Wouter Koek

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9 Similar Profiles

Receptor, Serotonin, 5-HT1A Medicine & Life Sciences

Serotonin Medicine & Life Sciences

8-Hydroxy-2-(di-n-propylamino)tetralin Medicine & Life Sciences

Catalepsy Medicine & Life Sciences

Columbidae Medicine & Life Sciences

Hydroxybutyrates Medicine & Life Sciences

Phencyclidine Medicine & Life Sciences

Baclofen Medicine & Life Sciences

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Projects 2003 2016

4 Finished

Organic Cation Transporters as Targets for Novel Antidepressant Drugs

Daws, L. C. & Koek, W.

National Institutes of Health

3/1/12 → 11/30/16

Project: Research project

Antidepressive Agents

Cations

Serotonin

Membrane Transport Proteins

Cell Membrane

Vulnerability to Opioids: A Mouse Model

Koek, W.

National Institutes of Health

9/15/08 → 5/31/13

Project: Research project

Opioid Analgesics

Morphine

Prescriptions

Rodentia

Public Health

Discriminative Stimulus Effects of Alcohol in Mice

Koek, W.

National Institutes of Health

9/30/06 → 8/31/09

Project: Research project

Alcohols

Substance-Related Disorders

Pharmaceutical Preparations

Alcoholism

Rodentia

Neuropharmacology of GHB discrimination

Koek, W.

National Institutes of Health

4/1/03 → 8/31/12

Project: Research project

Neuropharmacology

Sodium Oxybate

Baclofen

Pharmaceutical Preparations

Pharmacology

Research Output 1981 2019

5147 Citations
38 h-Index
182 Article
1 Chapter

1 Citation (Scopus)

Comparative analysis of novel decynium-22 analogs to inhibit transport by the low-affinity, high-capacity monoamine transporters, organic cation transporters 2 and 3, and plasma membrane monoamine transporter

Fraser-Spears, R., Krause-Heuer, A. M., Basiouny, M., Mayer, F. P., Manishimwe, R., Wyatt, N. A., Dobrowolski, J. C., Roberts, M. P., Greguric, I., Kumar, N., Koek, W., Sitte, H. H., Callaghan, P. D., Fraser, B. H. & Daws, L. C., Jan 5 2019, In : European Journal of Pharmacology. 842, p. 351-364 14 p.

Research output: Contribution to journal › Article

Membrane Transport Proteins

Cations

Cell Membrane

Antidepressive Agents

nisoxetine

6 Citations (Scopus)

An unsuspected role for organic cation transporter 3 in the actions of amphetamine

Mayer, F. P., Schmid, D., Owens, W. A., Gould, G. G., Apuschkin, M., Kudlacek, O., Salzer, I., Boehm, S., Chiba, P., Williams, P. H., Wu, H. H., Gether, U., Koek, W., Daws, L. C. & Sitte, H. H., Apr 6 2018, (Accepted/In press) In : Neuropsychopharmacology. p. 1-10 10 p.

Research output: Contribution to journal › Article

Amphetamine

Cations

Cocaine

Amphetamine-Related Disorders

Amphetamines

8 Citations (Scopus)

A randomized control trial to establish the feasibility and safety of rapamycin treatment in an older human cohort: Immunological, physical performance, and cognitive effects

Kraig, E. B., Linehan, L. A., Liang, H., Romo, T. Q., Liu, Q., Wu, Y., Benavides, A. D., Curiel, T. J., Javors, M. A., Musi, N., Chiodo, L., Koek, W., Gelfond, J. A. & Kellogg Jr, D. L., Jan 1 2018, (Accepted/In press) In : Experimental Gerontology.

Research output: Contribution to journal › Article

Sirolimus

Safety

Therapeutics

Erythrocyte Indices

Clinical laboratories

1 Citation (Scopus)

Biphasic effects of selective serotonin reuptake inhibitors on anxiety: Rapid reversal of escitalopram's anxiogenic effects in the novelty-induced hypophagia test in mice?

Koek, W., Mitchell, N. C. & Daws, L. C., Jan 1 2018, In : Behavioural Pharmacology. 29, 4, p. 365-369 5 p.

Research output: Contribution to journal › Article

Citalopram

Serotonin Uptake Inhibitors

Anxiety

Anti-Anxiety Agents

Survival Analysis

2 Citations (Scopus)

Constitutive plasma membrane monoamine transporter (PMAT, Slc29a4) deficiency subtly affects anxiety-like and coping behaviours

Gilman, T. L., George, C. M., Vitela, M., Herrera-Rosales, M., Basiouny, M. S., Koek, W. & Daws, L. C., Jul 1 2018, In : European Journal of Neuroscience. 48, 1, p. 1706-1716 11 p.

Research output: Contribution to journal › Article

Membrane Transport Proteins

Psychological Adaptation

Anxiety

Cell Membrane

Knockout Mice