Steven R Seidner

  • 1532 Citations
  • 24 h-Index
1982 …2020

Research output per year

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Research Output

  • 1532 Citations
  • 24 h-Index
  • 65 Article
  • 1 Chapter
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Article
2020

Oxygen and mechanical ventilation impede the functional properties of resident lung mesenchymal stromal cells

Moreira, A. G., Siddiqui, S. K., Macias, R., Johnson-Pais, T. L., Wilson, D., Gelfond, J. A. L., Vasquez, M. M., Seidner, S. R. & Mustafa, S. B., 2020, In : PloS one. 15, 3, e0229521.

Research output: Contribution to journalArticle

Open Access
2018

Effects of antenatal betamethasone on preterm human and mouse ductus arteriosus: comparison with baboon data

Shelton, E. L., Waleh, N., Plosa, E. J., Benjamin, J. T., Milne, G. L., Hooper, C. W., Ehinger, N. J., Poole, S., Brown, N., Seidner, S., McCurnin, D., Reese, J. & Clyman, R. I., Sep 1 2018, In : Pediatric Research. 84, 3, p. 458-465 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Effects of intravenous AICAR (5- aminoimidazole-4-carboximide riboside) administration on insulin signaling and resistance in premature baboons, Papio sp

Blanco, C. L., Gastaldelli, A., Anzueto, D. G., Winter, L. A., Seidner, S. R., McCurnin, D. C., Liang, H., Javors, M. A., DeFronzo, R. A. & Musi, N., Dec 2018, In : PloS one. 13, 12, e0208757.

Research output: Contribution to journalArticle

1 Scopus citations
2017

Hepatic insulin resistance and altered gluconeogenic pathway in premature baboons

McGill-Vargas, L., Gastaldelli, A., Liang, H., Guerra, D. A., Johnson-Pais, T., Seidner, S., McCurnin, D., Muscogiuri, G., DeFronzo, R., Musi, N. & Blanco, C., May 1 2017, In : Endocrinology. 158, 5, p. 1140-1151 12 p.

Research output: Contribution to journalArticle

2 Scopus citations
2015

Peripheral insulin resistance and impaired insulin signaling contribute to abnormal glucose metabolism in preterm baboons

Blanco, C. L., McGill-Vargas, L. L., Gastaldelli, A., Seidner, S. R., McCurnin, D. C., Leland, M. M., Anzueto, D. G., Johnson, M. C., Liang, H., DeFronzo, R. A. & Musi, N., Mar 1 2015, In : Endocrinology. 156, 3, p. 813-823 11 p.

Research output: Contribution to journalArticle

11 Scopus citations
2014

Mechanical stretch induces lung α-epithelial Na+channel expression

Mustafa, S. B., Isaac, J., Seidner, S. R., Dixon, P. S., Henson, B. M. & Digeronimo, R. J., Oct 1 2014, In : Experimental Lung Research. 40, 8, p. 380-391 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

Neonatal intubation with direct laryngoscopy vs videolaryngoscopy: An extremely premature baboon model

Moreira, A., Koele-Schmidt, L., Leland, M., Seidner, S. & Blanco, C., Aug 2014, In : Paediatric Anaesthesia. 24, 8, p. 840-844 5 p.

Research output: Contribution to journalArticle

2 Scopus citations
2013

Smad7 inhibits autocrine expression of TGF-β2 in intestinal epithelial cells in baboon necrotizing enterocolitis

Namachivayam, K., Blanco, C. L., Mohankumar, K., Jagadeeswaran, R., Vasquez, M., Mcgill-Vargas, L., Garzon, S. A., Jain, S. K., Gill, R. K., Freitag, N. E., Weitkamp, J. H., Seidner, S. R. & Maheshwari, A., Jan 15 2013, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 304, 2, p. G167-G180

Research output: Contribution to journalArticle

32 Scopus citations
2012

Effects of ibuprofen treatment on the developing preterm baboon kidney

Sutherland, M. R., Yoder, B. A., McCurnin, D., Seidner, S., Gubhaju, L., Clyman, R. I. & Jane Black, M., May 15 2012, In : American Journal of Physiology - Renal Physiology. 302, 10, p. F1286-F1292

Research output: Contribution to journalArticle

39 Scopus citations
2011

Anatomic closure of the premature patent ductus arteriosus: The role of CD14 +/CD163 + mononuclear cells and vegf in neointimal mound formation

Waleh, N., Seidner, S., McCurnin, D., Giavedoni, L., Hodara, V., Goelz, S., Liu, B. M., Roman, C. & Clyman, R. I., Oct 2011, In : Pediatric Research. 70, 4, p. 332-338 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

