Research output per year
Research output per year
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Dive into the research topics where Shaun K Olsen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL
Nayak, D., Lv, D., Yuan, Y., Zhang, P., Hu, W., Nayak, A., Ruben, E. A., Lv, Z., Sung, P., Hromas, R., Zheng, G., Zhou, D. & Olsen, S. K., Dec 2024, In: Nature communications. 15, 1, 2743.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Characterization of the Ubiquitin and ISG15 Deconjugase Activity of SARS-CoV-1 and SARS-CoV-2 Papain-Like Protease
Nayak, D., dos Santos Bury, P., Drag, M., Nijkerk, A. N., El Oualid, F. & Olsen, S. K., 2023, Methods in Molecular Biology. Humana Press, p. 171-188 18 p. (Methods in Molecular Biology; vol. 2591).Research output: Chapter in Book/Report/Conference proceeding › Chapter
1 Scopus citations -
Cryo-EM structures of Uba7 reveal the molecular basis for ISG15 activation and E1-E2 thioester transfer
Afsar, M., Liu, G. Q., Jia, L., Ruben, E. A., Nayak, D., Sayyad, Z., Bury, P. D. S., Cano, K. E., Nayak, A., Zhao, X. R., Shukla, A., Sung, P., Wasmuth, E. V., Gack, M. U. & Olsen, S. K., Dec 2023, In: Nature communications. 14, 1, 4786.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Ebselen derivatives inhibit SARS-CoV-2 replication by inhibition of its essential proteins: PLpro and Mpro proteases, and nsp14 guanine N7-methyltransferase
Zmudzinski, M., Rut, W., Olech, K., Granda, J., Giurg, M., Burda-Grabowska, M., Kaleta, R., Zgarbova, M., Kasprzyk, R., Zhang, L., Sun, X., Lv, Z., Nayak, D., Kesik-Brodacka, M., Olsen, S. K., Weber, J., Hilgenfeld, R., Jemielity, J. & Drag, M., Dec 2023, In: Scientific reports. 13, 1, 9161.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Structural insights into BCDX2 complex function in homologous recombination
Rawal, Y., Jia, L., Meir, A., Zhou, S., Kaur, H., Ruben, E. A., Kwon, Y., Bernstein, K. A., Jasin, M., Taylor, A. B., Burma, S., Hromas, R., Mazin, A. V., Zhao, W., Zhou, D., Wasmuth, E. V., Greene, E. C., Sung, P. & Olsen, S. K., Jul 20 2023, In: Nature. 619, 7970, p. 640-649 10 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations
Datasets
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Structure of an E1-E2-ubiquitin thioester mimetic
Yuan, L. (Contributor), Lv, Z. (Contributor), Adams, M. J. (Contributor) & Olsen, S. K. (Contributor), Protein Data Bank (PDB), Apr 28 2021
DOI: 10.2210/pdb7K5J/pdb, https://www.wwpdb.org/pdb?id=pdb_00007k5j
Dataset
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Crystal Structures of the bispecific ubiquitin/FAT10 activating enzyme, Uba6
Yuan, L. (Contributor), Gao, F. (Contributor), Lv, Z. (Contributor), Nayak, D. (Contributor), Nayak, A. (Contributor), Santos Bury, P. D. (Contributor), Cano, K. E. (Contributor), Jia, L. (Contributor), Oleinik, N. (Contributor), Atilgan, F. C. (Contributor), Ogretmen, B. (Contributor), Williams, K. M. (Contributor), Davies, C. (Contributor), El Oualid, F. (Contributor), Wasmuth, E. V. (Contributor) & Olsen, S. K. (Contributor), Protein Data Bank (PDB), Nov 2 2022
DOI: 10.2210/pdb7SOL/pdb, https://www.wwpdb.org/pdb?id=pdb_00007sol
Dataset
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Cryo-EM structure of the human BCDX2 complex
Rawal, Y. (Contributor), Jia, L. (Contributor), Meir, A. (Contributor), Zhou, S. (Contributor), Kaur, H. (Contributor), Ruben, E. A. (Contributor), Kwon, Y. (Contributor), Bernstein, K. A. (Contributor), Jasin, M. (Contributor), Taylor, A. B. (Contributor), Burma, S. (Contributor), Hromas, R. (Contributor), Mazin, A. V. (Contributor), Zhao, W. (Contributor), Zhou, D. (Contributor), Wasmuth, E. V. (Contributor), Greene, E. C. (Contributor), Sung, P. (Contributor) & Olsen, S. K. (Contributor), Protein Data Bank (PDB), Jun 21 2023
DOI: 10.2210/pdb8FAZ/pdb, https://www.wwpdb.org/pdb?id=pdb_00008faz
Dataset
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Crystal structure of the SARS CoV-2 Papain-like protease in complex with peptide inhibitor VIR251
Rut, W. (Contributor), Lv, Z. (Contributor), Zmudzinski, M. (Contributor), Patchett, S. (Contributor), Nayak, D. (Contributor), Snipas, S. J. (Contributor), Oualid, F. E. (Contributor), Huang, T. T. (Contributor), Bekes, M. (Contributor), Drag, M. (Contributor) & Olsen, S. K. (Contributor), Protein Data Bank (PDB), May 20 2020
DOI: 10.2210/pdb6WX4/pdb, https://www.wwpdb.org/pdb?id=pdb_00006wx4
Dataset
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Cryo-EM structure of a human BCDX2/ssDNA complex
Rawal, Y. (Contributor), Jia, L. (Contributor), Meir, A. (Contributor), Zhou, S. (Contributor), Kaur, H. (Contributor), Ruben, E. A. (Contributor), Kwon, Y. (Contributor), Bernstein, K. A. (Contributor), Jasin, M. (Contributor), Taylor, A. B. (Contributor), Burma, S. (Contributor), Hromas, R. (Contributor), Mazin, A. V. (Contributor), Zhao, W. (Contributor), Zhou, D. (Contributor), Wasmuth, E. V. (Contributor), Greene, E. C. (Contributor), Sung, P. (Contributor) & Olsen, S. K. (Contributor), Protein Data Bank (PDB), Jun 21 2023
DOI: 10.2210/pdb8GBJ/pdb, https://www.wwpdb.org/pdb?id=pdb_00008gbj
Dataset