Sudha Seshadri

  • Source: Scopus
  • Calculated based on no. of publications stored in Pure and citations from Scopus
1989 …2021

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  • 2015

    Circulating brain-derived neurotrophic factor concentrations and the risk of cardiovascular disease in the community

    CARDIoGRAM, Mar 11 2015, In: Journal of the American Heart Association. 4, 3, p. e001544

    Research output: Contribution to journalArticlepeer-review

    72 Scopus citations
  • Coagulation factor XII genetic variation, ex vivo thrombin generation, and stroke risk in the elderly: Results from the Cardiovascular Health Study

    Olson, N. C., Butenas, S., Lange, L. A., Lange, E. M., Cushman, M., Jenny, N. S., Walston, J., Souto, J. C., Soria, J. M., Chauhan, G., Debette, S., Longstreth, W. T., Seshadri, S., Reiner, A. P. & Tracy, R. P., Oct 1 2015, In: Journal of Thrombosis and Haemostasis. 13, 10, p. 1867-1877 11 p.

    Research output: Contribution to journalArticlepeer-review

    6 Scopus citations
  • Common genetic variants influence human subcortical brain structures

    Hibar, D. P., Stein, J. L., Renteria, M. E., Arias-Vasquez, A., Desrivières, S., Jahanshad, N., Toro, R., Wittfeld, K., Abramovic, L., Andersson, M., Aribisala, B. S., Armstrong, N. J., Bernard, M., Bohlken, M. M., Boks, M. P., Bralten, J., Brown, A. A., Mallar Chakravarty, M., Chen, Q., Ching, C. R. K. & 267 others, Cuellar-Partida, G., Den Braber, A., Giddaluru, S., Goldman, A. L., Grimm, O., Guadalupe, T., Hass, J., Woldehawariat, G., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Olde Loohuis, L. M., Luciano, M., MacAre, C., Mather, K. A., Mattheisen, M., Milaneschi, Y., Nho, K., Papmeyer, M., Ramasamy, A., Risacher, S. L., Roiz-Santiañez, R., Rose, E. J., Salami, A., Sämann, P. G., Schmaal, L., Schork, A. J., Shin, J., Strike, L. T., Teumer, A., Van Donkelaar, M. M. J., Van Eijk, K. R., Walters, R. K., Westlye, L. T., Whelan, C. D., Winkler, A. M., Zwiers, M. P., Alhusaini, S., Athanasiu, L., Ehrlich, S., Hakobjan, M. M. H., Hartberg, C. B., Haukvik, U. K., Heister, A. J. G. A. M., Hoehn, D., Kasperaviciute, D., Liewald, D. C. M., Lopez, L. M., Makkinje, R. R. R., Matarin, M., Naber, M. A. M., Reese McKay, D., Needham, M., Nugent, A. C., Pütz, B., Royle, N. A., Shen, L., Sprooten, E., Trabzuni, D., Van Der Marel, S. S. L., Van Hulzen, K. J. E., Walton, E., Wolf, C., Almasy, L., Ames, D., Arepalli, S., Assareh, A. A., Bastin, M. E., Brodaty, H., Bulayeva, K. B., Carless, M. A., Cichon, S., Corvin, A., Curran, J. E., Czisch, M., De Zubicaray, G. I., Dillman, A., Duggirala, R., Dyer, T. D., Erk, S., Fedko, I. O., Ferrucci, L., Foroud, T. M., Fox, P. T., Fukunaga, M., Raphael Gibbs, J., Göring, H. H. H., Green, R. C., Guelfi, S., Hansell, N. K., Hartman, C. A., Hegenscheid, K., Heinz, A., Hernandez, D. G., Heslenfeld, D. J., Hoekstra, P. J., Holsboer, F., Homuth, G., Hottenga, J. J., Ikeda, M., Jack, C. R., Jenkinson, M., Johnson, R., Kanai, R., Keil, M., Kent, J. W., Kochunov, P., Kwok, J. B., Lawrie, S. M., Liu, X., Longo, D. L., McMahon, K. L., Meisenzahl, E., Melle, I., Mohnke, S., Montgomery, G. W., Mostert, J. C., Mühleisen, T. W., Nalls, M. A., Nichols, T. E., Nilsson, L. G., Nöthen, M. M., Ohi, K., Olvera, R. L., Perez-Iglesias, R., Bruce Pike, G., Potkin, S. G., Reinvang, I., Reppermund, S., Rietschel, M., Romanczuk-Seiferth, N., Rosen, G. D., Rujescu, D., Schnell, K., Schofield, P. R., Smith, C., Steen, V. M., Sussmann, J. E., Thalamuthu, A., Toga, A. W., Traynor, B. J., Troncoso, J., Turner, J. A., Valdés Hernández, M. C., Van 'T Ent, D., Van Der Brug, M., Van Der Wee, N. J. A., Van Tol, M. J., Veltman, D. J., Wassink, T. H., Westman, E., Zielke, R. H., Zonderman, A. B., Ashbrook, D. G., Hager, R., Lu, L., McMahon, F. J., Morris, D. W., Williams, R. W., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Cahn, W., Calhoun, V. D., Cavalleri, G. L., Crespo-Facorro, B., Dale, A. M., Davies, G. E., Delanty, N., Depondt, C., Djurovic, S., Drevets, W. C., Espeseth, T., Gollub, R. L., Ho, B. C., Hoffmann, W., Hosten, N., Kahn, R. S., Le Hellard, S., Meyer-Lindenberg, A., Müller-Myhsok, B., Nauck, M., Nyberg, L., Pandolfo, M., Penninx, B. W. J. H., Roffman, J. L., Sisodiya, S. M., Smoller, J. W., Van Bokhoven, H., Van Haren, N. E. M., Völzke, H., Walter, H., Weiner, M. W., Wen, W., White, T., Agartz, I., Andreassen, O. A., Blangero, J., Boomsma, D. I., Brouwer, R. M., Cannon, D. M., Cookson, M. R., De Geus, E. J. C., Deary, I. J., Donohoe, G., Fernández, G., Fisher, S. E., Francks, C., Glahn, D. C., Grabe, H. J., Gruber, O., Hardy, J., Hashimoto, R., Hulshoff Pol, H. E., Jönsson, E. G., Kloszewska, I., Lovestone, S., Mattay, V. S., Mecocci, P., McDonald, C., McIntosh, A. M., Ophoff, R. A., Paus, T., Pausova, Z., Ryten, M., Sachdev, P. S., Saykin, A. J., Simmons, A., Singleton, A., Soininen, H., Wardlaw, J. M., Weale, M. E., Weinberger, D. R., Adams, H. H. H., Launer, L. J., Seiler, S., Schmidt, R., Chauhan, G., Satizabal, C. L., Becker, J. T., Yanek, L., Van Der Lee, S. J., Ebling, M., Fischl, B., Longstreth, W. T., Greve, D., Schmidt, H., Nyquist, P., Vinke, L. N., Van Duijn, C. M., Xue, L., Mazoyer, B., Bis, J. C., Gudnason, V., Seshadri, S., Ikram, M. A., Martin, N. G., Wright, M. J., Schumann, G., Franke, B., Thompson, P. M. & Medland, S. E., Apr 9 2015, In: Nature. 520, 7546, p. 224-229 6 p.