Neonatal chlamydial pneumonia induces altered respiratory structure and function lasting into adult life

Jupelli, M., Murthy, A. K., Chaganty, B. K. R., Guentzel, M. N., Selby, D. M., Vasquez, M. M., Mustafa, S. B., Henson, B. M., Seidner, S. R., Zhong, G. & Arulanandam, B. P., Oct 1 2011, In : Laboratory Investigation. 91, 10, p. 1530-1539 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

Relationship between circulating platelet counts and ductus arteriosus patency after indomethacin treatment

Shah, N. A., Hills, N. K., Waleh, N., McCurnin, D., Seidner, S., Chemtob, S. & Clyman, R., Jun 2011, In : Journal of Pediatrics. 158, 6, p. 919-923.e2

Research output: Contribution to journalArticle

33 Scopus citations
2010

Patterns of gene expression in the ductus arteriosus are related to environmental and genetic risk factors for persistent ductus patency

Waleh, N., Hodnick, R., Jhaveri, N., McConaghy, S., Dagle, J., Seidner, S., McCurnin, D., Murray, J. C., Ohls, R. & Clyman, R. I., Oct 2010, In : Pediatric Research. 68, 4, p. 292-297 6 p.

Research output: Contribution to journalArticle

28 Scopus citations
2009

Oxygen-induced tension in the sheep ductus arteriosus: Effects of gestation on potassium and calcium channel regulation

Waleh, N., Reese, J., Kajino, H., Roman, C., Seidner, S., McCurnin, D. & Clyman, R. I., Mar 2009, In : Pediatric Research. 65, 3, p. 285-290 6 p.

Research output: Contribution to journalArticle

23 Scopus citations

Regulation of epithelial Na+ channel (ENaC) in the salivary cell line SMG-C6

Vasquez, M. M., Mustafa, S. B., Choudary, A., Seidner, S. R. & Castro, R., May 1 2009, In : Experimental Biology and Medicine. 234, 5, p. 522-531 10 p.

Research output: Contribution to journalArticle

10 Scopus citations
2008

Ibuprofen-induced patent ductus arteriosus closure: Physiologic, histologic, and biochemical effects on the premature lung

McCurnin, D., Seidner, S., Chang, L. Y., Waleh, N., Ikegami, M., Petershack, J., Yoder, B., Giavedoni, L., Albertine, K. H., Dahl, M. J., Wang, Z. M. & Clyman, R. I., May 2008, In : Pediatrics. 121, 5, p. 945-956 12 p.

Research output: Contribution to journalArticle

61 Scopus citations

Induction of serum- and glucocorticoid-induced kinase-1 (SGK1) by cAMP regulates increases in α-ENaC

Vasquez, M. M., Castro, R., Seidner, S. R., Henson, B. M., Ashton, D. J. & Mustafa, S. B., Dec 1 2008, In : Journal of Cellular Physiology. 217, 3, p. 632-642 11 p.

Research output: Contribution to journalArticle

18 Scopus citations

Protein kinase A and mitogen-activated protein kinase pathways mediate cAMP induction of α-epithelial Na+ channels (α-ENaC)

Mustafa, S. B., Castro, R., Falck, A. J., Petershack, J. A., Henson, B. M., Mendoza, Y. M., Choudary, A. & Seidner, S. R., Apr 1 2008, In : Journal of Cellular Physiology. 215, 1, p. 101-110 10 p.

Research output: Contribution to journalArticle

24 Scopus citations
2007

Mechanical ventilation down-regulates surfactant protein A and keratinocyte growth factor expression in premature rabbits

DiGeronimo, R. J., Mustafa, S. B., Ryan, R. M., Sternberg, Z. Z., Ashton, D. J. & Seidner, S. R., Sep 1 2007, In : Pediatric Research. 62, 3, p. 277-282 6 p.

Research output: Contribution to journalArticle

15 Scopus citations
2006

Postnatal constriction, ATP depletion, and cell death in the mature and immature ductus arteriosus

Levin, M., McCurnin, D., Seidner, S. R., Yoder, B., Waleh, N., Goldbarg, S., Roman, C., Liu, B. M., Borén, J. & Clyman, R. I., Feb 2006, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 290, 2, p. R359-R364

Research output: Contribution to journalArticle

20 Scopus citations
2005

The role of monocyte-derived cells and inflammation in baboon ductus arteriosus remodeling

Waleh, N., Seidner, S., McCurnin, D., Yoder, B., Liu, B. M., Roman, C., Mauray, F. & Clyman, R. I., Feb 2005, In : Pediatric Research. 57, 2, p. 254-262 9 p.

