G., Launer, L. J., Nyberg, L., Jönsson, E. G., Crespo-Facorro, B., Koen, N., Greve, D. N., Uitterlinden, A. G., Weinberger, D. R., Steen, V. M., Fedko, I. O., Groenewold, N. A., Niessen, W. J., Toro, R., Tzourio, C., Longstreth, W. T., Ikram, M. K., Smoller, J. W., van Tol, M. J., Sussmann, J. E., Paus, T., Lemaître, H., Schroeter, M. L., Mazoyer, B., Andreassen, O. A., Holsboer, F., Depondt, C., Veltman, D. J., Turner, J. A., Pausova, Z., Schumann, G., van Rooij, D., Djurovic, S., Deary, I. J., McMahon, K. L., Müller-Myhsok, B., Brouwer, R. M., Soininen, H., Pandolfo, M., Wassink, T. H., Cheung, J. W., Wolfers, T., Martinot, J. L., Zwiers, M. P., Nauck, M., Melle, I., Martin, N. G., Kanai, R., Westman, E., Kahn, R. S., Sisodiya, S. M., White, T., Saremi, A., van Bokhoven, H., Brunner, H. G., Völzke, H., Wright, M. J., van ‘t Ent, D., Nöthen, M. M., Ophoff, R. A., Buitelaar, J. K., Fernández, G., Sachdev, P. S., Rietschel, M., van Haren, N. E. M., Fisher, S. E., Beiser, A. S., Francks, C., Saykin, A. J., Mather, K. A., Romanczuk-Seiferth, N., Hartman, C. A., DeStefano, A. L., Heslenfeld, D. J., Weiner, M. W., Walter, H., Hoekstra, P. J., Nyquist, P. A., Franke, B., Bennett, D. A., Grabe, H. J., Johnson, A. D., Chen, C., van Duijn, C. M., Lopez, O. L., Fornage, M., Wardlaw, J. M., Schmidt, R., DeCarli, C., De Jager, P. L., Villringer, A., Debette, S., Gudnason, V., Medland, S. E., Shulman, J. M., Thompson, P. M., Seshadri, S. & Ikram, M. A., Nov 1 2019, In: Nature Genetics. 51, 11, p. 1624-1636 13 p.

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175 Scopus citations

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Alzheimer Disease Genetics Consortium (ADGC), The European Alzheimer’s Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE), & Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES), Mar 1 2019, In: Nature Genetics. 51, 3, p. 414-430 17 p.

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1816 Scopus citations

Serum magnesium and calcium levels in relation to ischemic stroke: Mendelian randomization study

