Reuben Stewart Harris

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219 Article
17 Review article
7 Comment/debate
6 Chapter
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- 6 Short survey
- 2 Letter

APOBEC3 mutagenesis drives therapy resistance in breast cancer
Gupta, A., Gazzo, A., Selenica, P., Safonov, A., Pareja, F., da Silva, E. M., Brown, D. N., Shao, H., Zhu, Y., Patel, J., Blanco-Heredia, J., Stefanovska, B., Carpenter, M. A., Chen, Y., Vegas, I., Pei, X., Frosina, D., Jungbluth, A. A., Ladanyi, M. & Curigliano, G. & 8 others, Weigelt, B., Riaz, N., Powell, S. N., Razavi, P., Harris, R. S., Reis-Filho, J. S., Marra, A. & Chandarlapaty, S., Jun 2025, In: Nature Genetics. 57, 6, p. 1452-1462 11 p.
Research output: Contribution to journal › Article › peer-review

Open Access
17 Link opens in a new tab Scopus citations
APOBEC affects tumor evolution and age at onset of lung cancer in smokers
Zhang, T., Sang, J., Hoang, P. H., Zhao, W., Rosenbaum, J., Johnson, K. E., Klimczak, L. J., McElderry, J., Klein, A., Wirth, C., Bergstrom, E. N., Díaz-Gay, M., Vangara, R., Colon-Matos, F., Hutchinson, A., Lawrence, S. M., Cole, N., Zhu, B., Przytycka, T. M. & Shi, J. & 11 others, Caporaso, N. E., Homer, R., Pesatori, A. C., Consonni, D., Imielinski, M., Chanock, S. J., Wedge, D. C., Gordenin, D. A., Alexandrov, L. B., Harris, R. S. & Landi, M. T., Dec 2025, In: Nature communications. 16, 1, 4711.
Research output: Contribution to journal › Article › peer-review

Open Access
3 Link opens in a new tab Scopus citations
A split luciferase system for studying coronavirus M^pro dimerization in vitro and in living cells
Delgado, R., Vishwakarma, J., Sanlley Hernandez, J. O., Tansiongco, M., Cuell, A., Dabrowska, A., Basu, R., Schmidpeter, P. A. M., Hu, Y., Tsutakawa, S. E., Cooley, C. B., Amaro, R. E. & Harris, R. S., Dec 2025, In: Journal of Biological Chemistry. 301, 12, 110890.
Research output: Contribution to journal › Article › peer-review

Open Access
Azapeptide-Based SARS-CoV-2 Main Protease Inhibitors: Design, Synthesis, Enzyme Inhibition, Structural Determination, and Antiviral Activity
Flury, P., Vishwakarma, J., Sylvester, K., Higashi-Kuwata, N., Dabrowska, A. K., Delgado, R., Cuell, A., Basu, R., Taylor, A. B., de Oliveira, E. G., Magalhães Serafim, M. S., Qiao, J., Chen, Y., Yang, S., O’Donoghue, A. J., Mitsuya, H., Gütschow, M., Laufer, S. A., Müller, C. E. & Harris, R. S. & 1 others, Pillaiyar, T., Sep 25 2025, In: Journal of Medicinal Chemistry. 68, 18, p. 19339-19376 38 p.
Research output: Contribution to journal › Article › peer-review

Open Access
4 Link opens in a new tab Scopus citations
Differentiation signals induce APOBEC3A expression via GRHL3 in squamous epithelia and squamous cell carcinoma
Smith, N. J., Reddin, I., Policelli, P., Oh, S., Zainal, N., Howes, E., Jenkins, B., Tracy, I., Edmond, M., Sharpe, B., Amendra, D., Zheng, K., Egawa, N., Doorbar, J., Rao, A., Mahadevan, S., Carpenter, M. A., Harris, R. S., Ali, S. & Hanley, C. & 4 others, Buisson, R., King, E., Thomas, G. J. & Fenton, T. R., Jan 2 2025, In: EMBO Journal. 44, 1, p. 1-29 29 p., e1011043.
Research output: Contribution to journal › Article › peer-review

