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Collaborations and top research areas from the last five years
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Oncogenic activation of EVC/EVC2 defines a therapeutically targetable subset of acute myeloid leukemia
Sui, P., Li, Y., Hong, J., Delma, C. R., Chen, S., Wang, J., Zhang, P., Han, S., Noor, A., Yang, H., Pang, Y., Luan, Y., Xu, M., Lee, J. & Yang, F. C., Jan 2026, In: Leukemia. 40, 1, p. 166-177 12 p.Research output: Contribution to journal › Article › peer-review
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Phf6 truncating mutation drives leukemogenesis via disrupted epigenetic regulation in mice
Guo, Y., Sui, P., Yang, H., Zhu, G., Li, Y., Chen, S., Zhao, Y., Ge, G., Eisa, Y. A., Delma, C. R., Medina, E. A., Zhang, P., Lee, J., Xu, M. & Yang, F. C., Mar 2026, In: Leukemia. 40, 3, p. 594-608 15 p.Research output: Contribution to journal › Article › peer-review
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HoxBlinc lncRNA reprograms CTCF-independent TADs to drive leukemic transcription and HSC dysregulation in NUP98-rearranged leukemia
Hamamoto, K., Zhu, G., Lai, Q., Lesperance, J., Luo, H., Li, Y., Nigam, N., Sharma, A., Yang, F. C., Claxton, D., Qiu, Y., Aplan, P. D., Xu, M. & Huang, S., Apr 1 2025, In: Journal of Clinical Investigation. 135, 7, e184743.Research output: Contribution to journal › Article › peer-review
Open Access4 Link opens in a new tab Scopus citations -
PSPC1 exerts an oncogenic role in AML by regulating a leukemic transcription program in cooperation with PU.1
Hong, J., Sui, P., Li, Y., Xu, K. Y., Lee, J. H., Wang, J., Chen, S., Zhang, P., Wingate, N., Noor, A., Yuan, Y., Hromas, R., Zhou, H., Hamamoto, K., Su, R., Yin, C. C., Ye, F., Quesada, A. E., Chen, J. & Huang, S. & 5 others, , Mar 6 2025, In: Cell Stem Cell. 32, 3, p. 463-478.e6Research output: Contribution to journal › Article › peer-review
Open Access8 Link opens in a new tab Scopus citations -
DDX18 coordinates nucleolus phase separation and nuclear organization to control the pluripotency of human embryonic stem cells
Shi, X., Li, Y., Zhou, H., Hou, X., Yang, J., Malik, V., Faiola, F., Ding, J., Bao, X., Modic, M., Zhang, W., Chen, L., Mahmood, S. R., Apostolou, E., Yang, F. C., Xu, M., Xie, W., Huang, X., Chen, Y. & Wang, J., Dec 2024, In: Nature communications. 15, 1, 10803.Research output: Contribution to journal › Article › peer-review
Open Access10 Link opens in a new tab Scopus citations
Datasets
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Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies
He, Y. (Creator), Khan, S. (Creator), Huo, Z. (Creator), Lv, D. (Creator), Zhang, X. (Creator), Liu, X. (Creator), Yuan, Y. (Creator), Hromas, R. (Creator), Xu, M. (Creator), Zheng, G. (Creator) & Zhou, D. (Creator), Figshare, 2020
DOI: 10.6084/m9.figshare.c.5075029, https://springernature.figshare.com/collections/Proteolysis_targeting_chimeras_PROTACs_are_emerging_therapeutics_for_hematologic_malignancies/5075029
Dataset
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Additional file 2 of Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies
He, Y. (Creator), Khan, S. (Creator), Huo, Z. (Creator), Lv, D. (Creator), Zhang, X. (Creator), Liu, X. (Creator), Yuan, Y. (Creator), Hromas, R. (Creator), Xu, M. (Creator), Zheng, G. (Creator) & Zhou, D. (Creator), Figshare, 2020
DOI: 10.6084/m9.figshare.12726547.v1, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_Proteolysis_targeting_chimeras_PROTACs_are_emerging_therapeutics_for_hematologic_malignancies/12726547/1
Dataset
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Additional file 2 of Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies
He, Y. (Creator), Khan, S. (Creator), Huo, Z. (Creator), Lv, D. (Creator), Zhang, X. (Creator), Liu, X. (Creator), Yuan, Y. (Creator), Hromas, R. (Creator), Xu, M. (Creator), Zheng, G. (Creator) & Zhou, D. (Creator), Figshare, 2020
DOI: 10.6084/m9.figshare.12726547, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_Proteolysis_targeting_chimeras_PROTACs_are_emerging_therapeutics_for_hematologic_malignancies/12726547
Dataset
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Additional file 3 of Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies
He, Y. (Creator), Khan, S. (Creator), Huo, Z. (Creator), Lv, D. (Creator), Zhang, X. (Creator), Liu, X. (Creator), Yuan, Y. (Creator), Hromas, R. (Creator), Xu, M. (Creator), Zheng, G. (Creator) & Zhou, D. (Creator), Figshare, 2020
DOI: 10.6084/m9.figshare.12726550, https://springernature.figshare.com/articles/dataset/Additional_file_3_of_Proteolysis_targeting_chimeras_PROTACs_are_emerging_therapeutics_for_hematologic_malignancies/12726550
Dataset
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Additional file 3 of Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies
He, Y. (Creator), Khan, S. (Creator), Huo, Z. (Creator), Lv, D. (Creator), Zhang, X. (Creator), Liu, X. (Creator), Yuan, Y. (Creator), Hromas, R. (Creator), Xu, M. (Creator), Zheng, G. (Creator) & Zhou, D. (Creator), Figshare, 2020
DOI: 10.6084/m9.figshare.12726550.v1, https://springernature.figshare.com/articles/dataset/Additional_file_3_of_Proteolysis_targeting_chimeras_PROTACs_are_emerging_therapeutics_for_hematologic_malignancies/12726550/1
Dataset