    Research output: Contribution to journalArticlepeer-review

    461 Scopus citations
  • Common polygenic variation enhances risk prediction for Alzheimer's disease

    Escott-Price, V., Sims, R., Bannister, C., Harold, D., Vronskaya, M., Majounie, E., Badarinarayan, N., Morgan, K., Passmore, P., Holmes, C., Powell, J., Brayne, C., Gill, M., Mead, S., Goate, A., Cruchaga, C., Lambert, J. C., Van Duijn, C., Maier, W., Ramirez, A. & 7 others, Holmans, P., Jones, L., Hardy, J., Seshadri, S., Schellenberg, G. D., Amouyel, P. & Williams, J., Dec 1 2015, In: Brain. 138, 12, p. 3673-3684 12 p.

    Research output: Contribution to journalArticlepeer-review

    158 Scopus citations
  • Common variation in COL4A1/COL4A2 is associated with sporadic cerebral small vessel disease

    METASTROKE Consortium, CHARGE WMH Group, ISGC ICH GWAS Study Collaboration, WMH in Ischemic Stroke GWAS Study Collaboration & International Stroke Genetics Consortium, Mar 3 2015, In: Neurology. 84, 9, p. 918-926 9 p.

    Research output: Contribution to journalArticlepeer-review

    71 Scopus citations
  • Convergent genetic and expression data implicate immunity in Alzheimer's disease

    International Genomics of Alzheimer's Disease Consortium (IGAP), Jun 1 2015, In: Alzheimer's and Dementia. 11, 6, p. 658-671 14 p.

    Research output: Contribution to journalArticlepeer-review

    120 Scopus citations
  • Diagnostic value of lobar microbleeds in individuals without intracerebral hemorrhage

    Martinez-Ramirez, S., Romero, J. R., Shoamanesh, A., McKee, A. C., Van Etten, E., Pontes-Neto, O., Macklin, E. A., Ayres, A., Auriel, E., Himali, J. J., Beiser, A. S., Decarli, C., Stein, T. D., Alvarez, V. E., Frosch, M. P., Rosand, J., Greenberg, S. M., Gurol, M. E., Seshadri, S. & Viswanathan, A., Dec 1 2015, In: Alzheimer's and Dementia. 11, 12, p. 1480-1488 9 p.

    Research output: Contribution to journalArticlepeer-review

    81 Scopus citations
  • Directional dominance on stature and cognition in diverse human populations

    The Bio Bank Japan Project, Jul 23 2015, In: Nature. 523, 7561, p. 459-462 4 p.

    Research output: Contribution to journalArticlepeer-review

    89 Scopus citations
  • Gender and incidence of dementia in the Framingham Heart Study from mid-adult life

    Chêne, G., Beiser, A., Au, R., Preis, S. R., Wolf, P. A., Dufouil, C. & Seshadri, S., Mar 1 2015, In: Alzheimer's and Dementia. 11, 3, p. 310-320 11 p.

    Research output: Contribution to journalArticlepeer-review

    128 Scopus citations
  • Genes from a translational analysis support a multifactorial nature of white matter hyperintensities

    Lopez, L. M., Hill, W. D., Harris, S. E., Valdes Hernandez, M., Munoz Maniega, S., Bastin, M. E., Bailey, E., Smith, C., McBride, M., McClure, J., Graham, D., Dominiczak, A., Yang, Q., Fornage, M., Ikram, M. A., Debette, S., Launer, L., Bis, J. C., Schmidt, R., Seshadri, S. & 4 others, Porteous, D. J., Starr, J., Deary, I. J. & Wardlaw, J. M., Feb 6 2015, In: Stroke. 46, 2, p. 341-347 7 p.

