Muralidharan Sargurupremraj

2024

A genome-wide association meta-analysis of all-cause and vascular dementia

The Mega Vascular Cognitive Impairment and Dementia (MEGAVCID) consortium, Sep 2024, In: Alzheimer's and Dementia. 20, 9, p. 5973-5995 23 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Basic Science and Pathogenesis

Sargurupremraj, M., Yang, Q., Jian, X., Himali, J. J. & Seshadri, S., Dec 1 2024, In: Alzheimer's and Dementia. 20, p. e085920

Research output: Contribution to journal › Article › peer-review

Open Access

Genetic Complexities of Cerebral Small Vessel Disease, Blood Pressure, and Dementia

Sargurupremraj, M., Soumaré, A., Bis, J. C., Surakka, I., Jürgenson, T., Joly, P., Knol, M. J., Wang, R., Yang, Q., Satizabal, C. L., Gudjonsson, A., Mishra, A., Bouteloup, V., Phuah, C. L., Van Duijn, C. M., Cruchaga, C., Dufouil, C., Chêne, G., Lopez, O. L. & Psaty, B. M. & 14 others, Tzourio, C., Amouyel, P., Adams, H. H., Jacqmin-Gadda, H., Ikram, M. A., Gudnason, V., Milani, L., Winsvold, B. S., Hveem, K., Matthews, P. M., Longstreth, W. T., Seshadri, S., Launer, L. J. & Debette, S., May 22 2024, In: JAMA network open. 7, 5, e2412824.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Genetic variants for head size share genes and pathways with cancer

The Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium & The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium, May 21 2024, In: Cell Reports Medicine. 5, 5, 101529.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries

García-Marín, L. M., Campos, A. I., Diaz-Torres, S., Rabinowitz, J. A., Ceja, Z., Mitchell, B. L., Grasby, K. L., Thorp, J. G., Agartz, I., Alhusaini, S., Ames, D., Amouyel, P., Andreassen, O. A., Arfanakis, K., Arias-Vasquez, A., Armstrong, N. J., Athanasiu, L., Bastin, M. E., Beiser, A. S. & Bennett, D. A. & 170 others, Bis, J. C., Boks, M. P. M., Boomsma, D. I., Brodaty, H., Brouwer, R. M., Buitelaar, J. K., Burkhardt, R., Cahn, W., Calhoun, V. D., Carmichael, O. T., Chakravarty, M., Chen, Q., Ching, C. R. K., Cichon, S., Crespo-Facorro, B., Crivello, F., Dale, A. M., Smith, G. D., de Geus, E. J. C., De Jager, P. L., de Zubicaray, G. I., Debette, S., DeCarli, C., Depondt, C., Desrivières, S., Djurovic, S., Ehrlich, S., Erk, S., Espeseth, T., Fernández, G., Filippi, I., Fisher, S. E., Fleischman, D. A., Fletcher, E., Fornage, M., Forstner, A. J., Francks, C., Franke, B., Ge, T., Goldman, A. L., Grabe, H. J., Green, R. C., Grimm, O., Groenewold, N. A., Gruber, O., Gudnason, V., Håberg, A. K., Haukvik, U. K., Heinz, A., Hibar, D. P., Hilal, S., Himali, J. J., Ho, B. C., Hoehn, D. F., Hoekstra, P. J., Hofer, E., Hoffmann, W., Holmes, A. J., Homuth, G., Hosten, N., Ikram, M. K., Ipser, J. C., Jack, C. R., Jahanshad, N., Jönsson, E. G., Kahn, R. S., Kanai, R., Klein, M., Knol, M. J., Launer, L. J., Lawrie, S. M., Hellard, S. L., Lee, P. H., Lemaître, H., Li, S., Liewald, D. C. M., Lin, H., Longstreth, W. T., Lopez, O. L., Luciano, M., Maillard, P., Marquand, A. F., Martin, N. G., Martinot, J. L., Mather, K. A., Mattay, V. S., McMahon, K. L., Mecocci, P., Melle, I., Meyer-Lindenberg, A., Mirza-Schreiber, N., Milaneschi, Y., Mosley, T. H., Mühleisen, T. W., Müller-Myhsok, B., Maniega, S. M., Nauck, M., Nho, K., Niessen, W. J., Nöthen, M. M., Nyquist, P. A., Oosterlaan, J., Pandolfo, M., Paus, T., Pausova, Z., Penninx, B. W. J. H., Pike, G. B., Psaty, B. M., Pütz, B., Reppermund, S., Rietschel, M. D., Risacher, S. L., Romanczuk-Seiferth, N., Romero-Garcia, R., Roshchupkin, G. V., Rotter, J. I., Sachdev, P. S., Sämann, P. G., Saremi, A., Sargurupremraj, M., Saykin, A. J., Schmaal, L., Schmidt, H., Schmidt, R., Schofield, P. R., Scholz, M., Schumann, G., Schwarz, E., Shen, L., Shin, J., Sisodiya, S. M., Smith, A. V., Smoller, J. W., Soininen, H. S., Steen, V. M., Stein, D. J., Stein, J. L., Thomopoulos, S. I., Toga, A. W., Tordesillas-Gutiérrez, D., Trollor, J. N., Valdes-Hernandez, M. C., van ′t Ent, D., van Bokhoven, H., van der Meer, D., van der Wee, N. J. A., Vázquez-Bourgon, J., Veltman, D. J., Vernooij, M. W., Villringer, A., Vinke, L. N., Völzke, H., Walter, H., Wardlaw, J. M., Weinberger, D. R., Weiner, M. W., Wen, W., Westlye, L. T., Westman, E., White, T., Witte, A. V., Wolf, C., Yang, J., Zwiers, M. P., Ikram, M. A., Seshadri, S., Thompson, P. M., Satizabal, C. L., Medland, S. E. & Rentería, M. E., Nov 2024, In: Nature Genetics. 56, 11, p. 2333-2344 12 p.

Research output: Contribution to journal › Article › peer-review

Multi-omics and pathway analyses of genome-wide associations implicate regulation and immunity in verbal declarative memory performance

Mei, H., Simino, J., Li, L., Jiang, F., Bis, J. C., Davies, G., Hill, W. D., Xia, C., Gudnason, V., Yang, Q., Lahti, J., Smith, J. A., Kirin, M., De Jager, P., Armstrong, N. J., Ghanbari, M., Kolcic, I., Moran, C., Teumer, A. & Sargurupremraj, M. & 47 others, Mahmud, S., Fornage, M., Zhao, W., Satizabal, C. L., Polasek, O., Räikkönen, K., Liewald, D. C., Homuth, G., Callisaya, M., Mather, K. A., Windham, B. G., Zemunik, T., Palotie, A., Pattie, A., van der Auwera, S., Thalamuthu, A., Knopman, D. S., Rudan, I., Starr, J. M., Wittfeld, K., Kochan, N. A., Griswold, M. E., Vitart, V., Brodaty, H., Gottesman, R., Cox, S. R., Psaty, B. M., Boerwinkle, E., Chasman, D. I., Grodstein, F., Sachdev, P. S., Srikanth, V., Hayward, C., Wilson, J. F., Eriksson, J. G., Kardia, S. L. R., Grabe, H. J., Bennett, D. A., Ikram, M. A., Deary, I. J., van Duijn, C. M., Launer, L., Fitzpatrick, A. L., Seshadri, S., Bressler, J., Debette, S. & Mosley, T. H., Dec 2024, In: Alzheimer's Research and Therapy. 16, 1, 14.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Prioritization of Kidney Cell Types Highlights Myofibroblast Cells in Regulating Human Blood Pressure

