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Collaborations and top research areas from the last five years
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NF2 loss malignantly transforms human pancreatic acinar cells and enhances cell fitness under environmental stress
Xu, Y., Nipper, M. H., Dominguez, A. A., He, C., Sharkey, F. E., Khan, S., Xu, H., Zhou, D., Zheng, L., Luan, Y., Liu, J. & Wang, P., Jan 2 2026, In: The Journal of clinical investigation. 136, 1Research output: Contribution to journal › Article › peer-review
Open Access -
Discovery of PZ671, a highly potent and in vivo active CRBN-recruiting Bcl-xL degrader
Zhang, P., Thummuri, D., Hu, W., Khan, S., He, Y., Zhang, X., Pal, P., Lv, D., Zhou, D., Zheng, G. & Zhou, D., Aug 13 2025, In: RSC Medicinal Chemistry. 16, 8, p. 3495-3506 12 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Targeting DDR2 for Treating Pancreatic Cancer
Do, C. T. P., Venkata, P. P., Prochnau, J. Y., Singh, D., Timilsina, S., Subbarayalu, P., Medina, D., Abdulsahib, S., Nirzhor, S., Khan, S., Li, G., Polusani, S. R., Zhou, D., Wang, P., Chen, Y., Vadlamudi, R. K., Hart, M. J., Amaradhi, R., McHardy, S. F. & Rao, M. K., Oct 1 2025, In: Molecular cancer therapeutics. 24, 10, p. 1570-1583 14 p.Research output: Contribution to journal › Article › peer-review
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PROTAC-Mediated Dual Degradation of BCL-xL and BCL-2 Is a Highly Effective Therapeutic Strategy in Small-Cell Lung Cancer
Khan, S., Cao, L., Wiegand, J., Zhang, P., Zajac-Kaye, M., Kaye, F. J., Zheng, G. & Zhou, D., Mar 2024, In: Cells. 13, 6, 528.Research output: Contribution to journal › Article › peer-review
Open Access21 Link opens in a new tab Scopus citations -
Co-targeting BCL-XL and MCL-1 with DT2216 and AZD8055 synergistically inhibit small-cell lung cancer growth without causing on-target toxicities in mice
Khan, S., Kellish, P., Connis, N., Thummuri, D., Wiegand, J., Zhang, P., Zhang, X., Budamagunta, V., Hua, N., Yang, Y., De, U., Jin, L., Zhang, W., Zheng, G., Hromas, R., Hann, C., Zajac-Kaye, M., Kaye, F. J. & Zhou, D., Dec 2023, In: Cell Death Discovery. 9, 1, 1.Research output: Contribution to journal › Article › peer-review
Open Access33 Link opens in a new tab Scopus citations
Datasets
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Additional file 2 of Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies
He, Y. (Creator), Khan, S. (Creator), Huo, Z. (Creator), Lv, D. (Creator), Zhang, X. (Creator), Liu, X. (Creator), Yuan, Y. (Creator), Hromas, R. (Creator), Xu, M. (Creator), Zheng, G. (Creator) & Zhou, D. (Creator), Figshare, 2020
DOI: 10.6084/m9.figshare.12726547.v1, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_Proteolysis_targeting_chimeras_PROTACs_are_emerging_therapeutics_for_hematologic_malignancies/12726547/1
Dataset
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Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies
He, Y. (Creator), Khan, S. (Creator), Huo, Z. (Creator), Lv, D. (Creator), Zhang, X. (Creator), Liu, X. (Creator), Yuan, Y. (Creator), Hromas, R. (Creator), Xu, M. (Creator), Zheng, G. (Creator) & Zhou, D. (Creator), Figshare, 2020
DOI: 10.6084/m9.figshare.c.5075029.v1, https://springernature.figshare.com/collections/Proteolysis_targeting_chimeras_PROTACs_are_emerging_therapeutics_for_hematologic_malignancies/5075029/1
Dataset
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Additional file 3 of Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies
He, Y. (Creator), Khan, S. (Creator), Huo, Z. (Creator), Lv, D. (Creator), Zhang, X. (Creator), Liu, X. (Creator), Yuan, Y. (Creator), Hromas, R. (Creator), Xu, M. (Creator), Zheng, G. (Creator) & Zhou, D. (Creator), Figshare, 2020
DOI: 10.6084/m9.figshare.12726550, https://springernature.figshare.com/articles/dataset/Additional_file_3_of_Proteolysis_targeting_chimeras_PROTACs_are_emerging_therapeutics_for_hematologic_malignancies/12726550
Dataset
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Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies
He, Y. (Creator), Khan, S. (Creator), Huo, Z. (Creator), Lv, D. (Creator), Zhang, X. (Creator), Liu, X. (Creator), Yuan, Y. (Creator), Hromas, R. (Creator), Xu, M. (Creator), Zheng, G. (Creator) & Zhou, D. (Creator), Figshare, 2020
DOI: 10.6084/m9.figshare.c.5075029, https://springernature.figshare.com/collections/Proteolysis_targeting_chimeras_PROTACs_are_emerging_therapeutics_for_hematologic_malignancies/5075029
Dataset
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Additional file 3 of Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies
He, Y. (Creator), Khan, S. (Creator), Huo, Z. (Creator), Lv, D. (Creator), Zhang, X. (Creator), Liu, X. (Creator), Yuan, Y. (Creator), Hromas, R. (Creator), Xu, M. (Creator), Zheng, G. (Creator) & Zhou, D. (Creator), Figshare, 2020
DOI: 10.6084/m9.figshare.12726550.v1, https://springernature.figshare.com/articles/dataset/Additional_file_3_of_Proteolysis_targeting_chimeras_PROTACs_are_emerging_therapeutics_for_hematologic_malignancies/12726550/1
Dataset