    Research output: Contribution to journalArticlepeer-review

    22 Scopus citations
  • Genetic contributions to variation in general cognitive function: A meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949)

    Davies, G., Armstrong, N., Bis, J. C., Bressler, J., Chouraki, V., Giddaluru, S., Hofer, E., Ibrahim-Verbaas, C. A., Kirin, M., Lahti, J., Van Der Lee, S. J., Le Hellard, S., Liu, T., Marioni, R. E., Oldmeadow, C., Postmus, I., Smith, A. V., Smith, J. A., Thalamuthu, A., Thomson, R. & 109 others, Vitart, V., Wang, J., Yu, L., Zgaga, L., Zhao, W., Boxall, R., Harris, S. E., Hill, W. D., Liewald, D. C., Luciano, M., Adams, H., Ames, D., Amin, N., Amouyel, P., Assareh, A. A., Au, R., Becker, J. T., Beiser, A., Berr, C., Bertram, L., Boerwinkle, E., Buckley, B. M., Campbell, H., Corley, J., De Jager, P. L., Dufouil, C., Eriksson, J. G., Espeseth, T., Faul, J. D., Ford, I., Scotland, G., Gottesman, R. F., Griswold, M. E., Gudnason, V., Harris, T. B., Heiss, G., Hofman, A., Holliday, E. G., Huffman, J., Kardia, S. L. R., Kochan, N., Knopman, D. S., Kwok, J. B., Lambert, J. C., Lee, T., Li, G., Li, S. C., Loitfelder, M., Lopez, O. L., Lundervold, A. J., Lundqvist, A., Mather, K. A., Mirza, S. S., Nyberg, L., Oostra, B. A., Palotie, A., Papenberg, G., Pattie, A., Petrovic, K., Polasek, O., Psaty, B. M., Redmond, P., Reppermund, S., Rotter, J. I., Schmidt, H., Schuur, M., Schofield, P. W., Scott, R. J., Steen, V. M., Stott, D. J., Van Swieten, J. C., Taylor, K. D., Trollor, J., Trompet, S., Uitterlinden, A. G., Weinstein, G., Widen, E., Windham, B. G., Jukema, J. W., Wright, A. F., Wright, M. J., Yang, Q., Amieva, H., Attia, J. R., Bennett, D. A., Brodaty, H., De Craen, A. J. M., Hayward, C., Ikram, M. A., Lindenberger, U., Nilsson, L. G., Porteous, D. J., Räikkönen, K., Reinvang, I., Rudan, I., Sachdev, P. S., Schmidt, R., Schofield, P. R., Srikanth, V., Starr, J. M., Turner, S. T., Weir, D. R., Wilson, J. F., Van Duijn, C., Launer, L., Fitzpatrick, A. L., Seshadri, S., Mosley, T. H. & Deary, I. J., Feb 1 2015, In: Molecular psychiatry. 20, 2, p. 183-192 10 p.

    Research output: Contribution to journalArticlepeer-review

    201 Scopus citations
  • Genetic Factors Influencing Coagulation Factor XIII B-Subunit Contribute to Risk of Ischemic Stroke

    METASTROKE Consortium & Wellcome Trust Case Control Consortium 2, Aug 1 2015, In: Stroke; a journal of cerebral circulation. 46, 8, p. 2069-2074 6 p.

    Research output: Contribution to journalArticlepeer-review

    14 Scopus citations
  • Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus

    Desikan, R. S., Schork, A. J., Wang, Y., Witoelar, A., Sharma, M., McEvoy, L. K., Holland, D., Brewer, J. B., Chen, C. H., Thompson, W. K., Harold, D., Williams, J., Owen, M. J., O'Donovan, M. C., Pericak-Vance, M. A., Mayeux, R., Haines, J. L., Farrer, L. A., Schellenberg, G. D., Heutink, P. & 25 others, Singleton, A. B., Brice, A., Wood, N. W., Hardy, J., Martinez, M., Choi, S. H., Destefano, A., Ikram, M. A., Bis, J. C., Smith, A., Fitzpatrick, A. L., Launer, L., Van Duijn, C., Seshadri, S., Ulstein, I. D., Aarsland, D., Fladby, T., Djurovic, S., Hyman, B. T., Snaedal, J., Stefansson, H., Stefansson, K., Gasser, T., Andreassen, O. A. & Dale, A. M., Dec 1 2015, In: Molecular psychiatry. 20, 12, p. 1588-1595 8 p.

    Research output: Contribution to journalArticlepeer-review

    84 Scopus citations
  • Genetic overlap between diagnostic subtypes of ischemic stroke

    Holliday, E. G., Traylor, M., Malik, R., Bevan, S., Falcone, G., Hopewell, J. C., Cheng, Y. C., Cotlarciuc, I., Bis, J. C., Boerwinkle, E., Boncoraglio, G. B., Clarke, R., Cole, J. W., Fornage, M., Furie, K. L., Ikram, M. A., Jannes, J., Kittner, S. J., Lincz, L. F., Maguire, J. M. & 20 others, Meschia, J. F., Mosley, T. H., Nalls, M. A., Oldmeadow, C., Parati, E. A., Psaty, B. M., Rothwell, P. M., Seshadri, S., Scott, R. J., Sharma, P., Sudlow, C., Wiggins, K. L., Worrall, B. B., Rosand, J., Mitchell, B. D., Dichgans, M., Markus, H. S., Levi, C., Attia, J. & Wray, N. R., Mar 1 2015, In: Stroke. 46, 3, p. 615-619 5 p.

    Research output: Contribution to journalArticlepeer-review

    28 Scopus citations
  • Genetic studies of body mass index yield new insights for obesity biology

    Lifelines Cohort Study & ADIPOGen Consortium; AGEN-BMI Working Group; CARDIOGRAMplusC4D Consortium; CKDGen Consortium; GLGC; ICBP; MAGIC Investigators; MuTHER Consortium; MIGen Consortium; PAGE Consortium; ReproGen Consortium; GENIE Consortium; International Endogene Consortium, Feb 12 2015, In: Nature. 518, 7538, p. 197-206 10 p.

    Research output: Contribution to journalArticlepeer-review

    2006 Scopus citations
  • Genome-wide studies of verbal declarative memory in nondemented older people: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium

    Cohorts for Heart and Aging Research in Genomic Epidemiology consortium, 2015, In: Biological Psychiatry. 77, 8, p. 749-763 15 p.