International Consortium of Blood Pressure, Jun 2024, In: Kidney International Reports. 9, 6, p. 1849-1859 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

The African Initiative for Bioinformatics Online Training in Neurodegenerative Diseases (AI-BOND): Investing in the next generation of African neuroscientists

Fongang, B., Ayele, B. A., Wadop, Y. N., Epenge, E., Nkouonlack, C. D., Njamnshi, W. Y., Jian, X., Sargurupremraj, M., Djotsa, A. B. S. N., Seke Etet, P. F., Bernal, R., Atangana, A., Cavazos, J. E., Himali, J. J., Fonteh, A. N., Maestre, G., Njamnshi, A. K. & Seshadri, S., Oct 1 2024, In: Alzheimer's and Dementia: Translational Research and Clinical Interventions. 10, 4, e70002.

Research output: Contribution to journal › Article › peer-review

Open Access

2023

Genetic Insights on the Relation of Vascular Risk Factors and Cervical Artery Dissection

CADISP Consortium, Oct 3 2023, In: Journal of the American College of Cardiology. 82, 14, p. 1411-1423 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Genetic Risk Score for Intracranial Aneurysms: Prediction of Subarachnoid Hemorrhage and Role in Clinical Heterogeneity

Bakker, M. K., Kanning, J. P., Abraham, G., Martinsen, A. E., Winsvold, B. S., Zwart, J. A., Bourcier, R., Sawada, T., Koido, M., Kamatani, Y., Morel, S., Amouyel, P., Debette, S., Bijlenga, P., Berrandou, T., Ganesh, S. K., Bouatia-Naji, N., Jones, G., Bown, M. & Rinkel, G. J. E. & 473 others, Veldink, J. H., Ruigrok, Y. M., Hege Aamodt, A., Heidi Skogholt, A., Brumpton, B. M., Willer, C. J., Sandset, E. C., Kristoffersen, E. S., Ellekjær, H., Heuch, I., Nielsen, J. B., Hagen, K., Hveem, K., Fritsche, L. G., Thomas, L. F., Pedersen, L. M., Gabrielsen, M. E., Holmen, O. L., Børte, S., Zhou, W., Abboud, S., Pandolfo, M., Thijs, V., Leys, D., Bodenant, M., Louillet, F., Touzé, E., Mas, J. L., Samson, Y., Leder, S., Léger, A., Deltour, S., Crozier, S., Méresse, I., Canaple, S., Godefroy, O., Giroud, M., Béjot, Y., Decavel, P., Medeiros, E., Montiel, P., Moulin, T., Vuillier, F., Dallongeville, J., Metso, A. J., Metso, T., Tatlisumak, T., Grond-Ginsbach, C., Lichy, C., Kloss, M., Werner, I., Arnold, M. L., Dos Santos, M., Grau, A., Dichgans, M., Thomas-Feles, C., Weber, R., Brandt, T., Pezzini, A., De Giuli, V., Caria, F., Poli, L., Padovani, A., Bersano, A., Lanfranconi, S., Beretta, S., Ferrarese, C., Giacolone, G., Paolucci, S., Lyrer, P., Engelter, S., Fluri, F., Hatz, F., Gisler, D., Bonati, L., Gensicke, H., Amort, M., Markus, H., Majersik, J., Worrall, B., Southerland, A., Cole, J., Kittner, S., Evangelou, E., Warren, H. R., Gao, H., Ntritsos, G., Dimou, N., Esko, T., Mägi, R., Milani, L., Almgren, P., Boutin, T., Ding, J., Giulianini, F., Holliday, E. G., Jackson, A. U., Li-Gao, R., Lin, W. Y., Luan, J., Mangino, M., Oldmeadow, C., Peter Prins, B., Qian, Y., Sargurupremraj, M., Shah, N., Surendran, P., Thériault, S., Verweij, N., Willems, S. M., Zhao, J. H., Connell, J., De Mutsert, R., Doney, A. S. F., Farrall, M., Menni, C., Morris, A. D., Noordam, R., Paré, G., Poulter, N. R., Shields, D. C., Stanton, A., Thom, S., Abecasis, G., Amin, N., Arking, D. E., Ayers, K. L., Barbieri, C. M., Batini, C., Bis, J. C., Blake, T., Bochud, M., Boehnke, M., Boerwinkle, E., Boomsma, D. I., Bottinger, E. P., Braund, P. S., Brumat, M., Campbell, A., Campbell, H., Chakravarti, A., Chambers, J. C., Chauhan, G., Ciullo, M., Cocca, M., Collins, F., Cordell, H. J., Davies, G., De Borst, M. H., De Geus, E. J., Deary, I. J., Deelen, J., Del Greco M, F., Yusuf Demirkale, C., Dörr, M., Ehret, G. B., Elosua, R., Enroth, S., Mesut Erzurumluoglu, A., Ferreira, T., Frånberg, M., Franco, O. H., Gandin, I., Gasparini, P., Giedraitis, V., Gieger, C., Girotto, G., Goel, A., Gow, A. J., Gudnason, V., Guo, X., Gyllensten, U., Hamsten, A., Harris, T. B., Harris, S. E., Hartman, C. A., Havulinna, A. S., Hicks, A. A., Hofer, E., Hofman, A., Hottenga, J. J., Huffman, J. E., Hwang, S. J., Ingelsson, E., James, A., Jansen, R., Jarvelin, M. R., Joehanes, R., Johansson, Å., Johnson, A. D., Joshi, P. K., Jousilahti, P., Wouter Jukema, J., Jula, A., Kähönen, M., Kathiresan, S., Keavney, B. D., Khaw, K. T., Knekt, P., Knight, J., Kolcic, I., Kooner, J. S., Koskinen, S., Kristiansson, K., Kutalik, Z., Laan, M., Larson, M., Launer, L. J., Lehne, B., Lehtimäki, T., Liewald, D. C. M., Lin, L., Lind, L., Lindgren, C. M., Liu, Y. M., Loos, R. J. F., Lopez, L. M., Lu, Y., Lyytikäinen, L. P., Mahajan, A., Mamasoula, C., Marrugat, J., Marten, J., Milaneschi, Y., Morgan, A., Morris, A. P., Morrison, A. C., Munson, P. J., Nalls, M. A., Nandakumar, P., Nelson, C. P., Niiranen, T., Nolte, I. M., Nutile, T., Oldehinkel, A. J., Oostra, B. A., O'reilly, P. F., Org, E., Padmanabhan, S., Palmas, W., Palotie, A., Pattie, A., Penninx, B. W. J. H., Perola, M., Peters, A., Polasek, O., Pramstaller, P. P., Tri Nguyen, Q., Raitakari, O. T., Rettig, R., Rice, K., Ridker, P. M., Ried, J. S., Riese, H., Ripatti, S., Robino, A., Rose, L. M., Rotter, J. I., Rudan, I., Ruggiero, D., Saba, Y., Sala, C. F., Salomaa, V., Samani, N. J., Sarin, A. P., Schmidt, R., Schmidt, H., Shrine, N., Siscovick, D., Smith, A. V., Snieder, H., Sõber, S., Sorice, R., Starr, J. M., Stott, D. J., Strachan, D. P., Strawbridge, R. J., Sundström, J., Swertz, M. A., Taylor, K. D., Teumer, A., Tobin, M. D., Tomaszewski, M., Toniolo, D., Traglia, M., Trompet, S., Tuomilehto, J., Tzourio, C., Uitterlinden, A. G., Vaez, A., Van Der Most, P. J., Van Duijn, C. M., Verwoert, G. C., Vitart, V., Völker, U., Vollenweider, P., Vuckovic, D., Watkins, H., Wild, S. H., Willemsen, G., Wilson, J. F., Wright, A. F., Yao, J., Zemunik, T., Zhang, W., Attia, J. R., Butterworth, A. S., Chasman, D. I., Conen, D., Cucca, F., Danesh, J., Hayward, C., Howson, J. M. M., Laakso, M., Lakatta, E. G., Langenberg, C., Melander, O., Mook-Kanamori, D. O., Palmer, C. N. A., Risch, L., Scott, R. A., Scott, R. J., Sever, P., Spector, T. D., Van Der Harst, P., Wareham, N. J., Zeggini, E., Levy, D., Munroe, P. B., Newton-Cheh, C., Brown, M. J., Metspalu, A., Psaty, B. M., Wain, L. V., Elliott, P., Caulfield, M. J., Gormley, P., Anttila, V., Palta, P., Esko, T., Pers, T. H., Farh, K. H., Cuenca-Leon, E., Muona, M., Furlotte, N. A., Kurth, T., Ingason, A., Mcmahon, G., Ligthart, L., Terwindt, G. M., Kallela, M., Freilinger, T. M., Ran, C., Gordon, S. G., Stam, A. H., Steinberg, S., Borck, G., Koiranen, M., Quaye, L., Adams, H. H. H., Lehtimäki, T., Sarin, A. P., Wedenoja, J., Hinds, D. A., Buring, J. E., Schürks, M., Ridker, P. M., Gudlaug Hrafnsdottir, M., Stefansson, H., Ring, S. M., Hottenga, J. J., Artto, V., Kaunisto, M., Vepsäläinen, S., Malik, R., Heath, A. C., Madden, P. A. F., Martin, N. G., Montgomery, G. W., Kurki, M. I., Kals, M., Mägi, R., Pärn, K., Hämäläinen, E., Huang, H., Byrnes, A. E., Franke, L., Huang, J., Stergiakouli, E., Lee, P. H., Sandor, C., Webber, C., Cader, Z., Muller-Myhsok, B., Schreiber, S., Meitinger, T., Eriksson, J. G., Salomaa, V., Heikkilä, K., Loehrer, E., Uitterlinden, A. G., Van Duijn, C. M., Cherkas, L., Pedersen, L. M., Stubhaug, A., Nielsen, C. S., Männikkö, M., Mihailov, E., Milani, L., Göbel, H., Esserlind, A. L., Francke Christensen, A., Folkmann Hansen, T., Werge, T., Kaprio, J., Aromaa, A. J., Raitakari, O., Arfan Ikram, M., Spector, T., Järvelin, M. R., Kubisch, C., Strachan, D. P., Ferrari, M. D., Belin, A. C., Wessman, M., Van Den Maagdenberg, A. M. J. M., Davey Smith, G., Stefansson, K., Eriksson, N., Daly, M. J., Neale, B. M., Olesen, J., Chasman, D. I., Nyholt, D. R., Akiyama, M., Alg, V. S., Børte, S., Broderick, J. P., Dauvillier, J., Desal, H., Dina, C., Friedrich, C. M., Gaál-Paavola, E. I., Gentric, J. C., Hirsch, S., Hostettler, I. C., Houlden, H., Hveem, K., Jääskeläinen, J. E., Johnsen, M. B., Li, L., Lin, K., Lindgren, A., Martin, O., Matsuda, K., Millwood, I. Y., Naggara, O., Niemelä, M., Pera, J., Redon, R., Rouleau, G. A., Sandvei, M. S., Schilling, S., Shotar, E., Slowik, A., Terao, C., Verschuren, W. M. M., Walters, R. G., Werring, D. J., Willer, C. J., Woo, D., Worrall, B. B. & Zhou, S., Mar 1 2023, In: Stroke. 54, 3, p. 810-818 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Genomics of perivascular space burden unravels early mechanisms of cerebral small vessel disease

