Peter J Houghton

Mosse, Y. P., Fox, E., Teachey, D. T., Reid, J. M., Safgren, S. L., Carol, H., Lock, R. B., Houghton, P. J., Smith, M. A., Hall, D., Barkauskas, D. A., Krailo, M., Voss, S. D., Berg, S. L., Blaney, S. M. & Weigel, B. J., Jun 1 2019, In : Clinical Cancer Research. 25, 11, p. 3229-3238 10 p.

Research output: Contribution to journal › Article

Open Access

Leukemia

Aurora Kinase A

Neoplasms

Pharmacokinetics

Pharmacogenetics

5 Citations (Scopus)

Broad spectrum activity of the checkpoint kinase 1 inhibitor prexasertib as a single agent or chemopotentiator across a range of preclinical pediatric tumor models

Lowery, C. D., Dowless, M., Renschler, M., Blosser, W., VanWye, A. B., Stephens, J. R., Iversen, P. W., Lin, A. B., Beckmann, R. P., Krytska, K., Cole, K. A., Maris, J. M., Hawkins, D. S., Rubin, B. P., Kurmasheva, R. T., Houghton, P. J., Gorlick, R., Anders Kolb, E., Kang, M. H., Patrick Reynolds, C. & 4 others, Erickson, S. W., Teicher, B. A., Smith, M. A. & Stancato, L. F., Apr 1 2019, In : Clinical Cancer Research. 25, 7, p. 2278-2289 12 p.

Research output: Contribution to journal › Article

Pediatrics

Neoplasms

Combination Drug Therapy

Heterografts

Sarcoma

Canine osteosarcoma genome sequencing identifies recurrent mutations in DMD and the histone methyltransferase gene SETD2

Gardner, H. L., Sivaprakasam, K., Briones, N., Zismann, V., Perdigones, N., Drenner, K., Facista, S., Richholt, R., Liang, W., Aldrich, J., Trent, J. M., Shields, P. G., Robinson, N., Johnson, J., Lana, S., Houghton, P. J., Fenger, J., Lorch, G., Janeway, K. A., London, C. A. & 1 others, Hendricks, W. P. D., Dec 1 2019, In : Communications Biology. 2, 1, 266.

Research output: Contribution to journal › Article

Open Access

osteosarcoma

methyltransferases

Osteosarcoma

histones

Canidae

Challenges and opportunities for childhood cancer drug development

Houghton, P. J. & Kurmasheva, R. T., Oct 1 2019, In : Pharmacological Reviews. 71, 4, p. 671-697 27 p.

Research output: Contribution to journal › Article

Pharmaceutical Preparations

Neoplasms

Therapeutics

Tumor Microenvironment

Cytotoxins

1 Citation (Scopus)

Emerging novel agents for patients with advanced Ewing sarcoma: a report from the Children’s Oncology Group (COG) new agents for ewing sarcoma task force [version 1; peer review: 3 approved]

Bailey, K., Cost, C., Davis, I., Glade-Bender, J., Grohar, P., Houghton, P. J., Isakoff, M., Stewart, E., Laack, N., Yustein, J., Reed, D., Janeway, K., Gorlick, R., Lessnick, S., DuBois, S. & Hingorani, P., Jan 1 2019, In : F1000Research. 8, 493.

Research output: Contribution to journal › Review article

Open Access

Peer Review

Ewing's Sarcoma

Oncology

Proxy

Advisory Committees