Larsson, S. C., Traylor, M., Burgess, S., Boncoraglio, G. B., Jern, C., Michaëlsson, K., Markus, H. S., Malik, R., Chauhan, G., Sargurupremraj, M., Okada, Y., Mishra, A., Rutten-Jacobs, L., Giese, A. K., Van Der Laan, S. W., Gretarsdottir, S., Anderson, C. D., Chong, M., Adams, H. H. H. & Ago, T. & 237 others, Almgren, P., Amouyel, P., Ay, H., Bartz, R. M., Benavente, O. R., Bevan, S., Brown, R. D., Butterworth, A. S., Carrera, C., Carty, C. L., Chasman, D. I., Chen, W. M., Cole, J. W., Correa, A., Cotlarciuc, I., Cruchaga, C., Danesh, J., De Bakker, P. I. W., Destefano, A. L., Hoed, M. D., Duan, Q., Engelter, S. T., Falcone, G. J., Gottesman, R. F., Grewal, R. P., Gudnason, V., Gustafsson, S., Haessler, J., Harris, T. B., Hassan, A., Havulinna, A. S., Heckbert, S. R., Holliday, E. G., Howard, G., Hsu, F. C., Hyacinth, H. I., Ikram, M. A., Ingelsson, E., Irvin, M. R., Jian, X., Jiménez-Conde, J., Johnson, J. A., Jukema, J. W., Kanai, M., Keene, K. L., Kissela, B. M., Kleindorfer, D. O., Kooperberg, C., Kubo, M., Lange, L. A., Langefeld, C. D., Langenberg, C., Launer, L. J., Lee, J. M., Lemmens, R., Leys, D., Lewis, C. M., Lin, W. Y., Lindgren, A. G., Lorentzen, E., Magnusson, P. K., Maguire, J., Manichaikul, A., McArdle, P. F., Meschia, J. F., Mitchell, B. D., Mosley, T. H., Nalls, M. A., Ninomiya, T., O'Donnell, M. J., Psaty, B. M., Pulit, S. L., Rannikmäe, K., Reiner, A. P., Rexrode, K. M., Rice, K., Rich, S. S., Ridker, P. M., Rost, N. S., Rothwell, P. M., Rotter, J. I., Rundek, T., Sacco, R. L., Sakaue, S., Sale, M. M., Salomaa, V., Sapkota, B. R., Schmidt, R., Schmidt, C. O., Schminke, U., Sharma, P., Slowik, A., Sudlow, C. L. M., Tanislav, C., Tatlisumak, T., Taylor, K. D., Thijs, V. N. S., Thorleifsson, G., Thorsteinsdottir, U., Tiedt, S., Trompet, S., Tzourio, C., Van Duijn, C. M., Walters, M., Wareham, N. J., Wassertheil-Smoller, S., Wilson, J. G., Wiggins, K. L., Yang, Q., Yusuf, S., Amin, N., Aparicio, H. S., Arnett, D. K., Attia, J., Beiser, A. S., Berr, C., Buring, J. E., Bustamante, M., Caso, V., Cheng, Y. C., Choi, S. H., Chowhan, A., Cullell, N., Dartigues, J. F., Delavaran, H., Delgado, P., Dörr, M., Engström, G., Ford, I., Gurpreet, W. S., Hamsten, A., Heitsch, L., Hozawa, A., Ibanez, L., Ilinca, A., Ingelsson, M., Iwasaki, M., Jackson, R. D., Jood, K., Jousilahti, P., Kaffashian, S., Kalra, L., Kamouchi, M., Kitazono, T., Kjartansson, O., Kloss, M., Koudstaal, P. J., Krupinski, J., Labovitz, D. L., Laurie, C. C., Levi, C. R., Li, L., Lind, L., Lindgren, C. M., Lioutas, V., Liu, Y. M., Lopez, O. L., Makoto, H., Martinez-Majander, N., Matsuda, K., Minegishi, N., Montaner, J., Morris, A. P., Muiño, E., Müller-Nurasyid, M., Norrving, B., Ogishima, S., Parati, E. A., Peddareddygari, L. R., Pedersen, N. L., Pera, J., Perola, M., Pezzini, A., Pileggi, S., Rabionet, R., Riba-Llena, I., Ribasés, M., Romero, J. R., Roquer, J., Rudd, A. G., Sarin, A. P., Sarju, R., Sarnowski, C., Sasaki, M., Satizabal, C. L., Satoh, M., Sattar, N., Sawada, N., Sibolt, G., Sigurdsson, Á., Smith, A., Sobue, K., Soriano-Tárraga, C., Stanne, T., Stine, O. C., Stott, D. J., Strauch, K., Takai, T., Tanaka, H., Tanno, K., Teumer, A., Tomppo, L., Torres-Aguila, N. P., Touze, E., Tsugane, S., Uitterlinden, A. G., Valdimarsson, E. M., Van Der Lee, S. J., Völzke, H., Wakai, K., Weir, D., Williams, S. R., Wolfe, C. D. A., Wong, Q., Xu, H., Yamaji, T., Sanghera, D. K., Melander, O., Strbian, D., Fernandez-Cadenas, I., Longstreth, W. T., Rolfs, A., Hata, J., Woo, D., Rosand, J., Pare, G., Hopewell, J. C., Saleheen, D., Stefansson, K., Worrall, B. B., Kittner, S. J., Seshadri, S., Fornage, M., Howson, J. M. M., Kamatani, Y., Debette, S. & Dichgans, M., Feb 26 2019, In: Neurology. 92, 9, p. E944-E950

Research output: Contribution to journal › Article › peer-review

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47 Scopus citations

2018

Apolipoprotein E genotypes among diverse middle-aged and older Latinos: Study of Latinos-Investigation of Neurocognitive Aging results (HCHS/SOL)

González, H. M., Tarraf, W., Jian, X., Vásquez, P. M., Kaplan, R., Thyagarajan, B., Daviglus, M., Lamar, M., Gallo, L. C., Zeng, D. & Fornage, M., Dec 1 2018, In: Scientific reports. 8, 1, 17578.