Research output: Contribution to journalArticle

33 Scopus citations
2004
22 Scopus citations

Prenatal glucocorticoid exposure and postnatal adaptation in premature newborn baboons ventilated for six days

Smith, L. M., Altamirano, A. K., Ervin, M. G., Seidner, S. R. & Jobe, A. H., Nov 2004, In : American Journal of Obstetrics and Gynecology. 191, 5, p. 1688-1694 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Prostaglandin E2-mediated relaxation of the ductus arteriosus: Effects of gestational age on G protein-coupled receptor expression, signaling, and vasomotor control

Waleh, N., Kajino, H., Marrache, A. M., Ginzinger, D., Roman, C., Seidner, S. R., Moss, T. J. M., Fouron, J. C., Vazquez-Tello, A., Chemtob, S. & Clyman, R. I., Oct 19 2004, In : Circulation. 110, 16, p. 2326-2332 7 p.

Research output: Contribution to journalArticle

48 Scopus citations
2003

Adrenal and thyroid axis function in preterm ventilated baboons

Jobe, A. H., Scott, S. M., Polk, D. H. & Seidner, S. R., 2003, In : Biology of the Neonate. 83, 3, p. 208-216 9 p.

Research output: Contribution to journalArticle

3 Scopus citations
2002

Surfactant phosphatidylcholine half-life and pool size measurements in premature baboons developing bronchopulmonary dysplasia

Janssen, D. J. M. T., Carnielli, V. P., Cogo, P. E., Seidner, S. R., Luijendijk, I. H. I., Darcos Wattimena, J. L., Jobe, A. H. & Zimmermann, L. J. I., Nov 1 2002, In : Pediatric Research. 52, 5, p. 724-729 6 p.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations

VEGF regulates remodeling during permanent anatomic closure of the ductus arteriosus

Clyman, R. I., Seidner, S. R., Kajino, H., Roman, C., Koch, C. J., Ferrara, N., Waleh, N., Mauray, F., Chen, Y. Q., Perkett, E. A. & Quinn, T., 2002, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 282, 1 51-1, p. R199-R206

Research output: Contribution to journalArticle

43 Scopus citations
2001

Combined prostaglandin and nitric oxide inhibition produces anatomic remodeling and closure of the ductus arteriosus in the premature newborn baboon

Seidner, S. R., Chen, Y. Q., Oprysko, P. R., Mauray, F., Tse, M. M., Lin, E., Koch, C. & Clyman, R. I., 2001, In : Pediatric Research. 50, 3, p. 365-373 9 p.

Research output: Contribution to journalArticle

Open Access
67 Scopus citations

Factors that increase the contractile tone of the ductus arteriosus also regulate its anatomic remodeling

Kajino, H., Chen, Y. Q., Seidner, S. R., Waleh, N., Mauray, F., Roman, C., Chemtob, S., Koch, C. J. & Clyman, R. I., 2001, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 281, 1 50-1, p. R291-R301

Research output: Contribution to journalArticle

50 Scopus citations
1999

Effects of postnatal dexamethasone and exogenous surfactant on surfactant protein B mobilization in preterm rabbits

DiGeronimo, R. J., Welke, T. M., Segura-Jones, L. & Seidner, S. R., Feb 1999, In : Journal of Investigative Medicine. 47, 2, p. 142A

Research output: Contribution to journalArticle

Metabolism of endogenous surfactant in premature baboons and effect of prenatal corticosteroids

Bunt, J. E. H., Carnielli, V. P., Seidner, S. R., Ikegami, M., Wattimena, J. L. D., Sauer, P. J. J., Jobe, A. H. & Zimmermann, L. J. I., 1999, In : American Journal of Respiratory and Critical Care Medicine. 160, 5 I, p. 1481-1485 5 p.

Research output: Contribution to journalArticle

19 Scopus citations

Permanent anatomic closure of the ductus arteriosus in newborn baboons: The roles of postnatal constriction, hypoxia, and gestation

Clyman, R. I., Chan, C. Y., Mauray, F., Chen, Y. Q., Cox, W., Seidner, S. R., Lord, E. M., Weiss, H., Waleh, N., Evans, S. M. & Koch, C. J., Jan 1999, In : Pediatric Research. 45, 1, p. 19-29 11 p.

Research output: Contribution to journalArticle

Open Access
101 Scopus citations
1998

Abnormal surfactant metabolism and function in preterm ventilated baboons

Seidner, S. R., Jobe, A. H., Coalson, J. J. & Ikegami, M., 1998, In : American Journal of Respiratory and Critical Care Medicine. 158, 6, p. 1982-1989 8 p.