CHARGE Consortium, Apr 2023, In: Nature Medicine. 29, 4, p. 950-962 13 p.

Research output: Contribution to journal › Article › peer-review

43 Scopus citations

Obesity impacts the expression of Alzheimer's disease–related genes: The Framingham Heart Study

Charisis, S., Lin, H., Ray, R., Joehanes, R., Beiser, A. S., Levy, D., Seshadri, S., Sargurupremraj, M. & Satizabal, C. L., Aug 2023, In: Alzheimer's and Dementia. 19, 8, p. 3496-3505 10 p.

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

2022

Associations Between Brainstem Volume and Alzheimer's Disease Pathology in Middle-Aged Individuals of the Framingham Heart Study

Jacobs, H. I. L., O'donnell, A., Satizabal, C. L., Lois, C., Kojis, D., Hanseeuw, B. J., Thibault, E., Sanchez, J. S., Buckley, R. F., Yang, Q., Decarli, C., Killiany, R., Sargurupremraj, M., Sperling, R. A., Johnson, K. A., Beiser, A. S. & Seshadri, S., 2022, In: Journal of Alzheimer's Disease. 86, 4, p. 1603-1609 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Circulating Metabolome and White Matter Hyperintensities in Women and Men

Sliz, E., Shin, J., Ahmad, S., Williams, D. M., Frenzel, S., Gauß, F., Harris, S. E., Henning, A. K., Hernandez, M. V., Hu, Y. H., Jiménez, B., Sargurupremraj, M., Sudre, C., Wang, R., Wittfeld, K., Yang, Q., Wardlaw, J. M., Völzke, H., Vernooij, M. W. & Schott, J. M. & 19 others, Richards, M., Proitsi, P., Nauck, M., Lewis, M. R., Launer, L., Hosten, N., Grabe, H. J., Ghanbari, M., Deary, I. J., Cox, S. R., Chaturvedi, N., Barnes, J., Rotter, J. I., Debette, S., Ikram, M. A., Fornage, M., Paus, T., Seshadri, S. & Pausova, Z., Apr 5 2022, In: Circulation. 145, 14, p. 1040-1052 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Scopus citations

Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate

Mishra, A., Duplaà, C., Vojinovic, D., Suzuki, H., Sargurupremraj, M., Zilhão, N. R., Li, S., Bartz, T. M., Jian, X., Zhao, W., Hofer, E., Wittfeld, K., Harris, S. E., Van Der Auwera-Palitschka, S., Luciano, M., Bis, J. C., Adams, H. H. H., Satizabal, C. L., Gottesman, R. F. & Gampawar, P. G. & 47 others, Bülow, R., Weiss, S., Yu, M., Bastin, M. E., Lopez, O. L., Vernooij, M. W., Beiser, A. S., Völker, U., Kacprowski, T., Soumare, A., Smith, J. A., Knopman, D. S., Morris, Z., Zhu, Y., Rotter, J. I., Dufouil, C., Valdes Hernández, M., Muñoz Maniega, S., Lathrop, M., Boerwinkle, E., Schmidt, R., Ihara, M., Mazoyer, B., Yang, Q., Joutel, A., Tournier-Lasserve, E., Launer, L. J., Deary, I. J., Mosley, T. H., Amouyel, P., Decarli, C. S., Psaty, B. M., Tzourio, C., Kardia, S. L. R., Grabe, H. J., Teumer, A., Van Duijn, C. M., Schmidt, H., Wardlaw, J. M., Ikram, M. A., Fornage, M., Gudnason, V., Seshadri, S., Matthews, P. M., Longstreth, W. T., Couffinhal, T. & Debette, S., Jun 1 2022, In: Brain. 145, 6, p. 1992-2007 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

Genome-wide associations of aortic distensibility suggest causality for aortic aneurysms and brain white matter hyperintensities

Francis, C. M., Futschik, M. E., Huang, J., Bai, W., Sargurupremraj, M., Teumer, A., Breteler, M. M. B., Petretto, E., Ho, A. S. R., Amouyel, P., Engelter, S. T., Bülow, R., Völker, U., Völzke, H., Dörr, M., Imtiaz, M. A., Aziz, N. A., Lohner, V., Ware, J. S. & Debette, S. & 3 others, Elliott, P., Dehghan, A. & Matthews, P. M., Dec 2022, In: Nature communications. 13, 1, 4505.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Scopus citations

Genomic Studies Across the Lifespan Point to Early Mechanisms Determining Subcortical Volumes

Le Grand, Q., Satizabal, C. L., Sargurupremraj, M., Mishra, A., Soumaré, A., Laurent, A., Crivello, F., Tsuchida, A., Shin, J., Macalli, M., Singh, B., Beiser, A. S., DeCarli, C., Fletcher, E., Paus, T., Lathrop, M., Adams, H. H. H., Bis, J. C., Seshadri, S. & Tzourio, C. & 2 others, Mazoyer, B. & Debette, S., Jun 2022, In: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 7, 6, p. 616-628 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Migraine, Stroke, and Cervical Arterial Dissection: Shared Genetics for a Triad of Brain Disorders with Vascular Involvement

Daghals, I., Sargurupremraj, M., Danning, R., Gormley, P., Malik, R., Amouyel, P., Metso, T., Pezzini, A., Kurth, T., Debette, S. & Chasman, D., Feb 1 2022, In: Neurology: Genetics. 8, 1, e653.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Scopus citations

Multi-phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations

Temprano-Sagrera, G., Sitlani, C. M., Bone, W. P., Martin-Bornez, M., Voight, B. F., Morrison, A. C., Damrauer, S. M., de Vries, P. S., Smith, N. L., Sabater-Lleal, M., Dehghan, A., Heath, A. S., Morrison, A. C., Reiner, A. P., Johnson, A., Richmond, A., Peters, A., van Hylckama Vlieg, A., McKnight, B. & Psaty, B. M. & 363 others, Hayward, C., Ward-Caviness, C., O’Donnell, C., Chasman, D., Strachan, D. P., Tregouet, D. A., Mook-Kanamori, D., Gill, D., Thibord, F., Asselbergs, F. W., Leebeek, F. W. G., Rosendaal, F. R., Davies, G., Homuth, G., Temprano, G., Campbell, H., Taylor, H. A., Bressler, J., Huffman, J. E., Rotter, J. I., Yao, J., Wilson, J. F., Bis, J. C., Hahn, J. M., Desch, K. C., Wiggins, K. L., Raffield, L. M., Bielak, L. F., Yanek, L. R., Kleber, M. E., Mueller, M., Kavousi, M., Mangino, M., Liu, M., Brown, M. R., Conomos, M. P., Jhun, M. A., Chen, M. H., de Maat, M. P. M., Pankratz, N., Smith, N. L., Peyser, P. A., Elliot, P., Wei, P., Wild, P. S., Morange, P. E., van der Harst, P., Yang, Q., Le, N. Q., Marioni, R., Li, R., Damrauer, S. M., Cox, S. R., Trompet, S., Felix, S. B., Völker, U., Tang, W., Koenig, W., Jukema, J. W., Guo, X., Lindstrom, S., Wang, L., Smith, E. N., Gordon, W., van Hylckama Vlieg, A., de Andrade, M., Brody, J. A., Pattee, J. W., Haessler, J., Brumpton, B. M., Suchon, P., Chen, M. H., Turman, C., Germain, M., Wiggins, K. L., MacDonald, J., Braekkan, S. K., Armasu, S. M., Pankratz, N., Jackson, R. D., Nielsen, J. B., Giulianini, F., Puurunen, M. K., Ibrahim, M., Heckbert, S. R., Bammler, T. K., Frazer, K. A., McCauley, B. M., Taylor, K., Pankow, J. S., Reiner, A. P., Gabrielsen, M. E., Deleuze, J. F., O’Donnell, C. J., Kim, J., McKnight, B., Kraft, P., Hansen, J. B., Rosendaal, F. R., Heit, J. A., Psaty, B. M., Tang, W., Kooperberg, C., Hveem, K., Ridker, P. M., Morange, P. E., Johnson, A. D., Kabrhel, C., Trégouët, D. A., Smith, N. L., Malik, R., Chauhan, G., Traylor, M., Sargurupremraj, M., Okada, Y., Mishra, A., Rutten-Jacobs, L., Giese, A. K., van der Laan, S. W., Gretarsdottir, S., Anderson, C. D., Chong, M., Adams, H. H. H., Ago, T., Almgren, P., Amouyel, P., Ay, H., Bartz, T. M., Benavente, O. R., Bevan, S., Boncoraglio, G. B., Brown, R. D., Butterworth, A. S., Carrera, C., Carty, C. L., Chen, W. M., Cole, J. W., Correa, A., Cotlarciuc, I., Cruchaga, C., Danesh, J., de Bakker, P. I. W., DeStefano, A. L., den Hoed, M., Duan, Q., Engelter, S. T., Falcone, G. J., Gottesman, R. F., Grewal, R. P., Gudnason, V., Gustafsson, S., Haessler, J., Harris, T. B., Hassan, A., Havulinna, A. S., Heckbert, S. R., Holliday, E. G., Howard, G., Hsu, F. C., Hyacinth, H. I., Arfan Ikram, M., Ingelsson, E., Irvin, M. R., Jian, X., Jiménez-Conde, J., Johnson, J. A., Jukema, J. W., Kanai, M., Keene, K. L., Kissela, B. M., Kleindorfer, D. O., Kooperberg, C., Kubo, M., Lange, L. A., Langefeld, C. D., Langenberg, C., Launer, L. J., Lee, J. M., Lemmens, R., Leys, D., Lewis, C. M., Lin, W. Y., Lindgren, A. G., Lorentzen, E., Magnusson, P. K., Maguire, J., Manichaikul, A., McArdle, P. F., Meschia, J. F., Mitchell, B. D., Mosley, T. H., Nalls, M. A., Ninomiya, T., O’Donnell, M. J., Psaty, B. M., Pulit, S. L., Rannikmäe, K., Reiner, A. P., Rexrode, K. M., Rice, K., Rich, S. S., Ridker, P. M., Rost, N. S., Rothwell, P. M., Rotter, J. I., Rundek, T., Sacco, R. L., Sakaue, S., Sale, M. M., Salomaa, V., Sapkota, B. R., Schmidt, R., Schmidt, C. O., Schminke, U., Sharma, P., Slowik, A., Sudlow, C. L. M., Tanislav, C., Tatlisumak, T., Taylor, K. D., Thijs, V. N. S., Thorleifsson, G., Thorsteinsdottir, U., Tiedt, S., Trompet, S., Tzourio, C., van Duijn, C. M., Walters, M., Wareham, N. J., Wassertheil-Smoller, S., Wilson, J. G., Wiggins, K. L., Yang, Q., Yusuf, S., Amin, N., Aparicio, H. S., Arnett, D. K., Attia, J., Beiser, A. S., Berr, C., Buring, J. E., Bustamante, M., Caso, V., Cheng, Y. C., Hoan Choi, S., Chowhan, A., Cullell, N., Dartigues, J. F., Delavaran, H., Delgado, P., Dörr, M., Engström, G., Ford, I., Gurpreet, W. S., Hamsten, A., Heitsch, L., Hozawa, A., Ibanez, L., Ilinca, A., Ingelsson, M., Iwasaki, M., Jackson, R. D., Jood, K., Jousilahti, P., Kaffashian, S., Kalra, L., Kamouchi, M., Kitazono, T., Kjartansson, O., Kloss, M., Koudstaal, P. J., Krupinski, J., Labovitz, D. L., Laurie, C. C., Levi, C. R., Li, L., Lind, L., Lindgren, C. M., Lioutas, V., Mei Liu, Y., Lopez, O. L., Makoto, H., Martinez-Majander, N., Matsuda, K., Minegishi, N., Montaner, J., Morris, A. P., Muiño, E., Müller-Nurasyid, M., Norrving, B., Ogishima, S., Parati, E. A., Reddy Peddareddygari, L., Pedersen, N. L., Pera, J., Perola, M., Pezzini, A., Pileggi, S., Rabionet, R., Riba-Llena, I., Ribasés, M., Romero, J. R., Roquer, J., Rudd, A. G., Sarin, A. P., Sarju, R., Sarnowski, C., Sasaki, M., Satizabal, C. L., Satoh, M., Sattar, N., Sawada, N., Sibolt, G., Sigurdsson, Á., Smith, A., Sobue, K., Soriano-Tárraga, C., Stanne, T., Colin Stine, O., Stott, D. J., Strauch, K., Takai, T., Tanaka, H., Tanno, K., Teumer, A., Tomppo, L., Torres-Aguila, N. P., Touze, E., Tsugane, S., Uitterlinden, A. G., Valdimarsson, E. M., van der Lee, S. J., Völzke, H., Wakai, K., Weir, D., Williams, S. R., Wolfe, C. D. A., Wong, Q., Xu, H., Yamaji, T., Sanghera, D. K., Melander, O., Jern, C., Strbian, D., Fernandez-Cadenas, I., Longstreth, W. T., Rolfs, A., Hata, J., Woo, D., Rosand, J., Pare, G., Hopewell, J. C., Saleheen, D., Stefansson, K., Worrall, B. B., Kittner, S. J., Seshadri, S., Fornage, M., Markus, H. S., Howson, J. M. M., Kamatani, Y., Debette, S. & Dichgans, M., Jun 1 2022, In: Journal of Thrombosis and Haemostasis. 20, 6, p. 1331-1349 19 p.