Research output: Contribution to journal › Article › peer-review

Open Access

28 Scopus citations

Exome chip analysis identifies low-frequency and rare variants in MRPL38 for white matter hyperintensities on brain magnetic resonance imaging

neuroCHARGE Working Group, 2018, In: Stroke. 49, 8, p. 1812-1819 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

17 Scopus citations

Functional annotation of genomic variants in studies of late-onset Alzheimer's disease

Butkiewicz, M., Blue, E. E., Leung, Y. Y., Jian, X., Marcora, E., Renton, A. E., Kuzma, A., Wang, L. S., Koboldt, D. C., Haines, J. L. & Bush, W. S., Aug 15 2018, In: Bioinformatics. 34, 16, p. 2724-2731 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease

ARUK Consortium, GERAD/PERADES, CHARGE, ADGC, EADI, International Genomics of Alzheimer's Project (IGAP), ARUK Consortium & GERAD/PERADES, CHARGE, ADGC, EADI, Jan 1 2018, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 10, p. 595-598 4 p.

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Open Access

2 Scopus citations

Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume

Vojinovic, D., Adams, H. H., Jian, X., Yang, Q., Smith, A. V., Bis, J. C., Teumer, A., Scholz, M., Armstrong, N. J., Hofer, E., Saba, Y., Luciano, M., Bernard, M., Trompet, S., Yang, J., Gillespie, N. A., van der Lee, S. J., Neumann, A., Ahmad, S. & Andreassen, O. A. & 71 others, Ames, D., Amin, N., Arfanakis, K., Bastin, M. E., Becker, D. M., Beiser, A. S., Beyer, F., Brodaty, H., Bryan, R. N., Bülow, R., Dale, A. M., De Jager, P. L., Deary, I. J., DeCarli, C., Fleischman, D. A., Gottesman, R. F., van der Grond, J., Gudnason, V., Harris, T. B., Homuth, G., Knopman, D. S., Kwok, J. B., Lewis, C. E., Li, S., Loeffler, M., Lopez, O. L., Maillard, P., El Marroun, H., Mather, K. A., Mosley, T. H., Muetzel, R. L., Nauck, M., Nyquist, P. A., Panizzon, M. S., Pausova, Z., Psaty, B. M., Rice, K., Rotter, J. I., Royle, N., Satizabal, C. L., Schmidt, R., Schofield, P. R., Schreiner, P. J., Sidney, S., Stott, D. J., Thalamuthu, A., Uitterlinden, A. G., Valdés Hernández, M. C., Vernooij, M. W., Wen, W., White, T., Witte, A. V., Wittfeld, K., Wright, M. J., Yanek, L. R., Tiemeier, H., Kremen, W. S., Bennett, D. A., Jukema, J. W., Paus, T., Wardlaw, J. M., Schmidt, H., Sachdev, P. S., Villringer, A., Grabe, H. J., Longstreth, W. T., van Duijn, C. M., Launer, L. J., Seshadri, S., Ikram, M. A. & Fornage, M., Dec 1 2018, In: Nature communications. 9, 1, 3945.

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Open Access

30 Scopus citations

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

MEGASTROKE Consortium, Dec 1 2018, In: Nature communications. 9, 1, 5141.

Research output: Contribution to journal › Article › peer-review

Open Access

105 Scopus citations

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

Neurology Working Group of the CHARGE Consortium, NINDS Stroke Genetics Network (SiGN), UK Young Lacunar DNA Study, MEGAST ROKE Consortium, AFGen Consortium, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, International Genomics of Blood Pressure (iGEN-BP) Consortium, INVENT Consortium, STA RNET BioBank Japan Cooperative Hospital Group, COMPASS Consortium, EPIC-CVD Consortium, EPIC-InterAct Consortium, International Stroke Genetics Consortium (ISGC) & METAST ROKE Consortium, Apr 1 2018, In: Nature Genetics. 50, 4, p. 524-537 14 p.

