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William P Clarke

  • 3917 Citations
  • 34 h-Index
1981 …2019

Research output per year

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Projects

KOR agonist functional selectivity in peripheral sensory neurons

Clarke, W. P. & Berg, K. A.

National Institutes of Health

9/15/15 → 7/31/20

Project: Research project

    • Sumatriptan and MOH: Differential 5-HT1R signaling in trigeminal nociceptors

    Clarke, W. P. & Berg, K. A.

    Project: Research project

    Pharmacological and behavioral effects of MCAM: a long-acting, ? opioid receptor antagonist for treatment of opioid overdose and opioid abuse disorder

    Clarke, W. P.

    Project: Research project

    Aging, peripheral pain and analgesia

    Clarke, W. P.

    National Institutes of Health

    2/1/15 → 1/31/17

    Project: Research project

    • Regulation of DOR-KOR heteromer formation in pain-sensing neurons

    Clarke, W. P.

    National Institutes of Health

    9/1/14 → 8/31/16

    Project: Research project

    • Research Output

    • 3917 Citations
    • 34 h-Index
    • 62 Article
    • 8 Review article
    • 2 Chapter
    • 1 Letter

    Signaling characteristics and functional regulation of delta opioid-kappa opioid receptor (DOP-KOP) heteromers in peripheral sensory neurons

    Jacobs, B. A., Pando, M. M., Jennings, E. M., Jamshidi, R. J., Zamora, J. C., Chavera, T. S., Clarke, W. P. & Berg, K. A., Jun 2019, In : Neuropharmacology. 151, p. 208-218 11 p.

    Research output: Contribution to journal › Article

    • 2 Scopus citations

    Allosterism within d opioid-k opioid receptor heteromers in peripheral sensory neurons: Regulation of k opioid agonist efficacy

    Jacobs, B. A., Pando, M. M., Jennings, E., Chavera, T. A., Clarke, W. P. & Berg, K. A., Apr 1 2018, In : Molecular Pharmacology. 93, 4, p. 376-386 11 p.

    Research output: Contribution to journal › Article

    • 7 Scopus citations

    Making sense of pharmacology: Inverse agonism and functional selectivity

    Berg, K. A. & Clarke, W. P., Oct 1 2018, In : International Journal of Neuropsychopharmacology. 21, 10, p. 962-977 16 p.

    Research output: Contribution to journal › Review article

    • 17 Scopus citations

    Pharmacological augmentation of nicotinamide phosphoribosyltransferase (NAMPT) protects against paclitaxel-induced peripheral neuropathy

    LoCoco, P. M., Risinger, A. L., Smith, H. R., Chavera, T. S., Berg, K. A. & Clarke, W. P., Nov 10 2017, In : eLife. 6, e29626.

    Research output: Contribution to journal › Article

    • 10 Scopus citations

    Constitutive desensitization of opioid receptors in peripheral sensory neurons

    Sullivan, L. C., Chavera, T. S., Jamshidi, R. J., Berg, K. A. & Clarke, W. P., Dec 2016, In : Journal of Pharmacology and Experimental Therapeutics. 359, 3, p. 411-419 9 p.

    Research output: Contribution to journal › Article

    • 4 Scopus citations

    Press / Media

    Long-lasting treatment drug could slow the opioid crisis

    Martin A Javors, William P Clarke, Charles P France, Kelly A Berg, David R Maguire & James H Woods

    3/8/20

    1 item of Media coverage

    Press/Media: Press / Media

    Sybil Williams-Clarke, 96, widow of historian John Henrik Clarke

    William P Clarke

    10/21/19

    2 items of Media coverage

    Press/Media: Press / Media

    Starting HIV Treatment in ERs May Be Key to Ending HIV Spread Worldwide

    William P Clarke

    9/16/19 → 9/17/19

    2 items of Media coverage

    Press/Media: Press / Media

    Johns Hopkins: Starting HIV Treatment in ERs May Be Key to Ending HIV Spread Worldwide

    William P Clarke

    9/16/19

    1 item of Media coverage

    Press/Media: Press / Media

    Starting HIV Treatment In ERs May Be Key To Ending HIV Spread Worldwide

    William P Clarke

    9/16/19

    1 item of Media coverage

    Press/Media: Press / Media