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13 Scopus citations

New insights into the genetic etiology of Alzheimer’s disease and related dementias

EADB, GR@ACE, DEGESCO, EADI, GERAD, Demgene, FinnGen, ADGC & CHARGE, Apr 1 2022, In: Nature Genetics. 54, 4, p. 412-436 25 p.

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Open Access

923 Scopus citations

Stroke-associated intergenic variants modulate a human FOXF2 transcriptional enhancer

Ryu, J. R., Ahuja, S., Arnold, C. R., Potts, K. G., Mishra, A., Yang, Q., Sargurupremraj, M., Mahoney, D. J., Seshadri, S., Debette, S. & Childs, S. J., Aug 30 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 35, e2121333119.

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Open Access

3 Scopus citations

Stroke genetics informs drug discovery and risk prediction across ancestries

The COMPASS Consortium, The INVENT Consortium, The Dutch Parelsnoer Initiative (PSI) Cerebrovascular Disease Study Group, The Estonian Biobank, The PRECISEQ Consortium, The FinnGen Consortium, The NINDS Stroke Genetics Network (SiGN), The MEGASTROKE Consortium, The SIREN Consortium, The China Kadoorie Biobank Collaborative Group, the VA Million Veteran Program, The International Stroke Genetics Consortium (ISGC), The Biobank Japan, The CHARGE Consortium, The GIGASTROKE Consortium, Regeneron Genetics Center, The ODYSSEY Study, HUNT All-In Stroke, The SICFAIL Study & The Generacion Study & 6 others, The Copenhagen City Heart Study, The SMART Study, Clinical Research Collaboration for Stroke in Korea (CRCS-K) and Korea Biobank Array (KBA) Project, Helsinki Stroke Project, Follow-up Studies & EPIC-CVD, Nov 3 2022, In: Nature. 611, 7934, p. 115-123 9 p.

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Open Access

207 Scopus citations

2020

Cerebral small vessel disease genomics and its implications across the lifespan

International Headache Genomics Consortium (IHGC) & International Network against Thrombosis (INVENT) Consortium, Dec 2020, In: Nature communications. 11, 1, 6285.

Research output: Contribution to journal › Article › peer-review

Open Access

113 Scopus citations

Common genetic variation indicates separate causes for periventricular and deep white matter hyperintensities

Armstrong, N. J., Mather, K. A., Sargurupremraj, M., Knol, M. J., Malik, R., Satizabal, C. L., Yanek, L. R., Wen, W., Gudnason, V. G., Dueker, N. D., Elliott, L. T., Hofer, E., Bis, J., Jahanshad, N., Li, S., Logue, M. A., Luciano, M., Scholz, M., Smith, A. V. & Trompet, S. & 66 others, Vojinovic, D., Xia, R., Alfaro-Almagro, F., Ames, D., Amin, N., Amouyel, P., Beiser, A. S., Brodaty, H., Deary, I. J., Fennema-Notestine, C., Gampawar, P. G., Gottesman, R., Griffanti, L., Jack, C. R., Jenkinson, M., Jiang, J., Kral, B. G., Kwok, J. B., Lampe, L., Liewald, D. C. M., Maillard, P., Marchini, J., Bastin, M. E., Mazoyer, B., Pirpamer, L., Romero, J. R., Roshchupkin, G. V., Schofield, P. R., Schroeter, M. L., Stott, D. J., Thalamuthu, A., Trollor, J., Tzourio, C., van der Grond, J., Vernooij, M. W., Witte, V. A., Wright, M. J., Yang, Q., Morris, Z., Siggurdsson, S., Psaty, B., Villringer, A., Schmidt, H., Haberg, A. K., van Duijn, C. M., Wouter Jukema, J., Dichgans, M., Sacco, R. L., Wright, C. B., Kremen, W. S., Becker, L. C., Thompson, P. M., Mosley, T. H., Wardlaw, J. M., Ikram, M. A., Adams, H. H. H., Seshadri, S., Sachdev, P. S., Smith, S. M., Launer, L., Longstreth, W., DeCarli, C., Schmidt, R., Fornage, M., Debette, S. & Nyquist, P. A., Jul 2020, In: Stroke. 51, 7, p. 2112-2121 10 p.

