Peter J Houghton

  • 23445 Citations
  • 81 h-Index
1975 …2019
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Fingerprint Dive into the research topics where Peter J Houghton is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Heterografts Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
irinotecan Medicine & Life Sciences
Pediatrics Medicine & Life Sciences
Rhabdomyosarcoma Medicine & Life Sciences
Sirolimus Medicine & Life Sciences
Topotecan Medicine & Life Sciences
Tumors Chemical Compounds

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Research Output 1975 2019

2 Citations (Scopus)

A phase II study of alisertib in children with recurrent/refractory solid tumors or leukemia: Children's Oncology Group Phase I and pilot Consortium (ADVL0921)

Mosse, Y. P., Fox, E., Teachey, D. T., Reid, J. M., Safgren, S. L., Carol, H., Lock, R. B., Houghton, P. J., Smith, M. A., Hall, D., Barkauskas, D. A., Krailo, M., Voss, S. D., Berg, S. L., Blaney, S. M. & Weigel, B. J., Jun 1 2019, In : Clinical Cancer Research. 25, 11, p. 3229-3238 10 p.

Research output: Contribution to journalArticle

Open Access
Leukemia
Aurora Kinase A
Neoplasms
Pharmacokinetics
Pharmacogenetics
5 Citations (Scopus)

Broad spectrum activity of the checkpoint kinase 1 inhibitor prexasertib as a single agent or chemopotentiator across a range of preclinical pediatric tumor models

Lowery, C. D., Dowless, M., Renschler, M., Blosser, W., VanWye, A. B., Stephens, J. R., Iversen, P. W., Lin, A. B., Beckmann, R. P., Krytska, K., Cole, K. A., Maris, J. M., Hawkins, D. S., Rubin, B. P., Kurmasheva, R. T., Houghton, P. J., Gorlick, R., Anders Kolb, E., Kang, M. H., Patrick Reynolds, C. & 4 others, Erickson, S. W., Teicher, B. A., Smith, M. A. & Stancato, L. F., Apr 1 2019, In : Clinical Cancer Research. 25, 7, p. 2278-2289 12 p.

Research output: Contribution to journalArticle

Pediatrics
Neoplasms
Combination Drug Therapy
Heterografts
Sarcoma

Canine osteosarcoma genome sequencing identifies recurrent mutations in DMD and the histone methyltransferase gene SETD2

Gardner, H. L., Sivaprakasam, K., Briones, N., Zismann, V., Perdigones, N., Drenner, K., Facista, S., Richholt, R., Liang, W., Aldrich, J., Trent, J. M., Shields, P. G., Robinson, N., Johnson, J., Lana, S., Houghton, P. J., Fenger, J., Lorch, G., Janeway, K. A., London, C. A. & 1 others, Hendricks, W. P. D., Dec 1 2019, In : Communications Biology. 2, 1, 266.

Research output: Contribution to journalArticle

Open Access
osteosarcoma
methyltransferases
Osteosarcoma
histones
Canidae

Challenges and opportunities for childhood cancer drug development

Houghton, P. J. & Kurmasheva, R. T., Oct 1 2019, In : Pharmacological Reviews. 71, 4, p. 671-697 27 p.

Research output: Contribution to journalArticle

Pharmaceutical Preparations
Neoplasms
Therapeutics
Tumor Microenvironment
Cytotoxins
1 Citation (Scopus)

Emerging novel agents for patients with advanced Ewing sarcoma: a report from the Children’s Oncology Group (COG) new agents for ewing sarcoma task force [version 1; peer review: 3 approved]

Bailey, K., Cost, C., Davis, I., Glade-Bender, J., Grohar, P., Houghton, P. J., Isakoff, M., Stewart, E., Laack, N., Yustein, J., Reed, D., Janeway, K., Gorlick, R., Lessnick, S., DuBois, S. & Hingorani, P., Jan 1 2019, In : F1000Research. 8, 493.

Research output: Contribution to journalReview article

Open Access
Peer Review
Ewing's Sarcoma
Oncology
Proxy
Advisory Committees