Peter J Houghton

  • 22705 Citations
  • 80 h-Index
1975 …2019
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Research Output 1975 2019

Relationship of DNA methylation to mutational changes and transcriptional organization in fusion-positive and fusion-negative rhabdomyosarcoma

Sun, W., Chatterjee, B., Shern, J. F., Patidar, R., Song, Y., Wang, Y., Walker, R. L., Pawel, B. R., Linardic, C. M., Houghton, P. J., Hewitt, S. M., Edelman, D. C., Khan, J., Meltzer, P. S. & Barr, F. G., Jan 1 2019, (Accepted/In press) In : International Journal of Cancer.

Research output: Contribution to journalArticle

DNA Methylation
1 Citations (Scopus)

Abemaciclib is active in preclinical models of Ewing sarcoma via multipronged regulation of cell cycle, DNA methylation, and interferon pathway signaling

Dowless, M., Lowery, C. D., Shackleford, T., Renschler, M., Stephens, J., Flack, R., Blosser, W., Gupta, S., Stewart, J., Webster, Y., Dempsey, J., VanWye, A. B., Ebert, P., Iversen, P., Olsen, J. B., Gong, X., Buchanan, S., Houghton, P. J. & Stancato, L., Dec 1 2018, In : Clinical Cancer Research. 24, 23, p. 6028-6039 12 p.

Research output: Contribution to journalArticle

Ewing's Sarcoma
DNA Methylation
Cell Cycle

Classical NF-κB metabolically reprograms sarcoma cells through regulation of hexokinase 2

Londhe, P., Yu, P. Y., Ijiri, Y., Ladner, K. J., Fenger, J. M., London, C., Houghton, P. J. & Guttridge, D. C., Apr 11 2018, In : Frontiers in Oncology. 8, APR, 104.

Research output: Contribution to journalArticle


ETV7 is an essential component of a rapamycin-insensitive mTOR complex in cancer

Harwood, F. C., Klein Geltink, R. I., O’Hara, B. P., Cardone, M., Janke, L., Finkelstein, D., Entin, I., Paul, L., Houghton, P. J. & Grosveld, G. C., Sep 12 2018, In : Science advances. 4, 9, eaar3938.

Research output: Contribution to journalArticle

Protein-Serine-Threonine Kinases
3 Citations (Scopus)

Initial testing (stage 1) of M6620 (formerly VX-970), a novel ATR inhibitor, alone and combined with cisplatin and melphalan, by the Pediatric Preclinical Testing Program

Kurmasheva, R. T., Kurmashev, D., Reynolds, C. P., Kang, M., Wu, J., Houghton, P. J. & Smith, M. A., Feb 1 2018, In : Pediatric Blood and Cancer. 65, 2, e26825.

Research output: Contribution to journalArticle

Disease-Free Survival