Robert Brenner — Scholars @ UT Health San Antonio

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Projects 2007 2016

2 Finished

SK channel antagonists as novel bronchodilators for asthma

Brenner, R.

National Institutes of Health

7/1/14 → 6/30/16

Project: Research project › Exploratory/Developmental Grants

Bronchodilator Agents

Asthma

Smooth Muscle

Small-Conductance Calcium-Activated Potassium Channels

Research

BK Channel B4 Subunit in the Dentate Gyrus and Seizures

Brenner, R.

National Institutes of Health

4/1/07 → 3/31/13

Project: Research project › Research Project

Large-Conductance Calcium-Activated Potassium Channels

Dentate Gyrus

Seizures

Knockout Mice

Genetic Models

Research Output 1988 2018

2975 Citations
21 h-Index
42 Article

A computational model for how the fast afterhyperpolarization paradoxically increases gain in regularly firing neurons

Jaffe, D. B. & Brenner, R., Apr 1 2018, In : Journal of Neurophysiology. 119, 4, p. 1506-1520 15 p.

Research output: Contribution to journal › Article

Action Potentials

Large-Conductance Calcium-Activated Potassium Channels

Neurons

Dentate Gyrus

Carisoprodol

2 Citations

Cataract-associated connexin 46 mutation alters its interaction with calmodulin and function of hemichannels

Hu, Z., Riquelme, M. A., Wang, B., Bugay, V., Brenner, R., Gu, S. & Jiang, J. X., Jan 1 2018, In : Journal of Biological Chemistry. 293, 7, p. 2573-2585 13 p.

Research output: Contribution to journal › Article

Calmodulin

Cataract

Substitution reactions

Mutation

Permeability

13 Citations

Nanoparticle delivery of CRISPR into the brain rescues a mouse model of fragile X syndrome from exaggerated repetitive behaviours

Lee, B., Lee, K., Panda, S., Gonzales-Rojas, R., Chong, A., Bugay, V., Park, H. M., Brenner, R., Murthy, N. & Lee, H. Y., Jun 25 2018, (Accepted/In press) In : Nature Biomedical Engineering. p. 1-11 11 p.

Research output: Contribution to journal › Article

Clustered Regularly Interspaced Short Palindromic Repeats

Fragile X Syndrome

Nanoparticles

Brain

Gold

Voltage effects on muscarinic acetylcholine receptor-mediated contractions of airway smooth muscle

Semenov, I. & Brenner, R., Sep 1 2018, In : Physiological Reports. 6, 17, e13856.

Research output: Contribution to journal › Article

Muscarinic Receptors

Smooth Muscle

Membrane Potentials

Cholinergic Agents

Muscarinic M3 Receptors

12 Citations

Adiponectin regulates contextual fear extinction and intrinsic excitability of dentate gyrus granule neurons through AdipoR2 receptors

Zhang, D., Wang, X., Wang, B., Garza, J. C., Fang, X., Wang, J., Scherer, P. E., Brenner, R., Zhang, W. & Lu, X. Y., Jul 1 2017, In : Molecular Psychiatry. 22, 7, p. 1044-1055 12 p.

Research output: Contribution to journal › Article

Adiponectin

Dentate Gyrus

Fear

Neurons

Post-Traumatic Stress Disorders