Robert A Hromas

Liang, F., Miller, A. S., Longerich, S., Tang, C., Maranon, D., Williamson, E. A., Hromas, R. A., Wiese, C., Kupfer, G. M. & Sung, P., Dec 1 2019, In : Nature communications. 10, 1, 2849.

Research output: Contribution to journal › Article

Open Access

anemias

Fanconi Anemia

DNA Damage

deoxyribonucleic acid

damage

1 Citation (Scopus)

MiR223-3p promotes synthetic lethality in BRCA1-deficient cancers

Srinivasan, G., Williamson, E. A., Kong, K., Jaiswal, A. S., Huang, G., Kim, H. S., Schärer, O., Zhao, W., Burma, S., Sung, P. & Hromas, R. A., Aug 27 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 35, p. 17438-17443 6 p.

Research output: Contribution to journal › Article

Open Access

BRCA1 Protein

Genetic Translocation

DNA End-Joining Repair

Neoplasms

Homologous Recombination

2 Citations (Scopus)

Radiation-induced DNA damage cooperates with heterozygosity of TP53 and PTEN to generate high-grade gliomas

Todorova, P. K., Fletcher-Sananikone, E., Mukherjee, B., Kollipara, R., Vemireddy, V., Xie, X. J., Guida, P. M., Story, M. D., Hatanpaa, K., Habib, A. A., Kittler, R., Bachoo, R., Hromas, R. A., Floyd, J. R. & Burma, S., Jan 1 2019, In : Cancer Research. 79, 14, p. 3749-3761 13 p.

Research output: Contribution to journal › Article

Glioma

DNA Damage

Radiation

Linear Energy Transfer

Neoplasms

4 Citations (Scopus)

The BRCA tumor suppressor network in chromosome damage repair by homologous recombination

Zhao, W., Wiese, C., Kwon, Y., Hromas, R. A. & Sung, P., Jun 20 2019, In : Annual Review of Biochemistry. 88, p. 221-245 25 p.

Research output: Contribution to journal › Review article

Recombinational DNA Repair

Chromosomes

Tumors

Repair

Genes

A DNA nick at Ku-blocked double-strand break ends serves as an entry site for exonuclease 1 (Exo1) or Sgs1–Dna2 in long-range DNA end resection

Wang, W., Daley, J. M., Kwon, Y., Xue, X., Krasner, D. S., Miller, A. S., Nguyen, K. A., Williamson, E. A., Shim, E., Lee, S., Hromas, R. A. & Sung, P., Jan 1 2018, In : Journal of Biological Chemistry. 293, 44, p. 17061-17069 9 p.

Research output: Contribution to journal › Article

Single-Stranded DNA Breaks

DNA

Replication Protein A

DNA Breaks

Double-Stranded DNA Breaks