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Maria E Gaczynska

  • 3418 Citations
  • 26 h-Index
1985 …2019
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  • 6 Similar Profiles
Proteasome Endopeptidase Complex Medicine & Life Sciences
Erythrocyte Membrane Medicine & Life Sciences
Peptide Hydrolases Medicine & Life Sciences
Proteolysis Medicine & Life Sciences
Membrane Proteins Medicine & Life Sciences
Membranes Chemical Compounds
Erythrocytes Medicine & Life Sciences
Atomic Force Microscopy Medicine & Life Sciences

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Projects 2002 2015

Proteasome Function During Aging in Extraordinarily Long-Lived Naked Mole-Rats

Buffenstein, R., Osmulski, P. A., Gaczynska, M. E. & Osmulski, P.

National Institutes of Health

9/1/13 → 7/3/15

Project: Research project

Mole Rats
Proteasome Endopeptidase Complex
Oxidative Stress
Proteins
Heat-Shock Proteins

Mechanisms of Regulation of the Proteasome Activities

Gaczynska, M. E.

National Institutes of Health

2/1/04 → 1/31/10

Project: Research project

Proteasome Endopeptidase Complex
Ligands
Peptides
Atomic Force Microscopy
Fluorescence Spectrometry

Aging /Caloric Restriction /Cytosolic Protease

Gaczynska, M. E.

National Institutes of Health

9/1/02 → 2/28/05

Project: Research project

Caloric Restriction
Proteasome Endopeptidase Complex
Proteolysis
Peptide Hydrolases
Leucyl Aminopeptidase

Research Output 1985 2019

  • 3418 Citations
  • 26 h-Index
  • 90 Article
  • 1 Letter
2 Citations (Scopus)

Adipokines deregulate cellular communication via epigenetic repression of gap junction loci in obese endometrial cancer

Polusani, S. R., Huang, Y. W., Huang, G., Chen, C. W., Wang, C. M., Lin, L. L., Osmulski, P., Lucio, N. D., Liu, L., Hsu, Y. T., Zhou, Y., Lin, C. L., Aguilera-Barrantes, I., Valente, P. T., Kost, E. R., Chen, C., Shim, E., Lee, S., Ruan, J., Gaczynska, M. E. & 7 others, Yan, P., Goodfellow, P. J., Mutch, D. G., Jin, V. X., Nicholson, B. J., Huang, H. & Kirma, N. B., Jan 1 2019, In : Cancer Research. 79, 1, p. 196-208 13 p.

Research output: Contribution to journal › Article

Epigenetic Repression
Adipokines
Gap Junctions
Endometrial Neoplasms
Communication

Pipecolic esters as minimized templates for proteasome inhibition

Giletto, M. B., Osmulski, P., Jones, C. L., Gaczynska, M. E. & Tepe, J. J., Jan 1 2019, In : Organic and Biomolecular Chemistry. 17, 10, p. 2734-2746 13 p.

Research output: Contribution to journal › Article

Proteasome Endopeptidase Complex
inhibitors
esters
Esters
templates
3 Citations (Scopus)

Proline- and Arginine-Rich Peptides as Flexible Allosteric Modulators of Human Proteasome Activity

Giziynska, M. A., Witkowska, J., Karpowicz, P., Rostankowski, R., Chocron, E. S., Pickering, A. M., Osmulski, P., Gaczynska, M. E. & Jankowska, E., Jan 1 2018, (Accepted/In press) In : Journal of Medicinal Chemistry.

Research output: Contribution to journal › Article

Proteasome Endopeptidase Complex
Proline
Human Activities
Arginine
Peptides
4 Citations (Scopus)

Small Molecule Modulation of Proteasome Assembly

Njomen, E., Osmulski, P., Jones, C. L., Gaczynska, M. E. & Tepe, J. J., May 23 2018, (Accepted/In press) In : Biochemistry.

Research output: Contribution to journal › Article

Proteasome Endopeptidase Complex
Intrinsically Disordered Proteins
Proteolysis
Modulation
Molecules
6 Citations (Scopus)

Cellular cholesterol regulates monocyte deformation

Saha, A. K., Dallo, S. F., Detmar, A. L., Osmulski, P., Gaczynska, M. E., Huang, H. & Ramasubramanian, A. K., 2017, In : Journal of Biomechanics. 52, p. 83-88 6 p.

Research output: Contribution to journal › Article

Cholesterol
Monocytes
Formability
Phosphorylation
Membrane Fluidity