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69 Scopus citations

Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors

HUNT All-In Stroke, China Kadoorie Biobank Collaborative Group, BioBank Japan Project Consortium, The ICAN Study Group, CADISP Group, Genetics and Observational Subarachnoid Haemorrhage (GOSH) Study investigators & International Stroke Genetics Consortium (ISGC), Dec 2020, In: Nature Genetics. 52, 12, p. 1303-1313 11 p.

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Open Access

187 Scopus citations

2019

A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology

INVENT Consortium, MEGASTROKE Consortium of the International Stroke Genetics Consortium, 2019, In: Blood. 133, 9, p. 967-977 11 p.

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Open Access

32 Scopus citations

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting

Stroke Genetics Network (SiGN), International Stroke Genetics Consortium (ISGC), METASTROKE, Alzheimer’s Disease Genetics Consortium (ADGC) & Neurology Working Group of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, Jan 29 2019, In: Neurology. 92, 5, p. E486-E503

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Open Access

32 Scopus citations

Genetic architecture of subcortical brain structures in 38,851 individuals

Satizabal, C. L., Adams, H. H. H., Hibar, D. P., White, C. C., Knol, M. J., Stein, J. L., Scholz, M., Sargurupremraj, M., Jahanshad, N., Roshchupkin, G. V., Smith, A. V., Bis, J. C., Jian, X., Luciano, M., Hofer, E., Teumer, A., van der Lee, S. J., Yang, J., Yanek, L. R. & Lee, T. V. & 269 others, Li, S., Hu, Y., Koh, J. Y., Eicher, J. D., Desrivières, S., Arias-Vasquez, A., Chauhan, G., Athanasiu, L., Rentería, M. E., Kim, S., Hoehn, D., Armstrong, N. J., Chen, Q., Holmes, A. J., den Braber, A., Kloszewska, I., Andersson, M., Espeseth, T., Grimm, O., Abramovic, L., Alhusaini, S., Milaneschi, Y., Papmeyer, M., Axelsson, T., Ehrlich, S., Roiz-Santiañez, R., Kraemer, B., Håberg, A. K., Jones, H. J., Pike, G. B., Stein, D. J., Stevens, A., Bralten, J., Vernooij, M. W., Harris, T. B., Filippi, I., Witte, A. V., Guadalupe, T., Wittfeld, K., Mosley, T. H., Becker, J. T., Doan, N. T., Hagenaars, S. P., Saba, Y., Cuellar-Partida, G., Amin, N., Hilal, S., Nho, K., Mirza-Schreiber, N., Arfanakis, K., Becker, D. M., Ames, D., Goldman, A. L., Lee, P. H., Boomsma, D. I., Lovestone, S., Giddaluru, S., Le Hellard, S., Mattheisen, M., Bohlken, M. M., Kasperaviciute, D., Schmaal, L., Lawrie, S. M., Agartz, I., Walton, E., Tordesillas-Gutierrez, D., Davies, G. E., Shin, J., Ipser, J. C., Vinke, L. N., Hoogman, M., Jia, T., Burkhardt, R., Klein, M., Crivello, F., Janowitz, D., Carmichael, O., Haukvik, U. K., Aribisala, B. S., Schmidt, H., Strike, L. T., Cheng, C. Y., Risacher, S. L., Pütz, B., Fleischman, D. A., Assareh, A. A., Mattay, V. S., Buckner, R. L., Mecocci, P., Dale, A. M., Cichon, S., Boks, M. P., Matarin, M., Penninx, B. W. J. H., Calhoun, V. D., Chakravarty, M. M., Marquand, A. F., Macare, C., Kharabian Masouleh, S., Oosterlaan, J., Amouyel, P., Hegenscheid, K., Rotter, J. I., Schork, A. J., Liewald, D. C. M., de Zubicaray, G. I., Wong, T. Y., Shen, L., Sämann, P. G., Brodaty, H., Roffman, J. L., de Geus, E. J. C., Tsolaki, M., Erk, S., van Eijk, K. R., Cavalleri, G. L., van der Wee, N. J. A., McIntosh, A. M., Gollub, R. L., Bulayeva, K. B., Bernard, M., Richards, J. S., Himali, J. J., Loeffler, M., Rommelse, N., Hoffmann, W., Westlye, L. T., Valdés Hernández, M. C., Hansell, N. K., van Erp, T. G. M., Wolf, C., Kwok, J. B. J., Vellas, B., Heinz, A., Olde Loohuis, L. M., Delanty, N., Ho, B. C., Ching, C. R. K., Shumskaya, E., Singh, B., Hofman, A., van der Meer, D., Homuth, G., Psaty, B. M., Bastin, M. E., Montgomery, G. W., Foroud, T. M., Reppermund, S., Hottenga, J. J., Simmons, A., Meyer-Lindenberg, A., Cahn, W., Whelan, C. D., van Donkelaar, M. M. J., Yang, Q., Hosten, N., Green, R. C., Thalamuthu, A., Mohnke, S., Hulshoff Pol, H. E., Lin, H., Jack, C. R., Schofield, P. R., Mühleisen, T. W., Maillard, P., Potkin, S. G., Wen, W., Fletcher, E., Toga, A. W., Gruber, O., Huentelman, M., Davey Smith, G., Launer, L. J., Nyberg, L., Jönsson, E. G., Crespo-Facorro, B., Koen, N., Greve, D. N., Uitterlinden, A. G., Weinberger, D. R., Steen, V. M., Fedko, I. O., Groenewold, N. A., Niessen, W. J., Toro, R., Tzourio, C., Longstreth, W. T., Ikram, M. K., Smoller, J. W., van Tol, M. J., Sussmann, J. E., Paus, T., Lemaître, H., Schroeter, M. L., Mazoyer, B., Andreassen, O. A., Holsboer, F., Depondt, C., Veltman, D. J., Turner, J. A., Pausova, Z., Schumann, G., van Rooij, D., Djurovic, S., Deary, I. J., McMahon, K. L., Müller-Myhsok, B., Brouwer, R. M., Soininen, H., Pandolfo, M., Wassink, T. H., Cheung, J. W., Wolfers, T., Martinot, J. L., Zwiers, M. P., Nauck, M., Melle, I., Martin, N. G., Kanai, R., Westman, E., Kahn, R. S., Sisodiya, S. M., White, T., Saremi, A., van Bokhoven, H., Brunner, H. G., Völzke, H., Wright, M. J., van ‘t Ent, D., Nöthen, M. M., Ophoff, R. A., Buitelaar, J. K., Fernández, G., Sachdev, P. S., Rietschel, M., van Haren, N. E. M., Fisher, S. E., Beiser, A. S., Francks, C., Saykin, A. J., Mather, K. A., Romanczuk-Seiferth, N., Hartman, C. A., DeStefano, A. L., Heslenfeld, D. J., Weiner, M. W., Walter, H., Hoekstra, P. J., Nyquist, P. A., Franke, B., Bennett, D. A., Grabe, H. J., Johnson, A. D., Chen, C., van Duijn, C. M., Lopez, O. L., Fornage, M., Wardlaw, J. M., Schmidt, R., DeCarli, C., De Jager, P. L., Villringer, A., Debette, S., Gudnason, V., Medland, S. E., Shulman, J. M., Thompson, P. M., Seshadri, S. & Ikram, M. A., Nov 1 2019, In: Nature Genetics. 51, 11, p. 1624-1636 13 p.

