Research output per year
Research output per year
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Dive into the research topics where Xianlin Han is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Alzheimer's disease risk ABCA7 p.A696S variant disturbs the microglial response to amyloid pathology in mice
Ma, X., Prokopenko, D., Wang, N., Aikawa, T., Choi, Y., Zhang, C., Lei, D., Ren, Y., Kawatani, K., Starling, S. C., Perkerson, R. B., Roy, B., Quintero, A. C., Parsons, T. M., Pan, Y., Li, Z., Wang, M., Bao, H., Han, X. & Bu, G. & 2 others, , Mar 2025, In: Neurobiology of Disease. 206, 106813.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Consuming a modified Mediterranean ketogenic diet reverses the peripheral lipid signature of Alzheimer’s disease in humans
Neth, B. J., Huynh, K., Giles, C., Wang, T., Mellett, N. A., Duong, T., Blach, C., Schimmel, L., Register, T. C., Blennow, K., Zetterberg, H., Batra, R., Schweickart, A., Dilmore, A. H., Martino, C., Arnold, M., Krumsiek, J., Han, X., Dorrestein, P. C. & Knight, R. & 3 others, , Dec 2025, In: Communications Medicine. 5, 1, 11.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
GRAMD1B is a regulator of lipid homeostasis, autophagic flux and phosphorylated tau
Acosta Ingram, D., Turkes, E., Kim, T. Y., Vo, S., Sweeney, N., Bonte, M. A., Rutherford, R., Julian, D. L., Pan, M., Marsh, J., Argouarch, A. R., Wu, M., Scharre, D. W., Bell, E. H., Honig, L. S., Vonsattel, J. P., Serrano, G. E., Beach, T. G., Karch, C. M. & Kao, A. W. & 3 others, , Dec 2025, In: Nature communications. 16, 1, 3312.Research output: Contribution to journal › Article › peer-review
Open Access -
Ketogenesis supports hepatic polyunsaturated fatty acid homeostasis via fatty acid elongation
Queathem, E. D., Moazzami, Z., Stagg, D. B., Nelson, A. B., Fulghum, K., Hayir, A., Seay, A., Gillingham, J. R., d'Avignon, D. A., Han, X., Ruan, H. B., Crawford, P. A. & Puchalska, P., Jan 31 2025, In: Science Advances. 11, 5, eads0535.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Lipidome disruption in Alzheimer’s disease brain: detection, pathological mechanisms, and therapeutic implications
He, S., Xu, Z. & Han, X., Dec 2025, In: Molecular Neurodegeneration. 20, 1, 11.Research output: Contribution to journal › Review article › peer-review
Open Access2 Scopus citations
Datasets
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Metadata record for: Bile acids targeted metabolomics and medication classification data in the ADNI1 and ADNIGO/2 cohorts
St. John-Williams, L. (Contributor), Mahmoudiandehkordi, S. (Contributor), Arnold, M. (Creator), Massaro, T. (Creator), Blach, C. (Creator), Kastenmüller, G. (Creator), Louie, G. (Creator), Kueider-Paisley, A. (Creator), Han, X. (Contributor), Baillie, R. (Creator), Motsinger-Reif, A. A. (Creator), Rotroff, D. (Creator), Nho, K. (Contributor), Saykin, A. J. (Creator), Risacher, S. L. (Creator), Koal, T. (Creator), Moseley, M. A. (Contributor), Tenenbaum, J. D. (Creator), Thompson, J. W. (Contributor), Kaddurah-Daouk, R. (Creator) & Rotroff, D. (Creator), Figshare, 2020
DOI: 10.6084/m9.figshare.9724652.v3, https://springernature.figshare.com/articles/Metadata_record_for_Bile_acids_targeted_metabolomics_and_medication_classification_data_in_the_ADNI1_and_ADNIGO_2_cohorts/9724652/3
Dataset
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APOE2 orchestrated differences in transcriptomic and lipidomic profiles of postmortem AD brain
Lefterov, I. (Creator), Wolfe, C. M. (Creator), Fitz, N. F. (Creator), Nam, K. N. (Creator), Letronne, F. (Creator), Biedrzycki, R. J. (Creator), Kofler, J. (Creator), Han, X. (Creator), Wang, J. (Creator), Schug, J. (Creator) & Koldamova, R. (Creator), Figshare, 2019
DOI: 10.6084/m9.figshare.c.4801596.v1, https://springernature.figshare.com/collections/APOE2_orchestrated_differences_in_transcriptomic_and_lipidomic_profiles_of_postmortem_AD_brain/4801596/1
Dataset
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Metadata record for: Bile acids targeted metabolomics and medication classification data in the ADNI1 and ADNIGO/2 cohorts
St. John-Williams, L. (Contributor), Mahmoudiandehkordi, S. (Contributor), Arnold, M. (Creator), Massaro, T. (Creator), Blach, C. (Creator), Kastenmüller, G. (Creator), Louie, G. (Creator), Kueider-Paisley, A. (Creator), Han, X. (Contributor), Baillie, R. (Creator), Motsinger-Reif, A. A. (Creator), Rotroff, D. (Creator), Nho, K. (Contributor), Saykin, A. J. (Creator), Risacher, S. L. (Creator), Koal, T. (Creator), Moseley, M. A. (Contributor), Tenenbaum, J. D. (Creator), Thompson, J. W. (Contributor) & Kaddurah-Daouk, R. (Creator), Figshare, 2019
DOI: 10.6084/m9.figshare.9724652.v1, https://springernature.figshare.com/articles/Metadata_record_for_Bile_acids_targeted_metabolomics_and_medication_classification_data_in_the_ADNI1_and_ADNIGO_2_cohorts/9724652/1
Dataset
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PNPLA3 is a triglyceride lipase that mobilizes polyunsaturated fatty acids to facilitate hepatic secretion of large-sized very low-density lipoprotein
Johnson, S. M. (Contributor), Bao, H. (Contributor), McMahon, C. E. (Contributor), Chen, Y. (Contributor), Burr, S. D. (Contributor), Anderson, A. M. (Contributor), Madeyski-Bengtson, K. (Contributor), Lindén, D. (Contributor), Han, X. (Contributor) & Liu, J. (Creator), Figshare, 2024
DOI: 10.6084/m9.figshare.25408177.v1, https://springernature.figshare.com/articles/dataset/PNPLA3_is_a_triglyceride_lipase_that_mobilizes_polyunsaturated_fatty_acids_to_facilitate_hepatic_secretion_of_large-sized_very_low-density_lipoprotein/25408177/1
Dataset
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MOESM2 of APOE2 orchestrated differences in transcriptomic and lipidomic profiles of postmortem AD brain
Lefterov, I. (Creator), Wolfe, C. M. (Creator), Fitz, N. F. (Creator), Nam, K. N. (Creator), Letronne, F. (Creator), Biedrzycki, R. J. (Creator), Kofler, J. (Creator), Han, X. (Creator), Wang, J. (Creator), Schug, J. (Creator) & Koldamova, R. (Creator), Figshare, 2019
DOI: 10.6084/m9.figshare.11480532, https://springernature.figshare.com/articles/figure/MOESM2_of_APOE2_orchestrated_differences_in_transcriptomic_and_lipidomic_profiles_of_postmortem_AD_brain/11480532
Dataset