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Open Access

1121 Scopus citations

Whole genome sequencing of Caribbean Hispanic families with late-onset Alzheimer's disease

The Alzheimer's Disease Sequencing Project, Apr 1 2018, In: Annals of Clinical and Translational Neurology. 5, 4, p. 406-417 12 p.

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Open Access

36 Scopus citations

2017

In silico prediction of deleteriousness for nonsynonymous and splice-altering single nucleotide variants in the human genome

Jian, X. & Liu, X., 2017, In: Methods in Molecular Biology. 1498, p. 191-197 7 p.

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Sims, R., Van Der Lee, S. J., Naj, A. C., Bellenguez, C., Badarinarayan, N., Jakobsdottir, J., Kunkle, B. W., Boland, A., Raybould, R., Bis, J. C., Martin, E. R., Grenier-Boley, B., Heilmann-Heimbach, S., Chouraki, V., Kuzma, A. B., Sleegers, K., Vronskaya, M., Ruiz, A., Graham, R. R. & Olaso, R. & 426 others, Hoffmann, P., Grove, M. L., Vardarajan, B. N., Hiltunen, M., Nöthen, M. M., White, C. C., Hamilton-Nelson, K. L., Epelbaum, J., Maier, W., Choi, S. H., Beecham, G. W., Dulary, C., Herms, S., Smith, A. V., Funk, C. C., Derbois, C., Forstner, A. J., Ahmad, S., Li, H., Bacq, D., Harold, D., Satizabal, C. L., Valladares, O., Squassina, A., Thomas, R., Brody, J. A., Qu, L., Sánchez-Juan, P., Morgan, T., Wolters, F. J., Zhao, Y., Garcia, F. S., Denning, N., Fornage, M., Malamon, J., Naranjo, M. C. D., Majounie, E., Mosley, T. H., Dombroski, B., Wallon, D., Lupton, M. K., Dupuis, J., Whitehead, P., Fratiglioni, L., Medway, C., Jian, X., Mukherjee, S., Keller, L., Brown, K., Lin, H., Cantwell, L. B., Panza, F., McGuinness, B., Moreno-Grau, S., Burgess, J. D., Solfrizzi, V., Proitsi, P., Adams, H. H., Allen, M., Seripa, D., Pastor, P., Cupples, L. A., Price, N. D., Hannequin, D., Frank-García, A., Levy, D., Chakrabarty, P., Caffarra, P., Giegling, I., Beiser, A. S., Giedraitis, V., Hampel, H., Garcia, M. E., Wang, X., Lannfelt, L., Mecocci, P., Eiriksdottir, G., Crane, P. K., Pasquier, F., Boccardi, V., Henández, I., Barber, R. C., Scherer, M., Tarraga, L., Adams, P. M., Leber, M., Chen, Y., Albert, M. S., Riedel-Heller, S., Emilsson, V., Beekly, D., Braae, A., Schmidt, R., Blacker, D., Masullo, C., Schmidt, H., Doody, R. S., Spalletta, G., Longstreth, W. T., Fairchild, T. J., Bossù, P., Lopez, O. L., Frosch, M. P., Sacchinelli, E., Ghetti, B., Yang, Q., Huebinger, R. M., Jessen, F., Li, S., Kamboh, M. I., Morris, J. C., Sotolongo-Grau, O., Katz, M. 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M., Haapasalo, A., Dermecourt, V., Fievet, N., Hanon, O., Dufouil, C., Brice, A., Ritchie, K., Dubois, B., Himali, J. J., Keene, C. D., Tschanz, J., Fitzpatrick, A. L., Kukull, W. A., Norton, M., Aspelund, T., Larson, E. B., Munger, R., Rotter, J. I., Lipton, R. B., Bullido, M. J., Hofman, A., Montine, T. J., Coto, E., Boerwinkle, E., Petersen, R. C., Alvarez, V., Rivadeneira, F., Reiman, E. M., Gallo, M., O'Donnell, C. J., Reisch, J. S., Bruni, A. C., Royall, D. R., Dichgans, M., Sano, M., Galimberti, D., St George-Hyslop, P., Scarpini, E., Tsuang, D. W., Mancuso, M., Bonuccelli, U., Winslow, A. R., Daniele, A., Wu, C. K., Peters, O., Nacmias, B., Riemenschneider, M., Heun, R., Brayne, C., Rubinsztein, D. C., Bras, J., Guerreiro, R., Al-Chalabi, A., Shaw, C. E., Collinge, J., Mann, D., Clarimón, J., Sussams, R., Lovestone, S., O'Donovan, M. C., Owen, M. J., Behrens, T. W., Mead, S., Uitterlinden, A. G., Holmes, C., Cruchaga, C., Ingelsson, M., Bennett, D. A., Powell, J., Golde, T. E., Graff, C., De Jager, P. L., Morgan, K., Ertekin-Taner, N., Combarros, O., Psaty, B. M., Passmore, P., Younkin, S. G., Berr, C., Gudnason, V., Rujescu, D., Dickson, D. W., Dartigues, J. F., Destefano, A. L., Ortega-Cubero, S., Hakonarson, H., Campion, D., Boada, M., Kauwe, J. K., Farrer, L. A., Van Broeckhoven, C., Ikram, M. A., Jones, L., Haines, J. L., Tzourio, C., Launer, L. J., Escott-Price, V., Mayeux, R., Deleuze, J. F., Amin, N., Goate, A. M., Pericak-Vance, M. A., Holmans, P. A., Van Duijn, C. M., Ramirez, A., Wang, L. S., Lambert, J. C., Seshadri, S., Williams, J. & Schellenberg, G. D., Sep 1 2017, In: Nature Genetics. 49, 9, p. 1373-1384 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