Research output: Contribution to journalArticle

41 Scopus citations
6 Scopus citations

Direct fetal glucocorticoid treatment alters postnatal adaptation in premature newborn baboons

Ervin, M. G., Seidner, S. R., Leland, M. M., Ikegami, M. & Jobe, A. H., Apr 1998, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 274, 4 43-4, p. R1169-R1176

Research output: Contribution to journalArticle

23 Scopus citations
1997

Effects of continuous bed rotation and prolonged mechanical ventilation on healthy, adult baboons

Anzueto, A., Peters, J. I., Seidner, S. R., Cox, W. J., Schroeder, W. & Coalson, J. J., Sep 26 1997, In : Critical care medicine. 25, 9, p. 1560-1564 5 p.

Research output: Contribution to journalArticle

29 Scopus citations
1996

Characterization of two baboon surfactant protein A genes

Gao, E., Wang, Y., Mccormick, S. M., Li, J., Seidner, S. R. & Mendelson, C. R., Oct 1996, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 271, 4 15-4, p. L617-L630

Research output: Contribution to journalArticle

28 Scopus citations

Developmental and hormonal regulation of SP-A gene expression in baboon fetal lung

Seidner, S. R., Smith, M. E. & Mendelson, C. R., Oct 1996, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 271, 4 15-4, p. L609-L616

Research output: Contribution to journalArticle

21 Scopus citations
1995

Decreased surfactant dose-response after delayed administration to preterm rabbits

Seidner, S. R., Ikegami, M., Yamada, T., Rider, E. D., Castro, R. & Jobe, A. H., Jul 1995, In : American Journal of Respiratory and Critical Care Medicine. 152, 1, p. 113-120 8 p.

Research output: Contribution to journalArticle

42 Scopus citations

SP-A deficiency in primate model of bronchopulmonary dysplasia with infection: In situ mRNA and immunostains

Coalson, J. J., King, R. J., Yang, F., Winter, V., Whitsett, J. A., Delemos, R. A. & Seidner, S. R., Mar 1995, In : American Journal of Respiratory and Critical Care Medicine. 151, 3 I, p. 854-866 13 p.

Research output: Contribution to journalArticle

53 Scopus citations

Surfactant protein-A deficiency in a primate model of bronchopulmonary dysplasia

King, R. J., Coalson, J. J., DeLemos, R. A., Gerstmann, D. R. & Seidner, S. R., Jun 1995, In : American Journal of Respiratory and Critical Care Medicine. 151, 6, p. 1989-1997 9 p.

Research output: Contribution to journalArticle

25 Scopus citations
1992

Effect of antenatal thyrotropin-releasing hormone, antenatal corticosteroids, and postnatal ventilation on surfactant mobilization in premature rabbits

Seidner, S., Rider, E., Jobe, A., Yamada, T. & Ikegami, M., May 1992, In : American Journal of Obstetrics and Gynecology. 166, 5, p. 1551-1559 9 p.

Research output: Contribution to journalArticle

12 Scopus citations
1990

Cumulative effects of repeated surfactant treatments in the rabbit

Pettenazzo, A., Jobe, A. H., Ikegami, M., Rider, E., Seidner, S. R. & Yamada, T., Jan 1 1990, In : Experimental Lung Research. 16, 2, p. 131-143 13 p.

Research output: Contribution to journalArticle

7 Scopus citations
1989

Effect of maternal hormone treatment on lung protein leakage and lung function of preterm newborn rabbits

Ikegami, M., Jobe, A., Pettenazzo, A. & Seidner, S., Jan 1 1989, In : European Respiratory Journal. 1, SUPPL. 3, p. 16s-20s

Research output: Contribution to journalArticle

6 Scopus citations

Gestational effects of corticosteroids and surfactant in preterm ventilated rabbits

Jobe, A. H., Ikegami, M., Seidner, S. & Yamada, T., Jan 1 1989, In : Fernstrom Foundation Series. 12, p. 221-226 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Gestational effects of corticosteroids and surfactant in ventilated rabbits

Ikegami, M., Jobe, A. H., Seidner, S. & Yamada, T., Jan 1989, In : Pediatric Research. 25, 1, p. 32-37 6 p.

Research output: Contribution to journalArticle

Open Access
41 Scopus citations

Recovery of treatment doses of surfactants from the lungs and vascular compartments of mechanically ventilated premature rabbits

Seidner, S. R., Jobe, A. H., Ruffini, L., Ikegami, M. & Pettenazzo, A., Apr 1989, In : Pediatric Research. 25, 4, p. 423-428 6 p.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations
21 Scopus citations