Weixing Zhao

  • 1034 Citations
  • 18 h-Index
20052020

Research output per year

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Research Output

  • 1034 Citations
  • 18 h-Index
  • 30 Article
  • 2 Comment/debate
  • 1 Chapter
  • 1 Review article
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Article
2020

The DNA-binding activity of USP1-associated factor 1 is required for efficient RAD51-mediated homologous DNA pairing and homology-directed DNA repair

Liang, F., Miller, A. S., Tang, C., Maranon, D., Williamson, E. A., Hromas, R. A., Wiese, C., Zhao, W., Sung, P. & Kupfer, G. M., Jun 12 2020, In : The Journal of biological chemistry. 295, 24, p. 8186-8194 9 p.

Research output: Contribution to journalArticle

2019

Defining the influence of Rad51 and Dmc1 lineage-specific amino acids on genetic recombination

Steinfeld, J. B., Beláň, O., Kwon, Y., Terakawa, T., Al-Zain, A., Smith, M. J., Crickard, J. B., Qi, Z., Zhao, W., Rothstein, R., Symington, L. S., Sung, P., Boulton, S. J. & Greene, E. C., Sep 1 2019, In : Genes and Development. 33, 17-18, p. 1191-1207 17 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

MiR223-3p promotes synthetic lethality in BRCA1-deficient cancers

Srinivasan, G., Williamson, E. A., Kong, K., Jaiswal, A. S., Huang, G., Kim, H. S., Schärer, O., Zhao, W., Burma, S., Sung, P. & Hromas, R., Aug 27 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 35, p. 17438-17443 6 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2018

Importance of homo-dimerization of Fanconi-associated nuclease 1 in DNA flap cleavage

Rao, T., Longerich, S., Zhao, W., Aihara, H., Sung, P. & Xiong, Y., Apr 2018, In : DNA Repair. 64, p. 53-58 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

RAD52 is required for RNA-templated recombination repair in post-mitotic neurons

Welty, S., Teng, Y., Liang, Z., Zhao, W., Sanders, L. H., Greenamyre, J. T., Rubio, M. E., Thathiah, A., Kodali, R., Wetzel, R., Levine, A. S. & Lan, L., Jan 26 2018, In : Journal of Biological Chemistry. 293, 4, p. 1353-1362 10 p.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations
2017

BRCA1-BARD1 promotes RAD51-mediated homologous DNA pairing

Zhao, W., Steinfeld, J. B., Liang, F., Chen, X., Maranon, D. G., Jian Ma, C., Kwon, Y., Rao, T., Wang, W., Sheng, C., Song, X., Deng, Y., Jimenez-Sainz, J., Lu, L., Jensen, R. B., Xiong, Y., Kupfer, G. M., Wiese, C., Greene, E. C. & Sung, P., Oct 19 2017, In : Nature. 550, 7676, nature24060.

Research output: Contribution to journalArticle

73 Scopus citations

Cryo-EM structures of human RAD51 recombinase filaments during catalysis of DNA-strand exchange

Xu, J., Zhao, L., Xu, Y., Zhao, W., Sung, P. & Wang, H. W., Jan 5 2017, In : Nature Structural and Molecular Biology. 24, 1, p. 40-46 7 p.

Research output: Contribution to journalArticle

35 Scopus citations
2016

Non-catalytic Roles for XPG with BRCA1 and BRCA2 in Homologous Recombination and Genome Stability

Trego, K. S., Groesser, T., Davalos, A. R., Parplys, A. C., Zhao, W., Nelson, M. R., Hlaing, A., Shih, B., Rydberg, B., Pluth, J. M., Tsai, M. S., Hoeijmakers, J. H. J., Sung, P., Wiese, C., Campisi, J. & Cooper, P. K., Feb 18 2016, In : Molecular Cell. 61, 4, p. 535-546 12 p.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations