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172 Scopus citations

Genome-wide association study of cerebral small vessel disease reveals established and novel loci

International Stroke Genetics Consortium, Oct 1 2019, In: Brain. 142, 10, p. 3176-3189 14 p.

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79 Scopus citations

Serum magnesium and calcium levels in relation to ischemic stroke: Mendelian randomization study

Larsson, S. C., Traylor, M., Burgess, S., Boncoraglio, G. B., Jern, C., Michaëlsson, K., Markus, H. S., Malik, R., Chauhan, G., Sargurupremraj, M., Okada, Y., Mishra, A., Rutten-Jacobs, L., Giese, A. K., Van Der Laan, S. W., Gretarsdottir, S., Anderson, C. D., Chong, M., Adams, H. H. H. & Ago, T. & 237 others, Almgren, P., Amouyel, P., Ay, H., Bartz, R. M., Benavente, O. R., Bevan, S., Brown, R. D., Butterworth, A. S., Carrera, C., Carty, C. L., Chasman, D. I., Chen, W. M., Cole, J. W., Correa, A., Cotlarciuc, I., Cruchaga, C., Danesh, J., De Bakker, P. I. W., Destefano, A. L., Hoed, M. D., Duan, Q., Engelter, S. T., Falcone, G. J., Gottesman, R. F., Grewal, R. P., Gudnason, V., Gustafsson, S., Haessler, J., Harris, T. B., Hassan, A., Havulinna, A. S., Heckbert, S. R., Holliday, E. G., Howard, G., Hsu, F. C., Hyacinth, H. I., Ikram, M. A., Ingelsson, E., Irvin, M. R., Jian, X., Jiménez-Conde, J., Johnson, J. A., Jukema, J. W., Kanai, M., Keene, K. L., Kissela, B. M., Kleindorfer, D. O., Kooperberg, C., Kubo, M., Lange, L. A., Langefeld, C. D., Langenberg, C., Launer, L. J., Lee, J. M., Lemmens, R., Leys, D., Lewis, C. M., Lin, W. Y., Lindgren, A. G., Lorentzen, E., Magnusson, P. K., Maguire, J., Manichaikul, A., McArdle, P. F., Meschia, J. F., Mitchell, B. D., Mosley, T. H., Nalls, M. A., Ninomiya, T., O'Donnell, M. J., Psaty, B. M., Pulit, S. L., Rannikmäe, K., Reiner, A. P., Rexrode, K. M., Rice, K., Rich, S. S., Ridker, P. M., Rost, N. S., Rothwell, P. M., Rotter, J. I., Rundek, T., Sacco, R. L., Sakaue, S., Sale, M. M., Salomaa, V., Sapkota, B. R., Schmidt, R., Schmidt, C. O., Schminke, U., Sharma, P., Slowik, A., Sudlow, C. L. M., Tanislav, C., Tatlisumak, T., Taylor, K. D., Thijs, V. N. S., Thorleifsson, G., Thorsteinsdottir, U., Tiedt, S., Trompet, S., Tzourio, C., Van Duijn, C. M., Walters, M., Wareham, N. J., Wassertheil-Smoller, S., Wilson, J. G., Wiggins, K. L., Yang, Q., Yusuf, S., Amin, N., Aparicio, H. S., Arnett, D. K., Attia, J., Beiser, A. S., Berr, C., Buring, J. E., Bustamante, M., Caso, V., Cheng, Y. C., Choi, S. H., Chowhan, A., Cullell, N., Dartigues, J. F., Delavaran, H., Delgado, P., Dörr, M., Engström, G., Ford, I., Gurpreet, W. S., Hamsten, A., Heitsch, L., Hozawa, A., Ibanez, L., Ilinca, A., Ingelsson, M., Iwasaki, M., Jackson, R. D., Jood, K., Jousilahti, P., Kaffashian, S., Kalra, L., Kamouchi, M., Kitazono, T., Kjartansson, O., Kloss, M., Koudstaal, P. J., Krupinski, J., Labovitz, D. L., Laurie, C. C., Levi, C. R., Li, L., Lind, L., Lindgren, C. M., Lioutas, V., Liu, Y. M., Lopez, O. L., Makoto, H., Martinez-Majander, N., Matsuda, K., Minegishi, N., Montaner, J., Morris, A. P., Muiño, E., Müller-Nurasyid, M., Norrving, B., Ogishima, S., Parati, E. A., Peddareddygari, L. R., Pedersen, N. L., Pera, J., Perola, M., Pezzini, A., Pileggi, S., Rabionet, R., Riba-Llena, I., Ribasés, M., Romero, J. R., Roquer, J., Rudd, A. G., Sarin, A. P., Sarju, R., Sarnowski, C., Sasaki, M., Satizabal, C. L., Satoh, M., Sattar, N., Sawada, N., Sibolt, G., Sigurdsson, Á., Smith, A., Sobue, K., Soriano-Tárraga, C., Stanne, T., Stine, O. C., Stott, D. J., Strauch, K., Takai, T., Tanaka, H., Tanno, K., Teumer, A., Tomppo, L., Torres-Aguila, N. P., Touze, E., Tsugane, S., Uitterlinden, A. G., Valdimarsson, E. M., Van Der Lee, S. J., Völzke, H., Wakai, K., Weir, D., Williams, S. R., Wolfe, C. D. A., Wong, Q., Xu, H., Yamaji, T., Sanghera, D. K., Melander, O., Strbian, D., Fernandez-Cadenas, I., Longstreth, W. T., Rolfs, A., Hata, J., Woo, D., Rosand, J., Pare, G., Hopewell, J. C., Saleheen, D., Stefansson, K., Worrall, B. B., Kittner, S. J., Seshadri, S., Fornage, M., Howson, J. M. M., Kamatani, Y., Debette, S. & Dichgans, M., Feb 26 2019, In: Neurology. 92, 9, p. E944-E950

Research output: Contribution to journal › Article › peer-review

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47 Scopus citations

Trans-ethnic association study of blood pressure determinants in over 750,000 individuals

Understanding Society Scientific Group, International Consortium for Blood Pressure, Blood Pressure-International Consortium of Exome Chip Studies & Million Veteran Program, Jan 1 2019, In: Nature Genetics. 51, 1, p. 51-62 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

291 Scopus citations

2018

Burden of dilated perivascular spaces, an emerging marker of cerebral small vessel disease, is highly heritable

Duperron, M. G., Tzourio, C., Sargurupremraj, M., Mazoyer, B., Soumaré, A., Schilling, S., Amouyel, P., Chauhan, G., Zhu, Y. C. & Debette, S., 2018, In: Stroke. 49, 2, p. 282-287 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

68 Scopus citations

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

the Million Veteran Program, Oct 1 2018, In: Nature Genetics. 50, 10, p. 1412-1425 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

893 Scopus citations

Genome-wide meta-analysis identifies 3 novel loci associated with stroke

for the MEGASTROKE consortium and the International Stroke Genetics Consortium, Dec 2018, In: Annals of neurology. 84, 6, p. 934-939 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

68 Scopus citations

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

MEGASTROKE Consortium, Dec 1 2018, In: Nature communications. 9, 1, 5141.

