Robert A Hromas

Professor, Dean, Long School of Medicine

  • 7934 Citations
  • 47 h-Index
1980 …2019
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DNA Repair Medicine & Life Sciences
DNA Medicine & Life Sciences
Transposases Medicine & Life Sciences
Chemokines Medicine & Life Sciences
Repair Chemical Compounds
Zinc Fingers Medicine & Life Sciences
Genes Medicine & Life Sciences
Proteins Medicine & Life Sciences

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Research Output 1980 2019

DNA requirement in FANCD2 deubiquitination by USP1-UAF1-RAD51AP1 in the Fanconi anemia DNA damage response

Liang, F., Miller, A. S., Longerich, S., Tang, C., Maranon, D., Williamson, E. A., Hromas, R. A., Wiese, C., Kupfer, G. M. & Sung, P., Dec 1 2019, In : Nature communications. 10, 1, 2849.

Research output: Contribution to journalArticle

Open Access
anemias
Fanconi Anemia
DNA Damage
deoxyribonucleic acid
damage

MiR223-3p promotes synthetic lethality in BRCA1-deficient cancers

Srinivasan, G., Williamson, E. A., Kong, K., Jaiswal, A. S., Huang, G., Kim, H. S., Schärer, O., Zhao, W., Burma, S., Sung, P. & Hromas, R. A., Aug 27 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 35, p. 17438-17443 6 p.

Research output: Contribution to journalArticle

Open Access
BRCA1 Protein
Genetic Translocation
DNA End-Joining Repair
Neoplasms
Homologous Recombination

Radiation-induced DNA damage cooperates with heterozygosity of TP53 and PTEN to generate high-grade gliomas

Todorova, P. K., Fletcher-Sananikone, E., Mukherjee, B., Kollipara, R., Vemireddy, V., Xie, X. J., Guida, P. M., Story, M. D., Hatanpaa, K., Habib, A. A., Kittler, R., Bachoo, R., Hromas, R. A., Floyd, J. R. & Burma, S., Jan 1 2019, In : Cancer Research. 79, 14, p. 3749-3761 13 p.

Research output: Contribution to journalArticle

Glioma
DNA Damage
Radiation
Linear Energy Transfer
Neoplasms
2 Citations (Scopus)

The BRCA tumor suppressor network in chromosome damage repair by homologous recombination

Zhao, W., Wiese, C., Kwon, Y., Hromas, R. A. & Sung, P., Jun 20 2019, In : Annual Review of Biochemistry. 88, p. 221-245 25 p.

Research output: Contribution to journalReview article

Recombinational DNA Repair
Chromosomes
Tumors
Repair
Genes

A DNA nick at Ku-blocked double-strand break ends serves as an entry site for exonuclease 1 (Exo1) or Sgs1–Dna2 in long-range DNA end resection

Wang, W., Daley, J. M., Kwon, Y., Xue, X., Krasner, D. S., Miller, A. S., Nguyen, K. A., Williamson, E. A., Shim, E., Lee, S., Hromas, R. A. & Sung, P., Jan 1 2018, In : Journal of Biological Chemistry. 293, 44, p. 17061-17069 9 p.

Research output: Contribution to journalArticle

Single-Stranded DNA Breaks
DNA
Replication Protein A
DNA Breaks
Double-Stranded DNA Breaks