Tolerance of DNA mismatches in dmc1 recombinase-mediated DNA strand exchange

Borgogno, M. V., Monti, M. R., Zhao, W., Sung, P., Argarana, C. E. & Pezza, R. J., Mar 4 2016, In : Journal of Biological Chemistry. 291, 10, p. 4928-4938 11 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations
2015

Base triplet stepping by the Rad51/RecA family of recombinases

Lee, J. Y., Terakawa, T., Qi, Z., Steinfeld, J. B., Redding, S., Kwon, Y. H., Gaines, W. A., Zhao, W., Sung, P. & Greene, E. C., Aug 28 2015, In : Science. 349, 6251, p. 977-981 5 p.

Research output: Contribution to journalArticle

Open Access
71 Scopus citations

NUCKS1 is a novel RAD51AP1 paralog important for homologous recombination and genome stability

Parplys, A. C., Zhao, W., Sharma, N., Groesser, T., Liang, F., Maranon, D. G., Leung, S. G., Grundt, K., Dray, E., Idate, R., Østvold, A. C., Schild, D., Sung, P. & Wiese, C., Aug 17 2015, In : Nucleic acids research. 43, 20, p. 9817-9834 18 p.

Research output: Contribution to journalArticle

Open Access
22 Scopus citations

Promotion of BRCA2-Dependent Homologous Recombination by DSS1 via RPA Targeting and DNA Mimicry

Zhao, W., Vaithiyalingam, S., San Filippo, J., Maranon, D. G., Jimenez-Sainz, J., Fontenay, G. V., Kwon, Y., Leung, S. G., Lu, L., Jensen, R. B., Chazin, W. J., Wiese, C. & Sung, P., Jul 16 2015, In : Molecular Cell. 59, 2, p. 176-187 12 p.

Research output: Contribution to journalArticle

Open Access
58 Scopus citations
Open Access
24 Scopus citations
2014

Breast cancer proteins PALB2 and BRCA2 stimulate polymerase η in recombination-associated DNA Synthesis At Blocked Replication Forks

Buisson, R., Niraj, J., Pauty, J., Maity, R., Zhao, W., Coulombe, Y., Sung, P. & Masson, J. Y., Feb 13 2014, In : Cell Reports. 6, 3, p. 553-564 12 p.

Research output: Contribution to journalArticle

Open Access
48 Scopus citations

Mechanistic insights into the role of Hop2-Mnd1 in meiotic homologous DNA pairing

Zhao, W., Saro, D., Hammel, M., Kwon, Y., Xu, Y., Rambo, R. P., Williams, G. J., Chi, P., Lu, L., Pezza, R. J., Camerini-Otero, R. D., Tainer, J. A., Wang, H. W. & Sung, P., 2014, In : Nucleic acids research. 42, 2, p. 906-917 12 p.

Research output: Contribution to journalArticle

Open Access
32 Scopus citations

Solution structure and DNA-binding properties of the winged helix domain of the meiotic recombination HOP2 protein

Moktan, H., Guiraldelli, M. F., Eyster, C. A., Zhao, W., Lee, C. Y., Mather, T., Camerini-Otero, R. D., Sung, P., Zhou, D. H. & Pezza, R. J., Jan 1 2014, In : Journal of Biological Chemistry. 289, 21, p. 14682-14691 10 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations
2012

Mechanistic insights into RAD51-associated protein 1 (RAD51AP1) action in homologous DNA repair

Dunlop, M. H., Dray, E., Zhao, W., San Filippo, J., Tsai, M. S., Leung, S. G., Schild, D., Wiese, C. & Sung, P., Apr 6 2012, In : Journal of Biological Chemistry. 287, 15, p. 12343-12347 5 p.

Research output: Contribution to journalArticle

Open Access
19 Scopus citations
2011

Biochemical studies on human Rad51-mediated homologous recombination.

Kwon, Y., Zhao, W. & Sung, P., Oct 4 2011, In : Methods in molecular biology (Clifton, N.J.). 745, p. 421-435 15 p.