Open Access
3 Link opens in a new tab Scopus citations

Sars-Cov2 Main Protease in complex with CDD-1819
Jimmidi, R. (Contributor), Chamakuri, S. (Contributor), Lu, S. (Contributor), Ucisik, M. N. (Contributor), Chen, P.-J. (Contributor), Bohren, K. M. (Contributor), Moghadasi, S. A. (Contributor), Versteeg, L. (Contributor), Nnabuife, C. (Contributor), Li, J.-Y. (Contributor), Qin, X. (Contributor), Chen, Y.-C. (Contributor), Faver, J. C. (Contributor), Nyshadham, P. (Contributor), Sharma, K. L. (Contributor), Sankaran, B. (Contributor), Judge, A. (Contributor), Yu, Z. (Contributor), Li, F. (Contributor), Pollet, J. (Contributor), Harris, R. S. (Contributor), Matzuk, M. M. (Contributor), Palzkill, T. (Contributor) & Young, D. W. (Contributor), Protein Data Bank (PDB), Jul 26 2023
DOI: 10.2210/pdb7US4/pdb, https://www.wwpdb.org/pdb?id=pdb_00007us4
Dataset
SARS-Cov2 Main protease in complex with inhibitor CDD-1845
Jimmidi, R. (Contributor), Chamakuri, S. (Contributor), Lu, S. (Contributor), Ucisik, M. N. (Contributor), Chen, P.-J. (Contributor), Bohren, K. M. (Contributor), Moghadasi, S. A. (Contributor), Versteeg, L. (Contributor), Nnabuife, C. (Contributor), Li, J.-Y. (Contributor), Qin, X. (Contributor), Chen, Y.-C. (Contributor), Faver, J. C. (Contributor), Nyshadham, P. (Contributor), Sharma, K. L. (Contributor), Sankaran, B. (Contributor), Judge, A. (Contributor), Yu, Z. (Contributor), Li, F. (Contributor), Pollet, J. (Contributor), Harris, R. S. (Contributor), Matzuk, M. M. (Contributor), Palzkill, T. (Contributor) & Young, D. W. (Contributor), Protein Data Bank (PDB), Jul 26 2023
DOI: 10.2210/pdb7UR9/pdb, https://www.wwpdb.org/pdb?id=pdb_00007ur9
Dataset
Sars-Cov2 Main Protease in complex with CDD-1733
Jimmidi, R. (Contributor), Chamakuri, S. (Contributor), Lu, S. (Contributor), Ucisik, M. N. (Contributor), Chen, P.-J. (Contributor), Bohren, K. M. (Contributor), Moghadasi, S. A. (Contributor), Versteeg, L. (Contributor), Nnabuife, C. (Contributor), Li, J.-Y. (Contributor), Qin, X. (Contributor), Chen, Y.-C. (Contributor), Faver, J. C. (Contributor), Nyshadham, P. (Contributor), Sharma, K. L. (Contributor), Sankaran, B. (Contributor), Judge, A. (Contributor), Yu, Z. (Contributor), Li, F. (Contributor), Pollet, J. (Contributor), Harris, R. S. (Contributor), Matzuk, M. M. (Contributor), Palzkill, T. (Contributor) & Young, D. W. (Contributor), Protein Data Bank (PDB), Jul 26 2023
DOI: 10.2210/pdb7URB/pdb, https://www.wwpdb.org/pdb?id=pdb_00007urb
Dataset

Reuben Stewart Harris

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Collaborations and top research areas from the last five years

Dive into details

APOBEC3 mutagenesis drives therapy resistance in breast cancer

APOBEC affects tumor evolution and age at onset of lung cancer in smokers

A split luciferase system for studying coronavirus M^pro dimerization in vitro and in living cells

Azapeptide-Based SARS-CoV-2 Main Protease Inhibitors: Design, Synthesis, Enzyme Inhibition, Structural Determination, and Antiviral Activity

Differentiation signals induce APOBEC3A expression via GRHL3 in squamous epithelia and squamous cell carcinoma

Sars-Cov2 Main Protease in complex with CDD-1819

SARS-Cov2 Main protease in complex with inhibitor CDD-1845

Sars-Cov2 Main Protease in complex with CDD-1733

Reuben Stewart Harris

Fingerprint

Collaborations and top research areas from the last five years

Research output

Datasets