    Research output: Contribution to journalArticlepeer-review

    43 Scopus citations
  • Glucose indices are associated with cognitive and structural brain measures in young adults

    Weinstein, G., Maillard, P., Himali, J. J., Beiser, A. S., Au, R., Wolf, P. A., Seshadri, S. & Decarli, C., Jun 9 2015, In: Neurology. 84, 23, p. 2329-2337 9 p.

    Research output: Contribution to journalArticlepeer-review

    64 Scopus citations
  • GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy

    Broer, L., Buchman, A. S., Deelen, J., Evans, D. S., Faul, J. D., Lunetta, K. L., Sebastiani, P., Smith, J. A., Smith, A. V., Tanaka, T., Yu, L., Arnold, A. M., Aspelund, T., Benjamin, E. J., De Jager, P. L., Eirkisdottir, G., Evans, D. A., Garcia, M. E., Hofman, A., Kaplan, R. C. & 27 others, Kardia, S. L. R., Kiel, D. P., Oostra, B. A., Orwoll, E. S., Parimi, N., Psaty, B. M., Rivadeneira, F., Rotter, J. I., Seshadri, S., Singleton, A., Tiemeier, H., Uitterlinden, A. G., Zhao, W., Bandinelli, S., Bennett, D. A., Ferrucci, L., Gudnason, V., Harris, T. B., Karasik, D., Launer, L. J., Perls, T. T., Eline Slagboom, P., Tranah, G. J., Weir, D. R., Newman, A. B., Van Duijn, C. M. & Murabito, J. M., Jan 1 2015, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 70, 1, p. 110-118 9 p.

    Research output: Contribution to journalArticlepeer-review

    157 Scopus citations
  • Hepatic steatosis and cardiovascular disease outcomes: An analysis of the Framingham Heart Study

    Mellinger, J. L., Pencina, K. M., Massaro, J. M., Hoffmann, U., Seshadri, S., Fox, C. S., O'Donnell, C. J. & Speliotes, E. K., 2015, In: Journal of Hepatology. 63, 2, p. 470-476 7 p.

    Research output: Contribution to journalArticlepeer-review

    103 Scopus citations
  • Inflammatory biomarkers, cerebral microbleeds, and small vessel disease: Framingham heart study

    Shoamanesh, A., Preis, S. R., Beiser, A. S., Vasan, R. S., Benjamin, E. J., Kase, C. S., Wolf, P. A., DeCarli, C., Romero, J. R. & Seshadri, S., Feb 24 2015, In: Neurology. 84, 8, p. 825-832 8 p.

    Research output: Contribution to journalArticlepeer-review

    111 Scopus citations
  • Job strain and cognitive decline: A prospective study of the framingham offspring cohort

    Agbenyikey, W., Karasek, R., Cifuentes, M., Wolf, P. A., Seshadri, S., Taylor, J. A., Beiser, A. S. & Au, R., 2015, In: International Journal of Occupational and Environmental Medicine. 6, 2, p. 79-94 16 p.

    Research output: Contribution to journalArticlepeer-review

    17 Scopus citations
  • Lipid and lipoprotein measurements and the risk of ischemic vascular events: Framingham Study

    Pikula, A., Beiser, A. S., Wang, J., Himali, J. J., Kelly-Hayes, M., Kase, C. S., Yang, Q., Seshadri, S. & Wolf, P. A., 2015, In: Neurology. 84, 5, p. 472-479 8 p.

    Research output: Contribution to journalArticlepeer-review

    37 Scopus citations
  • Long-Term Exposure to Fine Particulate Matter, Residential Proximity to Major Roads and Measures of Brain Structure

    Wilker, E. H., Preis, S. R., Beiser, A. S., Wolf, P. A., Au, R., Kloog, I., Li, W., Schwartz, J., Koutrakis, P., Decarli, C., Seshadri, S. & Mittleman, M. A., May 20 2015, In: Stroke. 46, 5, p. 1161-1166 6 p.

    Research output: Contribution to journalArticlepeer-review

    119 Scopus citations
  • Low Cardiac index is associated with incident dementia and alzheimer disease: The framingham heart study

    Jefferson, A. L., Beiser, A. S., Himali, J. J., Seshadri, S., O'Donnell, C. J., Manning, W. J., Wolf, P. A., Au, R. & Benjamin, E. J., 2015, In: Circulation. 131, 15, p. 1333-1339 7 p.

    Research output: Contribution to journalArticlepeer-review

    88 Scopus citations
  • Mid-life cardiovascular risk impacts memory function

    Gupta, A., Preis, S. R., Beiser, A., Devine, S., Hankee, L., Seshadri, S., Wolf, P. A. & Au, R., Jun 9 2015, In: Alzheimer Disease and Associated Disorders. 29, 2, p. 117-123 7 p.

    Research output: Contribution to journalArticlepeer-review

    11 Scopus citations
  • Midlife Hypertension Risk and Cognition in the Non-Demented Oldest Old: Framingham Heart Study

    Nishtala, A., Himali, J. J., Beiser, A., Murabito, J. M., Seshadri, S., Wolf, P. A. & Au, R., 2015, In: Journal of Alzheimer's Disease. 47, 1, p. 197-204 8 p.

