Robert Brenner

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3 Similar Profiles

Large-Conductance Calcium-Activated Potassium Channels Medicine & Life Sciences

Calcium-Activated Potassium Channels Medicine & Life Sciences

Smooth Muscle Medicine & Life Sciences

Neurons Medicine & Life Sciences

Drosophila Medicine & Life Sciences

Dentate Gyrus Medicine & Life Sciences

Action Potentials Medicine & Life Sciences

Mutation Medicine & Life Sciences

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Projects 2007 2016

2 Finished

SK channel antagonists as novel bronchodilators for asthma

Brenner, R.

National Institutes of Health

7/1/14 → 6/30/16

Project: Research project

Bronchodilator Agents

Asthma

Smooth Muscle

Small-Conductance Calcium-Activated Potassium Channels

Research

BK Channel B4 Subunit in the Dentate Gyrus and Seizures

Brenner, R.

National Institutes of Health

4/1/07 → 3/31/13

Project: Research project

Large-Conductance Calcium-Activated Potassium Channels

Dentate Gyrus

Seizures

Knockout Mice

Genetic Models

Research Output 1988 2019

3074 Citations
23 h-Index
44 Article
1 Chapter

Prevention of brain damage after traumatic brain injury by pharmacological enhancement of KCNQ (Kv7, “M-type”) K⁺ currents in neurons

Vigil, F. A., Bozdemir, E., Bugay, V., Chun, S. H., Hobbs, M. A., Sanchez, I., Hastings, S. D., Veraza, R. J., Holstein, D. M., Sprague, S. M., M Carver, C., Cavazos, J. E., Brenner, R., Lechleiter, J. D. & Shapiro, M. S., Jan 1 2019, In : Journal of Cerebral Blood Flow and Metabolism.

Research output: Contribution to journal › Article

Pharmacology

Neurons

Brain

Physiological Stress

Seizures

2 Citations (Scopus)

A computational model for how the fast afterhyperpolarization paradoxically increases gain in regularly firing neurons

Jaffe, D. B. & Brenner, R., Apr 1 2018, In : Journal of Neurophysiology. 119, 4, p. 1506-1520 15 p.

Research output: Contribution to journal › Article

Action Potentials

Large-Conductance Calcium-Activated Potassium Channels

Neurons

Dentate Gyrus

Carisoprodol

4 Citations (Scopus)

Cataract-associated connexin 46 mutation alters its interaction with calmodulin and function of hemichannels

Hu, Z., Riquelme, M. A., Wang, B., Bugay, V., Brenner, R., Gu, S. & Jiang, J. X., Jan 1 2018, In : Journal of Biological Chemistry. 293, 7, p. 2573-2585 13 p.

Research output: Contribution to journal › Article

Calmodulin

Cataract

Substitution reactions

Mutation

Permeability

32 Citations (Scopus)

Nanoparticle delivery of CRISPR into the brain rescues a mouse model of fragile X syndrome from exaggerated repetitive behaviours

Lee, B., Lee, K., Panda, S., Gonzales-Rojas, R., Chong, A., Bugay, V., Park, H. M., Brenner, R., Murthy, N. & Lee, H. Y., Jun 25 2018, (Accepted/In press) In : Nature Biomedical Engineering. p. 1-11 11 p.

Research output: Contribution to journal › Article

Clustered Regularly Interspaced Short Palindromic Repeats

Fragile X Syndrome

Nanoparticles

Brain

Metabotropic Glutamate 5 Receptor