Research output: Contribution to journal › Article › peer-review

Open Access

105 Scopus citations

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

Neurology Working Group of the CHARGE Consortium, NINDS Stroke Genetics Network (SiGN), UK Young Lacunar DNA Study, MEGAST ROKE Consortium, AFGen Consortium, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, International Genomics of Blood Pressure (iGEN-BP) Consortium, INVENT Consortium, STA RNET BioBank Japan Cooperative Hospital Group, COMPASS Consortium, EPIC-CVD Consortium, EPIC-InterAct Consortium, International Stroke Genetics Consortium (ISGC) & METAST ROKE Consortium, Apr 1 2018, In: Nature Genetics. 50, 4, p. 524-537 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1095 Scopus citations

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

Davies, G., Lam, M., Harris, S. E., Trampush, J. W., Luciano, M., Hill, W. D., Hagenaars, S. P., Ritchie, S. J., Marioni, R. E., Fawns-Ritchie, C., Liewald, D. C. M., Okely, J. A., Ahola-Olli, A. V., Barnes, C. L. K., Bertram, L., Bis, J. C., Burdick, K. E., Christoforou, A., Derosse, P. & Djurovic, S. & 201 others, Espeseth, T., Giakoumaki, S., Giddaluru, S., Gustavson, D. E., Hayward, C., Hofer, E., Ikram, M. A., Karlsson, R., Knowles, E., Lahti, J., Leber, M., Li, S., Mather, K. A., Melle, I., Morris, D., Oldmeadow, C., Palviainen, T., Payton, A., Pazoki, R., Petrovic, K., Reynolds, C. A., Sargurupremraj, M., Scholz, M., Smith, J. A., Smith, A. V., Terzikhan, N., Thalamuthu, A., Trompet, S., Van Der Lee, S. J., Ware, E. B., Windham, B. G., Wright, M. J., Yang, J., Yu, J., Ames, D., Amin, N., Amouyel, P., Andreassen, O. A., Armstrong, N. J., Assareh, A. A., Attia, J. R., Attix, D., Avramopoulos, D., Bennett, D. A., Böhmer, A. C., Boyle, P. A., Brodaty, H., Campbell, H., Cannon, T. D., Cirulli, E. T., Congdon, E., Conley, E. D., Corley, J., Cox, S. R., Dale, A. M., Dehghan, A., Dick, D., Dickinson, D., Eriksson, J. G., Evangelou, E., Faul, J. D., Ford, I., Freimer, N. A., Gao, H., Giegling, I., Gillespie, N. A., Gordon, S. D., Gottesman, R. F., Griswold, M. E., Gudnason, V., Harris, T. B., Hartmann, A. M., Hatzimanolis, A., Heiss, G., Holliday, E. G., Joshi, P. K., Kähönen, M., Kardia, S. L. R., Karlsson, I., Kleineidam, L., Knopman, D. S., Kochan, N. A., Konte, B., Kwok, J. B., Le Hellard, S., Lee, T., Lehtimäki, T., Li, S. C., Liu, T., Koini, M., London, E., Longstreth, W. T., Lopez, O. L., Loukola, A., Luck, T., Lundervold, A. J., Lundquist, A., Lyytikäinen, L. P., Martin, N. G., Montgomery, G. W., Murray, A. D., Need, A. C., Noordam, R., Nyberg, L., Ollier, W., Papenberg, G., Pattie, A., Polasek, O., Poldrack, R. A., Psaty, B. M., Reppermund, S., Riedel-Heller, S. G., Rose, R. J., Rotter, J. I., Roussos, P., Rovio, S. P., Saba, Y., Sabb, F. W., Sachdev, P. S., Satizabal, C. L., Schmid, M., Scott, R. J., Scult, M. A., Simino, J., Slagboom, P. E., Smyrnis, N., Soumaré, A., Stefanis, N. C., Stott, D. J., Straub, R. E., Sundet, K., Taylor, A. M., Taylor, K. D., Tzoulaki, I., Tzourio, C., Uitterlinden, A., Vitart, V., Voineskos, A. N., Kaprio, J., Wagner, M., Wagner, H., Weinhold, L., Wen, K. H., Widen, E., Yang, Q., Zhao, W., Adams, H. H. H., Arking, D. E., Bilder, R. M., Bitsios, P., Boerwinkle, E., Chiba-Falek, O., Corvin, A., De Jager, P. L., Debette, S., Donohoe, G., Elliott, P., Fitzpatrick, A. L., Gill, M., Glahn, D. C., Hägg, S., Hansell, N. K., Hariri, A. R., Ikram, M. K., Jukema, J. W., Vuoksimaa, E., Keller, M. C., Kremen, W. S., Launer, L., Lindenberger, U., Palotie, A., Pedersen, N. L., Pendleton, N., Porteous, D. J., Räikkönen, K., Raitakari, O. T., Ramirez, A., Reinvang, I., Rudan, I., Rujescu, D., Schmidt, R., Schmidt, H., Schofield, P. W., Schofield, P. R., Starr, J. M., Steen, V. M., Trollor, J. N., Turner, S. T., Van Duijn, C. M., Villringer, A., Weinberger, D. R., Weir, D. R., Wilson, J. F., Malhotra, A., McIntosh, A. M., Gale, C. R., Seshadri, S., Mosley, T. H., Bressler, J., Lencz, T. & Deary, I. J., Dec 1 2018, In: Nature communications. 9, 1, 2098.

Research output: Contribution to journal › Article › peer-review

Open Access

432 Scopus citations

2016

Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies

The Cervical Artery Dissection and Ischemic Stroke Patients (CADISP) study, The METASTROKE consortium & The Neurology Working Group of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, the Stroke Genetics Network (SiGN), and the International Stroke Genetics Consortium (ISGC), Jun 1 2016, In: The Lancet Neurology. 15, 7, p. 695-707 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

130 Scopus citations

2014

Intermediary quantitative traits - An alternative in the identification of disease genes in asthma?

Sargurupremraj, M., Pukelsheim, K., Hofer, T. & Wjst, M., 2014, In: Genes and Immunity. 15, 1, p. 1-7 7 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Muralidharan Sargurupremraj

Research output

Search results