    Research output: Contribution to journalArticlepeer-review

    8 Scopus citations
  • Multiethnic Genome-Wide Association Study of Cerebral White Matter Hyperintensities on MRI

    Verhaaren, B. F. J., Debette, S., Bis, J. C., Smith, J. A., Ikram, M. K., Adams, H. H., Beecham, A. H., Rajan, K. B., Lopez, L. M., Barral, S., Van Buchem, M. A., Van Der Grond, J., Smith, A. V., Hegenscheid, K., Aggarwal, N. T., De Andrade, M., Atkinson, E. J., Beekman, M., Beiser, A. S., Blanton, S. H. & 82 others, Boerwinkle, E., Brickman, A. M., Bryan, R. N., Chauhan, G., Chen, C. P. L. H., Chouraki, V., De Craen, A. J. M., Crivello, F., Deary, I. J., Deelen, J., De Jager, P. L., Dufouil, C., Elkind, M. S. V., Evans, D. A., Freudenberger, P., Gottesman, R. F., Gunason, V., Habes, M., Heckbert, S. R., Heiss, G., Hilal, S., Hofer, E., Hofman, A., Ibrahim-Verbaas, C. A., Knopman, D. S., Lewis, C. E., Liao, J., Liewald, D. C. M., Luciano, M., Van Der Lugt, A., Martinez, O. O., Mayeux, R., Mazoyer, B., Nalls, M., Nauck, M., Niessen, W. J., Oostra, B. A., Psaty, B. M., Rice, K. M., Rotter, J. I., Von Sarnowski, B., Schmidt, H., Schreiner, P. J., Schuur, M., Sidney, S. S., Sigurdsson, S., Slagboom, P. E., Stott, D. J. M., Van Swieten, J. C., Teumer, A., Töglhofer, A. M., Traylor, M., Trompet, S., Turner, S. T., Tzourio, C., Uh, H. W., Uitterlinden, A. G., Vernooij, M. W., Wang, J. J., Wong, T. Y., Wardlaw, J. M., Windham, B. G., Wittfeld, K., Wolf, C., Wright, C. B., Yang, Q., Zhao, W., Zijdenbos, A., Jukema, J. W., Sacco, R. L., Kardia, S. L. R., Amouyel, P., Mosley, T. H., Longstreth, W. T., DeCarli, C. C., Van Duijn, C. M., Schmidt, R., Launer, L. J., Grabe, H. J., Seshadri, S. S., Ikram, M. A. & Fornage, M., Apr 4 2015, In: Circulation: Cardiovascular Genetics. 8, 2, p. 398-409 12 p.

    Research output: Contribution to journalArticlepeer-review

    105 Scopus citations
  • New genetic loci link adipose and insulin biology to body fat distribution

    ADIPOGen Consortium; CARDIOGRAMplusC4D Consortium; CKDGen Consortium; GEFOS Consortium; GENIE Consortium; GLGC; ICBP; International Endogene Consortium; LifeLines Cohort Study; MAGIC Investigators; MuTHER Consortium; PAGE Consortium; ReproGen Consortium, Feb 12 2015, In: Nature. 518, 7538, p. 187-196 10 p.

    Research output: Contribution to journalArticlepeer-review

    689 Scopus citations
  • No additional prognostic value of genetic information in the prediction of vascular events after cerebral ischemia of arterial origin: The PROMISe study

    SMART Study Group & METASTROKE Consortium, Apr 23 2015, In: PloS one. 10, 4, e0119203.

    Research output: Contribution to journalArticlepeer-review

    4 Scopus citations
  • Normative Data for the Cognitively Intact Oldest-Old: The Framingham Heart Study

    Miller, I. N., Himali, J. J., Beiser, A. S., Murabito, J. M., Seshadri, S., Wolf, P. A. & Au, R., Aug 8 2015, In: Experimental Aging Research. 41, 4, p. 386-409 24 p.

    Research output: Contribution to journalArticlepeer-review

    12 Scopus citations
  • Plasma amyloid-β and risk of Alzheimer's disease in the Framingham Heart Study

    Chouraki, V., Beiser, A., Younkin, L., Preis, S. R., Weinstein, G., Hansson, O., Skoog, I., Lambert, J. C., Au, R., Launer, L., Wolf, P. A., Younkin, S. & Seshadri, S., Mar 1 2015, In: Alzheimer's and Dementia. 11, 3, p. 249-257.e1

    Research output: Contribution to journalArticlepeer-review

    51 Scopus citations
  • PLD3 variants in population studies

    Van Der Lee, S. J., Holstege, H., Wong, T. H., Jakobsdottir, J., Bis, J. C., Chouraki, V., Van Rooij, J. G. J., Grove, M. L., Smith, A. V., Amin, N., Choi, S. H., Beiser, A. S., Garcia, M. E., Van IJcken, W. F. J., Pijnenburg, Y. A. L., Louwersheimer, E., Brouwer, R. W. W., Van Den Hout, M. C. G. N., Oole, E., Eirkisdottir, G. & 18 others, Levy, D., Rotter, J. I., Emilsson, V., O'Donnell, C. J., Aspelund, T., Uitterlinden, A. G., Launer, L. J., Hofman, A., Boerwinkle, E., Psaty, B. M., DeStefano, A. L., Scheltens, P., Seshadri, S., Van Swieten, J. C., Gudnason, V., Van Der Flier, W. M., Ikram, M. A. & Van Duijn, C. M., Apr 2 2015, In: Nature. 520, 7545, p. E2-E3

    Research output: Contribution to journalArticlepeer-review

    39 Scopus citations
  • Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease

    Desikan, R. S., Schork, A. J., Wang, Y., Thompson, W. K., Dehghan, A., Ridker, P. M., Chasman, D. I., Mcevoy, L. K., Holland, D., Chen, C. H., Karow, D. S., Brewer, J. B., Hess, C. P., Williams, J., Sims, R., O'donovan, M. C., Choi, S. H., Bis, J. C., Ikram, M. A., Gudnason, V. & 27 others, Destefano, A. L., Van Der Lee, S. J., Psaty, B. M., Van Duijn, C. M., Launer, L., Seshadri, S., Pericak-Vance, M. A., Mayeux, R., Haines, J. L., Farrer, L. A., Hardy, J., Ulstein, I. D., Aarsland, D., Fladby, T., White, L. R., Sando, S. B., Rongve, A., Witoelar, A., Djurovic, S., Hyman, B. T., Snaedal, J., Steinberg, S., Stefansson, H., Stefansson, K., Schellenberg, G. D., Andreassen, O. A. & Dale, A. M., 2015, In: Circulation. 131, 23, p. 2061-2069 9 p.

