William P Clarke

  • 3593 Citations
  • 33 h-Index
1981 …2020
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  • 14 Similar Profiles
Receptor, Serotonin, 5-HT2C Medicine & Life Sciences
Serotonin Medicine & Life Sciences
Sensory Receptor Cells Medicine & Life Sciences
Bradykinin Medicine & Life Sciences
Ligands Medicine & Life Sciences
Arachidonic Acid Medicine & Life Sciences
Serotonin Receptors Medicine & Life Sciences
Receptor, Serotonin, 5-HT2A Medicine & Life Sciences

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Projects 1992 2020

Sensory Receptor Cells
salvinorin A
Ligands
Drug Discovery
Pharmaceutical Preparations

Aging, peripheral pain and analgesia

Clarke, W. P.

National Institutes of Health

2/1/151/31/17

Project: Research projectExploratory/Developmental Grants

Nociceptors
Analgesia
Pain
Opioid Receptors
Analgesics

Regulation of DOR-KOR heteromer formation in pain-sensing neurons

Clarke, W. P.

National Institutes of Health

9/1/148/31/16

Project: Research projectExploratory/Developmental Grants

G-Protein-Coupled Receptors
Neurons
Pain
Nociceptors
Protein Subunits
kappa Opioid Receptor
Sensory Receptor Cells
Analgesia
Pain
Opioid Receptors
Trigeminal Ganglion
Opioid Receptors
Mental Competency
Bradykinin
Naloxone

Research Output 1981 2018

  • 3593 Citations
  • 33 h-Index
  • 71 Article
  • 1 Review article

Allosterism within d opioid-k opioid receptor heteromers in peripheral sensory neurons: Regulation of k opioid agonist efficacy

Jacobs, B. A., Pando, M. M., Jennings, E., Chavera, T. A., Clarke, W. P. & Berg, K. A., Apr 1 2018, In : Molecular Pharmacology. 93, 4, p. 376-386 11 p.

Research output: Contribution to journalArticle

Opioid Receptors
Sensory Receptor Cells
Nociceptors
naltrindole
Opioid Analgesics

Making sense of pharmacology: Inverse agonism and functional selectivity

Berg, K. A. & Clarke, W. P., Oct 1 2018, In : International Journal of Neuropsychopharmacology. 21, 10, p. 962-977 16 p.

Research output: Contribution to journalReview article

Pharmacology
Pharmaceutical Preparations
Ligands
Research
Medicine
2 Citations

Pharmacological augmentation of nicotinamide phosphoribosyltransferase (NAMPT) protects against paclitaxel-induced peripheral neuropathy

LoCoco, P. M., Risinger, A. L., Smith, H. R., Chavera, T. S., Berg, K. A. & Clarke, W. P., Nov 10 2017, In : eLife. 6, e29626.

Research output: Contribution to journalArticle

Nicotinamide Phosphoribosyltransferase
Peripheral Nervous System Diseases
Paclitaxel
Chemotherapy
Pharmacology
3 Citations

Constitutive desensitization of opioid receptors in peripheral sensory neurons

Sullivan, L. C., Chavera, T. S., Jamshidi, R. J., Berg, K. A. & Clarke, W. P., Dec 1 2016, In : Journal of Pharmacology and Experimental Therapeutics. 359, 3, p. 411-419 9 p.

Research output: Contribution to journalArticle

Opioid Receptors
Sensory Receptor Cells
Naloxone
Enkephalins
Bradykinin
2 Citations
kappa Opioid Receptor
JNK Mitogen-Activated Protein Kinases
Sensory Receptor Cells
Ligands
Proteins

Press/Media

All in on Mass Spectrometry

William P Clarke

9/14/18

1 item of media coverage

Press/Media: Press / Media

Mass Spectrometry and Separation Sciences for Laboratory Medicine

William P Clarke

8/17/18

1 item of media coverage

Press/Media: Press / Media

Executive items

William P Clarke

7/4/16

1 item of media coverage

Press/Media: Press / Media

Dennis J. Armento, schoolteacher

William P Clarke

6/1/16

2 items of media coverage

Press/Media: Press / Media