681 Scopus citations

2016

Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies

The Cervical Artery Dissection and Ischemic Stroke Patients (CADISP) study, The METASTROKE consortium & The Neurology Working Group of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, the Stroke Genetics Network (SiGN), and the International Stroke Genetics Consortium (ISGC), Jun 1 2016, In: The Lancet Neurology. 15, 7, p. 695-707 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

131 Scopus citations

2015

Comparison and integration of deleteriousness prediction methods for nonsynonymous SNVs in whole exome sequencing studies

Dong, C., Wei, P., Jian, X., Gibbs, R., Boerwinkle, E., Wang, K. & Liu, X., Apr 15 2015, In: Human molecular genetics. 24, 8, p. 2125-2137 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

809 Scopus citations

2014

In silico prediction of splice-altering single nucleotide variants in the human genome

Jian, X., Boerwinkle, E. & Liu, X., Dec 16 2014, In: Nucleic acids research. 42, 22, p. 13534-13544 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

384 Scopus citations

2013

dbNSFP v2.0: A database of human non-synonymous SNVs and their functional predictions and annotations

Liu, X., Jian, X. & Boerwinkle, E., Sep 2013, In: Human mutation. 34, 9, p. E2393-E2402

Research output: Contribution to journal › Article › peer-review

Open Access

493 Scopus citations

2012

Polymorphisms in ABLIM1 are associated with personality traits and alcohol dependence.

Wang, K. S., Liu, X., Aragam, N., Mullersman, J. E., Jian, X., Pan, Y. & Liu, Y., Feb 2012, In: Journal of molecular neuroscience : MN. 46, 2, p. 265-271 7 p.

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

2011

Association of ADAM10 and CAMK2A polymorphisms with conduct disorder: Evidence from family-based studies

Jian, X. Q., Wang, K. S., Wu, T. J., Hillhouse, J. J. & Mullersman, J. E., Aug 2011, In: Journal of Abnormal Child Psychology. 39, 6, p. 773-782 10 p.

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

dbNSFP: A lightweight database of human nonsynonymous SNPs and their functional predictions

Liu, X., Jian, X. & Boerwinkle, E., Aug 2011, In: Human mutation. 32, 8, p. 894-899 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

609 Scopus citations

Family-based association analysis of alcohol dependence in the COGA sample and replication in the Australian twin-family study

Wang, K. S., Liu, X., Aragam, N., Jian, X., Mullersman, J. E., Liu, Y. & Pan, Y., Sep 2011, In: Journal of Neural Transmission. 118, 9, p. 1293-1299 7 p.

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Xueqiu Jian

Research output

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