    Research output: Contribution to journalArticlepeer-review

    70 Scopus citations
  • Rare and coding region genetic variants associated with risk of ischemic stroke: The NHLBI Exome Sequence Project

    Auer, P. L., Nalls, M., Meschia, J. F., Worrall, B. B., Longstreth, W. T., Seshadri, S., Kooperberg, C., Burger, K. M., Carlson, C. S., Carty, C. L., Chen, W. M., Cupples, L. A., DeStefano, A. L., Fornage, M., Hardy, J., Hsu, L., Jackson, R. D., Jarvik, G. P., Kim, D. S., Lakshminarayan, K. & 8 others, Lange, L. A., Manichaikul, A., Quinlan, A. R., Singleton, A. B., Thornton, T. A., Nickerson, D. A., Peters, U. & Rich, S. S., Jul 1 2015, In: JAMA Neurology. 72, 7, p. 781-788 8 p.

    Research output: Contribution to journalArticlepeer-review

    32 Scopus citations
  • Serum leptin levels and the risk of stroke: The framingham study

    Saber, H., Himali, J. J., Shoamanesh, A., Beiser, A., Pikula, A., Harris, T. B., Roubenoff, R., Romero, J. R., Kase, C. S., Vasan, R. S. & Seshadri, S., Sep 3 2015, In: Stroke. 46, 10, p. 2881-2885 5 p.

    Research output: Contribution to journalArticlepeer-review

    16 Scopus citations
  • Shared genetic basis for migraine and ischemic stroke

    Malik, R., Freilinger, T., Winsvold, B. S., Anttila, V., Vander Heiden, J., Traylor, M., De Vries, B., Holliday, E. G., Terwindt, G. M., Sturm, J., Bis, J. C., Hopewell, J. C., Ferrari, M. D., Rannikmae, K., Wessman, M., Kallela, M., Kubisch, C., Fornage, M., Meschia, J. F., Lehtimäki, T. & 33 others, Sudlow, C., Clarke, R., Chasman, D. I., Mitchell, B. D., Maguire, J., Kaprio, J., Farrall, M., Raitakari, O. T., Kurth, T., Ikram, M. A., Reiner, A. P., Longstreth, W. T., Rothwell, P. M., Strachan, D. P., Sharma, P., Seshadri, S., Quaye, L., Cherkas, L., Schürks, M., Rosand, J., Ligthart, L., Boncoraglio, G. B., Davey Smith, G., Van Duijn, C. M., Stefansson, K., Worrall, B. B., Nyholt, D. R., Markus, H. S., Van Den Maagdenberg, A. M. J. M., Cotsapas, C., Zwart, J. A., Palotie, A. & Dichgans, M., May 26 2015, In: Neurology. 84, 21, p. 2132-2145 14 p.

    Research output: Contribution to journalArticlepeer-review

    56 Scopus citations
  • Structural Brain MRI Trait Polygenic Score Prediction of Cognitive Abilities

    Generation Scotland & The CHARGE Consortium, Dec 1 2015, In: Twin Research and Human Genetics. 18, 6, p. 738-745 8 p.

    Research output: Contribution to journalArticlepeer-review

    2 Scopus citations
  • Validation of secondary data sources to identify parkinson disease against clinical diagnostic criteria

    Jain, S., Himali, J., Beiser, A., Ton, T. G. N., Kelly-Hayes, M., Biggs, M. L., Delaney, J. A. C., Rosano, C., Seshadri, S. & Frank, S. A., Feb 1 2015, In: American journal of epidemiology. 181, 3, p. 185-190 6 p.

    Research output: Contribution to journalArticlepeer-review

    11 Scopus citations
  • Verbal memory and brain aging: An exploratory analysis of the role of error responses in the Framingham study

    Libon, D. J., Preis, S. R., Beiser, A. S., Devine, S., Seshadri, S., Wolf, P. A., DeCarli, C. & Au, R., Sep 13 2015, In: American Journal of Alzheimer's Disease and other Dementias. 30, 6, p. 622-628 7 p.

    Research output: Contribution to journalArticlepeer-review

    2 Scopus citations
  • White Matter Lesion Progression: Genome-Wide Search for Genetic Influences

    Hofer, E., Cavalieri, M., Bis, J. C., DeCarli, C., Fornage, M., Sigurdsson, S., Srikanth, V., Trompet, S., Verhaaren, B. F. J., Wolf, C., Yang, Q., Adams, H. H. H., Amouyel, P., Beiser, A., Buckley, B. M., Callisaya, M., Chauhan, G., De Craen, A. J. M., Dufouil, C., Van Duijn, C. M. & 40 others, Ford, I., Freudenberger, P., Gottesman, R. F., Gudnason, V., Heiss, G., Hofman, A., Lumley, T., Martinez, O., Mazoyer, B., Moran, C., Niessen, W. J., Phan, T., Psaty, B. M., Satizabal, C. L., Sattar, N., Schilling, S., Shibata, D. K., Slagboom, P. E., Smith, A., Stott, D. J., Taylor, K. D., Thomson, R., Töglhofer, A. M., Tzourio, C., Van Buchem, M., Wang, J., Westendorp, R. G. J., Gwen Windham, B., Vernooij, M. W., Zijdenbos, A., Beare, R., Debette, S., Ikram, M. A., Jukema, J. W., Launer, L. J., Longstreth, W. T., Mosley, T. H., Seshadri, S., Schmidt, H. & Schmidt, R., Nov 1 2015, In: Stroke. 46, 11, p. 3048-3057 10 p.

