Robert Brenner

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3 Similar Profiles

Large-Conductance Calcium-Activated Potassium Channels Medicine & Life Sciences

Calcium-Activated Potassium Channels Medicine & Life Sciences

Smooth Muscle Medicine & Life Sciences

Neurons Medicine & Life Sciences

Drosophila Medicine & Life Sciences

Dentate Gyrus Medicine & Life Sciences

Action Potentials Medicine & Life Sciences

Mutation Medicine & Life Sciences

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Projects 2007 2016

2 Finished

SK channel antagonists as novel bronchodilators for asthma

Brenner, R.

National Institutes of Health

7/1/14 → 6/30/16

Project: Research project

Bronchodilator Agents

Asthma

Smooth Muscle

Small-Conductance Calcium-Activated Potassium Channels

Research

BK Channel B4 Subunit in the Dentate Gyrus and Seizures

Brenner, R.

National Institutes of Health

4/1/07 → 3/31/13

Project: Research project

Large-Conductance Calcium-Activated Potassium Channels

Dentate Gyrus

Seizures

Knockout Mice

Genetic Models

Research Output 1988 2020

3123 Citations
24 h-Index
45 Article
1 Chapter

A Mouse Model of Repetitive Blast Traumatic Brain Injury Reveals Post-Trauma Seizures and Increased Neuronal Excitability

Bugay, V., Bozdemir, E., Vigil, F. A., Chun, S. H., Holstein, D. M., Elliott, W. R., Sprague, C. J., Cavazos, J. E., Zamora, D. O., Rule, G., Shapiro, M. S., Lechleiter, J. D. & Brenner, R., Jan 15 2020, In : Journal of Neurotrauma. 37, 2, p. 248-261 14 p.

Research output: Contribution to journal › Article

Seizures

Brain Concussion

Wounds and Injuries

Parahippocampal Gyrus

Partial Epilepsy

1 Citation (Scopus)

Prevention of brain damage after traumatic brain injury by pharmacological enhancement of KCNQ (Kv7, “M-type”) K⁺ currents in neurons

Vigil, F. A., Bozdemir, E., Bugay, V., Chun, S. H., Hobbs, M. A., Sanchez, I., Hastings, S. D., Veraza, R. J., Holstein, D. M., Sprague, S. M., M Carver, C., Cavazos, J. E., Brenner, R., Lechleiter, J. D. & Shapiro, M. S., Jan 1 2019, In : Journal of Cerebral Blood Flow and Metabolism.

Research output: Contribution to journal › Article

Pharmacology

Neurons

Brain

Physiological Stress

Seizures

2 Citations (Scopus)

A computational model for how the fast afterhyperpolarization paradoxically increases gain in regularly firing neurons

Jaffe, D. B. & Brenner, R., Apr 1 2018, In : Journal of Neurophysiology. 119, 4, p. 1506-1520 15 p.

Research output: Contribution to journal › Article

Action Potentials

Large-Conductance Calcium-Activated Potassium Channels

Neurons

Dentate Gyrus

Carisoprodol

4 Citations (Scopus)

Cataract-associated connexin 46 mutation alters its interaction with calmodulin and function of hemichannels

Hu, Z., Riquelme, M. A., Wang, B., Bugay, V., Brenner, R., Gu, S. & Jiang, J. X., Jan 1 2018, In : Journal of Biological Chemistry. 293, 7, p. 2573-2585 13 p.

Research output: Contribution to journal › Article

Calmodulin

Cataract

Substitution reactions

Mutation

Permeability

44 Citations (Scopus)

Nanoparticle delivery of CRISPR into the brain rescues a mouse model of fragile X syndrome from exaggerated repetitive behaviours

Lee, B., Lee, K., Panda, S., Gonzales-Rojas, R., Chong, A., Bugay, V., Park, H. M., Brenner, R., Murthy, N. & Lee, H. Y., Jun 25 2018, (Accepted/In press) In : Nature Biomedical Engineering. p. 1-11 11 p.

Research output: Contribution to journal › Article

Clustered Regularly Interspaced Short Palindromic Repeats

Fragile X Syndrome

Nanoparticles

Brain

Metabotropic Glutamate 5 Receptor