Research output: Contribution to journalArticle

3 Scopus citations

RAD51-associated protein 1 (RAD51AP1) interacts with the meiotic recombinase DMC1 through a conserved motif

Dunlop, M. H., Dray, E., Zhao, W., Tsai, M. S., Wiese, C., Schild, D. & Sung, P., Oct 28 2011, In : Journal of Biological Chemistry. 286, 43, p. 37328-37334 7 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations
2010

Mechanism of the ATP-dependent DNA endresection machinery from Saccharomyces cerevisiae

Niu, H., Chung, W. H., Zhu, Z., Kwon, Y., Zhao, W., Chi, P., Prakash, R., Seong, C., Liu, D., Lu, L., Ira, G. & Sung, P., Sep 2 2010, In : Nature. 467, 7311, p. 108-111 4 p.

Research output: Contribution to journalArticle

241 Scopus citations
2009

Visualizing the Disassembly of S. cerevisiae Rad51 Nucleoprotein Filaments

Robertson, R. B., Moses, D. N., Kwon, Y. H., Chan, P., Zhao, W., Chi, P., Klein, H., Sung, P. & Greene, E. C., May 15 2009, In : Journal of Molecular Biology. 388, 4, p. 703-720 18 p.

Research output: Contribution to journalArticle

15 Scopus citations
2008

Functional role of BLAP75 in BLM-topoisomerase IIIα-dependent holliday junction processing

Raynard, S., Zhao, W., Bussen, W., Lu, L., Ding, Y. Y., Busygina, V., Meetei, A. R. & Sung, P., Jun 6 2008, In : Journal of Biological Chemistry. 283, 23, p. 15701-15708 8 p.

Research output: Contribution to journalArticle

Open Access
50 Scopus citations
2007
Open Access
28 Scopus citations

MreB is important for cell shape but not for chromosome segregation of the filamentous cyanobacterium Anabaena sp. PCC 7120

Hu, B., Yang, G., Zhao, W., Zhang, Y. & Zhao, J., Mar 1 2007, In : Molecular Microbiology. 63, 6, p. 1640-1652 13 p.

Research output: Contribution to journalArticle

79 Scopus citations

PII is important in regulation of nitrogen metabolism but not required for heterocyst formation in the cyanobacterium Anabaena sp. PCC 7120

Zhang, Y., Pu, H., Wang, Q., Cheng, S., Zhao, W., Zhang, Y. & Zhao, J., Nov 16 2007, In : Journal of Biological Chemistry. 282, 46, p. 33641-33648 8 p.

Research output: Contribution to journalArticle

Open Access
22 Scopus citations
41 Scopus citations

Sample pretreatment microfluidic chip for DNA extraction from rat peripheral blood

Chen, X., Cui, D., Liu, C., Li, H. & Zhao, W., Mar 1 2007, In : Frontiers of Chemistry in China. 2, 1, p. 74-78 5 p.

Research output: Contribution to journalArticle

1 Scopus citations
2006
Open Access
40 Scopus citations

Sample pretreatment microfluidic chip for DNA extraction from rat peripheral blood

Chen, X., Cui, D. F., Liu, C. C., Li, H. & Zhao, W. X., Apr 1 2006, In : Gaodeng Xuexiao Huaxue Xuebao/Chemical Journal of Chinese Universities. 27, 4, p. 618-621 4 p.

Research output: Contribution to journalArticle

1 Scopus citations
2005

CcbP, a calcium-binding protein from Anabaena sp. PCC 7120, provides evidence that calcium ions regulate heterocyst differentiation

Zhao, Y., Shi, Y., Zhao, W., Huang, X., Wang, D., Brown, N., Brand, J. & Zhao, J., Apr 19 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 16, p. 5744-5748 5 p.

Research output: Contribution to journalArticle

Open Access
54 Scopus citations