    Research output: Contribution to journalArticlepeer-review

    18 Scopus citations
  • 2014

    Allelic differences between Europeans and Chinese for CREB1 SNPs and their implications in gene expression regulation, hippocampal structure and function, and bipolar disorder susceptibility

    Li, M., Luo, X. J., Rietschel, M., Lewis, C. M., Mattheisen, M., Müller-Myhsok, B., Jamain, S., Leboyer, M., Landén, M., Thompson, P. M., Cichon, S., Nöthen, M. M., Schulze, T. G., Sullivan, P. F., Bergen, S. E., Donohoe, G., Morris, D. W., Hargreaves, A., Gill, M., Corvin, A. & 28 others, Hultman, C., Toga, A. W., Shi, L., Lin, Q., Shi, H., Gan, L., Meyer-Lindenberg, A., Czamara, D., Henry, C., Etain, B., Bis, J. C., Ikram, M. A., Fornage, M., Debette, S., Launer, L. J., Seshadri, S., Erk, S., Walter, H., Heinz, A., Bellivier, F., Stein, J. L., Medland, S. E., Arias Vasquez, A., Hibar, D. P., Franke, B., Martin, N. G., Wright, M. J. & Su, B., Apr 2014, In: Molecular psychiatry. 19, 4, p. 452-461 10 p.

    Research output: Contribution to journalArticlepeer-review

    40 Scopus citations
  • Association between neuropathology and brain volume in the framingham heart study

    Kaur, B., Himali, J. J., Seshadri, S., Beiser, A. S., Au, R., McKee, A. C., Auerbach, S., Wolf, P. A. & Decarli, C. S., 2014, In: Alzheimer Disease and Associated Disorders. 28, 3, p. 219-225 7 p.

    Research output: Contribution to journalArticlepeer-review

    17 Scopus citations
  • Associations of NINJ2 sequence variants with incident ischemic stroke in the Cohorts for Heart and Aging in Genomic Epidemiology (CHARGE) consortium

    Bis, J. C., DeStefano, A., Liu, X., Brody, J. A., Choi, S. H., Verhaaren, B. F. J., Debette, S., Ikram, M. A., Shahar, E., Butler, K. R., Gottesman, R. F., Muzny, D., Kovar, C. L., Psaty, B. M., Hofman, A., Lumley, T., Gupta, M., Wolf, P. A., Van Duijn, C., Gibbs, R. A. & 5 others, Mosley, T. H., Longstreth, W. T., Boerwinkle, E., Seshadri, S. & Fornage, M., Jun 24 2014, In: PloS one. 9, 6, e99798.

    Research output: Contribution to journalArticlepeer-review

    6 Scopus citations
  • ATP5H/KCTD2 locus is associated with Alzheimer's disease risk

    Boada, M., Antúnez, C., Ramírez-Lorca, R., Destefano, A. L., González-Pérez, A., Gayán, J., López-Arrieta, J., Ikram, M. A., Hernández, I., Marín, J., Galán, J. J., Bis, J. C., Mauleón, A., Rosende-Roca, M., Moreno-Rey, C., Gudnasson, V., Morón, F. J., Velasco, J., Carrasco, J. M., Alegret, M. & 16 others, Espinosa, A., Vinyes, G., Lafuente, A., Vargas, L., Fitzpatrick, A. L., Launer, L. J., Sáez, M. E., Vázquez, E., Becker, J. T., López, O. L., Serrano-Ríos, M., Tárraga, L., Van Duijn, C. M., Real, L. M., Seshadri, S. & Ruiz, A., Jun 2014, In: Molecular psychiatry. 19, 6, p. 682-687 6 p.

    Research output: Contribution to journalArticlepeer-review

    41 Scopus citations
  • Cognitive performance after stroke - The Framingham Heart Study

    Weinstein, G., Preis, S. R., Beiser, A. S., Au, R., Kelly-Hayes, M., Kase, C. S., Wolf, P. A. & Seshadri, S., Oct 1 2014, In: International Journal of Stroke. 9, A100, p. 48-54 7 p.

    Research output: Contribution to journalArticlepeer-review

    19 Scopus citations
  • Development and validation of a brief dementia screening indicator for primary care

    Barnes, D. E., Beiser, A. S., Lee, A., Langa, K. M., Koyama, A., Preis, S. R., Neuhaus, J., McCammon, R. J., Yaffe, K., Seshadri, S., Haan, M. N. & Weir, D. R., Nov 1 2014, In: Alzheimer's and Dementia. 10, 6, p. 656-665.e1

    Research output: Contribution to journalArticlepeer-review

    51 Scopus citations
  • Follow-up of loci from the International Genomics of Alzheimer's Disease Project identifies TRIP4 as a novel susceptibility gene

    Ruiz, A., Heilmann, S., Becker, T., Hernández, I., Wagner, H., Thelen, M., Mauleón, A., Rosende-Roca, M., Bellenguez, C., Bis, J. C., Harold, D., Gerrish, A., Sims, R., Sotolongo-Grau, O., Espinosa, A., Alegret, M., Arrieta, J. L., Lacour, A., Leber, M., Becker, J. & 24 others, Lafuente, A., Ruiz, S., Vargas, L., Rodríguez, O., Ortega, G., Dominguez, M. A., Mayeux, R., Haines, J. L., Pericak-Vance, M. A., Farrer, L. A., Schellenberg, G. D., Chouraki, V., Launer, L. J., Van Duijn, C., Seshadri, S., Antúnez, C., Breteler, M. M., Serrano-Ríos, M., Jessen, F., Tárraga, L., Nöthen, M. M., Maier, W., Boada, M. & Ramírez, A. L., 2014, In: Translational psychiatry. 4, 20142.

