Robert Brenner

  • 2951 Citations
  • 21 h-Index
1988 …2018
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Large-Conductance Calcium-Activated Potassium Channels Medicine & Life Sciences
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Dentate Gyrus Medicine & Life Sciences
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Large-Conductance Calcium-Activated Potassium Channel beta Subunits Medicine & Life Sciences

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Projects 2007 2016

SK channel antagonists as novel bronchodilators for asthma

Brenner, R.

National Institutes of Health

7/1/146/30/16

Project: Research projectExploratory/Developmental Grants

Bronchodilator Agents
Asthma
Smooth Muscle
Small-Conductance Calcium-Activated Potassium Channels
Research

BK Channel B4 Subunit in the Dentate Gyrus and Seizures

Brenner, R.

National Institutes of Health

4/1/073/31/13

Project: Research projectResearch Project

Large-Conductance Calcium-Activated Potassium Channels
Dentate Gyrus
Seizures
Knockout Mice
Genetic Models

Research Output 1988 2018

  • 2951 Citations
  • 21 h-Index
  • 42 Article

A computational model for how the fast afterhyperpolarization paradoxically increases gain in regularly firing neurons

Jaffe, D. B. & Brenner, R., Apr 1 2018, In : Journal of Neurophysiology. 119, 4, p. 1506-1520 15 p.

Research output: Contribution to journalArticle

Action Potentials
Large-Conductance Calcium-Activated Potassium Channels
Neurons
Dentate Gyrus
Carisoprodol
2 Citations

Cataract-associated connexin 46 mutation alters its interaction with calmodulin and function of hemichannels

Hu, Z., Riquelme, M. A., Wang, B., Bugay, V., Brenner, R., Gu, S. & Jiang, J. X., Jan 1 2018, In : Journal of Biological Chemistry. 293, 7, p. 2573-2585 13 p.

Research output: Contribution to journalArticle

Calmodulin
Cataract
Substitution reactions
Mutation
Permeability
10 Citations

Nanoparticle delivery of CRISPR into the brain rescues a mouse model of fragile X syndrome from exaggerated repetitive behaviours

Lee, B., Lee, K., Panda, S., Gonzales-Rojas, R., Chong, A., Bugay, V., Park, H. M., Brenner, R., Murthy, N. & Lee, H. Y., Jun 25 2018, (Accepted/In press) In : Nature Biomedical Engineering. p. 1-11 11 p.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Fragile X Syndrome
Nanoparticles
Brain
Gold

Voltage effects on muscarinic acetylcholine receptor-mediated contractions of airway smooth muscle

Semenov, I. & Brenner, R., Sep 1 2018, In : Physiological Reports. 6, 17, e13856.

Research output: Contribution to journalArticle

Muscarinic Receptors
Smooth Muscle
Membrane Potentials
Cholinergic Agents
Muscarinic M3 Receptors
10 Citations

Adiponectin regulates contextual fear extinction and intrinsic excitability of dentate gyrus granule neurons through AdipoR2 receptors

Zhang, D., Wang, X., Wang, B., Garza, J. C., Fang, X., Wang, J., Scherer, P. E., Brenner, R., Zhang, W. & Lu, X. Y., Jul 1 2017, In : Molecular Psychiatry. 22, 7, p. 1044-1055 12 p.

Research output: Contribution to journalArticle

Adiponectin
Dentate Gyrus
Fear
Neurons
Post-Traumatic Stress Disorders

Press/Media

CRISPR reduces autism symptoms in mice

Robert Brenner & Hye Young Lee

6/25/187/11/18

5 items of media coverage

Press/Media: Press / Media

CRISPR editing reduces repetitive behavior in mice with a form of autism

Robert Brenner & Hye Young Lee

6/25/186/28/18

4 items of media coverage

Press/Media: Press / Media

Gene Editing Curbs Autism Symptoms in Mice

Hye Young Lee & Robert Brenner

6/26/186/28/18

3 items of media coverage

Press/Media: Press / Media

Gene editing curbs autism symptoms in mice

Robert Brenner & Hye Young Lee

6/26/18

1 item of media coverage

Press/Media: Press / Media

CRISPR Reduces Autism Symptoms in Mice

Robert Brenner & Hye Young Lee

6/25/18

1 item of media coverage

Press/Media: Press / Media