    Research output: Contribution to journalArticlepeer-review

    57 Scopus citations
  • Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease

    Escott-Price, V., Bellenguez, C., Wang, L. S., Choi, S. H., Harold, D., Jones, L., Holmans, P., Gerrish, A., Vedernikov, A., Richards, A., DeStefano, A. L., Lambert, J. C., Ibrahim-Verbaas, C. A., Naj, A. C., Sims, R., Jun, G., Bis, J. C., Beecham, G. W., Grenier-Boley, B., Russo, G. & 167 others, Thornton-Wells, T. A., Denning, N., Smith, A. V., Chouraki, V., Thomas, C., Arfan Ikram, M., Zelenika, D., Vardarajan, B. N., Kamatani, Y., Lin, C. F., Schmidt, H., Kunkle, B., Dunstan, M. L., Vronskaya, M., Johnson, A. D., Ruiz, A., Bihoreau, M. T., Reitz, C., Pasquier, F., Hollingworth, P., Hanon, O., Fitzpatrick, A. L., Buxbaum, J. D., Campion, D., Crane, P. K., Becker, C. B. T., Gudnason, V., Cruchaga, C., Craig, D., Amin, N., Berr, C., Lopez, O. L., De Jager, P. L., Deramecourt, V., Johnston, J. A., Evans, D., Lovestone, S., Letenneur, L., Hernández, I., Rubinsztein, D. C., Eiriksdottir, G., Sleegers, K., Goate, A. M., Fiévet, N., Huentelman, M. J., Gill, M., Brown, K., Kamboh, M. I., Keller, L., Barberger-Gateau, P., McGuinness, B., Larson, E. B., Myers, A. J., Dufouil, C., Todd, S., Wallon, D., Love, S., Rogaeva, E., Gallacher, J., St George-Hyslop, P., Clarimon, J., Lleo, A., Bayer, A., Tsuang, D. W., Yu, L., Tsolaki, M., Bossù, P., Spalletta, G., Proitsi, P., Collinge, J., Sorbi, S., Sanchez Garcia, F., Fox, N. C., Hardy, J., Naranjo, M. C. D., Bosco, P., Clarke, R., Brayne, C., Galimberti, D., Scarpini, E., Bonuccelli, U., Mancuso, M., Siciliano, G., Moebus, S., Mecocci, P., Del Zompo, M., Maier, W., Hampel, H., Pilotto, A., Frank-García, A., Panza, F., Solfrizzi, V., Caffarra, P., Nacmias, B., Perry, W., Mayhaus, M., Lannfelt, L., Hakonarson, H., Pichler, S., Carrasquillo, M. M., Ingelsson, M., Beekly, D., Alvarez, V., Zou, F., Valladares, O., Younkin, S. G., Coto, E., Hamilton-Nelson, K. L., Gu, W., Razquin, C., Pastor, P., Mateo, I., Owen, M. J., Faber, K. M., Jonsson, P. V., Combarros, O., O'Donovan, M. C., Cantwell, L. B., Soininen, H., Blacker, D., Mead, S., Mosley, T. H., Bennett, D. A., Harris, T. B., Fratiglioni, L., Holmes, C., De Bruijn, R. F. A. G., Passmore, P., Montine, T. J., Bettens, K., Rotter, J. I., Brice, A., Morgan, K., Foroud, T. M., Kukull, W. A., Hannequin, D., Powell, J. F., Nalls, M. A., Ritchie, K., Lunetta, K. L., Kauwe, J. S. K., Boerwinkle, E., Riemenschneider, M., Boada, M., Hiltunen, M., Martin, E. R., Schmidt, R., Rujescu, D., Dartigues, J. F., Mayeux, R., Tzourio, C., Hofman, A., Nöthen, M. M., Graff, C., Psaty, B. M., Haines, J. L., Lathrop, M., Pericak-Vance, M. A., Launer, L. J., Van Broeckhoven, C., Farrer, L. A., Van Duijn, C. M., Ramirez, A., Seshadri, S., Schellenberg, G. D., Amouyel, P. & Williams, J., Jun 12 2014, In: PloS one. 9, 6, e94661.

    Research output: Contribution to journalArticlepeer-review

    70 Scopus citations
  • Genome-wide association study of l-arginine and dimethylarginines reveals novel metabolic pathway for symmetric dimethylarginine

    Lüneburg, N., Lieb, W., Zeller, T., Chen, M. H., Maas, R., Carter, A. M., Xanthakis, V., Glazer, N. L., Schwedhelm, E., Seshadri, S., Ikram, M. A., Longstreth, W. T., Fornage, M., König, I. R., Loley, C., Ojeda, F. M., Schillert, A., Wang, T. J., Sticht, H., Kittel, A. & 24 others, König, J., Benjamin, E. J., Sullivan, L. M., Bernges, I., Anderssohn, M., Ziegler, A., Gieger, C., Illig, T., Meisinger, C., Wichmann, H. E., Wild, P. S., Schunkert, H., Psaty, B. M., Wiggins, K. L., Heckbert, S. R., Smith, N., Lackner, K., Lunetta, K. L., Blankenberg, S., Erdmann, J., Munzel, T., Grant, P. J., Vasan, R. S. & Böger, R. H., Dec 1 2014, In: Circulation: Cardiovascular Genetics. 7, 6, p. 864-872 9 p.

    Research output: Contribution to journalArticlepeer-review

    37 Scopus citations
  • Genome-Wide Meta-Analysis of Homocysteine and Methionine Metabolism Identifies Five One Carbon Metabolism Loci and a Novel Association of ALDH1L1 with Ischemic Stroke

    Williams, S. R., Yang, Q., Chen, F., Liu, X., Keene, K. L., Jacques, P., Chen, W. M., Weinstein, G., Hsu, F. C., Beiser, A., Wang, L., Bookman, E., Doheny, K. F., Wolf, P. A., Zilka, M., Selhub, J., Nelson, S., Gogarten, S. M., Worrall, B. B., Seshadri, S. & 1 others, Sale, M. M., Mar 2014, In: PLoS Genetics. 10, 3, e1004214.

    Research output: Contribution to journalArticlepeer-review

    54 Scopus citations